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1,455 Possible Causes for Proximal Muscle Weakness

  • Acromegaly

    Although there is a lack of systematic studies on muscle function, it is believed that patients with acromegaly may suffer from proximal muscle weakness despite their increased[] Patients with acromegaly have decreased body fat (BF) and increased extracellular water (ECW) and muscle mass.[]

  • Oculopharyngeal Muscular Dystrophy

    Oculopharyngeal muscular dystrophy (OPMD) is typically inherited in an autosomal dominant fashion and is characterized by late onset proximal muscle weakness, ptosis and difficulty[] weakness.[] We describe a 70-year-old Italian woman with an adult-onset ptosis, mild dysphagia and proximal muscle weakness belonging to a family segregating OPMD according to an autosomal[]

  • Vitamin D Deficiency

    We report a four-year-old African boy referred for proximal muscle weakness, fatigability and episodic limb pain.[] A young woman with severe vitamin D deficiency presented with proximal muscle weakness, fragility fracture and pseudoarthrosis.[] All had generalized bone pain and tenderness, muscle weakness, stooping posture, difficulty walking, and waddling gait due to severe proximal muscle weakness for a period[]

  • Limb-Girdle Muscular Dystrophy

    Progressive proximal muscle weakness began again at age 8 years. Serum CK was 14,910 IU/L. She was wheelchair-bound by age 12.[] Moreover, polymyositis (PM) is manifested as symmetrical proximal muscle weakness of the four limbs, accompanied by an increased level of serum CK.[] This is a 39-year-old man who had slowly progressive proximal muscle weakness and cardiac arrhythmia since adolescent and a family history of similar manifestation.[]

  • Autosomal Recessive Progressive External Ophthalmoplegia

    PEOB3 patients manifest adult-onset progressive external ophthalmoplegia and progressive proximal muscle weakness associated with muscle atrophy.[] Methods: Samples from a large Pakistani family with adPEO, in which clinical symptoms are bilateral ptosis, limitations of eye movements, and varying degrees of proximal muscle[] weakness Ophthalmoparesis Elevated serum creatine phosphokinase Dysarthria Rare Symptoms - Less than 30% cases Increased serum lactate Slow progression Proximal muscle weakness[]

  • Multicore Myopathy

    Multicore myopathy, classified with the benign congenital myopathies, is manifest clinically as proximal muscle weakness, hypotonia, and delayed motor development.[] It is marked by hypotonia and proximal muscle weakness.[] muscle weakness ; Ptosis ; Pulmonary hypoplasia ; Recurrent respiratory infections ; Respiratory insufficiency ; Scoliosis ; Skeletal muscle atrophy ; Type 1 and type 2 muscle[]

  • X-Linked Hypophosphatemia

    muscle weakness for 8 years.[] 25 July 2017 Published 7 August 2017 calcium and bone radiology Description A 42-year-old man presented with lower limb bowing since childhood along with low backache and proximal[]

  • Childhood Dermatomyositis

    A 62-year-old woman presented to the emergency department with malaise, lethargy and proximal muscle weakness. She had a similar presentation in childhood.[] He considers that this may be dermatomyositis and tests for proximal muscle weakness.[] […] and skin, marked by proximal muscle weakness and a characteristic skin rash.[]

  • Dermatomyositis

    Later she developed progressive, symmetrical proximal muscle weakness.[] The proximal muscle weakness, dysphagia and presence of Gottron's papules as well poikiloderma like skin changes led to the clinical diagnosis of dermatomyositis.[] The patient presented with proximal muscle weakness, rash, elevated muscle enzyme, myopathic electromyograph and typical muscle biopsy.[]

  • Cushing's Disease

    The following signs and symptoms are common: Weight gain Skin changes Hirsutism Menstrual disorders Progressive proximal muscle weakness Infertility Impotence Moodiness, irritability[] Muscle weakness. In particular a proximal muscle weakness. The proximal muscles are the ones in your arms and legs nearest to the body.[] Common symptoms include weight gain, skin changes, hyperhidrosis, infertility, hirsutism, amenorrhea, muscle weakness and psychological problems.[]

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