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127 Possible Causes for Pruritus, Spasticity - Hyperreflexia

  • Pregnancy

    A total of 31 of the 49 infants (63%) had grossly abnormal results on neurologic examinations; hypertonicity, clonus, hyperreflexia, abnormal movements, spasticity, contractures[nejm.org] Intrahepatic cholestasis typically occurs in late pregnancy, and it is characterized by intense pruritus and rash over the hands and feet.[emedicine.medscape.com] , hyperreflexia, contractures, dysphagia, and feeding difficulties.[nejm.org]

  • Sjögren-Larsson Syndrome

    Although all patients exhibited spastic paraparesis, they differed in their ability to ambulate.[jamanetwork.com] The findings reported here, point to a crucial role for leukotriene B4 in the pathogenesis of pruritus.[ncbi.nlm.nih.gov] Title: Zileuton for Pruritus in Sjogren-Larsson Syndrome: A Randomized Double-blind Placebo-controlled Crossover Trial Author(s): Fuijkschot, J. ; Seyger, M.M.B. ; Bastiaans[repository.ubn.ru.nl]

  • Cervical Spine Disease

    Upper motor neurone signs in the lower limbs (Babinski's sign - up-going plantar reflex, hyperreflexia, clonus, spasticity).[patient.info] BACKGROUND: The main cause of brachioradial pruritus (BRP) is not known but there is evidence to suggest that BRP may arise in the nervous system.[ncbi.nlm.nih.gov] Title Brachioradial pruritus: cervical spine disease and neurogenic/neuropathic pruritus UMMS Affiliation Department of Medicine, Division of Dermatology Publication Date[escholarship.umassmed.edu]

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[aafp.org] […] hypertension, hypoglycemia, hypomagnesia, hyponatremia, hypotension, insomnia, nausea, oral candidiasis, pain, peripheral edema, pharyngolaryngitis, phlebitis, pneumonia, polyuria, pruritus[aafp.org]

  • Infective Dermatitis Associated with HTLV-1

    HAM/TSP is characterized by progressive, permanent lower-extremity weakness, spasticity, hyperreflexia, sensory disturbances, and urinary incontinence (Table 2).[cdc.gov] It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus.[bioportfolio.com] In more than 90% of the cases, the neurological features involve: spasticity and/or hyperreflexia of the lower extremities, urinary bladder disturbance, lower extremity muscle[medcraveonline.com]

  • Microcephalic Primordial Dwarfism due to ZNF335 Deficiency

    Related symptoms: Autosomal recessive inheritance Generalized hypotonia Nystagmus Spasticity Hyperreflexia SOURCES: MESH GARD UMLS OMIM MONDO More info about AICARDI-GOUTIERES[mendelian.co] […] seizures Epileptic spasms Muscular hypotonia Death in infancy Peripheral neuropathy Talipes equinovarus Dysphagia Developmental stagnation Hypoventilation Poor eye contact Pruritus[mendelian.co] Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS.[ncbi.nlm.nih.gov]

  • Hepatosplenomegaly

    Systemic Features: Infants with type I disease are usually hypotonic from birth but develop spasticity, psychomotor retardation, and hyperreflexia within 6 months.[disorders.eyes.arizona.edu] Amyloidosis may be associated not only with Hepatolienal syndrome, but also, more rarely, with the advent of cholestatic jaundice and pruritus,.[authorstream.com] Gaucher’s disease History in hepatosplenomegaly Presenting complaint Abdominal swelling History of presenting complaint Abdominal pain Bloating Abnormal bruising/bleeding Pruritus[oxfordmedicaleducation.com]

  • Multifocal Motor Neuropathy

    Upper motor neuron signs (spasticity, hyperreflexia, extensor plantar response).[clinicaltrials.gov] Immunodeficiency, Immunoglobulin, Infectious Diseases, Kidney Disease, Meningitis, Migraine, Muscle, Nausea, Neurology, Neuromuscular Disease, Neuropathy, Obesity, Pain, Placebo, Pruritus[news-medical.net] Atrophy may be present, but hyperreflexia and spasticity are not seen.[ncbi.nlm.nih.gov]

  • Palmoplantar Keratosis

    Nevus Epicanthus Visual impairment Spasticity Cleft palate Gait disturbance Ptosis Strabismus Nystagmus Lobular carcinoma in situ Merkel cell skin cancer Ductal carcinoma[mendelian.co] […] accentuated with immersion in water. 7 Most patients with KPPP are asymptomatic and are often diagnosed incidentally on examination; however, in some cases, symptoms of burning, pruritus[mdedge.com] […] palmoplantar keratoderma (APPK), also known as aquagenic wrinkling of the palms, is characterized by oedema of palms and/or soles, whitish papules, hyperwrinkling and sometimes pruritus[ncbi.nlm.nih.gov]

  • Generalized Clonic or Tonic-Clonic Seizures

    Seizures Milia Spasticity Hyperreflexia SOURCES: DOID GARD OMIM MESH MONDO ORPHANET UMLS More info about SPASTIC PARAPLEGIA 6, AUTOSOMAL DOMINANT; SPG6 Low match EPILEPTIC[mendelian.co] […] cortical atrophy Absent speech Dyskinesia Hypsarrhythmia CNS hypomyelination Neonatal onset Apraxia Postural instability Cerebral hypomyelination Olivopontocerebellar atrophy Pruritus[mendelian.co] […] with hyperreflexia and extensor plantar responses, as well as mild bladder disturbances and pes cavus.[mendelian.co]

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