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228 Possible Causes for Prothrombin Time Decreased

  • Anticardiolipin Antibody Syndrome

    Antiphospholipid antibody syndrome, also known as Hughes syndrome, is a hypercoagulable disorder that increases the risk of recurrent vascular thrombosis. We present a case of 26-year-old female who developed massive bilateral pulmonary emboli after being started on oral contraceptive pills. Further work-up of the[…][]

  • Aspartylglucosaminuria

    OBJECTIVE: To ascertain whether being a carrier of an autosomal recessive disease, aspartylglucosaminuria (AGU), predisposes to chronic arthritis, as does AGU disease. METHODS: A group of 173 unrelated patients with rheumatoid arthritis (RA) but with no family members with AGU each gave a blood sample for AGUFin[…][]

  • Cholelithiasis

    Prothrombin is reduced and coagulation time prolonged when bile flow is obstructed, increasing risk of bleeding or hemorrhage. Keep patient NPO as necessary.[] Decreases GI secretions and motility. Insert NG tube, connect to suction, and maintain patency as indicated.[]

  • Coagulation Abnormalities

    […] and decrease in prothrombin activity.[] Decreased prothrombin (PT) time Potential for injury related to formation of venous thrombus A patient who has a lower than normal PT may be at risk for formation of a venous[] , prothrombin time, activated partial thromboplastin time (aPTT), fibrinogen concentration, antithrombin activity, D-dimer concentration, protein C activity, plasmin inhibition[]

  • Thrombocytopenia

    The platelet count was again 1000/μL; platelets were markedly decreased on a smear. Prothrombin and partial thromboplastin time results were within normal limits.[]

  • Obstructive Jaundice

    time(Decreased absroption of fat solube vitamins A,D,E,K(decreased factorXI ,XII ,platelets)Renal functionsRenal vasoconstrictionActivation of complement system causing peritubular[] […] into theblood, and bile excretion from the body is incompleteHepatic functionsProtein synthesis,Reticulo-endothelial functionHepatic metabolismCoagulation defect..increased prothrombin[]

  • Bee Sting

    The prothrombin index decreased to 28%, prothrombine time was prolonged to 34". Fibrin degradation products were present in serum.[]

  • Liver Cirrhosis

    Fifty-three patients (Group B) matched for age, sex, and baseline alanine aminotransferase, aspartate aminotransferase, albumin, total bilirubin, prothrombin time, and model[] RESULTS: Interleukin-6 and tumor necrosis factor alpha levels markedly decreased, and interleukin-10 level apparently increased in Group A at 2 and 4 weeks after treatment[]

  • Portal Cirrhosis

    As the liver synthesizes clotting factors, this will be impaired in disease; prothrombin time will increase. And coagulation studies will be deranged as well.[] Albumin will decrease and this is a marker for reduced synthetic function of the liver.[]

  • Pulmonary Tumor Embolism

    Prothrombin time was slightly prolonged to 15.4 seconds but partial thromboplastin time and fibrinogen were in normal range.[] Pulmonary function test showed normal ventilator pattern, but decreased diffusing capacity of the lungs for carbon monoxide (DLCO 68%).[]

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