Recurrent Fractures: Causes & Reasons

Possible Causes for Recurrent Fractures

Hereditary Hypophosphatemic Rickets with Hypercalciuria

[…] phosphorus level in patients with suspected but unexplained osteoporosis and/or recurrent renal stones. [ncbi.nlm.nih.gov]

The severe presentation of this proband in adulthood with marked nephrolithiasis, multiple fractures and low bone density emphasizes the importance of measuring the serum [ncbi.nlm.nih.gov]

Spinal Muscular Atrophy Type 2

1. Prior TW, Russman BS. Spinal muscular atrophy. NCBI Bookshelf Web site. http://www.ncbi.nlm.nih.gov/books/NBK1352/?report=printable. Updated November 14, 2013. Accessed April 15, 2016. 2. Wang CH, Finkel RS, Bertini ES, et al; and Participants of the International Conference on SMA Standard of Care. Consensus[…] [care.togetherinsma.fr]

Calvarial Doughnut Lesions - Bone Fragility Syndrome

This chapter outlines an approach to the evaluation and treatment of children with recurrent fractures and describes three common scenarios involving infants, children with [karger.com]

New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. [books.google.com]

fractures, several of which may havecraniofacial abnormalities. [docslide.net]

Osteogenesis Imperfecta Type 16

Heterozygous family members may exhibit recurrent fractures with minimal trauma, osteopenia, and blue sclerae (Keller et al., 2018; Lindahl et al., 2018). [ncbi.nlm.nih.gov]

Heterozygous family members may exhibit recurrent fractures with minimal trauma, osteopenia, and blue sclerae (Keller et al., 2018; Lindahl et al., 2018). (616229) [malacards.org]

New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. [books.google.com]

Osteogenesis Imperfecta Type 13

OI13 is characterized by normal teeth, faint blue sclerae, severe growth deficiency, borderline osteoporosis, severe bone deformity, and recurrent fractures affecting both [malacards.org]

Osteogenesis Imperfecta Type 15

Keupp et al. (2013) and Pyott et al. (2013) described osteogenesis imperfecta type XV, an autosomal recessive form of the disorder characterized by early-onset recurrent fractures [ncbi.nlm.nih.gov]

OI15 is characterized by early-onset recurrent fractures, bone deformity, significant reduction of bone density, short stature, and, in some patients, blue sclerae. [malacards.org]

Recurrent fractures Scoliosis Thin ribs Abnormality of the nervous system Cerebellar hypoplasia Global developmental delay Hypoplasia of the pons Schizencephaly Growth abnormality [ncbi.nlm.nih.gov]

Osteogenesis Imperfecta Type 5

New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. [books.google.com]

Introduction: Osteogenesis imperfecta is a rare disease leading to immobility by recurrent fractures, immobilization, short stature and muscular weakness. [bone-abstracts.org]

Type IV This may be apparent at birth with fractures or bowing of leg bones or recurrent fractures on walking. [patient.info]

Hyper-IgE Syndrome

Patients have coarse facial features, delayed shedding of baby teeth, osteopenia, and recurrent fractures. [merckmanuals.com]

Common findings among patients were recurrent fractures (in 57 percent of patients), hyperextensible joints (in 68 percent), and scoliosis (in 76 percent of patients 16 years [scienceopen.com]

Cole-Carpenter Syndrome

fractures; Scoliosis; Shallow orbits; Short stature; Vertebral compression fractures Associated Genes P4HB (Withdrawn symbols: DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB [mousephenotype.org]

Differential diagnosis OI is not the only cause of recurrent fractures among children. [orthopaedicsone.com]

fractures Increased fracture rate Increased fractures Multiple fractures Multiple spontaneous fractures Varying degree of multiple fractures [ more ] 0002757 Scoliosis 0002650 [rarediseases.info.nih.gov]

Hypophosphatasia

There is also an orthopedic procedure called, “rodding,” which has proven to be helpful for adults with recurrent fractures. [blogs.longwood.edu]

