We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…] [ncbi.nlm.nih.gov]
Psychiatric manifestations of multiple sclerosis: A review. Can J Psychiatry 1996 ; 41: 441 – 445. Google Scholar SAGE Journals ISI 5. Patten, SB, Svenson, LW, Metz, LM. [dx.doi.org]
Fatigue and psychiatric symptoms, such as depression or euphoria, can also be manifestations of MS. Symptoms (attacks) of MS need disseminated in “time and space.” [clinicaladvisor.com]
Huntington's disease (HD) is an autosomal dominant and progressive neurodegenerative syndrome characterized by motor, cognitive and psychiatric manifestations. [ncbi.nlm.nih.gov]
Although noncompliance to oral antipsychotic drugs can be a practical problem, especially when significant psychiatric manifestations of HD are present, the effect of depot [ncbi.nlm.nih.gov]
To our knowledge, this is the first case report on combat related PTSD as psychiatric disorder manifested prior to HD. [ncbi.nlm.nih.gov]
myelopathy, ataxia and psychiatric manifestations. [ncbi.nlm.nih.gov]
In our case after the confirmation of possible CNS WD (fever of unknown origin, chronic migratory arthralgias, unexplained lymphadenopathy, supranuclear vertical gaze palsy [benthamopen.com]
Patients with central nervous system (CNS) involvement may present in a variety of ways, including cognitive impairment, psychiatric manifestations, gaze palsies, upper motor [link.springer.com]
Individuals have been described in the medical literature with other psychiatric manifestations such as obsessive-compulsive disorder, bipolar disorders, and hallucinations [rarediseases.org]
Vertical gaze palsy (the inability to move the eyes up and down), enlarged liver, enlarged spleen, or jaundice in young children are strong indications that NPC should be [nnpdf.org]
Vertical supranuclear gaze palsy may be present. [patient.info]
Psychiatric manifestations may remain isolated for several years. [dx.doi.org]
Alongside psychiatric disorders, patients develop early motor signs: ataxia, abnormal movements and, an almost consistent finding, vertical supranuclear gaze palsy. [ncbi.nlm.nih.gov]
This review focuses on neurologic and psychiatric manifestations implicated with gluten sensitivity, reviews the emergence of gluten sensitivity distinct from celiac disease [dx.doi.org]
Patients with central nervous system (CNS) involvement may present in a variety of ways, including cognitive impairment, psychiatric manifestations, gaze palsies, upper motor [link.springer.com]
We describe a patient with cerebral Whipple disease who presented with changes in mental status, confusion, inverse sleep-wake cycle, bilateral ptosis and vertical gaze palsy [ncbi.nlm.nih.gov]
Patients may present in a variety of ways, including cognitive impairment, psychiatric manifestations, gaze palsies, upper motor neurone signs and hypothalamic dysfunction [jmedicalcasereports.com]
NP-C is characterised by visceral, neurological and psychiatric manifestations that are not specific to the disease and that can be found in other conditions. [ncbi.nlm.nih.gov]
The second developed progressive ataxia, accompanied by a vertical gaze palsy, when she was 13. [ncbi.nlm.nih.gov]
manifestations. [ncbi.nlm.nih.gov]
Psychiatric manifestations may remain isolated for several years. [dx.doi.org]
Alongside psychiatric disorders, patients develop early motor signs: ataxia, abnormal movements and, an almost consistent finding, vertical supranuclear gaze palsy. [ncbi.nlm.nih.gov]
Most notably, vertical supranuclear gaze palsy (VSGP) – particularly paresis of downgaze – is a highly specific and highly prevalent sign that may be present at an early stage [dx.doi.org]
According to the literature, this psychiatric manifestation resolves within 2 weeks of discontinuing the offending agent. [ncbi.nlm.nih.gov]
Most notably, vertical supranuclear gaze palsy (VSGP) – particularly paresis of downgaze – is a highly specific and highly prevalent sign that may be present at an early stage [doi.org]
Other psychiatric manifestations are also found, as behavioral, cognitive, learning, and mood disorders. However, they are less frequent. [ncbi.nlm.nih.gov]
