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189 Possible Causes for Rapid Progression in Adolescence

  • Limb-Girdle Muscular Dystrophy Type 2Q

    One family has shown rapid progression of the disorder in adolescence (summary by Gundesli et al., 2010).[] Muscular Findings Extramuscular findings LGMD2A CAPN3 / Calpain-3 Adolescence High to very high Moderate / rapid Proximal legs / Rectus abdominus / Peri-scapular; contractures[] Cardiomyopathy; Arrhythmia; Respiratory insufficiency; Sudden death without prior cardiac symptoms LGMD1F TMPO3/Transportin-3 Young child- to adulthood Normal to mildly high Rapid[]

  • Scoliosis

    […] curve progression in Lenke 5 or 6 adolescent idiopathic scoliosis (AIS).A retrospective review of patients who were prospectively enrolled at the initiation of brace wear[] The majority of children do not display progressive curves, though a subset of children with adolescent idiopathic scoliosis may exhibit rapid progression.[] Because the most rapid period of spinal growth is in the first 5 years of life, and then at adolescence, these are the two times when the congenital curvature must be monitored[]

  • Polycystic Ovary Syndrome

    However, it is indicated if clinical findings are suggestive of a virilizing tumor (eg, rapid progression, clitoromegaly, pelvic mass, or a total testosterone level 200 ng[] […] adrenocorticotropic hormone test is recommended to confirm the diagnosis of NCCAH. 74 Pelvic ultrasonography is seldom necessary for diagnosis because criteria for PCOM in adolescence[]

  • Proteus

    Warady BA, Abraham AG, Schwartz GJ, Wong CS, Muñoz A, Betoko A, Furth S: Predictors of rapid progression of glomerular and nonglomerular kidney disease in children and adolescents[] As with other disease manifestations, this can progress with startling rapidity.[] Bullous pulmonary disease is uncommon but does affect some individuals with PS [ Lim et al 2011 ], most commonly in late childhood or adolescence.[]

  • Hypertrophic Cardiomyopathy

    Although the rate of progression of the disease is believed to be more rapid in children, adolescents (particularly during the teenage growth years 43 ), and young adults,[] rapid progression may also be encountered in the adult population of patients.[]

  • Familial Papillary Thyroid Carcinoma with Papillary Renal Cell Carcinoma

    The course of the disease is characterized by rapid early development, followed by slow progressive growth of adipose deposits in and around the face, neck, occipital region[] Clinical description MSL generally occurs in mid- to late-adulthood (30-60 years of age), but cases in childhood, adolescence and in elderly have also been reported.[]

  • Diabetes Mellitus Type 1

    It is manifested by the sudden onset of severe hyperglycemia, rapid progression to diabetic ketoacidosis, and death unless treated with insulin.[] Diabetes mellitus characterized by insulin deficiency, sudden onset, severe hyperglycemia, rapid progression to ketoacidosis, and death unless treated with insulin.[] Subtype of diabetes mellitus that is characterized by insulin deficiency; it is manifested by the sudden onset of severe hyperglycemia, rapid progression to diabetic ketoacidosis[]

  • Chronic Kidney Disease

    Predictors of Rapid Progression of Glomerular and Nonglomerular Kidney Disease in Children and Adolescents: The Chronic Kidney Disease in Children (CKiD) Cohort.[] Warady BA, Abraham AG, Schwartz GJ, Wong CS, Munoz A, Betoko A, Mitsnefes M, Kaskel F, Greenbaum LA, Mak RH, Flynn J, Moxey-Mims MM, Furth S (2015) Predictors of rapid progression[] […] of glomerular and nonglomerular kidney disease in children and adolescents: the chronic kidney disease in children (CKiD) Cohort.[]

  • Kyphoscoliosis

    Progression of the curve was most rapid during the adolescent growth spurt and stopped only at skeletal maturity.[] Progression was most rapid and the magnitude of the curve was the greatest in type-III kyphosis (twelve patients) followed by type-I kyphosis due to a posterolateral quadrant[]

  • Drug Dependence

    Rapid progression to regular cigarette smoking among nonsmoking adolescents: interactions with gender and ethnicity.[]

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