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772 Possible Causes for Recurrent Pneumonia, Splenomegaly

  • Felty's Syndrome

    Computed tomography of the pelvis led to an incorrect diagnosis of malignancy, while radionuclide imaging using Tc-99m sulfur colloid confirmed the diagnosis of ectopic splenomegaly[] We report on a 67-year-old man with Felty's syndrome (FS) complicated by recurrent pneumonia and an infected wound, which was not healing in spite of maximal antibiotic and[] Abstract The syndrome of atrophic polyarthritis occurring in an adult, associated with fever, secondary anemia, leukopenia and splenomegaly, was described by Felty 1 in 1924[]

  • Mucopolysaccharidosis 6

    Macrocephaly Enlarged tongue Prominent forehead Possible coarse texture of hair Hepatomegaly and splenomegaly are often present in patients with MPS VI.[] Patients are typically susceptible to developing obstructive and restrictive lung disease which are accompanied by complications such as recurrent pneumonia and obstructive[] Less often, the spleen may also be enlarged (splenomegaly).[]

  • Pulmonary Histoplasmosis

    Patients present with recurrent pneumonia, haemoptysis or respiratory failure.[] […] young, very old, HIV ) to liver, spleen, bone marrow, nodes, lung, rarely to skin Disseminated disease: strongly associated with AIDS; patients have fever, weight loss, splenomegaly[] In patients with underlying lung disease, particularly COPD, a subacute pneumonia can evolve into chronic pulmonary histoplasmosis and is characterized by persistent or recurrent[]

  • Non-Hodgkin Lymphoma

    During RTX/CHOP treatment, human-IgG-immunoglobulin (IVIg) therapy was introduced in six patients after recurrent infections, including community-acquired pneumonia (85.7%[] Splenomegaly is observed in approximately 40% of patients; the spleen is rarely the only involved site at presentation.[] Slow growing or indolent lymphomas usually present with lymphadenopathy, hepatomegaly, splenomegaly or different types of cytopenias.[]

  • Chronic Lymphocytic Leukemia

    In the physical examination, generalized lymphadenopathy and hepato- and/or splenomegaly may be noted.[] After 3 years, he presented a CLL progression with worsening lymphocytosis, anemia, thrombocytopenia, increased splenomegaly, and lymphadenopathies.[] ; anterior nasal bleeding; pustulous non-itching lesions at the cervical region and posterior thorax; enlarged bilateral axillary lymph nodes; hepatomegaly; and moderate splenomegaly[]

  • Histoplasmosis

    […] constitutional symptoms, namely weight loss and Karnofsky classification 30, gastrointestinal manifestations with alteration of liver enzymes and hepatosplenomegaly and/or splenomegaly[] Patients present with recurrent pneumonia, haemoptysis or respiratory failure.[] These include recurrent pneumonia , respiratory failure , fibrosing mediastinitis , superior vena cava syndrome , pulmonary vessel obstruction, progressive fibrosis of lymph[]

  • Hairy Cell Leukemia

    Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[] It typically affects middle-aged to elderly male who present with pancytopenia and massive splenomegaly. Lymphadenopathy is usually not seen.[] All patients were adults with splenomegaly.[]

  • Rheumatoid Arthritis

    It is extremely rare for RA to present as FS or develop after initially presenting as neutropaenia and splenomegaly.[] […] anti-citruillated plasma antibody (ACPA): it is more than 80% sensitive and more than 95% specific elevated ESR or C-reactive protein Associations Felty syndrome : rheumatoid arthritis, splenomegaly[] This is characterized by splenomegaly, and leukopenia – predominantly granulocytopenia.[]

  • Visceral Larva Migrans

    Follow-up showed increased physical activity, improved respiratory status, and resolution of splenomegaly.[] Clinical findings were pain, fever, anorexia, dizziness, dyspnea, weight loss, cough, hepatomegaly, splenomegaly and lymphadenopathy.[] […] larva migrans and hypereosinophilia syndrome with persistently elevated white blood cell count despite adequate medical therapy in a 4-year-old boy with leukocytosis and splenomegaly[]

  • Sickle Cell Disease

    Clinical findings are wide and include 1,6 : bone pain bone infarction subperiosteal haemorrhage osteomyelitis pulmonary acute chest syndrome recurrent pneumonia (impaired[] Sickle trait does not cause anemia, microcytosis, splenomegaly, or pain. Further, people with sickle trait can donate blood.[] , Streptococcus pneumoniae ).[]

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