Rapid Onset: Causes & Reasons

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Possible Causes for Rapid Onset

Disorder of the Sacrum

Synonyms of Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation late onset central hypoventilation syndrome with hypothalamic dysfunction [rarediseases.org]

Abstract Introduction: Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) is a rare disease. [pedinfect.com]

Review article DOI: 10.1016/j.nrleng.2016.04.003 Rapid-onset obesity with hypothalamic dysregulation, hypoventilation, and autonomic dysregulation (ROHHAD syndrome): A case [elsevier.es]

Rib Fracture

Abstract Introduction: Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) is a rare disease. [pedinfect.com]

Review article DOI: 10.1016/j.nrleng.2016.04.003 Rapid-onset obesity with hypothalamic dysregulation, hypoventilation, and autonomic dysregulation (ROHHAD syndrome): A case [elsevier.es]

Adult-Onset Cervical Dystonia Type DYT23

[…] dysphonia ( DYT4 ), dopa⁃responsive dystonia ( DYT5 ), mixed-type dystonia ( DYT6 ), paroxysmal kinesigenic dyskinesia ( DYT10 ), myoclonus⁃dystonia syndrome ( DYT11 ), rapid-onset [cjcnn.org]

Primary dystonia, DYT13 type Primary dystonia, DYT17 type Primary dystonia, DYT2 type Primary dystonia, DYT21 type Primary dystonia, DYT4 type Primary dystonia, DYT6 type Rapid-onset [se-atlas.de]

For example, a sudden-onset dystonia disorder is compatible with rapid-onset dystonia-parkinsonism. [docslide.net]

ROHHAD Syndrome

Twenty-three children with what we are now naming rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation were identified. [doi.org]

Figure 1: Growth chart shows rapid-onset obesity. [chop.edu]

The most characteristic manifestations were the presentation of rapid-onset obesity in the first 10 years of life (median age at onset: 3 years), followed by hypothalamic [doi.org]

Alternating Hemiplegia of Childhood

Gene sequencing revealed an identical ATP1A3 mutation as in three typical adult-onset rapid-onset dystonia parkinsonism cases but never previously described in an alternating [ncbi.nlm.nih.gov]

BACKGROUND: ATP1A3 mutations have now been recognized in infants and children presenting with a diverse group of neurological phenotypes, including Rapid-onset Dystonia-Parkinsonism [ncbi.nlm.nih.gov]

[…] cohort with those of patients with rapid-onset dystonia-parkinsonism reported in the scientific literature. [ncbi.nlm.nih.gov]

Staphylococcal Food Poisoning

Due to the rapid onset of symptoms (vomiting, diarrhea), the food samples were analyzed for the presence of toxigenic bacteria and their toxins; nasopharyngeal swabs were [ncbi.nlm.nih.gov]

The rapid onset of symptoms, lack of fever, and epidemic nature of the presentation can be indicators of staphylococcal food poisoning. [visualdx.com]

According to CDC, Staphylococcus intoxication begins with a rapid onset of nausea, along with violent vomiting, abdominal cramping and diarrhea. [foodsafetynews.com]

Heparin-Induced Thrombocytopenia

Furthermore, their rapid onset of action and induction of effective anticoagulation provide a favorable basis for their use in this condition. [ncbi.nlm.nih.gov]

[…] of unfractionated heparin (UFH) for the treatment of CST, his platelet count fell precipitously and he developed deep vein thrombosis, a clinical picture consistent with rapid-onset [ncbi.nlm.nih.gov]

Type I, or drug-induced non-immune HIT, has a rapid onset with mild, transit, and reversible course of the reduction of platelet. [consultant360.com]

Rhinophyma

Endocrine manifestations of the rapid-onset obesity with hypoventilation, hypothalamic, autonomic dysregulation, and neural tumor syndrome. [adc.bmj.com]

Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation presenting in childhood. [pedinfect.com]

Acute Epiglottitis

We describe a 48-year-old woman with epiglottitis and associated typical rapid onset of sore throat, fever, respiratory distress, and swollen, red supraglottic structures. [ncbi.nlm.nih.gov]

Acute epiglottitis is a rapid-onset bacterial infection that results in sudden inflammation of the epiglottis and the tissues around the epiglottis. - It can lead to blockage [nursingtimes.net]

Rapid onset of dysphagia was the other predominant symptom. [article.sapub.org]

Succinylcholine Allergy

Succinylcholine (Anectine) chloride is a "depolarizing" type of muscle relaxant with action of rapid onset and short duration. [jamanetwork.com]

Editor, Since 1952, succinylcholine has been widely used worldwide as the first choice of muscle relaxant to facilitate tracheal intubation in rapid sequence induction of [ncbi.nlm.nih.gov]