Psychiatric manifestations as initial presentation for pediatric CNS germ cell tumors, a case series. Childs Nerv Syst 32 (8): 1359-62, 2016. [cancer.gov]
This phenomenon is caused by involvement of midbrain structures adjacent to the pineal GCT and is characterised by vertical gaze palsy, nystagmus on convergence and pupillary [tandfonline.com]
Trial Registration clinicaltrials.gov Identifier: NCT00139308 Tourette syndrome (TS) is characterized by motor and vocal tics associated with various psychiatric manifestations [dx.doi.org]
The neurological examination revealed vertical gaze palsy with preserved vertical oculocephalic movements. [ncbi.nlm.nih.gov]
manifestations that affect social and professional life. 1 Severe forms of the disease respond poorly to medical treatment, which has potentially serious side effects. 2 [dx.doi.org]
Examination shortly before death revealed hypomimia, dysarthria, vertical supranuclear gaze palsy and impaired postural reflexes. [actaneurocomms.biomedcentral.com]
[…] involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. [actaneurocomms.biomedcentral.com]
PSP presents classically with postural instability and falls, slurred speech, a vertical supranuclear gaze palsy and a dysexecutive syndrome[ 12 ], but there are a number [actaneurocomms.biomedcentral.com]
Psychiatric [ edit ] Various psychiatric manifestations have been associated with pituitary disorders including pituitary adenomas. [en.wikipedia.org]
Psychiatric manifestations may include depression, anxiety, easy irritability and emotional instability. It may also result in various cognitive difficulties. [en.wikipedia.org]
Psychiatric symptoms such as depression, anxiety [10] apathy, emotional instability, easy irritability and hostility have been noted. [11] Complications [ edit ] Acromegaly [en.wikipedia.org]
Most common symptoms are anosmia, headaches, and visual disturbances, but a range of manifestations, both neurologic and psychiatric, has been described in a significant number [symptoma.com]
Other features presenting later in life may include dystonia and vertical supranuclear gaze palsy, dementia and psychiatric manifestations. [genedx.com]
Examination showed ataxia, moderate cognitive impairment, and vertical gaze palsy. EEG revealed diffuse slowing and disorganization of background rhythms. [ncbi.nlm.nih.gov]
Individuals have been described in the medical literature with other psychiatric manifestations such as obsessive-compulsive disorder, bipolar disorders, and hallucinations [rarediseases.org]
Neuropsychiatric Manifestations of Colloid Cysts: a review of the literature. Psychiatr Danub. 2015 Sep. 27 Suppl 1:S315-20. [Medline]. [emedicine.medscape.com]
In this communication we describe an interesting case of multiple neurocysticercosis in a young presenting with psychiatric manifestations. [ncbi.nlm.nih.gov]
A sign of worsening hydrocephalus is vertical gaze palsy, the inability to gaze upward or downward when asked. The head of Mr. [americannursetoday.com]
“Psychiatric Manifestations of Neurocysticercosis: A Study of 38 Patients from a Neurology Clinic in Brazil,” Journal of Neurology, Neurosurgery & Psychiatry, Vol. 62, [scirp.org]
Psychiatric manifestations in systemic lupus erythematosus. Autoimmun Rev. 2007;6:421–6. [doi.org]
Neurologic and psychiatric manifestations of lead poisoning in adults (case report and review of the literature) [in German]. [ajnr.org]
HIV encephalopathy ( HIV-related encephalopathy ) a progressive primary encephalopathy caused by infection with human immunodeficiency virus type I, manifested by a variety [medical-dictionary.thefreedictionary.com]
Fortschr Neurol Psychiatr 1991 ; 59 : 413 –24 Tuzun M, Tuzun D, Salan A, et al. Lead encephalopathy: CT and MR findings. [ajnr.org]
It is very likely that the pineal plays a significant role in the manifestation of several mental illnesses. [thebridgelifeinthemix.info]
[…] eye movements Problems with the visual pathways in pineal tumors: Accommodation deficiency Oculomotor nerve palsy Failure of downward gaze Visual field disturbance (mass [pedsoncologyeducation.com]
Currently, much interest is focused on the role that melatonin may play in various psychiatric disorders, and pineal research now represents one of the active areas of current [thebridgelifeinthemix.info]
