Puberty Delayed: Causes & Reasons

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Possible Causes for Puberty Delayed

Kallmann Syndrome

Kallmann syndrome and the related condition, congenital hypogonadotropic hypogonadism (CHH), are rare causes of delayed or absent puberty in both males and females. [delayed-puberty.com]

In six adolescents, we documented the association of either Kallmann syndrome or delayed puberty with agenesis of the lateral maxillary incisors. [ncbi.nlm.nih.gov]

[…] resembling delayed puberty; 2) in our experience, 12% of probands with KS have relatives with delayed puberty compared with 2% in the general population ( 11 ); and 3) a [academic.oup.com]

Growth Hormone Deficiency

If left untreated, the condition can result in shorter-than-average height and delayed puberty. Your body still needs growth hormone after you’ve finished puberty. [healthline.com]

[…] during puberty Headaches Symptoms of other pituitary hormone deficiencies that may co-exist with growth hormone deficiency: Absent or delayed sexual development during puberty [hopkinsmedicine.org]

If GHD develops later in a child’s life, such as from a brain injury or tumor, its main symptom is delayed puberty. In some instances, sexual development is halted. [healthline.com]

Celiac Disease

Despite resolution of acidosis on bicarbonate, she continued to have poor growth and delayed puberty. Investigations revealed autoimmune thyroiditis and celiac disease. [ncbi.nlm.nih.gov]

It occurs in children and adolescents with gastrointestinal symptoms, dermatitis herpetiformis, dental enamel defects, osteoporosis, short stature, delayed puberty and persistent [ncbi.nlm.nih.gov]

puberty. [ncbi.nlm.nih.gov]

Gaucher Disease

puberty Skeletal/bone dysfunction Menorrhagia Adult Organomegaly Malignancies Hematological abnormalities Bone dysfunction, especially osteopenia Elderly Parkinson disease [emedicine.medscape.com]

puberty, ecchymoses, and pingueculae. [merckmanuals.com]

[…] abnormalities, including bleeding events Bone pain crisis Skeletal/bone dysfunction - Avascular necrosis, osteopenia, pathologic fractures Adolescence Organomegaly Abnormal bleeding Delayed [emedicine.medscape.com]

Triple A Syndrome

This is the first report of triple A syndrome in Jordan with a novel indel mutation and presenting with delayed puberty. [ncbi.nlm.nih.gov]

Krupa B, Miazgowski T: Bone mineral density and markers of bone turnover in boys with constitutional delay of growth and puberty. [doi.org]

Since Klinefelter syndrome can be hard to notice, many parents don't know their son has it until he grows up or shows delays in puberty. [kidshealth.org]

LEOPARD Syndrome

Additional common features are café-au-lait spots (CLS), chest anomalies, cryptorchidism, delayed puberty, hypotonia, mild developmental delay, sensorineural deafness and [ncbi.nlm.nih.gov]

[…] menarche Delayed start of first period 0012569 Delayed puberty Delayed pubertal development Delayed pubertal growth Pubertal delay [ more ] 0000823 Delayed skeletal maturation [rarediseases.info.nih.gov]

Affected people may have abnormal genitalia ( cryptorchidism ), hypogonadism, or delayed puberty. [medical-dictionary-search-engines.com]

Gaucher Disease Type 1

A high prevalence (59.6%) of delayed puberty, which was more frequent with severe disease, was observed in 47 patients followed before and throughout puberty. [ncbi.nlm.nih.gov]

puberty Delayed pubertal development Delayed pubertal growth Pubertal delay [ more ] 0000823 Delayed skeletal maturation Delayed bone maturation Delayed skeletal development [rarediseases.info.nih.gov]

CONCLUSIONS: Growth retardation in childhood and delay of puberty are characteristic of Gaucher disease type 1 and are more frequent with severe disease. [ncbi.nlm.nih.gov]

Hypogonadism

Despite these advances, the key clinical question is to distinguish delayed puberty associated with an underlying pathology or hypogonadism from constitutional delay in growth [dx.doi.org]

delayed puberty, absence of pubertal development (i.e. [centerwatch.com]

Alternatively, in boys of short stature with delayed puberty, low testosterone plus low gonadotropin levels might result from constitutional delay of puberty. [msdmanuals.com]

Kallmann Syndrome Type 4

Use of the gonadotropin-releasing hormone agonist triptorelin in the diagnosis of delayed puberty in boys. J Pediatr 126:756-758, 1995. 8. [siicsalud.com]

Delayed Puberty. Delayed puberty is frequently reported in the family members of patients with CIHH (41). [78stepshealth.us]

Delayed puberty: analysis of a large case series from an academic center. J Clin Endocrinol Metab 87:1613-1620, 2002. 4. Grinspon RP, Rey RA. [siicsalud.com]

Hypogonadotropic Hypogonadism Type 18

Use of the gonadotropin-releasing hormone agonist triptorelin in the diagnosis of delayed puberty in boys. J Pediatr 126:756-758, 1995. 8. [siicsalud.com]

