Recurrent Infection: Causes & Reasons

Possible Causes for Recurrent Infection

Recurrent infections Permanent damage to the bronchi may occur, resulting in bronchiectasis. [emedicine.medscape.com]

George is a 2 year old male brought in by his parents Wiskott and Aldrich because of concerns about recurrent infections. [slideshare.net]

Some will suffer recurrent infections from infancy. [immunodeficiency.ca]

Congenital Neutropenia

Recurrent and severe infections should alert physicians to possible immunodeficiency disease. [ncbi.nlm.nih.gov]

Medical and dental histories revealed numerous recurrent bacterial infections associated with oral and non-oral tissues. [ncbi.nlm.nih.gov]

Herein, we describe two siblings with SCN born from consanguineous parents who were referred for complaints of recurrent cutaneous infections, gingivitis, purulent otitis [ncbi.nlm.nih.gov]

Congenital AIDS

causing recurrent chest infections in cystic fibrosis). [racgp.org.au]

[…] sinopulmonary or GI infections, candidiasis, meningitis X-linked agammaglobulinemia X-linked BTK Recurrent sinopulmonary and skin infections during infancy, transient neutropenia [msdmanuals.com]

infections. [healthdirect.gov.au]

Common Variable Immunodeficiency

When a patient suffers with recurrent pulmonary infections, bronchiectasis can develop. Patients generally suffer with weakness and severe fatigue. [xpertdox.com]

KEYWORDS: Autoimmunity; CD21(low) B cells; Chronic inflammatory diseases; Common variable immunodeficiency; Recurrent infections [ncbi.nlm.nih.gov]

Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by antibody deficiency, poor humoral response to antigens, and recurrent infections. [ncbi.nlm.nih.gov]

Hypogammaglobulinemia

Patients with hypogammaglobulinemia are susceptible to recurrent bacterial, viral, fungal, and parasitic infections. [ncbi.nlm.nih.gov]

infections. [ncbi.nlm.nih.gov]

We describe a patient with low immunoglobulin levels due to carbamazepine use who presented with recurrent urinary tract infection. [ncbi.nlm.nih.gov]

Agammaglobulinemia

Recurrent bacterial infections of the skin, lungs and the gastrointestinal tract appearing in infancy are the main clinical presentation. [symptoma.com]

[…] results in severe and recurrent infections, usually bacterial ones that are difficult to eliminate. [web.archive.org]

Diagnosis Your doctor will take a medical history to document recurrent infections and do a physical exam. [sparrow.org]

Ataxia-Telangiectasia Syndrome

infections, and cancer susceptibility. [ncbi.nlm.nih.gov]

[…] of recurrent infection. [statpearls.com]

BACKGROUND: Ataxia telangiectasia (AT) is a primary immunodeficiency associated with recurrent infections. [ncbi.nlm.nih.gov]

Primary Ciliary Dyskinesia

infections such as bronchitis and pneumonias Excess mucus Difficulty clearing mucus Chronic nasal congestion Recurrent middle ear infections Recurrent cold symptoms Abnormality [chop.edu]

infections and development of bronchiectasis with daily physiotherapy. [ncbi.nlm.nih.gov]

Primary ciliary dyskinesia is characterized by recurrent infections of the respiratory tract as...plus Disease This syndrome is characterized by recurrent infections of the [shop.labogen.com]

Chronic Granulomatous Disease

CGD may involve many organs and present with recurrent infections and inflammations. [ncbi.nlm.nih.gov]

Chronic granulomatous disease is a rare, inherited immunodeficiency disorder that reduces the superoxide generation ability of phagocytes, leading to recurrent infections [ncbi.nlm.nih.gov]

Chronic granulomatous disease is a rare primary immunodeficiency disorder, which leads to increased susceptibility to recurrent infections and severe inflammatory manifestations [ncbi.nlm.nih.gov]

Pediatric Chronic Granulomatous Disease

Chronic granulomatous disease (CGD), a rare immunodeficiency, typically presents with recurrent infections caused by catalase-positive organisms. [scholars.northwestern.edu]

Chronic granulomatous disease is a rare, inherited immunodeficiency disorder that reduces the superoxide generation ability of phagocytes, leading to recurrent infections [ncbi.nlm.nih.gov]

Lymphoproliferative Syndrome 1

Clinical features include splenomegaly, lymphadenopathy, anemia, thrombocytopenia, pancytopenia, recurrent infections. There is an increased risk for lymphoma. [uniprot.org]

