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11 Possible Causes for Rapid Progression to Disability, Unilateral Facial Weakness

  • Transient Ischemic Attack

    Rapid recognition and response is essential to reduce the risk of disability and death. 4,8,10 As the American Heart Association/American Stroke Association (AHA/ASA) points[journals.lww.com] […] movement 0—normal 1—minor facial weakness 2—partial facial weakness 3—complete unilateral palsy 5 Motor function (arm) 0—no drift a.[doi.org] […] similar episodes, and absence of nonspecific symptoms such as gastrointestinal distress, chest pain, or shortness of breath. 1 No one can predict which TIAs are likely to progress[journals.lww.com]

  • Primary Progressive Multiple Sclerosis

    Although progression is more rapid, age-related disability milestones are identical to relapsing-onset disease.[ncbi.nlm.nih.gov] A previous analysis of the British Columbia MS database challenged the view that disability progression is rapid in PPMS, but identified few predictors of disease progression[ncbi.nlm.nih.gov] , for which prognosis is considered as poor due to the relatively rapid development of advanced disability as compared with RRMS.[globenewswire.com]

  • Multiple Sclerosis

    progression of disability, more frequent relapses, and worse postrelapse recoveries.[dx.doi.org] Multiple Sclerosis have a higher incidence of spinal cord lesion and exhibit much more rapid development of disability than those with other forms of the disease 1 in every[themcfox.com] Relapses are associated with more rapid disability progression in SPMS but tend to occur in those at younger ages (younger than 55 years) and earlier in the disease course[doi.org]

  • Multi-Infarct Dementia

    Most patients with worsening disability in this cohort had experienced a new stroke, indicating that recurrent stroke is a major determinant of disability progression in CADASIL[functionalneurology.com] weakness, unilateral weakness of the limbs, Babinski’s sign, sensory deficit, hemianopia, and bulbar palsy were considered focal neurological signs.[doi.org] […] varied greatly among subjects and that some patients showed a marked and rapid deterioration, whereas others remained stable or even improved.[functionalneurology.com]

  • Cervical Spinal Cord Tumor

    Surgery is indicated if the diagnosis is in doubt, a tissue diagnosis is required, the spine is unstable or neurologic deterioration is severe, rapid and progressive.[aafp.org] Syringobulbia may cause vertigo, nystagmus, unilateral or bilateral loss of facial sensation, lingual atrophy and weakness, dysarthria, dysphagia, hoarseness, and sometimes[merckmanuals.com] Surgery is also indicated if decompression by radiation therapy is not expected to become effective in time to save a patient from severely disabling neurologic deficits.[aafp.org]

  • Guillain-Barré Syndrome

    A number of factors, including preceding diarrhoea, older age, rapid progression, disability at nadir and specific neurophysiological parameters have been associated with[doi.org] However, the patient developed unilateral left-sided facial weakness. She was managed with further intravenous immunoglobulin and intensive physiotherapy.[ncbi.nlm.nih.gov] progression of symptoms Severity of symptoms at their peak Table 4.[aafp.org]

  • Ptosis

    Deterioration Scale (PDS), Interview for Deterioration in Daily Living Activities in Dementia (IDDD), Disability Assessment in Dementia Scale (DADS), Functional Assessment[catsclem.nl] The presenting symptoms are unilateral facial weakness/paralysis of the facial muscles, with difficulty in closing or opening the eyelids associated with impaired taste and[journals.lww.com] Staging (FAST), Rapid Disability Rating Scale-2 BLIGHTED OVUM WINDEI ANEMBRYOTISCHE ZWANGERSCHAP ANEMBRYONIC PREGNANCY Zie ook: MISKRAAM MISCARRIAGE PREGNANCY LOSS Blighted[catsclem.nl]

  • Distal Myopathy Type 3

    It progresses slowly, with short periods of rapid muscle deterioration and weakness. Severity ranges from very mild to completely disabling.[webmd.com] EOM movements, ptosis, diplopia Facial weakness, unilateral or bilateral.[sites.google.com] Wrist and digit weakness - grip weakness, hand dexterity is affected, trouble opening bottles, caps, turning keys in clock, ignition, buttoning buttons.[sites.google.com]

  • Spinocerebellar Ataxia with Rigidity and Peripheral Neuropathy

    progression, and more severe disease in successive generations) in SCA6 compared with SCA1, SCA2, and SCA3.[jnnp.bmj.com] Unilateral facial weakness is a common feature of disease affecting the pyramidal tracts as they descend from cortex to brainstem, such as stroke.[casemed.case.edu] This leads to higher frequencies of uninformative family histories and misinterpretation of gait disturbances as disability related to old age or other disorders such as stroke[jnnp.bmj.com]

  • Marfanoid Habitus with Situs Inversus

    Progression OMIM:601170 Muscular Dystrophy, Congenital, with Severe Central Nervous System Atrophy and Absence of Large Myelinated Fibers OMIM:310200 Muscular Dystrophy,[informatics.jax.org] […] in boys Becker's Muscular Dystrophy Defective dystrophin (less severe than Duchenne's) Unilateral facial drooping Bell's Palsy Lower motor CN VII palsy (affects the whole[cram.com] Congenital, with Cerebellar Atrophy OMIM:254000 Muscular Dystrophy, Congenital, with Infantile Cataract and Hypogonadism OMIM:254100 Muscular Dystrophy, Congenital, with Rapid[informatics.jax.org]

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