Recurrent Respiratory Infection: Causes & Reasons

Possible Causes for Recurrent Respiratory Infection

All of them had clinical history of recurrent respiratory infection. Imaging analysis showed varying degrees of bronchiectasis. [ncbi.nlm.nih.gov]

respiratory infections due to PCD. [ncbi.nlm.nih.gov]

Congenital disorders of ciliary beating, referred to as primary ciliary dyskinesia (PCD), are characterized by deficient mucociliary clearance and severe, recurrent respiratory [ncbi.nlm.nih.gov]

Common Variable Immunodeficiency

Recurrent respiratory infections are the most common clinical manifestations. CVID patients can also develop various autoimmune and lymphoproliferative complications. [ncbi.nlm.nih.gov]

As the result of an inherent inability to properly defend against infection, CVID patients results in recurrent respiratory infections, both upper and lower. [mastattack.org]

respiratory infections due to common variable immunodeficiency (CVID), and systemic granulomatous disease diagnosed at a later age. [ncbi.nlm.nih.gov]

Ataxia-Telangiectasia Syndrome

Many patients have recurrent respiratory infections. Leukemia or lymphomas are seen in 10-15% of patients and may be the presenting finding. [esid.org]

Recurrent respiratory tract and sinus infections are common, frequently causing death in adolescence or young adulthood. [emedicine.com]

Mortality/Morbidity The cause of death in more than 50% of patients with ataxia-telangiectasia is recurrent respiratory infections. [emedicine.com]

Selective IgA Immunodeficiency

[…] of infection infections, recurrent Predisposition to infections Susceptibility to infection [ more ] 0002719 Recurrent respiratory infections Frequent respiratory infections [rarediseases.info.nih.gov]

Immunoglobulin levels and function in pre-school children with recurrent respiratory infections. D Isaacs, A D Webster, and H B Valman. [allergycases.blogspot.com]

Recurrent respiratory infections are common but this is by no means pathognomonic, as every GP will be aware of the 'sickly child' who seems to acquire infections from his [patient.info]

Scimitar Syndrome

It has been reported most widely in adults and older children and is usually found during a workup for dyspnea, fatigue, recurrent respiratory infections, or as an incidental [medscape.com]

Rarely, the disease may manifest with a small shunt, a cardiac murmur, and recurrent respiratory infections in children and adults. [orpha.net]

Hyper-IgE Syndrome

Signs & Symptoms These are some of the signs and symptoms: High levels of IgE in the blood Eczema Recurrent skin abscesses Severe recurrent respiratory infections that may [cpi.org.au]

AR-HIES similarly presents with eczema, skin abscesses, recurrent respiratory infections, candidiasis and other fungal infections. [primaryimmune.org]

[…] but is not associated with increased upper respiratory infections or retained primary teeth Severe combined immunodeficiency distinguishing factor often presents early in [step2.medbullets.com]

Agammaglobulinemia

Here we report a patient with recurrent respiratory tract infections and early onset agammaglobulinemia who carried a unique disease-causing intronic loss-of-function mutation [ncbi.nlm.nih.gov]

Reduced lymphoid or reticuloendothelial organs, including the tonsil, lymph nodes, spleen, adenoids and intestinal Peyer patches Recurrent respiratory infections, including [dermnetnz.org]

Measurement of serum immunoglobulins should be performed in all children with recurrent, complicated respiratory infections as a screening test for humoral immunodeficiencies [biomed.papers.upol.cz]

Primary Immune Deficiency Disorder

Coexistence of (Partial) Immune Defects and Risk of Recurrent Respiratory Infections. [clinchem.aaccjnls.org]

Recurrent respiratory infections are common but this is by no means pathognomonic, as every GP will be aware of the 'sickly child' who seems to acquire infections from his [patient.info]

In one case study from the Hacettepe University in Turkey, Kiliç et al [34] reported a 12-year-old boy who had recurrent respiratory tract infections and chronic diarrhea [emedicine.medscape.com]

X-Linked Agammaglobulinemia Type 1

respiratory infections, including otitis media, pneumonia, bronchitis or sinusitis; the most common causes are pneumococcus, streptococcus and staphylococcus. [dermnetnz.org]

Symptoms and Signs The first manifestations are often hemorrhagic (usually bloody diarrhea), followed by recurrent respiratory infections, eczema, and thrombocytopenia. [merck.com]

Presentation Most likely to be diagnosed when unusually severe or recurrent respiratory tract infections occur in a male infant. [patient.info]

Mucopolysaccharidosis Type 2

[…] ear infections Frequent ear infections 0410018 Recurrent upper respiratory tract infections Recurrent colds 0002788 Retinal degeneration Retina degeneration 0000546 Retinopathy [rarediseases.info.nih.gov]

Large tongue [ more ] 0000158 Peripheral visual field loss Loss of peripheral vision 0007994 Progressive neurologic deterioration Worsening neurological symptoms 0002344 Recurrent [rarediseases.info.nih.gov]

