Possible Causes for psammomatous melanotic schwannomas Carney Complex We present a case of psammomatous melanotic schwannoma as part of Carney complex in a 67-year-old male. [ncbi.nlm.nih.gov] Histopathologic examination revealed the diagnosis of a malignant psammomatous melanotic schwannoma that is associated with the Carney complex in 50% of these patients. [ncbi.nlm.nih.gov] Psammomatous melanotic schwannoma as a component of Carney complex. [ijpmonline.org] Carney-Stratakis Syndrome Carney: Psammomatous melanotic schwannoma. A distinctive inheritable tumor with special associations, including cardiac myxoma and endocrine overactivity. [whonamedit.com] melanotic schwannoma ( Am J Surg Pathol 1991;15:722 ) Ductal adenoma: palpable painless mass near the areola Myxomas occur in heart but can also occur on the skin (eyelid [pathologyoutlines.com] The psammomatous melanotic schwannomas are typically benign; they metastasize, however, in as many as 10% of cases. [emedicine.medscape.com] Primary Pigmented Nodular Adrenocortical Disease melanotic schwannomas (5%); also neurofibromatosis, cerebral hemangioma]; associated with 2p16 abnormalities Sporadic and non-familial patients are usually infants or age [pathologyoutlines.com] OR10–3, 1995; 59. 5 Carney JA. 1990 Psammomatous melanotic schwannoma. [academic.oup.com] The psammomatous melanotic schwannomas are typically benign; they metastasize, however, in as many as 10% of cases. [emedicine.medscape.com] Carney Triad melanotic schwannoma testicular tumors Sertoli cell tumors : most common Pathology Carney complex has autosomal dominant inheritance related to mutation of the PRKAR1A tumor [radiopaedia.org] Carney: Psammomatous melanotic schwannoma. A distinctive inheritable tumor with special associations, including cardiac myxoma and endocrine overactivity. [whonamedit.com] […] also well recognized including: extracardiac myxoma breast testis thyroid brain adrenal gland: primary pigmented nodular adrenocortical disease (PPNAD) pituitary adenoma psammomatous [radiopaedia.org] Blue Nevus melanotic schwannoma. [histopathology-india.net] A multicentric familial tumor with important associations, including cardiac myxoma and psammomatous melanotic schwannoma. Am J Surg Pathol 1996;20:259-72. [jomfp.in] Psammomatous melanotic schwannoma. A distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome. [emedicine.medscape.com] Sertoli Cell Tumor of the Testis melanotic schwannoma, blue nevus, ductal adenoma of breast, and osteochondromyxoma. [jpatholtm.org] melanotic schwannoma. [path.upmc.edu] […] mucosal myxoma, myxomatosis of the breast, primary pigmented nodular adrenocortical disease, acromegaly with growth hormone-producing adenoma, LCCSCT, thyroid carcinoma, psammomatous [jpatholtm.org] Neurilemmoma In psammomatous melanotic schwannoma, varying numbers of psammoma bodies are present. [histopathology-india.net] [8] and a variant with a plexiform multinodular pattern. [9] Other variants are associated with genetic syndromes such as Carney complex (ie, psammomatous melanotic schwannoma [emedicine.medscape.com] Characteristic findings on physical examination Psammomatous melanotic shwannomas are a part of Carney complex. Schwannomas present as slow-growing tumors. [clinicaladvisor.com] Spindle Cell Sarcoma of the Duodenum Psammomatous melanotic schwannoma. A distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome. [nature.com] In general, most psammomatous melanotic schwannomas behave indolently, but rare extraintestinal examples have had a more aggressive clinical course. 27 It is unclear if the [nature.com] Figure 5 Psammomatous melanotic schwannoma. ( a ) The tumor is seen here occupying the mucosa and submucosa and is composed of bland spindle to polygonal plump, bland cells [nature.com] Clear Cell Sarcoma melanotic schwannoma, and metastatic MM.[ 7 ] The distinction between CCS and MM should be done [ Table 1 ]. [ncbi.nlm.nih.gov] […] melanocytic tumor, clear cell myomelanocytic tumor, malignant peripheral nerve sheath tumor, monophasic synovial sarcoma, deep-seated epithelioid sarcoma, adult fibrosarcoma, psammomatous [ncbi.nlm.nih.gov] Congenital Non-Neoplastic Nevus Epithelioid blue nevus and psammomatous melanotic schwannoma: the unusual pigmented skin tumors of the Carney complex. Semin Diagn Pathol 1998 ; 15 ( 3 ): 216–24. 