Psychomotor-retardation: Causes & Reasons

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Possible Causes for psychomotor retardation

Depression

This is called psychomotor retardation. [health.com]

Changes in Activity or Energy Level Physical Changes Caused by Depression Unexplained aches and pains Weight loss or gain Decreased or increased appetite Psychomotor agitation [verywell.com]

Psychomotor agitation or retardation nearly every day. Fatigue or loss of energy nearly every day. [depression.org]

Endogenous Depression

It is generally accepted that endogenous depression includes marked vegetative changes, such as loss of appetite, loss of weight, loss of sleep, psychomotor retardation or [link.springer.com]

[…] score, presumably measuring mainly depressive mood and psychomotor retardation. [ncbi.nlm.nih.gov]

[…] depression major depressive disorder characterized by signs and symptoms of psychomotor retardation, such as burdened movements and slowed, toneless speech. en·dog·e·nous [medical-dictionary.thefreedictionary.com]

Reactive Depression

[…] depression major depressive disorder characterized by signs and symptoms of psychomotor retardation, such as burdened movements and slowed, toneless speech. re·ac·tive de [medical-dictionary.thefreedictionary.com]

“A patient who has psychomotor retardation, hypersomnia, and gaining weight is scored as having identical symptoms as another who is agitated, sleeping badly, and has weight [theatlantic.com]

It is often identified with a specific symptom complex—psychomotor retardation, early morning awakening, weight loss, excessive guilt, and lack of reactivity to the environment—that [medical-dictionary.thefreedictionary.com]

Suicidal Depression

Signs of depression may include the following: Psychomotor retardation or agitation, such as slowed speech, sighs, and long pauses Slowed body movements, even to the extent [emedicine.medscape.com]

Leigh's Disease

A 4 1/2-month-old girl suffered from psychomotor retardation, generalized hypotonia, poor feeding, hyperreflexia, nystagmus, optical atrophy and choreoathetosis from the age [ncbi.nlm.nih.gov]

A two-and-a-half-year-old male child presented with recurrent attacks of intractable vomiting, psychomotor retardation since 14 months of age. [ncbi.nlm.nih.gov]

Clinical features depend on which areas of the central nervous system are involved and include subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision [uniprot.org]

Farber Disease

retardation. [medical-dictionary.thefreedictionary.com]

retardation, and varying degrees of ocular, pulmonary or hepatic involvement. [ncbi.nlm.nih.gov]

The main features were a shrill voice, joint swelling, subcutaneous nodules and retarded psychomotor development. [ncbi.nlm.nih.gov]

Apathetic Thyrotoxicosis with Thyrotoxic Crisis

Dementia and severe psychomotor retardation may be the most prominent findings. 60 The Heart in Thyrotoxicosis. Thyrotoxicosis increases the work of the heart. [ahcmedia.com]

retardation, which may develop over a long period of time. 17 Patients also may present with weakness, arthralgias, and myalgias. [ahcmedia.com]

Caregivers may report that the patient has been acting confused, with memory problems. 16 The usual clinical findings in the elderly population are apathy and psychomotor [ahcmedia.com]

Lissencephaly

Symptoms of the disorder may include unusual facial appearance, difficulty swallowing, failure to thrive, muscle spasms, seizures, and severe psychomotor retardation. [ninds.nih.gov]

MR imaging of a patient with epilepsy and psychomotor retardation at 5 months revealed parieto-occipital pachygyria with almost normal cortical appearance and thickness in [ncbi.nlm.nih.gov]

retardation. [orpha.net]

Pelizaeus-Merzbacher Disease

Pelizaeus-Merzbacher disease (PMD) is a rare X-linked recessive disorder with severe psychomotor retardation and neurological symptoms due to an inborn abnormality of proteolipid [ncbi.nlm.nih.gov]

The typical clinical manifestations of PMD include psychomotor retardation, nystagmus, abnormal muscle tone, seizures, and cognitive impairment. [ncbi.nlm.nih.gov]

Diffuse hypotonia, nystagmus, psychomotor retardation, visual and hearing impairment have been observed in the patient since the age of 6 weeks. [ncbi.nlm.nih.gov]

Fucosidosis

In type 2, patients have angiokeratoma, milder psychomotor retardation and neurologic signs, longer survival, and normal salinity in the sweat. [ncbi.nlm.nih.gov]

Three sisters with adult fucosidosis showed prominent psychomotor retardation, gargoyle features, and angiokeratoma corporis diffusum, meeting the criteria for type II fucosidosis [ncbi.nlm.nih.gov]

