Create issue ticket

40 Possible Causes for Prominent or Protruding Philtrum

  • Osteoporosis-Oculocutaneous Hypopigmentation Syndrome

    […] or protruding philtrum elongated philtrum more Head And Neck Eyes: blepharophimosis short palpebral fissures (in some patients) Head And Neck Ears: small ears Cardiovascular[malacards.org] […] anterior fossa (rare) Prenatal Manifestations Placenta And Umbilical Cord: placental abnormality (in some patients) Head And Neck Face: micrognathia retrognathia hairy forehead prominent[malacards.org]

  • Macrocephaly

    She also had macrocephaly, frontal bossing, hypertelorism, wide nasal bridge, small alae nares, short philtrum, prominent upper lip, and low-set, protruding ears.[ncbi.nlm.nih.gov]

  • Cornelia De Lange Syndrome

    […] or protruding philtrum (area between upper lip and nose) Broad or depressed nasal bridge Small chin, may appear more square in adolescence or adulthood Thin upper lip, or[medicalhomeportal.org] […] major or minor) Facial Features : Synophrys (eyebrows that meet at the midline) plus 3 or more of the following: Long eyelashes Short nasal bridge and anteverted nares Long, prominent[medicalhomeportal.org]

  • Wolf Hirschhorn Syndrome

    The facial phenotype is characterized by hypertelorism, protruding eyes, prominent glabella, broad nasal bridge and short philtrum.[ncbi.nlm.nih.gov] […] glabella, hypertelorism, high-arched eyebrows, broad nasal bridge, protruding eyes, epicanthal folds, short philtrum, downturned corners of mouth, micrognathia, and often[mjdrdypu.org] The examination revealed severe hypotonia and dysmorphic features such as microcephaly, high forehead, prominent glabella, hypertelorism, depressed nasal bridge, short philtrum[mjdrdypu.org]

  • Distal Renal Tubular Acidosis

    Their facial features are unique with prominent cheeks, well-defined philtrum, large bulbous nose, V-shaped upper lip border, full lower lip, open mouth with protruded tongue[ncbi.nlm.nih.gov]

  • Branchio-Oculo-Facial Syndrome

    […] upper lip with an unusually broad and prominent philtrum, and full mouth.[orpha.net] […] with linear skin lesions behind the ears ('burn-like' lesions), congenital strabismus, obstructed nasolacrimal ducts, a broad nasal bridge with a flattened nasal tip, a protruding[orpha.net]

  • Kabuki Syndrome

    […] ears missing and widely-spaced teeth "trapezoid philtrum" hypotonia feeding problems mental retardation (most slight or moderate) growth retardation prominent finger pads[radiopaedia.org] […] is equal. characteristic facies long palpebral fissures eversion of lower eyelid arched eyebrows sparseness of lateral half of the eyebrows hypertelorism epicanthal folds protruding[radiopaedia.org]

  • Trichorhinophalangeal Syndrome

    […] lip as well as a long, protruding upper lip; underdeveloped cheek bones (malar hypoplasia); and/or an abnormally prominent upper jaw bone (maxilla).[rarediseases.org] These may include a pear-shaped or rounded (bulbous) nose with small, underdeveloped nostrils (hypoplastic alae nasi); an abnormally long broad groove (philtrum) on the upper[rarediseases.org]

  • Naguib Syndrome

    0000343 Proptosis Bulging eye Eyeballs bulging out Prominent eyes Prominent globes Protruding eyes [ more ] 0000520 Ptosis Drooping upper eyelid 0000508 5%-29% of people[rarediseases.info.nih.gov] Downslanted palpebral fissures Downward slanting of the opening between the eyelids 0000494 Eyelid coloboma Cleft eyelid Notched eyelid [ more ] 0000625 Glaucoma 0000501 Long philtrum[rarediseases.info.nih.gov]

  • Acrocallosal Syndrome

    , long prominent philtrum, posteriorly located small mandible, and an open mouth with a protruding tongue (fig. 1 A-C).[karger.com] A-C Dysmorphological facial features with prominent forehead, marked hypertelorism, low-set ears, short nose with anteverted nostrils, long prominent philtrum, posteriorly[karger.com] […] located small mandible and an open mouth with a protruding tongue.[karger.com]

Further symptoms