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22 Possible Causes for Prominent or Protruding Philtrum

  • Osteoporosis-Oculocutaneous Hypopigmentation Syndrome

    […] or protruding philtrum elongated philtrum more Head And Neck Eyes: blepharophimosis short palpebral fissures (in some patients) Head And Neck Ears: small ears Cardiovascular[malacards.org] […] anterior fossa (rare) Prenatal Manifestations Placenta And Umbilical Cord: placental abnormality (in some patients) Head And Neck Face: micrognathia retrognathia hairy forehead prominent[malacards.org]

  • Branchio-Oculo-Facial Syndrome

    […] upper lip with an unusually broad and prominent philtrum, and full mouth.[orpha.net] […] with linear skin lesions behind the ears ('burn-like' lesions), congenital strabismus, obstructed nasolacrimal ducts, a broad nasal bridge with a flattened nasal tip, a protruding[orpha.net]

  • Macrocephaly

    She also had macrocephaly, frontal bossing, hypertelorism, wide nasal bridge, small alae nares, short philtrum, prominent upper lip, and low-set, protruding ears.[ncbi.nlm.nih.gov]

  • Wolf Hirschhorn Syndrome

    The facial phenotype is characterized by hypertelorism, protruding eyes, prominent glabella, broad nasal bridge and short philtrum.[ncbi.nlm.nih.gov] […] glabella, hypertelorism, high-arched eyebrows, broad nasal bridge, protruding eyes, epicanthal folds, short philtrum, downturned corners of mouth, micrognathia, and often[mjdrdypu.org] [ncbi.nlm.nih.gov] The facial phenotype is characterized by hypertelorism , protruding eyes, prominent glabella, broad nasal bridge and short philtrum.[symptoma.com]

  • Distal Renal Tubular Acidosis

    Their facial features are unique with prominent cheeks, well-defined philtrum, large bulbous nose, V-shaped upper lip border, full lower lip, open mouth with protruded tongue[ncbi.nlm.nih.gov]

  • Naguib Syndrome

    0000343 Proptosis Bulging eye Eyeballs bulging out Prominent eyes Prominent globes Protruding eyes [ more ] 0000520 Ptosis Drooping upper eyelid 0000508 5%-29% of people[rarediseases.info.nih.gov] Downslanted palpebral fissures Downward slanting of the opening between the eyelids 0000494 Eyelid coloboma Cleft eyelid Notched eyelid [ more ] 0000625 Glaucoma 0000501 Long philtrum[rarediseases.info.nih.gov]

  • Kabuki Syndrome

    […] ears missing and widely-spaced teeth "trapezoid philtrum" hypotonia feeding problems mental retardation (most slight or moderate) growth retardation prominent finger pads[radiopaedia.org] […] is equal. characteristic facies long palpebral fissures eversion of lower eyelid arched eyebrows sparseness of lateral half of the eyebrows hypertelorism epicanthal folds protruding[radiopaedia.org]

  • Hyperextensible Joints

    , small thorax with wide spaced hypoplastic nipples, depressed nasal bridge, small dysmorphic ears, protruding philtrum, short palpebral fissures [30] Prominent forehead and[kundoc.com] […] small philtrum, macrognathia, dysmorphic ears [38] Synophrys, prominent nasal bridge, high arched palate [25] Short philtrum, dysmorphic ears, clinodactyly [39] Short neck[kundoc.com] Dysmorphic features Large and protruding ears, shallow orbits, depressed nasal bridge, narrow and upturned nose [33] High forehead, prominent brows, large tip of the nose,[kundoc.com]

  • Trichorhinophalangeal Syndrome

    […] lip as well as a long, protruding upper lip; underdeveloped cheek bones (malar hypoplasia); and/or an abnormally prominent upper jaw bone (maxilla).[rarediseases.org] These may include a pear-shaped or rounded (bulbous) nose with small, underdeveloped nostrils (hypoplastic alae nasi); an abnormally long broad groove (philtrum) on the upper[rarediseases.org]

  • Ectodermal Dysplasia-Sensorineural Deafness Syndrome

    […] bridge of nose Prominent nasal root Protruding bridge of nose Protruding nasal bridge [ more ] 0000426 Radial deviation of finger 0009466 Sensorineural hearing impairment[rarediseases.info.nih.gov] 0000407 Short philtrum 0000322 Sparse and thin eyebrow Thin, sparse eyebrows 0000535 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Trichiasis Ingrown eyelashes[rarediseases.info.nih.gov] […] chest 0000767 Photophobia Extreme sensitivity of the eyes to light Light hypersensitivity [ more ] 0000613 Prominent nasal bridge Elevated nasal bridge High nasal bridge Prominent[rarediseases.info.nih.gov]

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