Vitamin D Deficiency
Hyperparathyroidism can become apparent early in its course when a patient presents with symptoms of abdominal pain, recurrent renal calculi, repeated fractures, or behavior[ncbi.nlm.nih.gov]
Manias K, McCabe D, Bishop N (2006) Fractures and recurrent fractures in children; varying effects of environmental factors as well as bone size and mass.[doi.org]
Fracture prevention with vitamin D supplementation: A meta-analysis of randomized controlled trials. JAMA, 293 (18), 2257–2264. Review.[womenshealthnetwork.com]
Osteoporosis
We hypothesize that overexpression of bone morphogenetic protein 2 may be the underlying mechanism of osteoporosis and recurrent fractures.[ncbi.nlm.nih.gov]
Osteogenesis imperfecta (OI) is an inherited disorder with osteoporosis and recurrent fractures.[ncbi.nlm.nih.gov]
The HORIZON Recurrent Fracture Trial: design of a clinical trial in the prevention of subsequent fractures after low trauma hip fracture repair.[dx.doi.org]
Primary Hyperoxaluria
Summary Epidemiology The prevalence of PH1 reported in Europe ranges from 1/333,000 - 1/1,000,000. Higher values are reported in specific populations with a high rate of consanguinity. Clinical description There exists an important heterogeneity in the clinical presentation and onset of PH1. The severe infantile form is[…][orpha.net]
Calvarial Doughnut Lesions - Bone Fragility Syndrome
New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included.[books.google.com]
This chapter outlines an approach to the evaluation and treatment of children with recurrent fractures and describes three common scenarios involving infants, children with[karger.com]
fractures, several of which may havecraniofacial abnormalities.[docslide.net]
Cole-Carpenter Syndrome
fractures Increased fracture rate Increased fractures Multiple fractures Multiple spontaneous fractures Varying degree of multiple fractures [ more ] 0002757 Scoliosis Abnormal[rarediseases.info.nih.gov]
Prenatal growth deficiency Prenatal growth retardation [ more ] 0001511 Kyphosis Hunched back Round back [ more ] 0002808 Muscular hypotonia Low or weak muscle tone 0001252 Recurrent[rarediseases.info.nih.gov]
Autosomal Dominant Hyper-IgE Syndrome
Common findings among patients were recurrent fractures (in 57 percent of patients), hyperextensible joints (in 68 percent), and scoliosis (in 76 percent of patients 16 years[scienceopen.com]
Patients have coarse facial features, delayed shedding of baby teeth, osteopenia, and recurrent fractures.[msdmanuals.com]
[…] sinopulmonary infections joint hyperextensibility decreased bone mineral density recurrent fractures eczema, severe recurrent skin abscesses recurrent Staphylococcus aureus[humpath.com]
Common Cold
Patients with HIES typically also have eczema, distinct facial features, and a tendency to experience bone fractures.[tools.wmflabs.org]
People with autosomal dominant hyper-immunoglobulin E syndrome (HIES) have recurrent bacterial infections of the skin and lungs.[tools.wmflabs.org]
Osteogenesis Imperfecta
Here we report a teenage girl with OI type IV, who was started on cyclical intravenous pamidronate therapy at age 6 years because of recurrent fractures.[ncbi.nlm.nih.gov]
Osteogenesis imperfecta (OI) is a group of hereditary disorders characterized by low bone mass and recurrent fractures.[ncbi.nlm.nih.gov]
The clinical phenotypes of the patient included recurrent fractures, muscle weakness, bone deformity, macrocephaly and elbow contractures, but no blue sclera or dentinogenesis[ncbi.nlm.nih.gov]
Osteogenesis Imperfecta Type 5
New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included.[books.google.com]
Introduction: Osteogenesis imperfecta is a rare disease leading to immobility by recurrent fractures, immobilization, short stature and muscular weakness.[bone-abstracts.org]
Type IV This may be apparent at birth with fractures or bowing of leg bones or recurrent fractures on walking.[patient.info]
Osteogenesis Imperfecta Type 15
OI15 is characterized by early-onset recurrent fractures, bone deformity, significant reduction of bone density, short stature, and, in some patients, blue sclerae.[malacards.org]
Keupp et al. (2013) and Pyott et al. (2013) described osteogenesis imperfecta type XV, an autosomal recessive form of the disorder characterized by early-onset recurrent fractures[malacards.org]
Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality.[malacards.org]