[…] aphthous stomatitis ; Recurrent infections ; Splenomegaly ; Stomatitis ; Thrombocytopenia Associated Genes ITK (Withdrawn symbols: EMT, LYK, PSCTK2 ) Mouse Orthologs Itk [mousephenotype.org]

infections Cirrhosis Lymphopenia Recurrent upper respiratory tract infections Vasculitis Ascites Recurrent respiratory infections Ptosis Combined immunodeficiency Erythema [mendelian.co]

Cyclic Neutropenia

Recurrent infections, inflammation, and ulcers can lead to significant chronic morbidity. [ncbi.nlm.nih.gov]

Here we report on an exceptional CVID patient with recurrent episodes of cyclic neutropenia, skin vasculitis and recurrent infections associated with a transient, but reproducible [ncbi.nlm.nih.gov]

Patients with the disease suffer from recurrent infections at regular intervals of nearly three weeks. [ncbi.nlm.nih.gov]

Severe Combined Immunodeficiency

A 15-month-old boy presented with failure to thrive, neutropenia and recurrent infections. He was diagnosed with T-B-NK+ SCID. [ncbi.nlm.nih.gov]

Most children with SCID presented with failure to thrive and recurrent infections and there was no significant delay between presentation and diagnosis. [ncbi.nlm.nih.gov]

They develop recurrent infections and fail to thrive. [columbiadoctors.org]

Netherton Syndrome

infections. [krystalbio.com]

Other problems associated with Netherton syndrome are delayed growth and development, immune abnormalities, recurrent infections, and intermittent aminoaciduria. [ncbi.nlm.nih.gov]

Affected infants typically have delayed growth and development, immune abnormalities with recurrent infections, and intermittent aminoaciduria. [ncbi.nlm.nih.gov]

Hyper-IgE Syndrome

HIES is characterized by eczema, recurrent infections of the skin and lungs, and elevated levels of serum IgE [3]. [ajronline.org]

[…] fractures. 57 Kirchner SG...Wright PF 4011897 1985 47 Immunoglobulins in the hyperimmunoglobulin E and recurrent infection (Job's) syndrome. [malacards.org]

Other systemic infections were recurrent bacterial arthritis and staphylococcal osteomyelitis at fracture sites. [nejm.org]

Selective IgA Immunodeficiency

Many patients are asymptomatic, but some develop recurrent infections and autoimmune disorders. [merck.com]

Nevertheless, predisposition toward recurrent infections, autoimmune diseases, and allergies may be present. [symptoma.com]

Symptoms and Signs Most patients with selective IgA deficiency are asymptomatic; others have recurrent sinopulmonary infections, diarrhea, allergies (eg, asthma, associated [merck.com]

Wiskott-Aldrich Syndrome

infections with encapsulated bacteria due to immunodeficiency increased incidence of autoimmune manifestations and malignancies The incidence currently quoted is approximately [radiopaedia.org]

Ophthalmic disease was described in three patients with the Wiskott-Aldrich syndrome, an entity characterized by eczema, thrombocytopenia, and recurrent infections, and inherited [jamanetwork.com]

We investigated two Malay boys who presented with congenital thrombocytopenia, eczema and recurrent infections. [ncbi.nlm.nih.gov]

Autoimmune Lymphoproliferative Syndrome Type 3

Recurrent infections may occur in some patients. [altmeyers.org]

Some patients have recurrent infections, and there may be an increased risk of hematologic malignancy (summary by {2:Oliveira, 2013} and {1:Niemela et al., 2010}). [diseaseinfosearch.org]

Infection Syndrome, Autosomal Dominant Hies, Autosomal Dominant Hyper-IgE Syndrome, Autosomal Dominant Job Syndrome 147060 Genetic Test Registry Hyper-IgE Recurrent Infection [ukgtn.nhs.uk]

Chédiak-Higashi Syndrome

In our case, onset of disease occurs in infancy and had history of recurrent infections. [omicsgroup.org]

A 2-year-old girl presented to us with recurrent infections, hepatosplenomegaly, and photophobia. On examination she had blond hair with a metallic sheen. [thelancet.com]

Most patients undergo a variable period of recurrent infections before going into the accelerated phase. [ncbi.nlm.nih.gov]

Cartilage Hair Hypoplasia

infections usually due to cellular and/or humoral immunodeficiency. [ncbi.nlm.nih.gov]

infections. [symptoma.com]

Despite mutation homogeneity, eight (32%) patients had severe or recurrent infections, two (8%) of these children underwent bone-marrow transplantation for combined immunodeficiency [ncbi.nlm.nih.gov]

Alpha-Mannosidosis

The disease characterized by mental retardation, skeletal changes, hearing impairment, and recurrent infections. [ncbi.nlm.nih.gov]

