Pyramidal Tract Signs: Causes & Reasons

Possible Causes for Pyramidal Tract Signs

Abstract Background: The combination of early-onset, progressive parkinsonism with pyramidal tract signs has been known as pallido-pyramidal or parkinsonian-pyramidal syndrome [n.neurology.org]

BACKGROUND:: The combination of early-onset, progressive parkinsonism with pyramidal tract signs has been known as pallido-pyramidal or parkinsonian-pyramidal syndrome since [moh-it.pure.elsevier.com]

The phenotype associated with FBXO7 mutations consisted of early-onset, progressive parkinsonism and pyramidal tract signs, thereby matching clinically the pallido-pyramidal [n.neurology.org]

Pyramidal Tract Lesion

Babinski sign in absence of Pyramidal Tract Lesion can occur in physiological and pathological conditions Physiological causes of Babinski sign in absence of Pyramidal Tract [notes.medicosnotes.com]

A positive sign in Rossolimo’s reflex test is plantar flexion of toes which indicates pyramidal tract lesion. [dynamicpath.com]

Neurological examination revealed bilateral pyramidal-tract signs, and paresis of the right arm. [em-consulte.com]

Infantile Neuroaxonal Dystrophy

tract signs, marked hypotonia and early visual disturbances without epileptic seizures. [ncbi.nlm.nih.gov]

tract signs. [cags.org.ae]

tract signs and spastic tetraplegia. [globalgenes.org]

Cerebrotendinous Xanthomatosis

tract signs, and cerebellar deficits (15). [ncbi.nlm.nih.gov]

The distribution of lesions along corticospinal tracts or in the cerebellum were consistent with the clinical presentation of pyramidal or cerebellar signs, whereas abnormalities [ncbi.nlm.nih.gov]

tracts; initial signs of cerebral atrophy may also present be with enlargement of both the insular and frontal spaces (13). [ncbi.nlm.nih.gov]

Lathyrism

Abstract Lathyrism, a form of motoneuron disease induced by excessive consumption of th legume Lathyrus sativus (chickling pea), presents as signs of pyramidal tract involvement [ncbi.nlm.nih.gov]

[…] of pyramidal tract involvement. [unboundmedicine.com]

tracts producing signs of upper motor neuron damage. [en.wikipedia.org]

Hallervorden-Spatz Syndrome

tract signs. 1 Choreoathetotic movements or tremor may also be present but these features have not been described in isolation. [jnnp.bmj.com]

tract signs.1 Choreoathetotic movements or tremor may also be present but these features have not been described in isolation. [jnnp.bmj.com]

Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs [medresearch.in]

Friedreich Ataxia

tract signs, scoliosis, and in some, cardiomyopathy, diabetes mellitus, visual loss and defective hearing. [orpha.net]

[…] inherited neurodegenerative disorder classically characterized by progressive gait and limb ataxia, dysarthria, dysphagia, oculomotor dysfunction, loss of deep tendon reflexes, pyramidal [orpha.net]

Spastic Paraplegia

SPG17 is characterized by prominent amyotrophy of the hand muscles, the presence of mild to severe pyramidal tract signs and spastic paraplegia. [uniprot.org]

[…] than the pyramidal tract signs. [nature.com]

In addition to pure forms, in which symptoms are limited to lower limb pyramidal tract dysfunction, complicated forms exist with additional neurological signs and usually [nature.com]

Spinocerebellar Ataxia Type 13

However, other common SCA28 features like pyramidal tract signs (lower limb hyperreflexia, positive Babinski sign), ophthalmoparesis or ptosis were absent. [lf2.cuni.cz]

Hereditary Spastic Paraplegia

We present three patients with complicated HSP from two unrelated families, who had early onset progressive cerebellar signs and developed pyramidal tract signs during follow-up [ncbi.nlm.nih.gov]

tract dysfunction. [ncbi.nlm.nih.gov]

In view of their known functional role, damage to these central nervous gray and white matter components offers explanations for the patient's pyramidal signs, her cerebellar [ncbi.nlm.nih.gov]

Acute Transverse Myelitis

Flaccid weakness gradually changes to pyramidal tract signs, with hyperreflexia, clonus, and extensor responses. [pediatricneurologybriefs.com]

Spinocerebellar Ataxia Type 1

[…] system (CNS) involvement consisting of cerebellar ataxia and pyramidal tract signs. [ncbi.nlm.nih.gov]

signs, ophthalmoparesis, and extrapyramidal involvement. [doi.org]

In this family, affected members have been reported to show typical clinical features of FAP, and some have been documented to exhibit symptoms and signs of central nervous [ncbi.nlm.nih.gov]

Marchiafava-Bignami Disease

Type A: acute to subacute onset of consciousness impairment, pyramidal tract signs, limb hypertonia, seizures, hyperintense swelling of the corpus callosum on T2-weighted [jcdr.net]

Radiology has helped to identify two subgroups: Type A is characterised by coma, stupor and pyramidal tract features. [patient.info]

Signs Usually nonspecific. A generally dishevelled condition is suggestive of chronic alcohol problems. [patient.info]

Benedict Syndrome

tract MLF Medial Lemniscus Medial Medullary Syndrome Signs Ipsilateral Paralysis of Tongue Contralateral Paralysis of arm and leg Contralateral Impared proprioceptive sense [quizlet.com]

[…] such as dysphagia due to lower cranial nerve involvement, facial nerve palsies, Horners syndrome, vertigo +/- hearing loss, and pyramidal long tract signs => see the appendix [lifeinthefastlane.com]

