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55 Possible Causes for Prominent Sulci, Severe Anemia

  • Hypoxia

    Pure cerebral hypoxia can occur due to pulmonary disease, altitude sickness, or severe anemia.[encyclopedia.com] Grossly, the lesion was marked by preserved gyral crests and involved sulci, resulting in prominent, mushroom-shaped gyri.[emedicine.medscape.com] Acute hypoxia is often a result of acute hemolysis with severe anemia resulting in reduced oxygen content in blood.[bloodjournal.org]

  • Alcohol Dementia

    Because people may not eat an adequate diet, they may also develop severe vitamin and other nutritional deficiencies.[merckmanuals.com] The CT showed prominent sulci and gyri with deep white matter changes. There were no other abnormalities.[gponline.com] Effects of Prolonged Alcohol Use Type of Problem Effects Nutritional Low folate (folic acid) levels Anemia (fatigue, weakness, and light-headedness) Birth defects Low thiamin[merckmanuals.com]

  • Cerebral Cortical Atrophy

    In severe cases, thrombocytopenia and neutropenia may accompany anemia mimicking leukemia or aplastic anemia.[scopemed.org] Imaging wise feature of cerebral cortical atrophy Generalized prominence of hemisphere cortical sulci on CT or MRI in mild cases.[neuroradiologycases.com] Characteristic features include prominent cerebral sulci (i.e. cortical atrophy) and v entriculomegaly (i.e. central atrophy) without bulging of the third ventricular recesses[radiopaedia.org]

  • Vitiligo

    Blood tests can help diagnose other problems that may go along with vitiligo, such as thyroid problems, diabetes or anemia.[healthline.com] […] joints (versus between the joints), the nose tip and alae (versus nasal sulci), axilla and elbows.[ncbi.nlm.nih.gov] The latter, as outlined in several studies performed over the last decades, represent the most frequent autoimmune disorders associated with vitiligo ( 54, 58, 66 – 73 ).[frontiersin.org]

  • Pyridoxine Dependency Syndrome

    In their study, severe acute pyridoxine deficiency in young ducklings was also characterized by severe anemia while chronic pyridoxine deficiency in older ducklings produced[medical-dictionary.thefreedictionary.com] C T scan showed prominent cerebral sulci and interhemispheric fissure but n o anomalies or calcification.[dev.docslide.net] One type of hereditary anemia and several metabolic diseases are effectively treated with high doses of pyridoxine.[encyclopedia.com]

  • Chronic Daily Headaches

    severe iron-deficiency anemia.[nhlbi.nih.gov] Finally ( viii ), we found that (like CSD) the spreading phenomenon did not cross prominent sulci (e.g., the parieto-occipital sulcus).[doi.org] Over the following week, she developed a severe hemolytic anemia with hemoglobin falling from 12.5 to 5.0 g/dL, which was treated with blood transfusions and high doses of[livertox.nih.gov]

  • Hypertensive Encephalopathy

    Adult Dose 5-300 mcg/min IV infusion, titrate to desired BP Pediatric Dose Not established Contraindications Documented hypersensitivity; severe anemia, shock, postural hypotension[razianesth.freeservers.com] There was complete resolution of cerebral edema in all patients and mild interval prominence of the cerebral sulci, which can indicate cerebral volume loss, in three out of[bloodjournal.org] Severe hypertension, renal dysfunction, thrombocytopenia, and anemia were present.[ncbi.nlm.nih.gov]

  • Isolated Congenital Sclerocornea

    Thrombocytopenia Immunodeficiency SOURCES: OMIM MESH UMLS MONDO SCTID ORPHANET More info about SEVERE COMBINED IMMUNODEFICIENCY WITH MICROCEPHALY, GROWTH RETARDATION, AND[mendelian.co] Head MRI showed prominent sulci and abnormal T2 prolongation in the cerebral white matter and brainstem.[profiles.stanford.edu] […] deficiency; combined immunodeficiency-microcephaly-growth retardation-sensitivity to ionizing radiation syndrome; nhej1 deficiency Related symptoms: Microcephaly Growth delay Anemia[mendelian.co]

  • Rasmussen Syndrome

    anemia.[doi.org] Axial T1 FLAIR MRI scan of the brain showing prominent sulci, dilated lateral ventricle, and hemiatrophy on the left. Figure 7 Figure 7: Rasmussen Encephalitis.[ispub.com] Prominence of ventricles with widening of the cerebellar sulci was suggestive of cerebellar atrophy. (Patient till date has no cerebellar signs.)[njcponline.com]

  • Combined Oxidative Phosphorylation Defect Type 11

    Acquired causes of lactic acidosis include cardiopulmonary disease, severe anemia, malignancy, diabetes mellitus, hepatic failure and postconvulsion status or can be drug-related[mrineonatalbrain.com] […] congenital 4, autosomal recessive 612541 G6PD Xq28 Favism 134700 Hemolytic anemia due to G6PD deficiency 300908 Resistance to malaria due to G6PD deficiency 611162 GAA 17q25.3[institutobernabeu.com] Congestive heart failure Bundle branch block Progressive external ophthalmoplegia Optic neuropathy Abnormality of the cerebral white matter Apathy Severe muscular hypotonia[mendelian.co]

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