Recurrent-fractures: Causes & Reasons

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Possible Causes for recurrent fractures

Vitamin D Deficiency

Hyperparathyroidism can become apparent early in its course when a patient presents with symptoms of abdominal pain, recurrent renal calculi, repeated fractures, or behavior [ncbi.nlm.nih.gov]

Manias K, McCabe D, Bishop N (2006) Fractures and recurrent fractures in children; varying effects of environmental factors as well as bone size and mass. [doi.org]

Fracture prevention with vitamin D supplementation: A meta-analysis of randomized controlled trials. JAMA, 293 (18), 2257–2264. Review. [womenshealthnetwork.com]

Osteoporosis

We hypothesize that overexpression of bone morphogenetic protein 2 may be the underlying mechanism of osteoporosis and recurrent fractures. [ncbi.nlm.nih.gov]

Osteogenesis imperfecta (OI) is an inherited disorder with osteoporosis and recurrent fractures. [ncbi.nlm.nih.gov]

It prevents recurrent fractures and supply important nutrients to the bones. It helps in quick healing of the fractures. 2. [hariomji.com]

Systemic Mastocytosis

[…] vertebral fracture. [ard.bmj.com]

[…] reflux disease, as well as several pathologic bone fractures during the last 10 yr. [journals.lww.com]

In nine patients with osteoporosis and bisphosphonate therapy, mean lumbar spine BMD increased from 0.83 to 0.92 g/cm 2 ( 11.1%; ie, 2.05% per year) without recurrence of [ard.bmj.com]

Primary Hyperoxaluria

[…] low-trauma fractures Bone deformations with osteodystrophy Anemia Severe bone pain Skin nodules and ulcers Cardiomyopathy Cardiac conduction disturbances and heart block [uncoveringph.com]

[…] patients are in renal failure, calcium oxalate can deposit in tissues throughout the body.9,14 Signs of systemic oxalosis include the following14,15: Stunted bone growth Recurrent [uncoveringph.com]

Primary Hyperoxaluria Type 1

fractures 58 31 frequent (33%) Frequent (79-30%) HP:0002757 10 reduced visual acuity 58 31 frequent (33%) Frequent (79-30%) HP:0007663 11 peripheral neuropathy 58 31 frequent [malacards.org]

[…] frequent (33%) Frequent (79-30%) HP:0002910 7 hematuria 58 31 frequent (33%) Frequent (79-30%) HP:0000790 8 nephrocalcinosis 58 31 frequent (33%) Frequent (79-30%) HP:0000121 9 recurrent [malacards.org]

Calvarial Doughnut Lesions - Bone Fragility Syndrome

New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. [books.google.com]

This chapter outlines an approach to the evaluation and treatment of children with recurrent fractures and describes three common scenarios involving infants, children with [karger.com]

fractures, several of which may havecraniofacial abnormalities. [docslide.net]

Primary Hyperoxaluria Type 2

fractures 58 31 frequent (33%) Frequent (79-30%) HP:0002757 10 reduced visual acuity 58 31 frequent (33%) Frequent (79-30%) HP:0007663 11 peripheral neuropathy 58 31 frequent [malacards.org]

Primary Hyperoxaluria Type 3

fractures 58 31 frequent (33%) Frequent (79-30%) HP:0002757 10 reduced visual acuity 58 31 frequent (33%) Frequent (79-30%) HP:0007663 11 peripheral neuropathy 58 31 frequent [malacards.org]

Hyper-IgE Syndrome

Patients have coarse facial features, delayed shedding of baby teeth, osteopenia, and recurrent fractures. [msdmanuals.com]

Common findings among patients were recurrent fractures (in 57 percent of patients), hyperextensible joints (in 68 percent), and scoliosis (in 76 percent of patients 16 years [scienceopen.com]

[…] sinopulmonary infections joint hyperextensibility decreased bone mineral density recurrent fractures eczema, severe recurrent skin abscesses recurrent Staphylococcus aureus [humpath.com]

Cole-Carpenter Syndrome

fractures; Scoliosis; Shallow orbits; Short stature; Vertebral compression fractures Associated Genes P4HB (Withdrawn symbols: DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB [mousephenotype.org]

fractures Increased fracture rate Increased fractures Multiple fractures Multiple spontaneous fractures Varying degree of multiple fractures [ more ] 0002757 Scoliosis 0002650 [rarediseases.info.nih.gov]