All these data hypothesis delay of puberty these patients enhanced height Age (years) occurred onset of puberty. mechanism increased height presumed delayed epiphyseal fusion [factpub.org]

Delayed puberty: analysis of a large case series from an academic center. J Clin Endocrinol Metab 87:1613-1620, 2002. 4. Grinspon RP, Rey RA. [siicsalud.com]

Hypogonadotropic Hypogonadism Type 22

Use of the gonadotropin-releasing hormone agonist triptorelin in the diagnosis of delayed puberty in boys. J Pediatr 126:756-758, 1995. 8. [siicsalud.com]

E29.8 Other testicular dysfunction E29.9 Testicular dysfunction, unspecified E30 Disorders of puberty, not elsewhere classified E30.0 Delayed puberty Constitutional delay [apps.who.int]

Delayed puberty: analysis of a large case series from an academic center. J Clin Endocrinol Metab 87:1613-1620, 2002. 4. Grinspon RP, Rey RA. [siicsalud.com]

Kallmann Syndrome Type 3

E29.8 Other testicular dysfunction E29.9 Testicular dysfunction, unspecified E30 Disorders of puberty, not elsewhere classified E30.0 Delayed puberty Constitutional delay [apps.who.int]

Partial defect in GnRH secretion Delayed puberty If very delayed, consider starting therapy with unopposed estrogen to allow breast development, then add a progestin. [depts.washington.edu]

Clinical evaluation for patients with normosmic IHH is challenging since symptoms are often consistent with constitutionally delayed puberty (CDP). [omicsonline.org]

X-Linked Hypogonadotropic Hypogonadism without Anosmia

In its most severe form, nXHH presents as a complete absence of puberty, but delayed puberty or post-pubertal symptom onset may also occur. [symptoma.com]

delayed penile growth. [symptoma.com]

While micropenis and/or cryptorchidism may suggest the disease in infancy or childhood, it is not usually diagnosed until puberty. [symptoma.com]

Hypogonadotropic Hypogonadism Type 8

Use of the gonadotropin-releasing hormone agonist triptorelin in the diagnosis of delayed puberty in boys. J Pediatr 126:756-758, 1995. 8. [siicsalud.com]

E29.8 Other testicular dysfunction E29.9 Testicular dysfunction, unspecified E30 Disorders of puberty, not elsewhere classified E30.0 Delayed puberty Constitutional delay [apps.who.int]

Clinical evaluation for patients with normosmic IHH is challenging since symptoms are often consistent with constitutionally delayed puberty (CDP). [omicsonline.org]

Hypogonadotropic Hypogonadism Type 21

AB - Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. [scholars.northwestern.edu]

Use of the gonadotropin-releasing hormone agonist triptorelin in the diagnosis of delayed puberty in boys. J Pediatr 126:756-758, 1995. 8. [siicsalud.com]

E29.8 Other testicular dysfunction E29.9 Testicular dysfunction, unspecified E30 Disorders of puberty, not elsewhere classified E30.0 Delayed puberty Constitutional delay [apps.who.int]

Familial Short Stature

[…] of growth and puberty Constitutional delayed growth and puberty Constitutional short stature Decrease in height Delayed growth and development Familial short stature Genetic [icd9data.com]

CDGP is the most common cause of short stature and delayed puberty. [en.wikipedia.org]

If there are no signs of puberty by 13 years, then puberty is delayed and further assessment is indicated. [endobible.com]

Kidney Disease

Kidney disease, or renal disease, also known as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation. Inflammation can be diagnosed by blood tests. Nephrosis is non-inflammatory kidney disease. Nephritis and[…] [en.wikipedia.org]

Mauriac Syndrome

It is characterized by hepatomegaly, growth and puberty delay, and the presence of elevated transaminases and serum lipids. [comum.rcaap.pt]

The male patient presented puberty delay and dyslipidemia. [elsevier.es]

[…] and growth delay, dyslipidemia, transaminase elevation and reduction of IGF1 (insulin-like growth factor 1).1 Cushingoid features may also be present.2 There may be different [elsevier.es]

Hypogonadotropic Hypogonadism

The diagnosis is usually made in adolescence because puberty is delayed or absent. Underdeveloped genitals and delayed puberty can be treated with hormone therapy. [thinkgenetic.com]

Both CDGP and CHH present with delayed puberty, and the distinction between these two entities during early adolescence is challenging. [ncbi.nlm.nih.gov]

Hypogonadotropic hypogonadism (HH) is characterised by delayed puberty and infertility. [ncbi.nlm.nih.gov]

Luteinizing Hormone Deficiency

A luteinizing hormone deficiency can result in delayed puberty and decrease in levels of hormones secreted from the gonads (hypogonadism). [healthhype.com]

Deficiency of LH can cause delay in puberty in boys and girls. [tandurust.com]

LH deficiency can manifest in females or males as delayed puberty, hypogonadism at any age, or reproductive abnormalities that can be dramatic or subtle. [thehealthscience.com]