Despite its unique properties (i.e. short onset and offset and intense blockade), succinylcholine may induce some severe adverse reactions, such as anaphylactic reactions.1,2 [ncbi.nlm.nih.gov]

CAPOS Syndrome

Mutations in ATP1A3 cause AHC ( alternating hemiplegia of childhood) and RDP (rapid-onset dystonia-parkinsonism ). [rareconnect.org]

CONCLUSION Other mutations in ATP1A3 have previously been demonstrated to cause rapid-onset dystonia-parkinsonism (also called dystonia-12) or alternating hemiplegia of childhood [unboundmedicine.com]

Conclusion Other mutations in ATP1A3 have previously been demonstrated to cause rapid-onset dystonia-parkinsonism (also called dystonia-12) or alternating hemiplegia of childhood [summit.sfu.ca]

Chronic Polyneuropathy

Atypical CIDP variants are increasingly recognized, including subtypes with rapid onset as well as variants with pure sensory, focal or marked asymmetrical deficits. [thieme-connect.com]

Childhood Absence Seizures

Behavioral analysis also showed rapid onset and end of deficits associated with electrographic seizure start and end. [ncbi.nlm.nih.gov]

EEG time-frequency analysis revealed abrupt onset and end of 3-4 Hz spike-wave discharges with a mean duration of 6.6 s. [ncbi.nlm.nih.gov]

Primary Dystonia Type DYT2

DYT10 Paroxysmal kinesigenic choreoathetosis Autosomal dominant 16p-q Unknown DYT11 Myoclonus dystonia Autosomal dominant (maternal imprinting) 7q11q25 ε-Sarcoglycan DYT12 Rapid-onset [nature.com]

jerk like movements, response to alcohol combined with variable degrees of dystonia DYT-12 ATP1A3 19q13 Rapid Onset Dystonia-Parkinsonism Autosomal Dominant Acute or subacute [cmdg.org]

Rapid-Onset Dystonia-Parkinsonism. In: NORD Guide to Rare Disorders. Lippincott Williams & Wilkins. Philadelphia, PA. 2003:617-618. [rarediseases.org]

Hypothalamic Dysfunction

It mimics many other diseases and it may take few years after the onset of rapid obesity to have the other clinical features. [ncbi.nlm.nih.gov]

RESULTS: Twenty-three children with what we are now naming rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation were identified. [ncbi.nlm.nih.gov]

[…] whenever early rapid onset of obesity, associated with any malfunction, is observed in children. [ncbi.nlm.nih.gov]

Acute Flaccid Myelitis

Children with AFM have acute (rapid) onset of flaccid (floppy) paralysis, usually in an arm or leg. They may also have trouble moving their face or trouble swallowing. [chop.edu]

It is characterized by rapid onset of flaccid weakness in one or more limbs and distinct abnormalities of the spinal cord gray matter as seen on MRI. [medscape.com]

Rapid [3] Causes Generally unknown [4] Diagnostic method Medical imaging, nerve conduction studies, cerebral spinal fluid testing [3] [5] Differential diagnosis Transverse [en.wikipedia.org]

Hyposphagma

Treatment of the underlying disease and of DIC with rapid onset of total remission lead to resorption of the conjunctival haemorrhages and fast reduction of the retinal detachment [karger.com]

Anaesthetic Induction Agent

Pharmacokinetic properties • Rapid onset in one arm-brain circulation time • Rapid redistribution to vessel rich tissue •Rapid clearance and metabolism •No active metabolites [slideshare.net]

onset Yes No Yes Yes Rapid recovery Yes No Yes Yes Side effects Pain on injection No No Yes Yes Unwanted movements No Yes Yes No Respiratory or cardiovascular depression [pharmaceutical-journal.com]

onset, shorter elimination half life (2-4hrs) & steeper dose-response curve than other benzodiazepines. [ozemedicine.com]

Solar Retinopathy

Inhalation of poppers provides rapid-onset, short-acting euphoria and myorelaxation. [ncbi.nlm.nih.gov]

Early-Onset Generalized Torsion Dystonia

Rapid-onset dystonia-parkinsonism. Neurology, 43(12), 2596-2602. Rapid-onset dystonia-parkinsonism. / Dobyns, W. B.; Ozelius, L. J.; Kramer, P. [indiana.pure.elsevier.com]

DYSTONISCHE PARKINSONISME RAPID-ONSET DYSTONIA PARKINSONISM Zie ook: SCHEEFHALS TORTICOLLIS SPASMODIC TORTICOLLIS TORTICOLLIS SPASMODICA WRY NECK CERVICALE DYSTONIE CERVICAL [catsclem.nl]

