Rapidly Progressive Disorder: Causes & Reasons

Possible Causes for Rapidly Progressive Disorder

Lafora disease This disorder typically presents with seizures before 20 years of age and is rapidly progressive, with death in 10 years. [epilepsydiagnosis.org]

He exhibited rapidly progressive dementia/cognitive decline, apraxia, difficult speech behavioral change, depression, confusion, ataxia (difficulty controlling muscles), and [ijnpnd.com]

These initial symptoms were followed by rapidly progressive spontaneous and induced myoclonus, convulsive seizures and death. [dusunenadamdergisi.org]

Pompe Disease

The infantile form of the disorder usually presents itself by six months of age and progresses rapidly. This form of the disorder is the most fatal. [disabilitybenefitscenter.org]

Clinical presentation varies from a rapidly fatal infantile disease to a slowly progressive late-onset myopathy frequently associated with respiratory insufficiency. [labs.gosh.nhs.uk]

progressive cardiomyopathy and was found at autopsy to have massive deposition of glycogen in the heart and skeletal muscle. 1 Pompe disease was classified as a lysosomal [doi.org]

Action Myoclonus - Renal Failure Syndrome

Lafora disease This disorder typically presents with seizures before 20 years of age and is rapidly progressive, with death in 10 years. [epilepsydiagnosis.org]

Phenytoin use aggravates the seizure disorder. [epilepsydiagnosis.org]

The disorder has been linked to mutations in the EPM2A and EPM2B genes. Lafora bodies are found in cells in most organs (neurons, liver). [epilepsydiagnosis.org]

Neuronal Ceroid Lipofuscinosis Type 7

The neuronal ceroid lipofuscinoses are a group of neurodegenerative, lysosomal storage disorders. They are inherited as an autosomal recessive pattern with the exception of adult neuronal ceroid lipofuscinosis, which can be inherited in either an autosomal recessive or an autosomal dominant manner. The neuronal[…] [ncbi.nlm.nih.gov]

Nephrotic Syndrome Type 2

AIMS: Steroid-resistant nephrotic syndrome (SRNS) is an inherent deficiency of podocyte caused by mutations of genes encoding slit diaphragm proteins. Mutations in NPHS2, encoding podocin, have been identified as responsible for childhood-onset familial SRNS. The present study revealed the genotype of a Chinese[…] [ncbi.nlm.nih.gov]

Drug-Induced Aplastic Anemia

[…] kanssa häiriö. the disease tends to progress rapidly. on taipumus edetä hyvin nopeasti. [tr-ex.me]

Aplastic anemia in children is a very serious and dangerous disease, a very high percentage of mortality among children with the disorder. hyvin suuri osa kuolleisuus lasten [tr-ex.me]

Nephritic Syndrome

Rapidly progressive glomerulonephritis (RPGN) is an acute glomerulonephritis resulting from the secondary sequelae of inflammatory (crescenteric) glomerulonephritis, of which [msdmanuals.com]

[…] that involves inflammation and changes to kidney cells) Rapidly progressive (crescentic) glomerulonephritis (a form of glomerulonephritis that leads to a rapid loss of kidney [medlineplus.gov]

[…] such as connective tissue disorders and hematologic dyscrasias (see table Causes of Glomerulonephritis). [msdmanuals.com]

Cerebro-Oculo-Facio-Skeletal Syndrome Type 1

progressive disorder, involving neuromuscular defects. [cags.org.ae]

Cerebro-oculo-facio-skeletal (COFS) syndrome is a rapidly progressive neurological disorder leading to brain atrophy with calcification, cataracts, microcornea, optic atrophy [ncbi.nlm.nih.gov]

Cerebro-oculo-facio-skeletal (COFS) syndrome is a recessively inherited rapidly progressive neurologic disorder leading to brain atrophy, with calcifications, cataracts, microcornea [ncbi.nlm.nih.gov]

Primary Oculocerebral Lymphoma

A 64‐YEAR‐OLD WOMAN WITH PROGRESSIVE DEMENTIA AND LEUKOENCEPHALOPATHY A. VitalI. [semanticscholar.org]

[…] improvement in his symptoms and flow cytometry revealed a monoclonal population of B-lymphoid cells, which is a useful tool in distinguishing malignancy from inflammatory disorders [semanticscholar.org]

Sibon Medicine, Psychology Brain pathology 2007 In a 64-year-old woman presenting with rapidly progressive dementia, brain magnetic resonance imaging revealed a diffuse leukoencephalopathy [semanticscholar.org]