[…] hydrocephalus; Coronal craniosynostosis; Frontal bossing; High pitched voice; Hydrocephalus; Microdontia; Micrognathia; Midface retrusion; Orbital craniosynostosis; Osteopenia; Recurrent [mousephenotype.org]

Common Cold

Patients with HIES typically also have eczema, distinct facial features, and a tendency to experience bone fractures. [tools.wmflabs.org]

People with autosomal dominant hyper-immunoglobulin E syndrome (HIES) have recurrent bacterial infections of the skin and lungs. [tools.wmflabs.org]

Osteogenesis Imperfecta

Here we report a teenage girl with OI type IV, who was started on cyclical intravenous pamidronate therapy at age 6 years because of recurrent fractures. [ncbi.nlm.nih.gov]

Osteogenesis imperfecta (OI) is a group of hereditary disorders characterized by low bone mass and recurrent fractures. [ncbi.nlm.nih.gov]

The clinical phenotypes of the patient included recurrent fractures, muscle weakness, bone deformity, macrocephaly and elbow contractures, but no blue sclera or dentinogenesis [ncbi.nlm.nih.gov]

Osteogenesis Imperfecta Type 15

OI15 is characterized by early-onset recurrent fractures, bone deformity, significant reduction of bone density, short stature, and, in some patients, blue sclerae. [malacards.org]

Keupp et al. (2013) and Pyott et al. (2013) described osteogenesis imperfecta type XV, an autosomal recessive form of the disorder characterized by early-onset recurrent fractures [malacards.org]

Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. [malacards.org]

Osteogenesis Imperfecta Type 5

New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. [books.google.com]

Introduction: Osteogenesis imperfecta is a rare disease leading to immobility by recurrent fractures, immobilization, short stature and muscular weakness. [bone-abstracts.org]

Type IV This may be apparent at birth with fractures or bowing of leg bones or recurrent fractures on walking. [patient.info]

Osteogenesis Imperfecta Type 16

New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. [books.google.com]

Heterozygous family members may exhibit recurrent fractures with minimal trauma, osteopenia, and blue sclerae (Keller et al., 2018; Lindahl et al., 2018). (616229) [malacards.org]

The effect of the deformity on functional abilities and the effect of recurrent fractures on quality of life must be considered. [online.boneandjoint.org.uk]

Osteogenesis Imperfecta Type 13

OI13 is characterized by normal teeth, faint blue sclerae, severe growth deficiency, borderline osteoporosis, severe bone deformity, and recurrent fractures affecting both [malacards.org]

Cystitis

[…] of developmental coxa vara after surgery. 61 Bian Z...Wang QQ 31489041 2019 14 The Community Orthopaedic Surgeon Taking Trauma Call: Pediatric Femoral Neck Fracture Pearls [malacards.org]

This occurred with trauma to pathologic fracture in the femur with fibrous dysplasia. [eoj.eg.net]

Pasteurized Autograft and Intramedullary Vascularized Fibular Transfer for Osteosarcoma of the Femoral Diaphysis. 61 Liu T...Guo X 31663287 2019 13 Analyzing risk factors for recurrence [malacards.org]

Hypersensitivity

Patients treated with a pacemaker have fewer syncopal attacks but may experience a recurrence rate as high as 16% in 4 years. [emedicine.medscape.com]

Patients with HIES typically also have eczema, distinct facial features, and a tendency to experience bone fractures. [niaid.nih.gov]

Mortality/Morbidity CSH is associated with an increased risk of falls, drop attacks, bodily injuries, and fractures in elderly patients. [emedicine.medscape.com]

Pathological Fracture

KEYWORDS: Adjuvant; Curettage; GCT; Giant cell tumour; Local recurrence; Pathologic fracture; Wide resection [ncbi.nlm.nih.gov]

KEYWORDS: Amputation; Event-free survival; Limb salvage; Local recurrence; Osteosarcoma; Pathological fracture [ncbi.nlm.nih.gov]

At the 1-year follow-up visit, the patient did not have any complaints, and the radiographs indicated the consolidation of the fracture without recurrence of cyst. [ncbi.nlm.nih.gov]

Hypophosphatasia

A few patients have been reported with recurrent fractures or osteoporosis but these are not considered features of the disease. [ncbi.nlm.nih.gov]