The disease usually presents in middle age, but one case of CJD in a 2 year old child was reported from Bombay. [8] Younger patients presenting with early psychiatric and [neurologyindia.com]
[…] behavioural manifestations have been reported from United Kingdom since 1994 and recently from some other European countries. [9], [10], [11] They subsequently developed cerebellar [neurologyindia.com]
These manifestations consist of epilepsy, intellectual disability, and neurobehavioral and psychiatric problems, including autism spectrum disorder. [docksci.com]
These lesions are associated with different neurological manifestations that are frequently associated with TSC. [docksci.com]
HIV encephalopathy ( HIV-related encephalopathy ) a progressive primary encephalopathy caused by infection with human immunodeficiency virus type I, manifested by a variety [medical-dictionary.thefreedictionary.com]
HIV encephalopathy, HIV-related encephalopathy AIDS encephalopathy; a progressive primary encephalopathy caused by human immunodeficiency virus type 1 infection, manifested [medical-dictionary.thefreedictionary.com]
[…] encephalopathy a condition, usually occurring secondary to advanced liver disease, marked by disturbances of consciousness that may progress to deep coma (hepatic coma), psychiatric [medical-dictionary.thefreedictionary.com]
Consequently, many of these patients were hospitalized with a range of other neurologic and psychiatric diagnoses. [cdc.gov]
Because cases were widely dispersed and initially involved atypical manifestations of acute botulism, many practitioners and specialists were misled in their primary diagnosis [cdc.gov]
Fortschr Neurol Psychiatr 1987;55:37–53. [karger.com]
These can result in: Ipsilateral lateral gaze palsy. Conjugate gaze palsy. Ocular bobbing. Midbrain syndromes: Vertical gaze palsy. Third cranial nerve palsy. [patient.info]
gaze palsy, lid retraction, pupillary light-near dissociation, convergence-retraction nystagmus Thalamic syndromes [11] Decreased arousal Variable sensory loss Aphasia Visual [amboss.com]
Individuals have been described in the medical literature with other psychiatric manifestations such as obsessive-compulsive disorder, bipolar disorders, and hallucinations [rarediseases.org]
[…] supranuclear gaze palsy (VSPG), dysarthria, dysphagia, dystonia, seizures, gelastic cataplexy, and psychiatric disorders. [orpha.net]
Vertical gaze palsy (the inability to move the eyes up and down), enlarged liver, enlarged spleen, or jaundice in young children are strong indications that NPC should be [nnpdf.org]
Find the answers you need on the hottest topics in neurology, including involuntary movement disorders; single gene mutations with neuropsychiatric manifestations; psychiatric [books.google.com]
vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. ( 24963673 ) Steele J.C....Olszewski J. 2014 8 Pseudobulbar paralysis in the Renaissance: Cosimo I de' [malacards.org]
Progressive supranuclear palsy: a heterogeneous degeneration involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia [dovemed.com]
Keywords Paraneoplastic neurological syndromes, onconeuronal antibodies, ion channel antibodies, surface antibodies, psychiatric manifestations, limbic encephalitis, therapy [touchneurology.com]
To identify an autoreactivity in a 66-year-old woman who presented with combined brainstem and cerebellar syndrome including vertical gaze palsy, severe progressive ataxia [ncbi.nlm.nih.gov]
manifestations, seizures, dyskinesias, dystonia, and autonomic instability. [questdiagnostics.com]
manifestations]; Psychosis; Mood instability; Schizophrenic symptoms (reported in 1 patient) MISCELLANEOUS: Slowly progressive; Highly variable phenotype with respect to [findzebra.com]
Upgaze palsy with gaze-evoked nystagmus can be a transient side effect of barbiturate toxicity (42). See Case 42. Supranuclear vertical gaze palsy. [neuroophthalmology.ca]
manifestations]; Diminished social interaction; Autistic features; Impulsivity; Poor attention span; Hyperactivity; Emotional lability MISCELLANEOUS: Childhood onset (average [findzebra.com]