Possible Causes for refractory anemia Non-Hodgkin Lymphoma [edit] Thalassemia Sickle cell anemia Aplastic anemia Fanconi anemia Malignant infantile osteopetrosis Mucopolysaccharidosis Immune deficiency syndromes Autoimmune diseases [en.wikipedia.org] Non-Hodgkin lymphoma (NHL) (relapsed, refractory) Neuroblastoma Ewing sarcoma Multiple myeloma Myelodysplastic syndromes Gliomas, other solid tumors Non-malignant (non-cancerous [en.wikipedia.org] […] are as follows: Malignant (cancerous)[edit] Acute myeloid leukemia (AML) Chronic myeloid leukemia (CML) Acute lymphoblastic leukemia (ALL) Hodgkin lymphoma (HL) (relapsed, refractory [en.wikipedia.org] Chronic Kidney Insufficiency Abstract Anemia is a major problem in patients with chronic kidney insufficiency. The development of recombinant human erythropoietin has enabled physicians to correct this anemia. Although anemia has not been considered to be a common or important contributor to congestive heart failure, anemia of any cause can[…] [ncbi.nlm.nih.gov] Gastrointestinal Neoplasm BACKGROUND: Endoscopic submucosal dissection (ESD) is an innovative and promising procedure. However, ESD experience is mostly limited to Japan and a few countries in Asia. An appropriate training system should be proposed from Japan to promote a permeation of ESD technique. We conducted questionnaire survey to[…] [ncbi.nlm.nih.gov] Gastrointestinal Hemorrhage This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH). Main Recommendations MR1. ESGE recommends immediate assessment of hemodynamic status in patients who present[…] [ncbi.nlm.nih.gov] Bone Marrow Metastasis He had a history of myelodysplastic syndrome and refractory anemia with ringed sideroblasts diagnosed 5 years earlier. [ncbi.nlm.nih.gov] Leukoerythroblastic Anemia Pagina 61 - Refractory anemia (RA) Refractory anemia with ringed sideroblasts (RARS) Refractory anemia with excess blasts (RAEB... [books.google.it] […] pure red-cell aplasia Refractory Anemia sideroblastic anemia Thrombocytopenia, Anemia, and Myelofibrosis thrombocytosis WT Limb Blood Syndrome X-Linked Anemia with or without [rgd.mcw.edu] anemia; refractory anemia with ringed sideroblasts; chronic myelomonocytic leukemia; refractory anemia with excess blasts in transformation lab findings severe pancytopenia [memorize.com] Leukemia anemia”). [doi.org] This category includes the entities of refractory anemia (RA) for those with anemia and only dyserythropoiesis (but in whom ring sideroblasts account for less than 15% of [doi.org] anemia” and “refractory cytopenia” and replaces them with “myelodysplastic syndrome” followed by the appropriate modifiers: single vs multilineage dysplasia, ring sideroblasts [doi.org] Renal Cell Carcinoma In refractory patients, this scheme has been modified. [cancertherapyadvisor.com] In patients with prior therapy, three factors have been identified as associated with poor risk: Low performance status Anemia High corrected serum calcium Median overall [cancertherapyadvisor.com] Anemia anemia ICD-Morpho 9989/3 Myelodysplastic syndrome, unclassifiable Atlas_Id 1104 Note This disorder is part of the heterogeneous category of myelodysplastic syndrome (MDS) [atlasgeneticsoncology.org] Ferrara, Corso Giovecca 203, Ferrara, Italy (Note : for Links provided by Atlas : click ) ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS ICD-Morpho 9980/3 Refractory [atlasgeneticsoncology.org] Aplastic Anemia […] severe aplastic anemia or refractory cytopenias Embryonic/Adult Cultured Cells Related to Aplastic Anemia: Umbilical cord blood ALDH cells (ALD-151) PMIDs: 10430905 Bone [malacards.org] […] effective in improving blood counts in refractory aplastic anemia. [rarediseases.org] Aplastic Anemia. [malacards.org] Refractory Megaloblastic Anemia The etiology, clinical features and treatment of 25 cases of idiopathic refractory megaloblastic anemia are described. [bloodjournal.org] 1 refractory megaloblastic anemia Медицина: мегалобластная рефрактерная анемия Универсальный англо-русский словарь 2 refractory megaloblastic anemia мегалобластная рефрактерная [translate.academic.ru] * Orotic aciduria -- refractory megaloblastic anemia #437956 why megaloblastic anemia is associated with orotic aciduria ? kindly explain to me please thank you. [usmleforum.com] Acute Myeloid Leukemia Cytogenetic investigation of the bone marrow cells of an 88-year-old woman with refractory anemia with an excess of blasts in transformation with progression to acute myelocytic [ncbi.nlm.nih.gov] This category includes the entities of refractory anemia (RA) for those with anemia and only dyserythropoiesis (but in whom ring sideroblasts account for less than 15% of [doi.org] Blood Disorders : Patients with myelodysplasia (or refractory anemia), polycythemia vera, or essential thrombocythemia have a higher risk of developing AML. [knowcancer.com] Multiple Myeloma The patient in our case study suffered refractory anemia following surgery and 2 cycles of chemotherapy. [ncbi.nlm.nih.gov] Therefore, when CRC is associated with refractory anemia, we should not only assume that anemia is a classical symptom of CRC, a result of chronic blood