A few patients have been reported with recurrent fractures or osteoporosis but these are not considered features of the disease. [ncbi.nlm.nih.gov]

fractures, pain, respiratory problems, impaired growth and mobility, premature tooth loss, developmental delay, and seizures. [ncbi.nlm.nih.gov]

Autosomal Dominant Osteopetrosis Type 2

[…] infection, massive hemorrhage, terminal leukemia) Benign adult autosomal dominant type 50% asymptomatic Recurrent fractures Mild anemia Cranial nerve palsy (rarely) Prognosis [learningradiology.com]

On the other hand, as with osteopetrosis, the bones are brittle and prone to recurrent fractures. 20. [slideshare.net]

[…] may occur (due to thrombocytopenia) May be associated with: Renal tubular acidosis Cerebral calcification Prognosis: survival beyond middle age is uncommon (death due to recurrent [learningradiology.com]

Osteogenesis Imperfecta

Here we report a teenage girl with OI type IV, who was started on cyclical intravenous pamidronate therapy at age 6 years because of recurrent fractures. [ncbi.nlm.nih.gov]

Osteogenesis imperfecta (OI) is a group of hereditary disorders characterized by low bone mass and recurrent fractures. [ncbi.nlm.nih.gov]

The clinical phenotypes of the patient included recurrent fractures, muscle weakness, bone deformity, macrocephaly and elbow contractures, but no blue sclera or dentinogenesis [ncbi.nlm.nih.gov]

Osteopetrosis

recurrent fractures; - type I: sclerosis of the cranial vault; - type II: - rugger jersey spine and pelvic endobones; - defects in the chloride channel (CLCN7 gene) - spine [wheelessonline.com]

Patients with adult osteopetrosis are often diagnosed incidentally by Xray or on the presence of recurrent fractures. [pure.au.dk]

On the other hand, as with osteopetrosis, the bones are brittle and prone to recurrent fractures. 20. [slideshare.net]

Spondylo-Ocular Syndrome

New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. [books.google.com]

A Practical Approach to Children with Recurrent Fractures. Endocrine Development, 28, 210-225. [sydney.edu.au]

Diagnosis of Recurrent Fracture in a Pediatric Cohort. Calcified Tissue International, 103(5), 529-539. [sydney.edu.au]

Schimmelpenning-Feuerstein-Mims Syndrome

Case Reports doi: 10.1159/000070948. Affiliations PMID: 12835555 DOI: 10.1159/000070948 Case Reports Schimmelpenning-Feuerstein-Mims syndrome with hypophosphatemic rickets M Zutt et al. Dermatology. 2003. Abstract The Schimmelpenning-Feuerstein-Mims syndrome (SFM syndrome) is a rare and variable multisystem defect[…] [pubmed.ncbi.nlm.nih.gov]

Ehlers-Danlos Syndrome Spondylodysplastic Type 1

[…] delay 0001270 Proptosis Bulging eye Eyeballs bulging out Prominent eyes Prominent globes Protruding eyes [ more ] 0000520 Radioulnar synostosis Fused forearm bones 0002974 Recurrent [rarediseases.info.nih.gov]

Familial Otosclerosis

Osteogenesis imperfecta (OI) is a genetic disorder characterized by recurrent fractures, blue sclera, and varying degrees of hearing impairment; and is a known risk factor [pubmed.ncbi.nlm.nih.gov]

NEMO Mutation with Immunodeficiency

Patients with the NEMO syndrome should also be monitored for bone health, as patients with NEMO syndrome may be less able to make strong bones, though recurrent fractures [primaryimmune.org]

Congenital Disorder of Glycosylation Type 2B

Sandrine Dubois4, Vassili Valayannopoulos4, Eliane Depondt5, Chris Ottolenghi6 & […] Daniel Rabier6 Chapter 848 Accesses Résumé Les anomalies congénitales de glycosylation ou CDG (Congenital Disorders of Glycosylation) forment une classe d’erreurs innées du métabolisme, affectant la synthèse des glycannes des[…] [link.springer.com]

Exudative Vitreoretinopathy Type 1

Permanent link CopyPermanent link http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4729397 Other title The familial exsudative vitreoretinopathy (en) Author URVOY, M; LE CALLONNEC, A; TOULEMONT, P. J; ROPERT, P CHRU Rennes, serv. ophtalmologie, 35033 Rennes, France Source Ophtalmologie[…] [pascal-francis.inist.fr]

