Proximal Muscle Wasting: Causes & Reasons

Possible Causes for Proximal Muscle Wasting

Proximal muscle wasting and weakness. Diabetes or impaired glucose tolerance. Gonadal dysfunction, reduced libido. Hypertension. Nephrolithiasis. [patient.info]

Autosomal Recessive Limb-Girdle Muscular Dystrophy

Abstract Characterized by proximal muscle weakness and wasting, limb-girdle muscular dystrophies (LGMDs) are a heterogeneous group of clinical disorders. [ncbi.nlm.nih.gov]

muscle weakness and wasting of the pelvic and shoulder girdles with onset that usually occurs during the second or third decade of life. [orpha.net]

Clinical features include variable age of onset, proximal limb muscle weakness and wasting predominantly affecting the pelvic girdle, and variable course between siblings. [ncbi.nlm.nih.gov]

Diabetic Amyotrophy

That's because not everyone with type 2 diabetes has the symptoms of muscle wasting and weakness of diabetic proximal neuropathy. [a-diabetic-life.com]

It is characterised by a weakness and wasting of proximal muscles of the lower limbs with associated pain. [ncbi.nlm.nih.gov]

We report the case of 71-year-old male who was once diagnosed as having diabetic amyotrophy, because of pronounced wasting in proximal muscles, massive weight loss, and development [ncbi.nlm.nih.gov]

Mauriac Syndrome

Common presenting features include short stature, growth retardation, moon facies, protuberant abdomen, and proximal muscle wasting. [theijcp.org]

Common presenting features include short stature, growth retardation, moon facies, protuberant abdomen and proximal muscle wasting. [onlinelibrary.wiley.com]

muscle wasting and moon face. [jomrjournal.org]

Limb-Girdle Muscular Dystrophy Type 1G

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles). [connects.catalyst.harvard.edu]

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the Hips and Shoulders (the pelvic and shoulder girdles). [familydiagnosis.com]

[…] and characterised by predominant weakness and wasting in proximal limb and axial muscles. [els.net]

Myopathy and Diabetes mellitus

That's because not everyone with type 2 diabetes has the symptoms of muscle wasting and weakness of diabetic proximal neuropathy. [a-diabetic-life.com]

[…] cramps and occasional dysphagia 198 TK2, which encodes thymidine kinase 2 Ptosis, scapular winging, facial and proximal muscle weakness and wasting, dysphagia and respiratory [nature.com]

Weakness occurs mainly in the proximal muscles such as the upper arms, shoulders, pelvis and thighs. [diabeteshealthysolutions.com]

Diaphyseal Medullary Stenosis with Malignant Fibrous Histiocytoma

muscle weakness Weakness in muscles of upper arms and upper legs 0003701 Skeletal muscle atrophy Muscle degeneration Muscle wasting [ more ] 0003202 Stenosis of the medullary [rarediseases.info.nih.gov]

[…] osteosclerosis Uneven increase in bone density 0005686 Pathologic fracture Spontaneous fracture 0002756 Presenile cataracts 0007819 Progressive Worsens with time 0003676 Proximal [rarediseases.info.nih.gov]

Juvenile GM2-Gangliosidosis

Progressive proximal muscle wasting, leg weakness, and fasciculations may be noted. [emedicine.medscape.com]

Behavioral or psychiatric problems, proximal and distal weakness, and muscle wasting also tended to appear late in the disease course. [ncbi.nlm.nih.gov]

muscle wasting, cramping, and weakness; and/or fasciculations. [emedicine.medscape.com]

ACTH-Independent Cushing Syndrome

Proximal muscle wasting and weakness. Diabetes or impaired glucose tolerance. Gonadal dysfunction, reduced libido. Hypertension. Nephrolithiasis. [patient.info]

muscle wasting (protein tissue wasting), osteopenia or osteoporosis, hypokalemia, mental changes and memory loss, depression, renal calculi, increased susceptibility to infection [physio-pedia.com]

Other physical examination findings in Cushing’s syndrome include facial plethora and proximal muscle weakness and wasting. [dermatologyadvisor.com]

Myopathy, Endocrine

muscle wasting and weakness. [ijem.in]

