Create issue ticket

461 Possible Causes for Proximal Lower Limb Weakness

  • Limb-Girdle Muscular Dystrophy Type 2G

    Physical examination at admission revealed increased calf, difficulties performing extraocular eye movement and lower limb proximal weakness.[bmcclinpathol.biomedcentral.com] ) of progressive proximal upper and lower limb muscle weakness and atrophy.[rarediseases.info.nih.gov] […] muscular dystrophy characterized by a variable onset (ranging from infancy to adolescence) of progressive proximal upper and lower limb muscle weakness and atrophy.[malacards.org]

  • Limb-Girdle Muscular Dystrophy Type 1H

    […] both the upper and lower limbs (Bisceglia et al., 2010).[malacards.org] Five subjects presented with a slowly progressive proximal muscle weakness, in both upper and lower limbs, with onset during the fourth-fifth decade of life, which fulfilled[moh-it.pure.elsevier.com] LGMD1H is a form of muscular dystrophy characterized by a slow progression of proximal muscle weakness in both upper and lower limbs affecting several members of a four generations[telethon.it]

  • Diabetic Amyotrophy

    We reviewed thirteen patients with this disorder, all of whom had significant proximal lower limb wasting and weakness as the predominant feature and eleven of whom had pain[ncbi.nlm.nih.gov] […] motor neuron weakness involving predominantly the proximal muscles of the lower limbs, weakness that is not confined to one nerve or nerve root distribution and exclusion[ncbi.nlm.nih.gov] Only five patients displayed asymmetric proximal lower limb wasting, weakness and pain, motor deficits in the remainder being either unilateral or bilateral and symmetrical[ncbi.nlm.nih.gov]

  • Limb-Girdle Muscular Dystrophy Type 1E

    Fukutin related protein LGMD 2J Onset 1 st to 3 rd decade, proximal lower limb weakness, mild distal weakness, progressive weakness causes loss of ambulation Titin LMGD 2K[jcdr.net] […] conduction defect Dilated cardiomyopathy LGMD1E 9–49 years (30 average) Proximal lower and upper limb muscle weakness Contractures Difficulties swallowing Caveolinopathy[encyclopedia.com] His younger brother also had similar proximal lower limbs weakness; however he committed suicide at age 31 years.[bmcresnotes.biomedcentral.com]

  • Limb-Girdle Muscular Dystrophy Type 1G

    […] characterized by slowly progressive proximal muscle weakness affecting the upper and lower limbs.[mendelian.co] […] muscular dystrophy 1F (LGMD1F) [MIM:608423]: An autosomal dominant myopathy characterized by proximal muscle weakness primarily affecting the lower limbs, but also affecting[genecards.org] The initial symptoms were proximal lower limbs involvement and weakness followed by upper limbs proximal weakness.[doi.org]

  • Limb-Girdle Muscular Dystrophy Type 1F

    Autosomal dominant limb-girdle muscular dystrophy-2 is a myopathy characterized by proximal muscle weakness primarily affecting the lower limbs, but also affecting the upper[ncbi.nlm.nih.gov] […] conduction defect Dilated cardiomyopathy LGMD1E 9–49 years (30 average) Proximal lower and upper limb muscle weakness Contractures Difficulties swallowing Caveolinopathy[encyclopedia.com] Definition An autosomal dominant myopathy characterized by proximal muscle weakness primarily affecting the lower limbs, but also affecting the upper limbs in most patients[uniprot.org]

  • Chronic Alcoholism

    He presented with bilateral, proximal upper and lower limb weakness, limb girdle wasting, bilaterally reduced Achilles tendon reflexes, and bilateral stocking-type sensory[ncbi.nlm.nih.gov]

  • Limb-Girdle Muscular Dystrophy Type 2B

    She began to experience proximal muscle weakness of both lower limbs without obvious inducement, which markedly increased when she climbed the stairs or stood up after squatting[ncbi.nlm.nih.gov] […] conduction defect Dilated cardiomyopathy LGMD1E 9–49 years (30 average) Proximal lower and upper limb muscle weakness Contractures Difficulties swallowing Caveolinopathy[encyclopedia.com] limb muscle weakness Lower extremity weakness Lower limb weakness Muscle weakness in lower limbs [ more ] 0007340 Muscular dystrophy 0003560 Pectoralis amyotrophy Wasting[rarediseases.info.nih.gov]

  • Polyneuropathy

    Severe weakness at lower limbs was noticed, mainly at proximal sites.[scielo.br] ) (p   0.0009), more proximal weakness (p   0.03), more gait abnormality (p   0.03) and more abnormal NCS.[journals.plos.org] They described a patient submitted to BS for morbid obesity which developed acute and severe onset of lower limb proximal weakness and pain.[scielo.br]

  • Limb-Girdle Muscular Dystrophy Type 2C

    Physical examination at admission revealed increased calf, difficulties performing extraocular eye movement and lower limb proximal weakness.[bmcclinpathol.biomedcentral.com] […] conduction defect Dilated cardiomyopathy LGMD1E 9–49 years (30 average) Proximal lower and upper limb muscle weakness Contractures Difficulties swallowing Caveolinopathy[encyclopedia.com] LGMD1B is characterised by predominant proximal weakness in the lower limbs, contractures and cardiac arrhythmias and dilated cardiomyopathy with risk of sudden death.[mdfgauteng.org]

Further symptoms