Because of the slowly progressing psychomotor retardation and recurrent upper respiratory tract infections that the prognosis for patients with this disease is poor. [ncbi.nlm.nih.gov]

Aromatic L-Amino Acid Decarboxylase Deficiency

These patients were born to healthy and non-consanguineous parents, and presented oculogyric crises, paroxysmal dystonic attacks, and severe psychomotor retardation since [ncbi.nlm.nih.gov]

These findings suggested that the severe dystonic features were caused by abnormal function of bilateral basal ganglia and severe psychomotor retardation could be due to abnormalities [ncbi.nlm.nih.gov]

Pyruvate Carboxylase Deficiency

The most severe form (form B) is characterized by neonatal lethal lactic acidosis, whereas patients with form A suffer chronic lactic acidosis with psychomotor retardation [ncbi.nlm.nih.gov]

The most prominent symptom is psychomotor retardation. [ncbi.nlm.nih.gov]

Psychomotor retardation with seizures and spasticity are the major clinical manifestations. [merckmanuals.com]

Agitated Depression

[…] depression major depressive disorder characterized by signs and symptoms of psychomotor retardation, such as burdened movements and slowed, toneless speech. ag·i·tat·ed de [medical-dictionary.thefreedictionary.com]

Agitated Major Depressive Disorder At least 2 of the following manifestations of psychomotor retardation (not more subjective anxiety) are required for several days during [depression-guide.com]

When a young person presents with psychotic depression or psychomotor retardation, bipolar depression should be ruled out. [bmj.com]

Dysequilibrium Syndrome

retardation 0025356 Simplified gyral pattern 0009879 Truncal ataxia Instability or lack of coordination of central trunk muscles 0002078 Showing of 35 Last updated: 3/1/2020 [rarediseases.info.nih.gov]

Intention tremor 0002080 Nonprogressive 0003680 Pachygyria Fewer and broader ridges in brain 0001302 Pes planus Flat feet Flat foot [ more ] 0001763 Poor speech 0002465 Psychomotor [rarediseases.info.nih.gov]

Severe Depressive Episode

retardation. [behavenet.com]

retardation (a slowing of a person’s physical movements) for two months or more. [psychcentral.com]

Note: In children, consider failure to make expected weight gains. (4) Insomnia or Hypersomnia nearly every day (5) psychomotor agitation or retardation nearly every day [behavenet.com]

CHARGE Syndrome

In this report, we describe a patient with a typical phenotype characterized by psychomotor retardation, hypertrichosis, facial asymmetry, synophria, failure to thrive, developmental [ncbi.nlm.nih.gov]

Disease description A mitochondrial disorder with heterogeneous clinical manifestations including dysmorphic features, psychomotor retardation, hypotonia, growth retardation [uniprot.org]

Patients with a TMEM70 defect have a variable phenotype which may include, hypertrophic cardiomyopathy, myopathy, dysmorphism, cataracts, psychomotor retardation, lactic acidosis [invitae.com]

retardation, and, in most cases, 3-methyl-glutaconic aciduria. [basicmedicalkey.com]

Menkes Disease

Kinky-hair syndrome, a progressive neurodegenerative disorder which affects infant males and is characterized by unusual hair, seizures, psychomotor retardation, growth failure [jamanetwork.com]

These patients can present with failure to thrive, severe psychomotor retardation, seizures and hypopigmented hair, which is characteristic of this condition. [pediatricneurosciences.com]

Patients are normal in the first 2 or 3 months of life but then they develop failure to thrive, hypothermia, hypotonia, seizures, severe psychomotor retardation, and usually [neuropathology-web.org]

Hallervorden-Spatz Syndrome

We have correlated the clinical and histopathologic features of the eyes and central nervous system in a patient with Hallervorden-Spatz syndrome who died at age 11 years. The main ocular findings included degeneration of photoreceptors, marked thinning of the outer nuclear and outer plexiform layers, retinal[…] [ncbi.nlm.nih.gov]

Diffuse Cerebral Sclerosis of Schilder

retardation, involuntary movements, ataxia, and death in the second decade of life. [icd9data.com]

[…] pelizaeus-medrzbacher disease with normal proteolipid protein in its classical form, the disease has an onset in the first three months of life with nystagmus followed by slowly progressive psychomotor [icd9data.com]

Propionic Acidemia

The clinical picture varies from patients presenting with mild psychomotor retardation to those with severe metabolic decompensation with vomiting, dehydration, encephalopathy [webmedcentral.com]

retardation and chronic vomiting. [bjo.bmj.com]

