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335 Possible Causes for Prothrombin Time Decreased

  • Phenobarbital

    […] by the prothrombin time .[rxlist.com] Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (name previously used: bishydorxycoumarin) and causes a decrease in anticoagulant activity as measured[rxlist.com] Phenobarbital can induce hepatic microsomal enzymes resulting in increased metabolism and decreased anticoagulant response of oral anticoagulants (e.g., warfarin , acenocournarol[rxlist.com]

  • Bee Sting

    The prothrombin index decreased to 28%, prothrombine time was prolonged to 34". Fibrin degradation products were present in serum.[ncbi.nlm.nih.gov]

  • Chloral Hydrate

    This prospective, randomized, and observer-blinded study was performed to evaluate the effects of oral chloral hydrate on perioperative psychological and behavioral phenomena in children. In total, 100 boys (age, 1-5 years) scheduled for day-case unilateral orchiopexy were randomly allocated into 2 groups and orally[…][ncbi.nlm.nih.gov]

  • Meningococcemia

    The mean fibrinogen level increased from 62 to 192 mg/dl, the prothrombin time (PT) decreased from a mean of 32.4 seconds to 15.1 seconds, and the mean activated partial thromboplastin[ncbi.nlm.nih.gov]

  • Autoimmune Pancreatitis

    On admission, laboratory examinations revealed severe anemia with a markedly prolonged activated partial prothrombin time, a decreased level of factor VIII (FVIII) activity[ncbi.nlm.nih.gov]

  • Aspartylglucosaminuria

    Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by mutations in the gene for aspartylglucosaminidase (AGA). This enzyme participates in glycoprotein degradation in lysosomes. AGU results in progressive mental retardation, and no curative therapy is currently available. We have here characterized[…][ncbi.nlm.nih.gov]

  • Hepatocellular Carcinoma

    Five days after the last intervention, her prothrombin time decreased to 10%, and her activated partial thromboplastin time (APTT) lengthened to 265.1 sec.[ncbi.nlm.nih.gov]

  • Anticardiolipin Antibody Syndrome

    Antiphospholipid antibody syndrome, also known as Hughes syndrome, is a hypercoagulable disorder that increases the risk of recurrent vascular thrombosis. We present a case of 26-year-old female who developed massive bilateral pulmonary emboli after being started on oral contraceptive pills. Further work-up of the[…][ncbi.nlm.nih.gov]

  • Obstructive Jaundice

    time(Decreased absroption of fat solube vitamins A,D,E,K(decreased factorXI ,XII ,platelets)Renal functionsRenal vasoconstrictionActivation of complement system causing peritubular[slideshare.net] […] into theblood, and bile excretion from the body is incompleteHepatic functionsProtein synthesis,Reticulo-endothelial functionHepatic metabolismCoagulation defect..increased prothrombin[slideshare.net]

  • Honey

    The prothrombin index decreased to 28%, prothrombine time was prolonged to 34". Fibrin degradation products were present in serum.[ncbi.nlm.nih.gov]

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