48. [cambridge.org] Juvenile Nevus Epithelioid blue nevus and psammomatous melanotic schwannoma: the unusual pigmented skin tumors of the Carney complex. Semin Diagn Pathol 1998 ; 15 ( 3 ): 216–24. 48. [cambridge.org] Benign Lipomatous Neoplasm Psammomatous melanotic schwannoma: a distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome. [nejm.org] […] pituitary gland tumour schwannoma (neurilemmoma), peripheral nerve schwannoma of the bone schwannoma, psammomatous melanotic schwannomas of the (posterior) spinal nerve roots [hccpjournal.biomedcentral.com] Epithelioid blue nevus and psammomatous melanotic schwannoma: The unusual pigmented skin tumors of the Carney complex. Semin Diagn Pathol 1998; 15: 216-224. 2. [hccpjournal.biomedcentral.com] Cardiac Myxoma melanotic schwannomas, vi) primary pigmented nodular adrenocortical disease (including patients symptomatic with Cushing syndrome), vii) testicular tumours (bilateral, multicentric [histopathology-india.net] […] single or multiple) iii) mammary myxoid fibroadenomas (single or multiple) iv) spotty mucocutaneous pigmentation (including lentigines and blue nevi and combinations) v) psammomatous [histopathology-india.net] Zosteriform Lentiginosis Carney, J.A.: Psammomatous melanotic schwannoma. A distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome. [bioscience.org] A multicentric familial tumor with important associations, including cardiac myxoma and psammomatous melanotic schwannoma. Am J Surg Pathol 20, 259-272 (1996) 28. [bioscience.org] In addition, three new components of the syndrome have been identified: psammomatous melanotic schwannoma, epithelioid blue nevus, and ductal adenoma of the breast (26, 37 [bioscience.org] Ganglioneuroma Psammomatous melanotic Schwannoma: a distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome. [ajnr.org] Carney Complex Type 1 melanotic schwannoma (PMS). [kjim.org] Malignant psammomatous melanotic schwannoma of the spine: A component of Carney complex. [surgicalneurologyint.com] Histopathology: The soft tissue schwannomas are a very unusual variant known as psammomatous melanotic schwannoma. [dermatologyadvisor.com] Pituitary Adenoma The psammomatous melanotic schwannomas are typically benign; they metastasize, however, in as many as 10% of cases. [emedicine.medscape.com] Nonmyxomatous tumors, such as pituitary adenomas, psammomatous melanotic schwannomas, and Sertoli cell tumors of the testis, also may be observed. [emedicine.medscape.com] These tumors include myxomas of the skin, heart, breast, and other sites; primary pigmented nodular adrenocortical disease, psammomatous melanotic schwannomas; growth hormone–producing [emedicine.medscape.com] Primary Cardiac Sarcoma melanotic schwannoma, breast ductal adenoma, and osteochondromyxoma. [merckmanuals.com] […] adrenocortical disease causing Cushing syndrome, growth hormone and prolactin-producing pituitary adenoma, testicular tumors, thyroid adenoma or carcinoma, and ovarian cysts), psammomatous [merckmanuals.com] Suprasellar Tumor MPNST Melanotic psammomatous MPNST Melanotic schwannoma Plexiform schwannoma Cellular schwannoma Degenerated schwannoma Ancient schwannoma Psammomatous schwannoma Malignant [doczz.net] […] neuroma (C72.4) Pigmented schwannoma Melanotic schwannoma Plexiform schwannoma Cellular schwannoma Degenerated schwannoma Ancient schwannoma Psammomatous schwannoma 9560/ [doczz.net] MPNST Melanotic psammomatous MPNST 9541/0 Melanotic neurofibroma 9550/0 Plexiform neurofibroma Plexiform neuroma 9560/0 Neurilemoma, NOS Schwannoma, NOS Neurinoma Acoustic [doczz.net] Pulmonary Hemangioma […] of tumor cells show the substructure of neurilemmoma; and melanotic psammomatous schwannoma, exhibiting microcalcifications and melanin pigmentation 118 ( Fig. 19-36 ). [clinicalgate.com] “ancient” schwannoma, showing scattered pleomorphic hyperchromatic nuclei in degenerative cells ( Fig. 19-35 ); plexiform schwannoma, in which broad plexiform fascicles [clinicalgate.com] […] schwannoma, which manifests intersecting bundles of densely apposed, focally mitotic spindle cells in the context of an encapsulated mass 111 ( Fig. 19-34 ); “glandular” schwannoma [clinicalgate.com] Angiocentric Glioma Psammomatous melanotic schwannomas may be multiple. [epdf.pub] […] versus non-psammomatous melanotic schwannomas, 187 Pseudopalisading necrosis, 81, 283 Pseudotumor, inflammatory, 252 PTCH1 gene, 158 PTEN gene, 109 PTLDs. [epdf.pub] In