In humans, alpha-mannosidosis results in progressive facial- and skeletal abnormalities, motor impairment, hearing impairment, intellectual disability, recurrent infections [ncbi.nlm.nih.gov]

Major symptoms include mental retardation, skeletal changes and recurrent infections. [ncbi.nlm.nih.gov]

DiGeorge Syndrome

A 2-year-old boy with chromosome 22q11.2 deletion syndrome was referred for recurrent sinopulmonary infections. [ncbi.nlm.nih.gov]

Its symptoms vary greatly between individuals but commonly include a history of recurrent infection, heart defects, and characteristic facial features. [ncbi.nlm.nih.gov]

For children diagnosed before the age of 2, recurrent infections and thymic hypoplasia were the most frequent findings, followed by hypocalcemia. [scielo.br]

Idiopathic Neutropenia

A 48-year-old woman who presented with chronic idiopathic neutropenia causing life-long recurrent infections, and postoperative suppurative wound infections, presented for [ncbi.nlm.nih.gov]

None had recurrent infections, leukemia, lupus erythematosus, or rheumatoid arthritis. [nejm.org]

In addition to a laboratory assessment, neutropenia patients may have a history of frequent/recurrent infections, lung infections, chronic ear infections, skin infections, [luriechildrens.org]

Hairy Cell Leukemia

Patients require treatment when they have significant cytopenia or recurrent infections. [ncbi.nlm.nih.gov]

The clinical features are often related to cytopenias and include recurrent infections (due to neutropenia) and weakness and fatigue (due to anemia). [webpathology.com]

Common hairy cell leukemia symptoms Symptoms of HCL may include: Weakness or feeling tired Recurrent infections and fevers Easy bruising or bleeding Shortness of breath Unexplained [cancercenter.com]

Rubinstein-Taybi Syndrome

It is estimated that approximately 75% of patients with RTS experience recurrent respiratory infections. [ncbi.nlm.nih.gov]

Respiratory system - Recurrent infections, sleep apnea, and lung lobulation, while increased susceptibility to the collapse of the larynx and breathing difficulties are also [symptoma.com]

In the present study, the humoral immune response in 16 RTS patients with recurrent respiratory infections of possible bacterial etiology was evaluated. [ncbi.nlm.nih.gov]

Dubowitz Syndrome

Eczema and recurrent infections require conservative treatment. [orpha.net]

She/he may be prone to recurrent infections, hypogammaglobulinemia, IgA deficiency, aplastic anemia, acute lymphatic leukemia, lymphoma, and/or neuroblastoma. contributor: [dubowitzsyndrome.net]

Mucopolysaccharidosis Type 2

Most patients with MPS 2 have progressive hearing loss and recurrent infections of the middle ear. [symptoma.com]

[…] ear infections Frequent ear infections 0410018 Recurrent upper respiratory tract infections Recurrent colds 0002788 Retinal degeneration Retina degeneration 0000546 Retinopathy [rarediseases.info.nih.gov]

Mucopolysaccharidosis type II is a multisystem disorder and symptoms include coarse face, short stature, skeletal abnormalities, recurrent infections, cardiomyopathy, hepatomegaly [symptoma.com]

Congenital Generalized Lipodystrophy Type 4

infections Frequent infections Frequent, severe infections Increased frequency of infection infections, recurrent Predisposition to infections Susceptibility to infection [rarediseases.info.nih.gov]

[…] umbilicus Prominent belly button Prominent navel [ more ] 0001544 Proximal muscle weakness Weakness in muscles of upper arms and upper legs 0003701 Pyloric stenosis 0002021 Recurrent [rarediseases.info.nih.gov]

Aspartylglucosaminuria

infections and diarrhea; mental retardation, seizures, coarse facial features, and skeletal abnormalities become evident by adolescence. [medical-dictionary.thefreedictionary.com]

Clincal signs and symptoms include hepatomegaly, splenomegaly, hearing loss, mental retardation, skeletal abnormalities, and recurrent respiratory infections. [icd10data.com]

infections and diarrhea; mental retardation, seizures, coarse facial features, and skeletal abnormalities that become evident by adolescence. [medical-dictionary.thefreedictionary.com]

Mohr Syndrome

In those with a contiguous gene deletion syndrome (CGS), recurrent infections may be present. [rarediseases.info.nih.gov]

If the CGS includes the Bruton agammaglobulinemia tyrosine kinase (BTK) gene, recurrent infections secondary to this X-linked agammaglobulinemia (XLA) are present. [findzebra.com]

At age 2 years, bilateral hearing loss appeared and recurrent infections led to a diagnosis of Bruton agammaglobulinemia. [n.neurology.org]