[…] in the neonatal period with acute metabolic distress (AMD) and encephalopathy, but may present later in infancy in less severe deficiencies with recurrent ketoacidosis, psychomotor [bjo.bmj.com]

Congenital Hypothyroidism without Goiter

However, the brain is hypothyroid, causing incapacitating psychomotor retardation. [hdl.handle.net]

These patients presented with psychomotor retardation and characteristic thyroid function abnormalities, such as elevated T3 and low T4 levels. [ncbi.nlm.nih.gov]

[Patient and Methods]: 8-month-old male with severe axial hypotonia, psychomotor retardation and apparent hypothyroidism (TSH 7.7 mU/L, FT4 0.48 ng/dL) but elevated FT3 (8.86 [hdl.handle.net]

Alexander Disease

Symptomatically, AD is associated with leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation in infants, and usually leads to death within the first [ncbi.nlm.nih.gov]

He had megalencephaly, psychomotor retardation, seizures, and increasing elevation of increasing alpha-B crystallin and heat shock protein 27 in the cerebrospinal fluid. [ncbi.nlm.nih.gov]

He was clinically characterized by early onset of megalencephaly, psychomotor retardation, spasticity and recurrent seizure attacks. [ncbi.nlm.nih.gov]

Myxedema

2015 ICD-9-CM Diagnosis Code 244.9 Unspecified acquired hypothyroidism 2015 Billable Thru Sept 30/2015 Non-Billable On/After Oct 1/2015 ICD-9-CM 244.9 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 244.9 should only be used for claims with a date of service on or[…] [icd9data.com]

Infantile Neuronal Ceroid Lipofuscinosis

[symptoma.com] psychiatrical Psychomotor Retardation It is characterized by rapid deterioration with psychomotor retardation, loss of speech, seizures, ataxia, blindness, [symptoma.com]

It is characterized by rapid deterioration with psychomotor retardation, loss of speech, seizures, ataxia, blindness, hypotonia, microcephaly, and occasional convulsions. [icd10data.com]

Seizures (6 patients) and psychomotor retardation (1 patient) were the initial symptoms in the INCL group. All the patients in the group of LINCL had the usual findings. [scielo.br]

Smith-Magenis Syndrome

A 3-year-old girl was referred for evaluation of moderate psychomotor retardation and several behavioral problems including self-injuring behavior, hyperactivity, and sleep [ncbi.nlm.nih.gov]

The central nervous system is affected and this may be shown by psychomotor retardation, intellective deficit, electroencephalographic alterations (reduced/missing REM phase [ncbi.nlm.nih.gov]

[…] and growth retardation, and a 24-hour sleep disturbance. [ncbi.nlm.nih.gov]

Baraitser-Winter Syndrome

The overall risk of psychomotor retardation is high, but 34 of our 113 patients had an IQ greater than 70. [jamanetwork.com]

Most of the patients had severe psychomotor retardation with or without epilepsy (16 of 24), whereas only 5 patients had normal development or a mild mental deficit. [jamanetwork.com]

retardation, whereas 4 showed normal or near-normal mental development independent of epilepsy or the extent of MRI abnormalities ( Table 4 ). [jamanetwork.com]

Marshall-Smith Syndrome

Slow development of voluntary movements (psychomotor retardation) may also occur. [rarediseases.org]

Other symptoms include diminished muscle tone (hypotonia), muscle weakness, hernias in the abdomen (umbilical hernias), and/or mental retardation. [rarediseases.org]

Miller Dieker Syndrome

She underwent surgical closure of patent ductus arteriosus after birth; during development, she displayed psychomotor retardation, language impairment, and short stature. [elsevier.es]

retardation and infant death. [eyewiki.aao.org]

This conclusion is based on the fact that simultaneous deletion of YWHAE, CRK, and PAFAH1B1 results in severe lissencephaly.6 Our patient displayed psychomotor retardation [elsevier.es]

Coffin-Lowry Syndrome

Abstract The Coffin-Lowry syndrome (CLS), an X-linked disorder, is characterized by severe psychomotor retardation, facial and digital dysmorphisms, and progressive skeletal [ncbi.nlm.nih.gov]

Abstract Coffin-Lowry syndrome (CLS) is an X-linked disorder characterized by growth and psychomotor retardation, hypotonia and progressive skeletal changes. [ncbi.nlm.nih.gov]

Mutations in the RSK2 gene (RPS6KA3) on chromosome Xp22.2, have been found to cause Coffin-Lowry syndrome (CLS), an X-linked disorder characterized by psychomotor retardation [ncbi.nlm.nih.gov]