Dent Disease Type 1

Note : les liens hypertextes menant vers d'autres sites ne sont pas mis à jour de façon continue. Il est possible qu'un lien devienne introuvable. Veuillez alors utiliser les outils de recherche pour retrouver l'information désirée. Bibliographie Mayo Foundation for Medical Education and Research (Ed). Diseases &[…] [passeportsante.net]

X-Linked Recessive Hypophosphatemic Rickets

Id: lil-709213 LILACS-Express Autor: Velásquez-Jones, Luis; Medeiros-Domingo, Mara. Título: Raquitismos hipofosfatémicos hereditarios / Hereditary hypophosphatemic rickets Fonte: Bol. méd. Hosp. Infant. Méx;70(6):421-431, nov.-dic. 2013. tab. Idioma: es. Resumo: Los raquitismos hipofosfatémicos hereditarios (RHH) son un[…] [bases.bireme.br]

Vitamin D-Dependent Rickets Type 1B

Autores/as Luís Alberto Chamorro Noceda Servicio de Pediatría, Hospital Central, Instituto de Previsión Social. Asunción, Paraguay. Marta Duarte Servicio de Pediatría, Hospital Central, Instituto de Previsión Social. Asunción, Paraguay. DOI: https://doi.org/10.31698/ped.45022018008 Palabras clave: Raquitismo, deficiencia[…] [revistaspp.org]

Vitamin D-Dependent Rickets Type 2A

CLCN-Related Osteopetrosis

Fractures and arthritis require specialized treatment and follow-up since there is usually a delay in consolidation, osteomyelitis, and recurrent fractures. [scielo.org.mx]

Osteogenesis imperfecta

Some individuals have bowing of the bones in the legs and recurrent fractures, whereas others are asymptomatic. [rarediseases.org]

In OI type IV most fractures occur during childhood but women often have a recurrence of fractures after menopause. [orthop.washington.edu]

Differential Diagnosis A variety of disorders may present with recurrent fractures due to bone fragility- that is, not everyone with fractures has OI. [oif.org]

Suárez-Stickler Syndrome

[…] in the skull, dentinogenesis imperfecta, recurrent bone fractures, hypertelorism, and eye puffiness.[1][2] This disorder is unique from osteogenesis imperfecta because of [wikiwand.com]

Wormian bone-multiple fractures-dentinogenesis imperfecta-skeletal dysplasia syndrome is a rare genetic bone disorder which is characterized by the presence of wormian bones [wikiwand.com]

Grange Syndrome

Recurrent fractures Abnormality of the nervous system Intellectual disability Growth abnormality Decreased body weight IMPORTANT NOTE: NIH does not independently verify information [ncbi.nlm.nih.gov]

Recurrent fractures MedGen UID: 42094 •Concept ID: C0016655 • Injury or Poisoning The repeated occurrence of bone fractures (implying an abnormally increased tendency for [ncbi.nlm.nih.gov]

[…] artery stenosis Renal artery stenosis Abnormality of the genitourinary system Renovascular hypertension Abnormality of the musculoskeletal system Increased susceptibility to fractures [ncbi.nlm.nih.gov]

Blue Sclera

Case summary A 5-year-old boy was presented with a recurrent history of fractures since the age of 3 years. [ncbi.nlm.nih.gov]

Her daughter aged 8 years had a similar appearance of the eye with recurrent fractures since childhood without any other congenital deformity. [ijo.in]

recurrent fracture,contussions,have effective treatment in homeopathy 0 Reply [dailyrounds.org]

Fibrogenesis Imperfecta Ossium

There is progressive pain, recurrent fractures, and then weakness, muscle atrophy, and contractures. Patients become immobilized and debilitated. [oncohemakey.com]

PMID: 8781045 A Practical Approach to Children with Recurrent Fractures. Korula S, Titmuss AT, Biggin A, Munns CF. Korula S, et al. [pubmed.ncbi.nlm.nih.gov]