contrast, non-psammomatous melanotic schwannomas are usually single lesions, not associated with neurofibromatosis, type II, or any other tumor predisposition syndrome. [epdf.pub] Cardiac Metastasis melanotic schwannoma, breast ductal adenoma, and osteochondromyxoma. [msdmanuals.com] […] adrenocortical disease causing Cushing syndrome, growth hormone and prolactin-producing pituitary adenoma, testicular tumors, thyroid adenoma or carcinoma, and ovarian cysts), psammomatous [msdmanuals.com] Lamellar Ichthyosis melanotic schwannomas psammomatous melanotic schwannomas multiple fractures thin skin blue sclera MVP** Osteogenesis Imperfecta Type 1 Osteogenesis Imperfecta Type II Osteogenesis [brainscape.com] melanotic schwannomas name the findings in LAMB/NAME/Carney complex Lentigenes Atrial Myxoma Mucocutaneous myxomas Blue nevi Nevi Atrial myxomas Myxoid tumors Ephelids psammomatous [brainscape.com] Ferguson Smith, *also found in Muire Torre Syndrome cutaneous myxomas areola myxomas atrial myxomas Cushings syndrome from primary pigmented nodular adrenocortical disease psammomatous [brainscape.com] Primary Pigmented Nodular Adrenocortical Disease 4 […] pituitary gland tumor schwannoma (neurilemmoma), peripheral nerve schwannoma of the bone schwannoma, psammomatous melanotic schwannomas of the (posterior) spinal nerve roots [familialcancerdatabase.nl] melanotic schwannomas (5%); also neurofibromatosis, cerebral hemangioma]; associated with 2p16 abnormalities Sporadic and non-familial patients are usually infants or age [pathologyoutlines.com] The psammomatous melanotic schwannomas are typically benign; they metastasize, however, in as many as 10% of cases. [emedicine.medscape.com] Primary Pigmented Nodular Adrenocortical Disease 1 […] pituitary gland tumor schwannoma (neurilemmoma), peripheral nerve schwannoma of the bone schwannoma, psammomatous melanotic schwannomas of the (posterior) spinal nerve roots [familialcancerdatabase.nl] melanotic schwannomas (5%); also neurofibromatosis, cerebral hemangioma]; associated with 2p16 abnormalities Sporadic and non-familial patients are usually infants or age [pathologyoutlines.com] The psammomatous melanotic schwannomas are typically benign; they metastasize, however, in as many as 10% of cases. [emedicine.medscape.com] Pleural Neurilemmoma benign myxoid schwannoma, benign epithelioid schwannoma, benign glandular schwannoma, and psammomatous melanotic schwannoma.[2] Case Report A 60-year-old woman presented [digitmedicine.com] […] such as leiomyoma, leiomyosarcoma, and calcifying aponeurotic fibroma which may also show palisading of the nuclei.[2] Histopathological variants of this lesion are ancient schwannoma [digitmedicine.com] Acoustic Neuroma Select ICD-O code and name: 9560/0 Neurilemoma, NOS 9560/0 Schwannoma, NOS 9560/0 Neurinoma 9560/0 Acoustic neuroma 9560/0 Pigmented schwannoma 9560/0 Melanotic schwannoma [codes.iarc.fr] 9560/0 Plexiform schwannoma 9560/0 Cellular schwannoma 9560/0 Degenerated schwannoma 9560/0 Ancient schwannoma 9560/0 Psammomatous schwannoma [codes.iarc.fr] Familial Atrial Myxoma […] pituitary gland tumor schwannoma (neurilemmoma), peripheral nerve schwannoma of the bone schwannoma, psammomatous melanotic schwannomas of the (posterior) spinal nerve roots [familialcancerdatabase.nl] Although rare, cancerous tumors may occur in Carney complex including thyroid carcinoma and malignant psammomatous melanotic schwannoma. [rarediseases.org] melanotic schwannomas, vi) primary pigmented nodular adrenocortical disease (including patients symptomatic with Cushing syndrome), vii) testicular tumours (bilateral, multicentric [histopathology-india.net] Pheochromocytoma-Islet Cell Tumor Syndrome Nonendocrine tumors include psammomatous melanotic schwannoma, epithelioid blue nevus, and ductal adenoma of the breast. [doctorlib.info] For psammomatous melanotic schwannoma, magnetic resonance imaging of the brain, spine, chest, abdomen, retroperitoneum, or pelvis may be necessary. [doctorlib.info] Adrenocortical Hyperplasia melanotic schwannoma, epithelioid blue nevus, and ductal adenoma of the breast and thyroid follicular neoplasms, both benign and malignant (15). [scielo.br] […] pituitary adenomas and acromegaly, large-cell calcifying Sertoli cell tumors (among the rarest of testicular neoplasms), adrenocortical lesions, and Leydig cell tumors, psammomatous [scielo.br]
