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63 Possible Causes for Rapid Progression to Disability, Slurred Speech

  • Transient Ischemic Attack

    Rapid recognition and response is essential to reduce the risk of disability and death. 4,8,10 As the American Heart Association/American Stroke Association (AHA/ASA) points[] We presented a 14-year-old patient with signs suggestive of transient ischemic attack (TIA), including triple episodic weakness on the right upper limb, slurred speech, and[] […] or slurred speech, and localized weakness of… Read More[]

  • Primary Progressive Multiple Sclerosis

    Although progression is more rapid, age-related disability milestones are identical to relapsing-onset disease.[] A previous analysis of the British Columbia MS database challenged the view that disability progression is rapid in PPMS, but identified few predictors of disease progression[] , for which prognosis is considered as poor due to the relatively rapid development of advanced disability as compared with RRMS.[]

  • Amyotrophic Lateral Sclerosis

    One woman with ALS received intracranial injection of adult olfactory ensheathing glia (OEG) transplantation and her disease progressed at a more rapid rate after the procedure[] speech, stumbling, and muscle twitching for 3 years.[] The earliest symptoms of Lou Gehrig's Disease may include: Tripping and falling Hand weakness or clumsiness Weakness in your leg, feet or ankles Slurred speech or trouble[]

  • Multiple Sclerosis

    progression of disability, more frequent relapses, and worse postrelapse recoveries.[] speech Fatigue Dizziness Tingling or pain in parts of your body Problems with sexual, bowel and bladder function When to see a doctor See a doctor if you experience any of[] Know the Symptoms The symptoms of MS may include tingling, numbness, painful sensations, slurred speech and blurred or double vision.[]

  • Primary Lateral Sclerosis

    Patients with more severe physical disability and a more rapid rate of disease progression had increased sensorimotor connectivity values.[] speech and drooling as the facial muscles weaken Difficulties with swallowing and breathing late in the disease Less commonly, PLS begins in your tongue or hands and then[] […] or slurred speech and drooling as facial muscles weaken PLS does not progress as quickly as ALS.[]

  • Chorea Gravidarum

    ; • Disability out of proportion to the movement disorder.[] The clinical picture is of extrapyramidal symptoms such as involuntary movements, lack of coordination and slurred speech.[] The appearance of facial grimaces slurred speech and impaired coordination may accompany this movement disorder.[]

  • Paraneoplastic Syndrome

    progression to severe disability and the absence of regeneration in a sural nerve biopsy.[] These symptoms may include difficulty in walking or swallowing, loss of muscle tone, loss of fine motor coordination, slurred speech, memory loss, vision problems, sleep disturbances[] speech or stuttering Memory loss and other thinking (cognitive) impairment Vision problems Sleep disturbances Seizures Hallucinations Unusual involuntary movements Types[]

  • Cerebellar Ataxia

    […] of symptoms Rapid Slow Postural instability and falling** Early Fast progression Worsen 20% of UPDRS scale** Late Less progression ( 10%) Progress of disability Relatively[] A 24-year-old female who was recently diagnosed with Type 1 diabetes mellitus (TiD) presented with a five-year history of visible gait disturbance and slurred speech.[] People with this disorder have a balance impairment in sitting, standing and walking, lack of co-ordination in their hands and slurred speech.[]

  • Multi-Infarct Dementia

    Most patients with worsening disability in this cohort had experienced a new stroke, indicating that recurrent stroke is a major determinant of disability progression in CADASIL[] They may also have slurred speech or language problems and suffer from physical symptoms such as dizziness, leg or arm weakness and incontinence.[] They include: Confusion and memory problems Slurred speech Language problems Abnormal behavior Lack of concentration Wandering or getting lost in familiar surroundings Moving[]

  • Spinal Demyelination

    progression to disability within several days to weeks, culminating in the need for hospital admission and aggressive therapy for an acute attack. 5 Among fulminant demyelinating[] speech The provider will perform a physical exam and ask about the symptoms, focusing on the nervous system and muscles.[] Seek immediate medical care if you experience any warning signs or symptoms, including: Sudden weakness or paralysis Sudden vision change or loss of vision Slurred speech[]

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