Hyperparathyroidism: Muscle wasting and myopathy (ie, proximal muscle weakness) are common. [forums.prohealth.com]

muscle wasting and weakness. [1] Severe muscle weakness is found in 2.4% to 21% of patients with exogenous glucocorticoid administration. [15] Actual incidence of steroid-induced [ijem.in]

Pituicytoma

A physical examination revealed features of hypopituitarism and hypogonadism, including central adiposity, nipple pallor, proximal muscle wasting, preservation of scalp hair [nejm.org]

Physical Exam Shows features of hypopituitarism and hypogonadism, including central adiposity, nipple pallor, proximal muscle wasting, preservation of scalp hair, loss of [slideplayer.com]

GM2-Gangliosidosis Types B - B1 - Ab

Progressive proximal muscle wasting, leg weakness, and fasciculations may be noted. [emedicine.medscape.com]

muscle wasting, cramping, and weakness; and/or fasciculations. [emedicine.medscape.com]

[…] lead to lack of coordination; hand tremors; progressive dystonia; dysarthria, dyskinesia; choreoathetosis; ataxia; spinocerebellar degeneration; motor neuron disease with proximal [emedicine.medscape.com]

Muscular Dystrophy-Dystroglycanopathy Type C4

muscle atrophy 0008988 Proximal amyotrophy Wasting of muscles near the body 0007126 Scapular winging Winged shoulder blade 0003691 Shoulder girdle muscle atrophy Shoulder [rarediseases.info.nih.gov]

[…] of proximal limb and axial muscles. [ng.neurology.org]

A term used for a GROUP of rare neuromuscular diseases which are inherited and known to cause muscle weakness & wasting. [lgmd-info.org]

Limb-Girdle Muscular Dystrophy Type 2E

Individuals with Limb-Girdle Muscular Dystrophy have a wasting and weakness of proximal muscles. [evolvegene.com]

A term used for a GROUP of rare neuromuscular diseases which are inherited and known to cause muscle weakness & wasting. [lgmd-info.org]

Charcot-Marie-Tooth Disease Type 4C

• Proximal muscle weakness and wasting may be the predominant feature in CMT4C. • Special respiratory care should be given for patients with CMT4C. [nmd-journal.com]

muscle wasting associated with dropped head syndrome. [nmd-journal.com]

Keywords Charcot–Marie–Tooth disease type 4C Dropped head syndrome CMT Proximal muscle weakness CMT4C To read this article in full you will need to make a payment References [nmd-journal.com]

Sarcotubular Myopathy

muscle weakness and wasting of the pelvic and shoulder girdles with onset that usually occurs during the second or third decade of life. [orpha.net]

Both had lower limb proximal muscle weakness with foot drop, severe wasting of tibialis anterior with a high-stepping gait. [neurologyindia.com]

Nalini et al. [78] identified two such patients who had lower-limb proximal muscle weakness with foot drop, severe wasting of tibialis anterior. [annalsofian.org]

Muscular Dystrophy-Dystroglycanopathy Type C14

[…] inflammation 0100614 Proximal amyotrophy Wasting of muscles near the body 0007126 Showing of 27 | Last updated: 5/1/2019 Making a diagnosis for a genetic or rare disease [rarediseases.info.nih.gov]

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the hips and shoulders (the pelvic and shoulder girdles). [icd10data.com]

Muscle weakness and wasting of the proximal and pelvic girdle muscles are the typical features of LGMD. [mdsa.co.za]

Muscular Dystrophy-Dystroglycanopathy Type C3

[…] and characterised by predominant weakness and wasting in proximal limb and axial muscles. [els.net]

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the hips and shoulders (the pelvic and shoulder girdles). [icd10data.com]

Muscular Dystrophy-Dystroglycanopathy Type C9

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the hips and shoulders (the pelvic and shoulder girdles). [icd10data.com]

Muscle weakness and wasting of the proximal and pelvic girdle muscles are the typical features of LGMD. [mdsa.co.za]

Limb-Girdle Muscular Dystrophy Type 1E

[…] and characterised by predominant weakness and wasting in proximal limb and axial muscles. [els.net]

A term used for a GROUP of rare neuromuscular diseases which are inherited and known to cause muscle weakness & wasting. [lgmd-info.org]

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the hips and shoulders (the pelvic and shoulder girdles). [icd10data.com]

