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42 Possible Causes for Prominent Perivascular Spaces

  • Rocky Mountain Spotted Fever

    Four of these were abnormal: 1 patient had “prominent perivascular spaces,” 1 had focal arterial infarctions, 1 had diffuse edema, and 1 had meningeal enhancement.[neurology.org]

  • Coffin-Lowry Syndrome

    Cranial CT and MRI are often normal although thickened calvarium,hydrocephalus, callosal dysgenesis, abnormal gyrification and leukoencephalopathy with prominent perivascular[alliedacademies.org] spaces have been reported [ 19 - 22 ].[alliedacademies.org]

  • PTEN Hamartoma Tumor Syndrome

    Brain MRI typically shows prominent Virchow-Robin/perivascular spaces with a posterior predominance (Figure 1).[consultqd.clevelandclinic.org] Review of his brain MRI, reported as normal, showed slightly prominent perivascular spaces on T2-weighted imaging with a posterior predominance.[consultqd.clevelandclinic.org] Sagittal (left) and axial (right) T2-weighted images with prominent perivascular spaces showing a posterior predominance in a young child with germline PTEN gene mutation.[consultqd.clevelandclinic.org]

  • Lacunar Infarction

    Recently, the importance of cerebral microbleeds and prominent perivascular spaces has been emphasized as a significant neuroradiological manifestation of small vessel disease[ghrnet.org] […] or enlarged perivascular spaces and these are the most important predictors of cognitive impairment and subcortical vascular dementia in the first-ever lacunar infarct patients[ghrnet.org] […] typical neuroimaging manifestations of the cerebral small vessel diseases or microangiopathy are leukoaraiosis or white matter hyperintensities, cerebral microbleeds, and prominent[ghrnet.org]

  • Pseudo-Hurler Polydystrophy

    The estimated incidence is 1:100,000. macrocephaly prominent perivascular spaces pachymeningiopathy J-shaped sella concave articular surface of mandibular condyle cord compression[radiopaedia.org] perivascular spaces hepatosplenomegaly History and etymology It is named after Gertrud Hurler (1889-1965), a German paediatrician 1 .[radiopaedia.org] […] involvement cardiac valve disease: early onset severe regurgitation and stenosis coronary artery disease cardiomegaly: initially hypertrophic then dilated Other features include prominent[radiopaedia.org]

  • Mucopolysaccharidosis 1H

    The estimated incidence is 1:100,000. macrocephaly prominent perivascular spaces pachymeningiopathy J-shaped sella concave articular surface of mandibular condyle cord compression[radiopaedia.org] , cortical atrophy, and enlargement of the perivascular spaces.[surgicalneurologyint.com] perivascular spaces hepatosplenomegaly History and etymology It is named after Gertrud Hurler (1889-1965), a German paediatrician 1 .[radiopaedia.org]

  • Lissencephaly

    Most patients with LIS1 mutations demonstrated posterior agyria (grade 3a, 55.3%) with thin corpus callosum (50%) and prominent perivascular spaces (67.4%).[ncbi.nlm.nih.gov]

  • Macrocephaly-Developmental Delay Syndrome

    Brain MRI typically shows prominent Virchow-Robin/perivascular spaces with a posterior predominance (Figure 1).[consultqd.clevelandclinic.org] Review of his brain MRI, reported as normal, showed slightly prominent perivascular spaces on T2-weighted imaging with a posterior predominance.[consultqd.clevelandclinic.org] Sagittal (left) and axial (right) T2-weighted images with prominent perivascular spaces showing a posterior predominance in a young child with germline PTEN gene mutation.[consultqd.clevelandclinic.org]

  • Mucopolysaccharidosis 1 H-S

    The estimated incidence is 1:100,000. macrocephaly prominent perivascular spaces pachymeningiopathy J-shaped sella concave articular surface of mandibular condyle cord compression[radiopaedia.org] perivascular spaces hepatosplenomegaly History and etymology It is named after Gertrud Hurler (1889-1965), a German paediatrician 1 .[radiopaedia.org] […] involvement cardiac valve disease: early onset severe regurgitation and stenosis coronary artery disease cardiomegaly: initially hypertrophic then dilated Other features include prominent[radiopaedia.org]

  • Kondoh Syndrome

    MRI of the brain in a Japanese CLS patient also revealed prominent perivascular spaces.[the-medical-dictionary.com] Prominent periventricular Virchow-Robin spaces in MPS corresponded pathologically to perivascular accumulation of glycosaminoglycans within foam cells in the Virchow-Robin[the-medical-dictionary.com]

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