Mucopolysaccharidosis Type 1

respiratory infections Frequent respiratory infections Multiple respiratory infections respiratory infections, recurrent Susceptibility to respiratory infections [ more ] [rarediseases.info.nih.gov]

infections Sleep apnea Hydrocephalus Hepatosplenomegaly (enlarged liver and spleen) Umbilical hernia Inguinal hernia Hearing loss Recurrent ear infections Corneal clouding [rarediseases.info.nih.gov]

[…] more ] 0000256 Malabsorption Intestinal malabsorption 0002024 Microdontia Decreased width of tooth 0000691 Paresthesia Pins and needles feeling Tingling [ more ] 0003401 Recurrent [rarediseases.info.nih.gov]

Childhood Non-Small Cell Lung Cancer

The symptoms of childhood NSCLC are non-specific and comprise breathing difficulties, persistent cough, bloody sputum, and recurrent respiratory infections. [symptoma.com]

respiratory infection Pain in the chest, side, or back (usually due to infiltration by the tumor of areas surrounding the lungs) that sometimes worsens with taking a breath [emedicinehealth.com]

[…] primary tumor may include any of the following: Cough Shortness of breath Difficulty taking a deep breath Wheezing Coughing or spitting blood (hemoptysis) Pneumonia or other recurrent [emedicinehealth.com]

Niemann-Pick Disease Type B

This article describes a very rare presentation of NPD-B in an infant who had suffered recurrent respiratory tract infections. [ncbi.nlm.nih.gov]

Although many NPD-B patients are asymptomatic, more severely affected patients may exhibit cough, shortness of breath, and recurrent respiratory infections. 12 Cyanosis, clubbing [pediatrics.aappublications.org]

Mucopolysaccharidosis Type 4

Affected individuals may also develop numerous and recurrent respiratory infections and a thickening of the heart valves. [morquio.ca]

[…] upper respiratory tract infections Recurrent colds 0002788 Restrictive ventilatory defect Stiff lung or chest wall causing decreased lung volume 0002091 Scoliosis Abnormal [rarediseases.info.nih.gov]

respiratory infections, cardiac disease [ 32, 33 ], hepatomegaly and splenomegaly, umbilical and inguinal hernias, chronic diarrhoea, CTS [ 34 ], communicating hydrocephalus [rheumatology.oxfordjournals.org]

Cyclic Neutropenia

[…] aphthous stomatitis Recurrent canker sores 0011107 Recurrent respiratory infections Frequent respiratory infections Multiple respiratory infections respiratory infections [rarediseases.info.nih.gov]

Despite the profound cyclic neutropenia, most patients have a benign course of recurrent fever, malaise, oral ulceration, and minor skin and upper respiratory tract infections [ncbi.nlm.nih.gov]

Cyclic neutropenia is usually diagnosed in children before age 2 years based of regularly occurring fever, mouth ulcers, and recurrent skin or respiratory infections. [ashpublications.org]

Cystic Fibrosis

respiratory infections. [ncbi.nlm.nih.gov]

digestive and reproductive tracts: although lungs are normal at birth, recurrent respiratory infection is a major presenting feature 85% of CF patients have pancreatic insufficiency [gpnotebook.co.uk]

Presentation As normal digestive function is possible with The most common presentation is with respiratory problems - usually recurrent lower respiratory tract infection [patient.info]

Mucopolysaccharidosis Type 3

[…] upper respiratory tract infections Recurrent colds 0002788 Seizures Seizure 0001250 Sleep disturbance Difficulty sleeping Trouble sleeping [ more ] 0002360 Splenomegaly Increased [rarediseases.info.nih.gov]

Affected individuals often experience chronic diarrhea and recurrent upper respiratory and ear infections. [ghr.nlm.nih.gov]

Chronic Granulomatous Disease

0000388 Pyloric stenosis 0002021 Recurrent respiratory infections Frequent respiratory infections Multiple respiratory infections respiratory infections, recurrent Susceptibility [rarediseases.info.nih.gov]

The patient also had recurrent bouts of pyodermas and respiratory tract infections. [ijdvl.com]

Case Description:We report the case of a 4-year-old boy who had recurrent respiratory infections and episodes of headache. [surgicalneurologyint.com]

Hyper-IgM Syndrome Type 2

[…] bacterial infections Abnormality of the respiratory system Recurrent respiratory infections Recurrent upper and lower respiratory tract infections PubMed Costa-Carvalho BT [ncbi.nlm.nih.gov]

The most common problem in all forms of HIGM syndrome is an increased susceptibility to infection including recurrent upper and lower respiratory tract infections. [primaryimmune.org]

The most common symptoms of hyper IgM syndrome include: Increased susceptibility to bacterial and viral infections, specifically recurrent upper and lower respiratory tract [chop.edu]

