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17 Possible Causes for Psychiatric Manifestation, Supraclavicular Fat Pads

  • Cushing's Disease

    Endogenous hypercortisolism is associated with an increased risk of cardiovascular and metabolic manifestations, as well as respiratory disorders, psychiatric complications[ncbi.nlm.nih.gov] Weight gain in face ( moon face ) Weight gain above the collar bone (supraclavicular fat pad) Weight gain on the back of neck ( buffalo hump ) Skin changes with easy bruising[aans.org] View Article PubMed Google Scholar Jeffcoate WJ, Silverstone JT, Edwards CR, Besser GM: Psychiatric manifestations of Cushing's syndrome: response to lowering of plasma cortisol[ojrd.biomedcentral.com]

  • Iatrogenic Cushing's Disease

    manifestations such as depression and psychosis (Newell-Price et al. 2006 ).[springerplus.springeropen.com] Weight gain in face ( moon face ) Weight gain above the collar bone (supraclavicular fat pad) Weight gain on the back of neck ( buffalo hump ) Skin changes with easy bruising[aans.org] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com]

  • Adrenal Cortex Hormone

    Cortisol and its synthetic analogs have been in widespread clinical use for the treatment of a variety of disorders for more than 50 years. Since their first clinical application, intensive research has expanded our understanding of the physiology, biochemistry, and pharmacology of steroids and has led to a large[…][ncbi.nlm.nih.gov]

  • Cushing Syndrome

    There is an excellent review of the psychiatric manifestations of Cushing's syndrome, which are an often overlooked component of this disorder.[amazon.com] Features more specific to Cushing's syndrome include proximal muscle weakness, supraclavicular fat pads, facial plethora, violaceous striae, easy bruising, and premature osteoporosis[bestpractice.bmj.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org]

  • Ectopic ACTH Syndrome

    Clinical manifestations included Cushingoid features (100%), psychiatric symptoms (90%), hypertension (70%), diabetes/impaired glucose tolerance (40%), osteoporosis (10%),[ncbi.nlm.nih.gov] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com]

  • Obesity

    This may be a manifestation of obsessive behaviour secondary to some of the psychiatric features commonly seen in chromosome 22q11.2 deletion syndrome.[ncbi.nlm.nih.gov]

  • Mixed Functioning Pituitary Adenoma

    Psychiatric [ edit ] Various psychiatric manifestations have been associated with pituitary disorders including pituitary adenomas.[en.wikipedia.org] Cushing’s Disease • Moon facies • Facial plethora • Supraclavicular fat pads • Buffalo hump • Truncal obesity • Weight gain • Purple striae •Proximal muscle weakness •Easy[slideshare.net] Psychiatric manifestations may include depression, anxiety , easy irritability and emotional instability. It may also result in various cognitive difficulties.[en.wikipedia.org]

  • Cortisone

    Psychiatric side effects including euphoria, insomnia , mood swings, personality changes, severe depression , and psychotic manifestations have been reported. [ Ref ] Nervous[drugs.com] Cushing's syndrome invariably presents with a classical phenotype comprising central adiposity, prominence of dorsal, supraclavicular and temporal fat pads, bruising, abdominal[ncbi.nlm.nih.gov] […] osteoporosis , vertebral compression fractures, aseptic necrosis of femoral and humoral heads, pathologic fracture of long bones, and tendon rupture have been reported. [ Ref ] Psychiatric[drugs.com]

  • ACTH-Dependent Cushing Syndrome

    View Article PubMed Google Scholar Jeffcoate WJ, Silverstone JT, Edwards CR, Besser GM: Psychiatric manifestations of Cushing's syndrome: response to lowering of plasma cortisol[ojrd.biomedcentral.com] Case: A 26-year-old male patient presented with moon face, purplish striae, supraclavicular fat pads and proximal muscle weakness.[endocrine-abstracts.org] Hypertension, glucose intolerance, osteoporosis and psychiatric symptoms generally improve, but may not resolve completely.[clinicaladvisor.com]

  • ACTH-Independent Cushing Syndrome

    Hypertension, glucose intolerance, osteoporosis and psychiatric symptoms generally improve, but may not resolve completely.[clinicaladvisor.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com]

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