Neonatal Purpura Fulminans

Abstract Purpura fulminans in neonates is a rapidly progressive thrombotic disorder manifesting as hemorrhagic skin infarction and disseminated intravascular coagulation. [ncbi.nlm.nih.gov]

progressive thrombotic disorder manifesting as hemorrhagic skin infarction and disseminated intravascular coagulation. [read.qxmd.com]

PF may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. [orpha.net]

Fetal Akinesia Sequence

Cerebro-oculo-facio-skeletal (COFS) syndrome is a rapidly progressive neurological disorder leading to brain atrophy with calcification, cataracts, microcornea, optic atrophy [scienceopen.com]

Glycogen Storage Disease Type 4

Clinically the classic Andersen disease is a rapidly progressive disorder leading to terminal liver failure unless liver transplantation is performed. [ingentaconnect.com]

Classic Andersen disease is a rapidly progressive disorder that will result in early lethality as a result of liver failure. [themedicalbiochemistrypage.org]

Creutzfeldt Jakob Disease

Meanwhile, his clinical condition progressively worsened and he developed a rapidly progressive cognitive disorder, mutism and myoclonus of the muscles. [ncbi.nlm.nih.gov]

It is a neurodegenerative disorder with characteristic clinical and diagnostic features. This disease is rapidly progressive and always fatal. [web.archive.org]

We performed CSF RT-QuIC testing in 2,141 patients who had rapidly progressive neurological disorders, determined diagnostic sensitivity and specificity in 272 cases that [ncbi.nlm.nih.gov]

Purpura Fulminans

PF may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. [orpha.net]

Homepage Rare diseases Search Search for a rare disease Disease definition A life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children [orpha.net]

Homepage Rare diseases Search Search for a rare disease Acquired purpura fulminans Disease definition Purpura fulminans (PF) is a life-threatening, rapidly progressive thrombotic [orpha.net]

Mast Cell Leukemia

Acute mast cell leukemia is a rapidly progressive disorder with leukemic mast cells in blood and in large numbers in marrow. [en.wikipedia.org]

Symptoms - Mast cell leukemia Acute mast cell leukemia is a rapidly progressive disorder with leukemic mast cells in blood and in large numbers in marrow. [checkorphan.org]

progressive disorder with leukemic mast cells in blood and in large numbers in marrow. [ipfs.io]

Intestinal Gangrene

Magnetic resonance imaging also takes longer time making its use unlikely in this rapidly progressive disorder in contrast to MDCT and angiography. [intechopen.com]

Cerebro-Oculo-Facio-Skeletal Syndrome Type 3

progressive disorder, involving neuromuscular defects. [cags.org.ae]

Rapidly progressive neurological disorder leading to brain atrophy with intracerebral calcifications, cataracts, microcornea, optic atrophy, progressive joint contractures [accessanesthesiology.mhmedical.com]

[…] and chromosomal abnormalities Other congenital malformations Mode of Inheritance Autosomal recessive Description Cerebrooculofacioskeletal Syndrome (COFS) is a lethal and rapidly [cags.org.ae]

Erb Muscular Dystrophy

Onset is between 3 and 5 years and the disorder progresses rapidly. Most boys are unable to walk by age 12, and later need a respirator to breathe. [ninds.nih.gov]

In most cases, childhood onset of LGMD results in a more severe disorder that progresses more rapidly than adolescent or adult onset cases. [rarediseases.org]

Primary Myelofibrosis

The median survival in primary myelofibrosis is 5 years from onset, but variation is wide; some patients have a rapidly progressing disorder, including development of acute [merck.com]

Prognosis: The median survival is 5 yr from the onset, but variation is wide; some patients have a rapidly progressing disorder with short survival and some have a delay in [askhematologist.com]

Platelet counts initially may be high, normal, or decreased; however, thrombocytopenia tends to supervene as the disorder progresses. [merck.com]

Rapidly Progressive Glomerulonephritis

(disorder), glomerulonephritis; rapidly progressive, rapidly progressive; glomerulonephritis, Rapidly Progressive Glomerulonephritis Italian Glomerulonefrite rapidamente [fpnotebook.com]

[…] human disease Rapidly progressive Glomerulonephritis Rapidly progressive glomerulonephritis (disorder) edit Language Label Description Also known as English rapidly progressive [wikidata.org]

progressive, rapidly progressive glomerulonephritis, Rapidly progressive glomerulonephritis, RPGN - Rapidly progressive glomerulonephritis, Rapidly progressive glomerulonephritis [fpnotebook.com]

