Create issue ticket

1,609 Possible Causes for Purpura, Splenomegaly

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[] These complications may include hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura, and disseminated intravascular coagulation. 2 These complications[] […] clinical symptoms were also described such as erythema multiforme-like and herpetiform lesions, urticaria, petechiae, transient cold urticaria, immune-related thrombocytopenic purpura[]

  • Familial Mediterranean Fever

    Her persistent left elbow effusion resolved and her splenomegaly rapidly disappeared.[] It is also known as anaphylactoid purpura, allergic vasculitis, and rarely, as rheumatoid purpura [ 3 ].[] […] expressions, such as of M694V/M694V homozygous, are more likely to have involvement of arthritis, renal amyloidosis, erysipelas-like skin lesions, oral lesions, higher fever, and splenomegaly[]

  • Essential Thrombocythemia

    And the clinical characteristics of ET patients, such as WBC counts, hemoglobin level, splenomegaly and thrombosis, were influenced by JAK2V617F mutation burden.[] […] hypergammaglobulinemic purpura ( D89.0 ) cryoglobulinemic purpura ( D89.1 ) essential (hemorrhagic) thrombocythemia ( D47.3 ) hemorrhagic thrombocythemia ( D47.3 ) purpura[] […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[]

  • Malignant Histiocytosis

    The long duration of massive splenomegaly suggests that this patient could represent a chronic form of MH.[] In case 2 the diagnosis was initially idiopathic thrombocytopenia purpura but he deteriorated on steroids, and was subsequently unsuccessfully treated with chemotherapy and[] IDIOPATSKA TROMBOCITOPENIČNA PURPURA (ITP) ali AVTOIMUNA TROMBOCITOPENIČNA PURPURA Je pridobljena bolezen, ki se pojavlja v otroštvu in odrasli dobi.[]

  • Relapsing Fever

    Splenomegaly was the second most common finding reported. Diagnosis of relapsing fever was made in 20 cases by identifying spirochetes on peripheral blood smears.[] Papules (small lumps), petechiae (small red or purple spots due to bleeding into the skin), purpura (bleeding into the skin, includes petechiae and bruises), and facial flushing[] Malaria and babesiosis cause hemolytic anemia and may be associated with hepatomegaly and splenomegaly. Recurring fever is typical of malaria and Borrelia infection.[]

  • Waldenstrom Macroglobulinemia

    Manifestations of macroglobulinemic lymphoma include lymphadenopathy, splenomegaly and bone marrow involvement.[] Cutaneous manifestations are usually nonspecific such as purpura, ulcers, and urticarial lesions.[] CT-identified splenomegaly was reported in 6 of the 31 patients at baseline.[]

  • Immune Thrombocytopenic Purpura

    Clinical examination revealed mucosal hemorrhages and splenomegaly.[] Immune thrombocytopenic purpura (ITP), also called primary immune thrombocytopenia or idiopathic thrombocytopenic purpura, is an autoimmune disease affecting thrombocytes.[] There is no evidence of splenomegaly on abdominal exam.[]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[] Thrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia that requires emergent treatment with plasma exchange and is one of the most important conditions[] Hepatomegaly and splenomegaly may be present.[]

  • Hairy Cell Leukemia

    Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[] In addition, patients may present with cutaneous manifestations, such as herpes zoster, cellulitis, abscess, pyoderma, dermatophytosis, leukemia cutis, ecchymosis, and purpura[] It typically affects middle-aged to elderly male who present with pancytopenia and massive splenomegaly. Lymphadenopathy is usually not seen.[]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[] Thrombotic thrombocytopenic purpura – This results in the reduction of platelet production and bleeding tendencies.[] The unusual case of myeloproliferative disease described here is characterized by the following features: (1) a clinically completely silent course for 11 years without splenomegaly[]

Further symptoms

Similar symptoms