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21 Possible Causes for Pseudohypertrophy of Calf Muscles, Vertebral Fractures

  • Duchenne Muscular Dystrophy

    We describe the case of a 20-year-old boy with DMD suffering from back pain due to multiple vertebral fractures who was treated with teriparatide.[ncbi.nlm.nih.gov] Early signs may include pseudohypertrophy (enlargement of calf muscles), low endurance, and difficulties in standing unaided or inability to ascend staircases.[disabled-world.com] Clinical examination reveals muscle pseudohypertrophy affecting the calf muscles and there may be atrophy of more proximal muscles such as the quadriceps.[orpha.net]

  • Muscular Dystrophy

    Vertebral Fractures in Duchenne Muscular Dystrophy Patients Managed With Deflazacort. J Pediatr Orthop. 2018 Jul. 38 (6):320-324. [Medline].[emedicine.medscape.com] Pseudohypertrophy of the calf muscles is due to fibrous tissue and fat infiltration. Involvement of the heart consists of usually terminal cardiomyopathy.[icd9data.com] Calf muscles initially enlarge and the enlarged muscle tissue is eventually replaced with fat and connective tissue (pseudohypertrophy).[genome.gov]

  • Becker Muscular Dystrophy

    fractures: High frequency; Up to 100% by 9 years Short stature 27 ?[neuromuscular.wustl.edu] , fatigue and pseudohypertrophy of calf muscles[medical-dictionary.thefreedictionary.com] fractures. [17] Other bone mass—enhancing drugs may be worthy of further investigation, but research is lacking in this area.[emedicine.medscape.com]

  • Spinal Muscular Atrophy

    Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastases. J Neurosurg Spine. 2012 Jan 6. [Medline].[emedicine.medscape.com] Radiofrequency heat ablation and vertebroplasty in the treatment of neoplastic vertebral body fractures. Anticancer Res. 2004;24(5B):3129-3133. 13.[iolearning.com] Percutaneous balloon kyphoplasty in the treatment of pathological vertebral body fracture and deformity in multiple myeloma: a one-year follow-up.[scielo.br]

  • Hypothyroidism

    Risk factors for vertebral and nonvertebral fracture over 10 years: a population-based study in women. J Bone Miner Res. 2008;23(1):75-85.[jama.jamanetwork.com] At clinical examination, she presented with bradycardia, pale and round face, pseudohypertrophy of calf muscles and no pitting edema of the limbs.[ncbi.nlm.nih.gov] Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy.[web.archive.org]

  • Congenital Muscular Dystrophy

    Vertebral Fractures in Duchenne Muscular Dystrophy Patients Managed With Deflazacort. J Pediatr Orthop. 2018 Jul. 38 (6):320-324. [Medline].[emedicine.medscape.com] We report the first known Egyptian patient with FCMD, established by clinical features of generalized weakness, pseudohypertrophy of calf muscles, progressive joint contractures[ncbi.nlm.nih.gov] Muscle pseudohypertrophy (calves and tongue): dystroglycanopathies.[ncbi.nlm.nih.gov]

  • Emery-Dreifuss Muscular Dystrophy Type 1

    Vertebral Fractures in Duchenne Muscular Dystrophy Patients Managed With Deflazacort. J Pediatr Orthop. 2018 Jul. 38 (6):320-324. [Medline].[emedicine.medscape.com] Contractures of the elbow, flexors, neck flexors, and calf muscles often occur; muscle pseudohypertrophy and mental retardation do not occur. A cardiomyopathy is common.[medical-dictionary.thefreedictionary.com] Kids with MD often develop enlarged calf muscles (called calf pseudohypertrophy ) as muscle tissue is destroyed and replaced by fat. How Is Muscular Dystrophy Diagnosed?[kidshealth.org]

  • Neurological Disorder

    fractures, as well as biopsies of certain tumors.[hopkinsmedicine.org] […] childhood  Difficulty rising from squatting position (use hands to ‘climb’ up legs – Gowers’ sign)  Pseudohypertrophy of calf muscles (muscle replaced by fatty tissue) [slideshare.net] Bone anomalies may also be present and manifest as deformations, osteopenia, which sometimes leads to pathological fractures or vertebral compression, bone infarctions or[orpha.net]

  • Myopathy

    […] compression fractures.[ncbi.nlm.nih.gov] […] weakness Pseudohypertrophy of muscles Palpable muscle nodules MacroglossiaPeripheral neuropathy Autonomic involvement Restrictive cardiomyopathy Inherited Myopathies Duchenne[clevelandclinicmeded.com] Diffusely scattered myeloma lesions were shown as hyperintense on short tau inversion recovery (STIR) MRI imaging throughout the appendicular and axial skeleton, with vertebral[ncbi.nlm.nih.gov]

  • Facioscapulohumeral Muscular Dystrophy

    COMPLICATIONS: inappropriate positioning; there should be a 10 - 20 degree angle between vertebral border of scapula and the spine. rib and scapula fractures brachial plexus[gait.aidi.udel.edu] Pseudohypertrophy of the calf muscles is due to fibrous tissue and fat infiltration. Involvement of the heart consists of usually terminal cardiomyopathy.[icd9data.com] pseudohypertrophy LABS: CPK is usually normal histology: not impressive; most constant finding is isolated small atrophic fibers intermixed with hypertrophic muscle fibers[gait.aidi.udel.edu]

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