Perry Syndrome

progressive autosomal dominant disorder with Parkinsonism, depression, weight loss, and central hypoventilation. [n.neurology.org]

DISEASE: Perry syndrome Entry H00879 Disease Name Perry syndrome Description Perry syndrome is a rapidly progressive, autosomal dominant, neurodegenerative disorder. [genome.jp]

Camilo Castañeda Cardona, Alexa Kidd, Michael Hlavac, Anthony Raizis, Michael Okun, Zbigniew Wszolek First published April 9, 2014, Abstract OBJECTIVE: Perry syndrome is a rapidly [n.neurology.org]

Acute Nephritis

SNOMED-CT } Rapidly progressive glomerulonephritis (disorder) {236392004, SNOMED-CT } [phinvads.cdc.gov]

Primary rapidly progressive glomerulonephritis This group of disorders causes microscopic damage to the glomeruli and progress rapidly. [msdmanuals.com]

progressive glomerulonephritis (crescentic glomerulonephritis) Goodpasture’s syndrome – anti-GBM antibodies against basal membrane antigens Vasculitic disorder – Wegener’ [geekymedics.com]

Fazio-Londe Disease

In conclusion, Fazio-Londe syndrome is a rapidly progressive disorder and can present at a very early age. [nature.com]

Stiff Skin Syndrome

Three years ago, 9-year-old Jaiden Rogers was diagnosed with stiff skin syndrome, a rare and rapidly progressive disorder of the connective tissue that hardens the skin and [foxnews.com]

‘Stiff Skin Syndrome’ is a rare and rapidly progressing connective tissue disorder that turns skin hard like stone. [au.news.yahoo.com]

Glomerulonephritis

Primary rapidly progressive glomerulonephritis This group of disorders causes microscopic damage to the glomeruli and progress rapidly. [msdmanuals.com]

Treating the causative disorder For rapidly progressive glomerulonephritis, suppression of the immune system For chronic glomerulonephritis, an angiotensin-converting enzyme [msdmanuals.com]

Sometimes they are caused by an infection or other treatable disorder. Kidney biopsy is required for diagnosis. The prognosis is poor. [msdmanuals.com]

Subacute Transverse Myelitis

People with symptoms of transverse myelitis may: Develop a rapidly progressive disorder with back pain, numbness, and tingling in the legs, trunk, and sometimes arms. [my.clevelandclinic.org]

People with symptoms of transverse myelitis may: develop a rapidly progressive disorder with back pain, numbness, and tingling in the legs, trunk, and sometimes arms, have [clevelandclinic.org]

In addition, some cancers may trigger an abnormal immune response that may lead to TM. 1 An acute, rapidly progressing form of TM sometimes signals the first attack of multiple [mytm.ca]

Epstein-Barr Virus-Associated Lymphoproliferative Disorder

We report a 56-year-old man undergoing autologous BMT for CML in whom a rapidly progressive lymphoproliferative disorder showing the histology of typical post-transplant lymphoproliferative [ncbi.nlm.nih.gov]

The patient subsequently developed a rapidly fatal Epstein-Barr-virus-associated lymphoproliferative disorder, clonally unrelated to the CLL. [ncbi.nlm.nih.gov]

There is, however, only one report in the English language literature of such a disorder after autografting. [ncbi.nlm.nih.gov]

Streptococcal Infection

progressive disorder that causes shock and damages internal organs). [medical-dictionary.thefreedictionary.com]

Two of the most severe invasive GAS infections are necrotizing fasciitis or flesh-eating bacteria (destruction of muscle tissue and fat) and toxic shock syndrome (a rapidly [medical-dictionary.thefreedictionary.com]

Familial Pulmonary Arterial Hypertension

About Pulmonary Arterial Hypertension Pulmonary Arterial Hypertension (PAH) is a rare and chronic, rapidly progressing disorder characterized by the constriction of small [businesswire.com]

Pulmonary arterial hypertension, until a few years ago was considered a rapidly progressive disorder, ultimately resulting in death. [lungindia.com]

Senior-Løken Syndrome Type 1

At a glance It is an inherited disorder characterized by rapidly progressive renal insufficiency (nephronophthisis) and retinitis pigmentosa. [accessanesthesiology.mhmedical.com]

Inherited disorder characterized by rapidly progressive renal insufficiency (nephronophthisis) and eye disease (retinitis pigmentosa). [accessanesthesiology.mhmedical.com]