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150 Possible Causes for Pruritic Rash, Sore Mouth, T Cell Activation Increased

  • Hypersensitivity

    However, increased activation of CD4 T-cell and CD8 T-cells was only observed following four days of DDAB exposure.[ncbi.nlm.nih.gov] These sores can be found on the genitals, vagina, anus, rectum, lips and mouth. Pregnant women can transmit the disease to their unborn child.[niaid.nih.gov] rash.[ncbi.nlm.nih.gov]

  • Food Allergy

    Memory T cells are increased in frequency and have distinct activation requirements and cell-surface proteins that distinguish them from armed effector T cells 10-25.[ncbi.nlm.nih.gov] […] defects of permanent teeth Adults are less likely to have digestive signs and symptoms and may instead have one or more of the following: anemia bone or joint pain canker sores[web.archive.org] It is a blistering skin disorder that manifests clinically with a chronic and intensely pruritic rash with a symmetrical distribution.[emedicine.com]

  • Celiac Disease

    APC presents the toxic peptide to CD4 T cells. Activated gluten-reactive CD4 T-cells produce high levels of pro-inflammatory cytokines.[doi.org] […] problems such a canker sores or dry mouth seizures tingling numbness in the hands and feet tiredness weak and brittle bones Adults who have digestive symptoms with celiac[web.archive.org] About 10% of patients have dermatitis herpetiformis , an intensely pruritic papulovesicular rash that is symmetrically distributed over the extensor areas of the elbows, knees[merckmanuals.com]

  • Mercury Poisoning

    While the lymph cell proliferation response against T cell and B cell mitogen increased in the thymus and spleen, NK cell activation was reduced by 44% in the spleen, and[doi.org] […] teeth excessive salivation foul breath metallic taste burning sensation, with tingling of lips, face tissue pigmentation (amalgam tattoo of gums) leukoplakia stomatitis (sores[mercurypoisoned.com] To assess the activation of the immune system, the expression of HLA-DR on both CD4 and CD8 T-cell subsets was also analyzed.[frontiersin.org]

  • Lichen Planus

    […] an increase in Th1 and Th17 subtypes cells, triggered by the release of cytokines.[ncbi.nlm.nih.gov] Oral lichen planus: On the gums, lichen planus can cause redness and sores.[aad.org] Lichen planus presents with the development of purple colored pruritic rash with flat tops.[symptoma.com]

  • Dermatitis

    These early effects lead to increased histamine release from IgE-activated mast cells and elevated activity of the T-helper cell–mediated immune system.[emedicine.com] Oral exposure may cause sore mouth (tongue) and rash of the lips or angles of the mouth. Am I allergic to Balsam of Peru?[web.archive.org] ., and Randy Tang, M.D. 4 Citing Articles A 31-year-old man presented with a 1-week history of pruritic rash on his left foot, which developed after he brushed against coral[nejm.org]

  • Contact Dermatitis

    Investigations of allergic contact dermatitis suggest that certain allergens may also activate particular T cell signatures such as TH 2-dominant responses to fragrance and[ncbi.nlm.nih.gov] Herpes Simplex/Cold Sores Herpes simplex can be either Type 1, which produces cold sores or fever blisters on the mouth, or Type 2, which is typically spread through sexual[dermrochester.com] Subacute forms of dermatitis present as less intense pruritic, erythematous, scaling and fissured skin rash.[podiatrytoday.com]

  • Infectious Mononucleosis

    The persistent activation of T cells in our patient may have increased the likelihood of development of uncontrolled T-cell lymphoproliferative disease.[dx.doi.org] Infectious mononucleosis is characterized by swollen lymph glands, fever, sore throat, and extreme fatigue.[hopkinsmedicine.org] Fine macular non-pruritic rash, which rapidly disappears. Transient bilateral upper lid oedema. Lymphadenopathy, especially neck glands. Nausea and anorexia.[patient.info]

  • Psoriasis

    The psoriatic lesions are linked with increased T-cell activity beneath the underlying skin area.[symptoma.com] […] loss, sun sensitivity, headaches, joint and muscle pain, hepatotoxicity, dyslipidemia, inhibition of bone growth Systemic methotrexate: gastrointestinal upsets, nausea, oral[clinicaladvisor.com] Pruritic urticarial papules and plaques of pregnancy. The rash presentation can vary; two examples are shown above.[aafp.org]

  • Graft-versus-Host-Disease

    T cells. 6, 7 Treated monocytes exhibit an activated phenotype with increased phagocytic and antigen presenting activity facilitating processing of apoptotic T cells leading[doi.org] […] in the mouth (stomatitis), nausea, severe bleeding (hemorrhage), low levels of red blood cells (anemia) and lung infection (pneumonia).[pharmacytimes.com] Acute graft-versus-host-disease usually presents within three to four weeks of transplantation with a painful, pruritic rash.[symptoma.com]

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