There is also an orthopedic procedure called, “rodding,” which has proven to be helpful for adults with recurrent fractures. [blogs.longwood.edu]

fractures, pain, respiratory problems, impaired growth and mobility, premature tooth loss, developmental delay, and seizures. [ncbi.nlm.nih.gov]

Autosomal Dominant Osteopetrosis Type 2

[…] infection, massive hemorrhage, terminal leukemia) Benign adult autosomal dominant type 50% asymptomatic Recurrent fractures Mild anemia Cranial nerve palsy (rarely) Prognosis [learningradiology.com]

fractures Increased fracture rate Increased fractures Multiple fractures Multiple spontaneous fractures Varying degree of multiple fractures [ more ] 0002757 Short distal [rarediseases.info.nih.gov]

[…] may occur (due to thrombocytopenia) May be associated with: Renal tubular acidosis Cerebral calcification Prognosis: survival beyond middle age is uncommon (death due to recurrent [learningradiology.com]

Sexually Transmitted Disease

Patients with HIES typically also have eczema, distinct facial features, and a tendency to experience bone fractures. [niaid.nih.gov]

People with autosomal dominant hyper-immunoglobulin E syndrome (HIES) have recurrent bacterial infections of the skin and lungs. [niaid.nih.gov]

Exostosis

Sometimes these occur after surgery, radiation or certain fracture types, and they form the most common type of benign radiation-induced tumors. [news-medical.net]

Any remnants of cartilage from the cap or any perichondrium post-operatively may contribute to recurrence of the lesions in approximately 2-5% cases [18]. [ijsronline.net]

Recurrence sometimes happens. The risk of a cancer is low, about 1%. Another type of exostosis is found in the condition called hereditary multiple exostoses (HME). [news-medical.net]

Heelspur

Radiological proof helps exclude other conditions like arthritis, stress fractures etc. [physiotherapy-treatment.com]

There is a risk of foot cramps, stress fractures, tendonitis, and instability if the plantar fascia is released. 3. [findatopdoc.com]

In addition, with plantar fascia release, there is risk of instability, foot cramps, stress fracture, and tendinitis. [webmd.com]

Ganglion Cyst

The optimal treatment of symptomatic intraosseous ganglia is surgical excision by curettage followed by bone grafting to prevent recurrence and the risk of collapsing fracture [spandidos-publications.com]

Fracture

We report a case of stapes fracture secondary to ear pick penetration into the middle ear with a pneumolabyrinth that caused a recurrent paroxysmal positional vertigo (PPV [ncbi.nlm.nih.gov]

At the same time, children with disabilities are at an increased risk of being maltreated. 82 – 84 When multiple or recurrent fractures occur in a disabled child, a trial [pediatrics.aappublications.org]

We hereby report a case of a 58-year-old female patient who developed recurrent knee pain during the third year after total knee arthroplasty. [ncbi.nlm.nih.gov]

Malnutrition

Malunion of this fracture is most common for several reasons: First, failure to reduce the fracture completely. [jamanetwork.com]

Second, recurrence of deformity after apparent reduction and confirmation by the roentgenogram. Third, excessive comminution with radial shortening. [jamanetwork.com]

Sinusitis

Patients with HIES typically also have eczema, distinct facial features, and a tendency to experience bone fractures. [niaid.nih.gov]

People with autosomal dominant hyper-immunoglobulin E syndrome (HIES) have recurrent bacterial infections of the skin and lungs. [niaid.nih.gov]

Food Allergy

Patients with HIES typically also have eczema, distinct facial features, and a tendency to experience bone fractures. [niaid.nih.gov]

People with autosomal dominant hyper-immunoglobulin E syndrome (HIES) have recurrent bacterial infections of the skin and lungs. [niaid.nih.gov]

Osteogenesis Imperfecta Type 2

fractures no cure for disease Prevention screening for mutation in family members prenatal screening with chorionic villus sampling Complications recurrent fractures leads [medbullets.com]

Type IV This may be apparent at birth with fractures or bowing of leg bones or recurrent fractures on walking. [patient.info]

fractures Increased fracture rate Increased fractures Multiple fractures Multiple spontaneous fractures Varying degree of multiple fractures [ more ] 0002757 Scoliosis Abnormal [rarediseases.info.nih.gov]