These signs are attributed to the involvement of the pyramidal tract rostral to their decussation, the fibers and nucleus of the hypoglossal nerve, and the medial lemniscus [neupsykey.com]

Hemiparesis

Also, myoclonus or tremor is seen in up to 38% patients, hyperreflexia and other pyramidal tract signs in 85% patients and psychosis, visual hallucinations and paranoid delusions [ijcasereportsandimages.com]

[…] and Fractional Anisotropy in the Pyramidal Tract. [scindeks.ceon.rs]

Miyashita, M., Hiramatsu, R., Murao, K., Kondo, A., Tanabe, H., Kuroiwa, T. (2008) Diffusion Tensor Imaging in Chronic Subdural Hematoma: Correlation between Clinical Signs [scindeks.ceon.rs]

Subacute Combined Degeneration of Spinal Cord

Both patients showed clinical and electrophysiological damage to the posterior column and no signs of pyramidal tract involvement. [jnnp.bmj.com]

A midline lesion of the medulla oblongata is likely to involve the pyramidal tracts (the descending motor pathway) and the medial lemnisci (the ascending tracts relaying sensory [britannica.com]

tract damage was graded as 1=positive Babinski sign, 2=spastic paraparesis, or 3=spastic tetraparesis. [jnnp.bmj.com]

Upper Motor Neuron Disease

Increased deep tendon reflex (DTR) Pronator drift [3] Corticospinal/pyramidal tract [ edit ] These are the neural tracts which descend in the ventral horn of the spinal cord [en.wikipedia.org]

The presence of the Babinski sign after 12 months is the sign of a non-specific upper motor neuron lesion. [en.wikipedia.org]

Amyotrophic Lateral Sclerosis

Autosomal dominant juvenile amyotrophic lateral sclerosis and distal hereditary motor neuronopathy with pyramidal tract signs: synonyms for the same disorder? [ncbi.nlm.nih.gov]

Signs of pyramid release are not always marked and, only recently, non-invasive tests to reveal cortical spinal tract commitment have been incorporated into the medical practice [doi.org]

Hereditary ATTR Amyloidosis

Furuya H et al. (1987) Molecular analysis of a variant type of familial amyloidotic polyneuropathy showing cerebellar ataxia and pyramidal tract signs. [^] 23. [moldiag.com]

Paraparesis

Pyramidal signs of the lower limbs, upper limbs, posterior column involvement and spinothalamic tract dysfunction were the common signs. [neurologyindia.com]

Paraplegia

Is it a anterior horn cell+ pyramidal tract lesion • Diffuse LMN Signs and Diffuse UMN signs • Sluggish DTR in upper limbs Exaggerated in lower limbs • Abdominal reflexes [slideshare.net]

Most common is AD (70% to 80%)  characterized by progressive lower limb spasticity secondary to pyramidal tract dysfunction.  results in brisk DTR, extensor planters, muscle [slideshare.net]

[…] weakness, abnormal gait and variable bladder disturbances.  HSP are often mistakenly diagnosed as cerebral palsy  It is classified as pure if neurologic signs are limited [slideshare.net]

Central Pontine Myelinolysis

In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which [omicsonline.org]

Thoracic Spinal Cord Tumor

Weakness is due to the involvement of the pyramidal or corticospinal tract. The degree of motor impairment may range from clumsiness to complete quadriplegia. [neurospinewi.com]

Myelopathy may be evident with central spinal cord tumors, resulting in spasticity, paresis, hyperactive reflexes, Babinski’s sign. [neurospinewi.com]

Brown-Sequard Syndrome

pyramidal tract dysfunction, with contralateral loss of pain and temperature due to involvement of the lateral spinothalamic tract [4]. [bmcneurol.biomedcentral.com]

positive Babinski sign Loss of vibration and fine-touch sensation (numbness, paresthesias) Other Optic neuritis, internuclear ophthalmoplegia Charcot neurological triad [www-amboss-com.db.rsu.lv]

Anterior cord syndrome is the most common, while Brown-Séquard syndrome such as in our patient, is rare, with a constellation of ipsilateral signs of posterior column and [bmcneurol.biomedcentral.com]

Klippel-Feil Syndrome

The eponymous positive Babinski sign signifies disturbance of the pyramidal tract by upward movement of the great toe [7]. [karger.com]

Connatal Pelizaeus-Merzbacher Disease

Generally, clinical diagnosis of PMD is straightforward if all signs of pyramidal, extrapyramidal and cerebellar tracts are evident. [nature.com]

Neurological examination revealed rigidity and spasticity due to exaggerated deep tendon reflex and Babinski signs. [nature.com]

Alzheimer Disease

Alzheimer's is a type of dementia that causes problems with memory, thinking and behavior. Symptoms usually develop slowly and get worse over time, becoming severe enough to interfere with daily tasks. Alzheimer's and dementia basics Alzheimer's is the most common cause of dementia, a general term for memory loss[…] [alz.org]

Stroke

OBJECTIVE: ed to investigate the association between blood pressure and acute phase stroke lethality in a Brazilian intensive care unit. METHODS: This was an observational, prospective cohort study of hemorrhagic and ischemic stroke intensive care patients. The primary outcome was all-cause mortality during the[…] [ncbi.nlm.nih.gov]

Hernia

A hernia is the protrusion of organs, such as intestines, through a weakened section of the abdominal wall. If left untreated, the split in the muscle widens and greater amounts of tissue or organs are pushed through the opening, forming a sac. This visible lump or bulge is one of the key characteristics of a[…] [betterhealth.vic.gov.au]

Primary Progressive Multiple Sclerosis

We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…] [ncbi.nlm.nih.gov]