Leydig Cell Hypoplasia due to LHB Deficiency

There was no family history of delayed puberty, infertility, or consanguinity ( Figure 1B ). [nejm.org]

puberty and infertility Hypothalamus, pituitary gland, and HPG axis GnRH and gonadotropins (FSH and LH) Sex hormones (androgens and estrogens) Kallmann syndrome and GnRH [en.wikipedia.org]

Delayed puberty is more common in boys than in girls. [gynecology.blogsky.com]

Boucher-Neuhäuser Syndrome

Usually this disorder is diagnosed at the onset of puberty (primary amenorrhea, poor development of sexual organs, sparse growth of secondary hair, short stature, delayed [accessanesthesiology.mhmedical.com]

Ataxia is often the initial symptom of the disorder, but vision problems or delayed puberty can be the earliest finding. [encyclopedia.pub]

His puberty was delayed. At 16 years of age, the patient experienced progressive deterioration of his balance and gait disturbance. [ncbi.nlm.nih.gov]

Ulnar Mammary Syndrome

Affected males consistently undergo delayed puberty, and both sexes have diminished to absent axillary hair. Imperforate hymen were seen in some affected women. [ncbi.nlm.nih.gov]

Subjects and methods Patients Both probands were referred for delayed puberty and midline defects. [ncbi.nlm.nih.gov]

puberty and genital anomalies. [ncbi.nlm.nih.gov]

Isolated Follicle Stimulating Hormone Deficiency

In girls, delayed puberty is when breast development has not started by age 13. The most common form of delayed puberty in boys is constitutional delay of puberty. [rileychildrens.org]

A luteinizing hormone deficiency can result in delayed puberty and decrease in levels of hormones secreted from the gonads (hypogonadism). [healthhype.com]

We report on 10 male patients, 16 to 28 years of age, suffering from idiopathic hypogonadotropic hypogonadism (IHH) including Kallman's syndrome (n = 2) and delayed puberty [thundersplace.org]

Precocious Puberty

Puberty Many children with delayed puberty will eventually go through an otherwise normal puberty, just at a late age. [nichd.nih.gov]

Delayed puberty is generally more common in boys. [nhs.uk]

Mutations that cause Noonan syndrome have been associated with delayed puberty. [ncbi.nlm.nih.gov]

Delayed Male Puberty

Epidemiology Exact prevalence of delayed puberty is not known. [patient.info]

Delayed Puberty Diagnosis Whether it’s delayed puberty in girls or delayed puberty in boys, the primary physician may be able to reassure the patient their development will [newportchildren.com]

Compare the differential diagnosis of delayed puberty for causes other than constitutional delay in girls versus boys. [pedsinreview.aappublications.org]

Froehlich Syndrome

From Wikidata Jump to navigation Jump to search hypothalamic disease that is characterized by endocrine dysfunction of the hypothalamic gland resulting in delayed puberty, [wikidata.org]

Disorders of Puberty: Delayed Puberty. In: Sperling MA. Ed. Pediatric Endocrinology. 1st ed. W.B. Saunders Company. Philadelphia, PA; 1996:454-460. [rarediseases.org]

Language Label Description Also known as English Froelich syndrome hypothalamic disease that is characterized by endocrine dysfunction of the hypothalamic gland resulting in delayed [wikidata.org]

Delayed Menarche

Delayed Puberty. News-Medical. Retrieved on November 02, 2022 from https://www.news-medical.net/health/Delayed-Puberty.aspx. MLA Smith, Yolanda. "Delayed Puberty". [news-medical.net]

[…] have developed breasts but their periods haven't started by 15 Causes of delayed puberty It's not always clear what causes delayed puberty. [nhs.uk]

Compare the differential diagnosis of delayed puberty for causes other than constitutional delay in girls versus boys. [pedsinreview.aappublications.org]

Primary Amenorrhea

Primary amenorrhea can be a sign of either delayed puberty or Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. [ncbi.nlm.nih.gov]

Only one mutation was associated with a complete phenotype, including delayed puberty, primary amenorrhea, and small ovaries. [ncbi.nlm.nih.gov]

Kulin Delayed puberty [2.] C. Traggiai, R. Stanhope Delayed puberty [3.] I.L. Sedlmeyer, M.R. [elsevier.es]

Camurati-Engelmann Syndrome

[…] eruption of teeth Delayed eruption Delayed teeth eruption Delayed tooth eruption Eruption, delayed Late eruption of teeth Late tooth eruption [ more ] 0000684 Delayed puberty [rarediseases.info.nih.gov]

Other features of Camurati-Engelmann disease include abnormally long limbs in proportion to height, a decrease in muscle mass and body fat, and delayed puberty. [xpertdox.com]

Other features of Camurati-Engelmann disease include abnormally long limbs in proportion to height, a decrease in muscle mass and body fat, and delayed puberty.[1][2] In the [rarediseases.info.nih.gov]