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1,609 Possible Causes for Purpura, Splenomegaly

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] These complications may include hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura, and disseminated intravascular coagulation. 2 These complications[uspharmacist.com] […] clinical symptoms were also described such as erythema multiforme-like and herpetiform lesions, urticaria, petechiae, transient cold urticaria, immune-related thrombocytopenic purpura[omicsonline.org]

  • Familial Mediterranean Fever

    Her persistent left elbow effusion resolved and her splenomegaly rapidly disappeared.[bloodjournal.org] It is also known as anaphylactoid purpura, allergic vasculitis, and rarely, as rheumatoid purpura [ 3 ].[rheumatology.oxfordjournals.org] […] expressions, such as of M694V/M694V homozygous, are more likely to have involvement of arthritis, renal amyloidosis, erysipelas-like skin lesions, oral lesions, higher fever, and splenomegaly[symptoma.com]

  • Essential Thrombocythemia

    And the clinical characteristics of ET patients, such as WBC counts, hemoglobin level, splenomegaly and thrombosis, were influenced by JAK2V617F mutation burden.[ncbi.nlm.nih.gov] […] hypergammaglobulinemic purpura ( D89.0 ) cryoglobulinemic purpura ( D89.1 ) essential (hemorrhagic) thrombocythemia ( D47.3 ) hemorrhagic thrombocythemia ( D47.3 ) purpura[icd10data.com] […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[ncbi.nlm.nih.gov]

  • Malignant Histiocytosis

    The long duration of massive splenomegaly suggests that this patient could represent a chronic form of MH.[ncbi.nlm.nih.gov] In case 2 the diagnosis was initially idiopathic thrombocytopenia purpura but he deteriorated on steroids, and was subsequently unsuccessfully treated with chemotherapy and[ncbi.nlm.nih.gov] IDIOPATSKA TROMBOCITOPENIČNA PURPURA (ITP) ali AVTOIMUNA TROMBOCITOPENIČNA PURPURA Je pridobljena bolezen, ki se pojavlja v otroštvu in odrasli dobi.[forumi.siol.net]

  • Relapsing Fever

    Splenomegaly was the second most common finding reported. Diagnosis of relapsing fever was made in 20 cases by identifying spirochetes on peripheral blood smears.[ncbi.nlm.nih.gov] Papules (small lumps), petechiae (small red or purple spots due to bleeding into the skin), purpura (bleeding into the skin, includes petechiae and bruises), and facial flushing[dermnetnz.org] Malaria and babesiosis cause hemolytic anemia and may be associated with hepatomegaly and splenomegaly. Recurring fever is typical of malaria and Borrelia infection.[mdedge.com]

  • Waldenstrom Macroglobulinemia

    Manifestations of macroglobulinemic lymphoma include lymphadenopathy, splenomegaly and bone marrow involvement.[ncbi.nlm.nih.gov] Cutaneous manifestations are usually nonspecific such as purpura, ulcers, and urticarial lesions.[ncbi.nlm.nih.gov] CT-identified splenomegaly was reported in 6 of the 31 patients at baseline.[onclive.com]

  • Immune Thrombocytopenic Purpura

    Clinical examination revealed mucosal hemorrhages and splenomegaly.[ncbi.nlm.nih.gov] Immune thrombocytopenic purpura (ITP), also called primary immune thrombocytopenia or idiopathic thrombocytopenic purpura, is an autoimmune disease affecting thrombocytes.[symptoma.com] There is no evidence of splenomegaly on abdominal exam.[medbullets.com]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Thrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia that requires emergent treatment with plasma exchange and is one of the most important conditions[ncbi.nlm.nih.gov] Hepatomegaly and splenomegaly may be present.[patient.info]

  • Hairy Cell Leukemia

    Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[ncbi.nlm.nih.gov] In addition, patients may present with cutaneous manifestations, such as herpes zoster, cellulitis, abscess, pyoderma, dermatophytosis, leukemia cutis, ecchymosis, and purpura[hematologyandoncology.net] It typically affects middle-aged to elderly male who present with pancytopenia and massive splenomegaly. Lymphadenopathy is usually not seen.[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura – This results in the reduction of platelet production and bleeding tendencies.[news-medical.net] The unusual case of myeloproliferative disease described here is characterized by the following features: (1) a clinically completely silent course for 11 years without splenomegaly[ncbi.nlm.nih.gov]

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