Rapid-onset dystonia-parkinsonism in a second family. [scielo.br]

Corticobasal Degeneration

Enhanced rapid-onset cortical plasticity in CADASIL as a possible mechanism of preserved cognition. Cereb Cortex. 2011 Dec;21(12):2774-87. [medizin.uni-muenster.de]

15q13.3 Microdeletion Syndrome

Genetic evaluation and sleep studies ruled out other disorders associated with rapid-onset obesity including Prader-Willi syndrome and Rapid-onset Obesity with Hypothalamic [cureus.com]

Published: 10 March 2016 Issue Date: November 2016 DOI: https://doi.org/10.1038/gim.2016.9 Keywords autistic disorder behavior 15q13.3 deletion neurodevelopment Further reading Rapid-Onset [nature.com]

We describe the case of a pediatric patient with CHRNA7 15q13.3 microdeletion with morbid obesity of rapid-onset due to impulsive food-seeking behavior. [cureus.com]

Rocuronium Bromide

Compared with succinylcholine, this product has a relatively rapid onset as well as a significantly prolonged clinical duration of action. [chemicalbook.com]

BACKGROUND: Rocuronium bromide (ORG 9426) is a new nondepolarizing muscle relaxant with a rapid onset but an intermediate duration of action. [ncbi.nlm.nih.gov]

BACKGROUND: Rocuronium bromide, a steroid nondepolarizing muscle relaxant, has a rapid onset and an intermediate duration of action in infants, children and adults. [ncbi.nlm.nih.gov]

Infantile Dystonia - Parkinsonism

Rapid-onset dystonia-parkinsonism. Neurology. 1993;43:2596–602. [bmcneurol.biomedcentral.com]

PMID: 9546335 Possible sporadic rapid-onset dystonia-parkinsonism. Linazasoro G, Indakoetxea B, Ruiz J, Van Blercom N, Lasa A. Linazasoro G, et al. [pubmed.ncbi.nlm.nih.gov]

ATP1A3 is no stranger to the field of neurogenetics, as mutations in this gene are known to cause rapid-onset dystonia-parkinsonism ( DYT12 ). [epilepsygenetics.net]

Anaphylaxis

Anaphylaxis is a serious, rapid-onset, allergic reaction that may cause death. [ncbi.nlm.nih.gov]

Anaphylaxis is defined as a systemic, rapid onset, and potentially fatal hypersensitivity reaction, with variable clinical manifestations and severity resulting from the sudden [scielo.org.co]

Anaphylaxis is a serious allergic or hypersensitivity reaction, which is rapid in onset and sometimes can prove fatal. [ncbi.nlm.nih.gov]

Connatal Pelizaeus-Merzbacher Disease

Transitional and adult subtypes have a later onset and less severe symptomatology. [hon.ch]

The congenital form has similar characteristics but presents early in infancy and features rapid disease progression. [hon.ch]

Nondepolarizing Neuromuscular Blocker

intermediate DOA - rapid onset -> used for intubation What is the only depolarizing neuromuscular blocker in use? What is the MOA for succinylcholine? [quizlet.com]

More rapid, less intense effect at laryngeal muscles (vocal cords) then at adductor pollicis (peripheral muscle example) More rapid laryngeal muscle onset is probably due [pharmacology2000.com]

More rapid, less intense at laryngeal muscles (vocal cords) then at adductor pollicis (peripheral muscle example) more rapid laryngeal muscle onset: probably due to more [163.178.103.176]

Acute Dacryoadenitis

In case of an acute one, there is unilateral and severe pain, redness and pressure in the supratemporal region of the orbit and rapid onset is always present. [ic.steadyhealth.com]

History Acute dacryoadenitis is characterized by the following: Unilateral, severe pain, redness, and pressure in the supratemporal region of the orbit Rapid onset (hours [emedicine.medscape.com]

Remifentanil

onset and offset), non-cumulative opioid effects and rapid recovery after cessation of administration. [ncbi.nlm.nih.gov]

Because of its unique chemical structure, remifentanil must be reconstituted; it has a rapid onset, and because of ester hydrolysis, it has a rapid rate of degradation. [ncbi.nlm.nih.gov]

BACKGROUND AND AIM OF THE WORK: Succinylcholine is still included as drugs favored by anesthetists because of its rapid onset and short duration of action. [ncbi.nlm.nih.gov]

Tropical Ulcer

There was no evidence of vasculitis to explain the rapid onset of ulceration, but necrotic changes seen in the dermis and the inflammatory cell infiltrate suggest that, associated [ncbi.nlm.nih.gov]