Ehlers-Danlos Syndrome Classic-Like Type 2

[…] fiber splitting 0003555 Precocious atherosclerosis 0004416 Proximal amyotrophy Wasting of muscles near the body 0007126 Spina bifida occulta 0003298 Stroke 0001297 Percent [rarediseases.info.nih.gov]

[…] pain [ more ] 0003326 Proximal muscle weakness Weakness in muscles of upper arms and upper legs 0003701 Sensory neuropathy Damage to nerves that sense feeling 0000763 Skeletal [rarediseases.info.nih.gov]

[…] muscle atrophy Muscle degeneration Muscle wasting [ more ] 0003202 Thin skin 0000963 5%-29% of people have these symptoms Adrenal hypoplasia Small adrenal glands 0000835 [rarediseases.info.nih.gov]

Limb-Girdle Muscular Dystrophy Type 2L

[…] and characterised by predominant weakness and wasting in proximal limb and axial muscles. [els.net]

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the hips and shoulders (the pelvic and shoulder girdles). [icd10data.com]

Miyoshi Myopathy Type 1

[…] pain Muscle pain on exercise Muscle pain with exercise Muscle pain, exercise-induced [ more ] 0003738 Pelvic girdle muscle weakness 0003749 Proximal amyotrophy Wasting of [rarediseases.info.nih.gov]

muscles near the body 0007126 Quadriceps muscle weakness Quadriceps weakness 0003731 Shoulder girdle muscle weakness Weak shoulder muscles 0003547 Tibialis atrophy 0011399 [rarediseases.info.nih.gov]

Difficulty standing Difficulty in standing 0003698 Difficulty walking Difficulty in walking 0002355 Distal upper limb amyotrophy 0007149 Exercise-induced myalgia Exercise-induced muscle [rarediseases.info.nih.gov]

Hereditary Sensory and Autonomic Neuropathy Type 6

After age 20 years, the distal wasting and weakness may involve proximal muscles, possibly leading to wheelchair dependency by the seventh or eighth decade. [ncbi.nlm.nih.gov]

Weakness commences in the distal lower limbs, followed by the distal upper limbs and in severe cases, proximal upper- and lower-limb girdle muscles. [ncbi.nlm.nih.gov]

Distal muscle weakness and wasting are present in all advanced cases. The weakness of ankle flexors produces a floppy, flipper-like foot rather than pes cavus. [ncbi.nlm.nih.gov]

GM2 Gangliosidosis Variant AB

Progressive proximal muscle wasting, leg weakness, and fasciculations may be noted. [emedicine.com]

muscle wasting, cramping, and weakness; and/or fasciculations. [emedicine.com]

Congenital Muscular Dystrophy due to LMNA Mutation

Clinical examination revealed proximal muscle wasting and weakness. No heart involvement was present and death occurred at the age of 68 years for respiratory failure. [ncbi.nlm.nih.gov]

Remarkably, muscle weakness and wasting affected predominantly axial muscles as well as proximal upper and distal lower extremities. [deepdyve.com]

Patients typically presented with selective axial weakness and wasting of the cervicoaxial muscles. [ncbi.nlm.nih.gov]

Limb-Girdle Muscular Dystrophy Type 2G

By the age of 10 he had progressive generalized wasting and lower limb proximal muscle weakness. [journals.plos.org]

[…] and characterised by predominant weakness and wasting in proximal limb and axial muscles. [els.net]

Patients generally present with slowly progressive weakness and wasting restricted to the proximal muscles. [chs-journal.com]

Limb-Girdle Muscular Dystrophy Type 2J

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the hips and shoulders (the pelvic and shoulder girdles). [icd10data.com]

Muscle weakness and wasting of the proximal and pelvic girdle muscles are the typical features of LGMD. [mdsa.co.za]

Limb-Girdle Muscular Dystrophy Type 2A

Individuals with Limb-Girdle Muscular Dystrophy have a wasting and weakness of proximal muscles. [evolvegene.com]

[…] and characterised by predominant weakness and wasting in proximal limb and axial muscles. [els.net]

Limb-Girdle Muscular Dystrophy Type 2Q

The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the hips and shoulders (the pelvic and shoulder girdles). [icd10data.com]

Patients generally present with slowly progressive weakness and wasting restricted to the proximal muscles. [chs-journal.com]