Hyper-IgM Syndrome

respiratory infections secondary to deficient lgA Lymphoid hyperplasia large tonsils and palpable lymph nodes Lack of other antibody types causes compensatory B-cell proliferation [pixorize.com]

respiratory infections, or an opportunistic infection, a doctor might screen for HIGM. [myigsource.com]

The most common problem in all forms of HIGM syndrome is an increased susceptibility to infection including recurrent upper and lower respiratory tract infections. [primaryimmune.org]

Hyper-IgM Syndrome Type 5

[…] bacterial infections Abnormality of the respiratory system Recurrent upper and lower respiratory tract infections IMPORTANT NOTE: NIH does not independently verify information [ncbi.nlm.nih.gov]

The most common issue in all forms of HIGM syndrome is an increased susceptibility to infection, to include recurrent upper and lower respiratory tract infections. [disabled-world.com]

The most common problem in all forms of HIGM syndrome is an increased susceptibility to infection including recurrent upper and lower respiratory tract infections. [primaryimmune.org]

IgG Subclass Deficiency

infections. [omicsonline.org]

IgG3 deficiency is observed in viral infections of the urinary tract; IgG2 and IgG3 deficiency predisposes to recurrent respiratory tract infections [ 4 ]. [ncbi.nlm.nih.gov]

Clinical Presentations of IgG Subclass Deficiency Patients with any form of IgG subclass deficiency occasionally suffer from recurrent respiratory infections similar to the [primaryimmune.org]

Mucopolysaccharidosis Type 7

She had a history of recurrent respiratory tract infections with atopic dermatitis. [neurologyindia.com]

In common with other forms of MPS, recurrent otitis media and respiratory infections are seen, more so in persons with significant and early disease. [journals.lww.com]

Atrial Septal Defect

Common symptoms include dyspnoea, easy fatigue, palpitations, exercise intolerance and recurrent respiratory infections. [symptoma.com]

Infants with large ASDs may have cyanosis, heart failure, recurrent respiratory infections, or failure to thrive. [journals.lww.com]

At the initial visit, he presented with recurrent lower respiratory infection, heart murmur, psychomotor retardation, inverted nipples, and cerebellar atrophy. [ncbi.nlm.nih.gov]

Myelodysplasia

A Japanese patient presented with lymphedema, severe Varicella zoster, and Salmonella infection, recurrent respiratory infections, panniculitis, monocytopenia, B- and NK-cell [ncbi.nlm.nih.gov]

Here we describe a 72-year-old male patient who was diagnosed with GS when he was 62, after a two-year history of recurrent respiratory infections. [ncbi.nlm.nih.gov]

Six patients had recurrent upper respiratory tract infections, unresponsive to antibiotics. [nature.com]

Mucopolysaccharidosis

The early clinical characteristics were developmental delay, joint stiffness, coarse facies, recurrent respiratory tract infections, abdominal distention and hernia. [ncbi.nlm.nih.gov]

[…] upper respiratory tract infections Obstructive lung disease Ear infections Corneal clouding and retinal degeneration Gastrointestinal problems Hirsutism Sleep problems This [giikorea.co.kr]

Wiskott-Aldrich Syndrome

respiratory infections, eczema, and thrombocytopenia. [msdmanuals.com]

Symptoms and Signs of Wiskott-Aldrich Syndrome The first manifestations are often hemorrhagic (usually bloody diarrhea), followed by recurrent respiratory infections, eczema [merckmanuals.com]

Symptoms and Signs Clinical findings of Chédiak-Higashi syndrome include oculocutaneous albinism and susceptibility to recurrent respiratory and other infections. [msdmanuals.com]

Spinal Muscular Atrophy

However, children with muscle weakness remain at risk for recurrent respiratory infection and atelectasis. [ncbi.nlm.nih.gov]

Children with this form of SMA face a difficult battle and many die from recurrent respiratory infections within the first year of life. [ucsfbenioffchildrens.org]

Recurrent respiratory infections: Tongue fasciculation and ineffective swallowing may predispose patients to frequently aspirate their food. [symptoma.com]

HIV Infection

Sores in the mouth that come and go Recurrent upper respiratory tract infections Weight loss up to 10% of the person’s usual body weight General feelings of tiredness and [health24.com]

[…] or persistent upper respiratory tract infection, sinusitis, or otitis media Splenomegaly Category B: Moderately symptomatic Children with symptomatic conditions attributed [msdmanuals.com]

[…] in the neck, armpits and groin Occasional fevers Oral candidiasis (thrush) Pulmonary tuberculosis Oral hairy leukoplakia Shingles (or Herpes zoster) Skin rashes and nail infections [health24.com]

Patent Ductus Arteriosus

Parents may note irritability, diaphoresis, difficulty feeding, poor weight gain and recurrent respiratory infections, amongst other symptoms. [youtube.com]

History:  Irritable, feed poorly, fail to gain weight and sweat excessively  Increased respiratory effort and respiratory rates  prone to develop recurrent upper respiratory [slideshare.net]

infections and pneumonia 4. [slideshare.net]