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35 Possible Causes for Pyramidal Tract Signs, Rapid Progression to Disability

  • Alzheimer Disease

    Our findings may reflect the presence of greater comorbidity leading to earlier death among men than among women with AD, 57 or a more rapid progression of AD in women. 58[dx.doi.org] - 61 The inherent survival advantage of women in general may lead women to live longer, tolerating greater disability, than men.[dx.doi.org]

  • Primary Progressive Multiple Sclerosis

    Although progression is more rapid, age-related disability milestones are identical to relapsing-onset disease.[ncbi.nlm.nih.gov] A previous analysis of the British Columbia MS database challenged the view that disability progression is rapid in PPMS, but identified few predictors of disease progression[ncbi.nlm.nih.gov] , for which prognosis is considered as poor due to the relatively rapid development of advanced disability as compared with RRMS.[globenewswire.com]

  • Amyotrophic Lateral Sclerosis

    Autosomal dominant juvenile amyotrophic lateral sclerosis and distal hereditary motor neuronopathy with pyramidal tract signs: synonyms for the same disorder?[ncbi.nlm.nih.gov] One woman with ALS received intracranial injection of adult olfactory ensheathing glia (OEG) transplantation and her disease progressed at a more rapid rate after the procedure[doi.org] Signs of pyramid release are not always marked and, only recently, non-invasive tests to reveal cortical spinal tract commitment have been incorporated into the medical practice[doi.org]

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] Rapid progression of the disease may lead to severe disability, life-threatening state, the status dystonicus, and several critical events such as hyperpyrexia, dehydration[file.scirp.org] tract signs. 1 Choreoathetotic movements or tremor may also be present but these features have not been described in isolation.[jnnp.bmj.com]

  • Myelitis

    […] one third remain severely disabled Poor prognostic indicators rapid progression of symptoms back pain spinal shock absent central conduction on somatosensory evoked potential[lifeinthefastlane.com] Progression ; Transverse myelitis (TM) The progression is rapid • time to maximal disability is more than 4 hr and fewer than 21 days. A.[slideshare.net] The rapid progression of clinical symptoms, the presence of back pain, and the presence of spinal shock, as well as para-clinical evidence, such as absent central motor conduction[rarediseases.org]

  • Paraparesis

    Age of onset at 50 years or older and high HTLV-1 proviral load are associated with a more rapid progression to a severe disability. [4] Patients may survive for 10-40 years[emedicine.medscape.com]

  • Multiple Sclerosis

    progression of disability, more frequent relapses, and worse postrelapse recoveries.[dx.doi.org] Multiple Sclerosis have a higher incidence of spinal cord lesion and exhibit much more rapid development of disability than those with other forms of the disease 1 in every[themcfox.com] Relapses are associated with more rapid disability progression in SPMS but tend to occur in those at younger ages (younger than 55 years) and earlier in the disease course[doi.org]

  • Subacute Transverse Myelitis

    Progression ; Transverse myelitis (TM) The progression is rapid • time to maximal disability is more than 4 hr and fewer than 21 days. A.[slideshare.net]

  • Cervical Spinal Cord Tumor

    Surgery is indicated if the diagnosis is in doubt, a tissue diagnosis is required, the spine is unstable or neurologic deterioration is severe, rapid and progressive.[aafp.org] Surgery is also indicated if decompression by radiation therapy is not expected to become effective in time to save a patient from severely disabling neurologic deficits.[aafp.org]

  • Transverse Myelitis

    […] one third remain severely disabled Poor prognostic indicators rapid progression of symptoms back pain spinal shock absent central conduction on somatosensory evoked potential[lifeinthefastlane.com] Progression ; Transverse myelitis (TM) The progression is rapid • time to maximal disability is more than 4 hr and fewer than 21 days. A.[slideshare.net] The rapid progression of clinical symptoms, the presence of back pain, and the presence of spinal shock, as well as para-clinical evidence, such as absent central motor conduction[rarediseases.org]

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