loss, nutritional [ncbi.nlm.nih.gov] These new symptoms drew our attention, and we considered a diagnosis of synchronous primary CRC and MM, with the anemia as a symptom of MM. [ncbi.nlm.nih.gov] Paroxysmal Nocturnal Hemoglobinuria The presence of a subclinical PNH population in myelodysplastic bone marrow disorders, such as aplastic anemia or refractory anemia, may correlate with a positive immunotherapeutic [ltd.aruplab.com] How to diagnose PNH Patients with a Coombs-negative hemolytic anemia, AA, refractory anemia, and unexplained thrombosis in conjunction with cytopenias or hemolysis should [bloodjournal.hematologylibrary.org] MDS patients reported to possess PNH cells tend to be classified as refractory anemia and often have the following characteristics: a hypocellular marrow, human leukocyte [bloodjournal.hematologylibrary.org] Idiopathic Refractory Anemia Aplastic anemia (AA) needs to be differentiated from hypoplastic MDS particularly primary hypoplastic refractory anemia (PHRA) because of the impact on management and prognosis [ncbi.nlm.nih.gov] Kushner JP, Lee GR, Wintrobe MM, Cartwright GE (1971) Idiopathic refractory sideroblastic anemia. [link.springer.com] MDS indicates myelodysplastic syndrome; RA, refractory anemia ; RARS, refractory anemia with ringed sideroblasts; RAEB, refractory anemia with excess of blasts; RAEB-T, RAEB [medical-dictionary.thefreedictionary.com] Menorrhagia Preoperative magnetic resonance imaging accurately diagnosed adenomyosis uteri in three women. We performed laparoscopic excision of myometrial adenomyomas and localized portions of adenomyosis uteri in all women in whom the disorder was accompanied by severe dysmenorrhea and hypermenorrhea. We used the same[…] [ncbi.nlm.nih.gov] Chronic Lymphocytic Leukemia Five patients had refractory cytopenia with multilineage dysplasia, and 3 patients had refractory anemia with excess blasts-2 (RAEB-2). [dx.doi.org] Refractory: CLL does not respond to standard treatments. [rarediseases.org] Approximately 5-10% of CLL is complicated by autoimmune cytopenia (AIC), such as autoimmune hemolytic anemia (AIHA). [ncbi.nlm.nih.gov] Primary Myelofibrosis […] frequency of leukemic blast cells (its degree of leukemicness) and, therefore, its course, than to clonal sideroblastic anemia (‘refractory sideroblastic anemia in the WHO [doi.org] anemia with excess of blasts (RAEB) or refractory anemia with excess of blasts in transformation (RAEB-t) with an IPSS score of 1.5 (appendix C) Note: Subjects with a secondary [vademecumhematologie.nl] anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-t) Myelodysplastic syndrome (MDS) Diagnosis of MPN For diagnosis of MPN the criteria include: [news-medical.net] Refractory Anemia with Excess Blasts in Transformation We next assessed hematologic and clinical relevance between refractory anemia with excess blasts (RAEB) and RAEBt patients with PB blasts of or 5%. [ncbi.nlm.nih.gov] (Also known as/Synonyms) RAEB (Refractory Anemia with Excess Blasts) What is Refractory Anemia with Excess Blasts? [dovemed.com] There are no specific chromosomal abnormalities associated with refractory anemia with excess blasts in transformation [RAEB-T]. [ncbi.nlm.nih.gov] Iron Deficiency Anemia […] genetics* Anemia, Refractory/diagnosis Anemia, Refractory/drug therapy* Anemia, Refractory/genetics* Child Child, Preschool Chromosome Aberrations* DNA Mutational Analysis [ncbi.nlm.nih.gov] KEYWORDS: TMPRSS6; hepcidin; iron refractory iron deficiency anemia [ncbi.nlm.nih.gov] refractory anemia after all standard diagnostic requirements have already been fulfilled. [bloodjournal.org] Sideroblastic Anemia The chromosomal pattern of the patient was varied, and was accompanied by the development of refractory anemia with an excess of blasts from refractory anemia with ringed [ncbi.nlm.nih.gov] Gov't MeSH terms 5-Aminolevulinate Synthetase/deficiency 5-Aminolevulinate Synthetase/genetics Anemia, Refractory/blood Anemia, Refractory, with Excess of Blasts/blood Anemia [ncbi.nlm.nih.gov] We report two unrelated cases of highly pyridoxine-responsive XLSA in geriatric patients previously diagnosed with refractory anemia and ringed sideroblasts. [ncbi.nlm.nih.gov] Philadelphia Chromosome Positive Chronic Myeloid Leukemia Le Beau et al. found that the FMS and GM-CSF genes were both deleted from the chromosome 5q- in BM cells in two patients with refractory anemia and del(5)(q15-q33.3) [ 8 ] [omicsonline.org] anemia with excess of blasts with basophilia, AML with eosinophilia, and acute eosinophilic leukemia, ACSL6 was identified as a fusion partner to ETV6 (OMIM: 600618) in recurrent [omicsonline.org] […] and IRF1 (OMIM: 147575) genes at 5q31.1, CSF1R (OMIM: 164770) and PDGFRB (OMIM: 17341) genes at 5q32, and the RPS14 (OMIM: 130620) gene at 5q33.1.6 In single patients with refractory [omicsonline.org] Hodgkin Lymphoma [edit] Thalassemia Sickle cell anemia Aplastic anemia Fanconi anemia Malignant infantile osteopetrosis Mucopolysaccharidosis Pyruvate kinase deficiency Immune deficiency [en.wikipedia.org] Non-Hodgkin lymphoma (NHL) (relapsed, refractory) Neuroblastoma Ewing sarcoma Multiple myeloma Myelodysplastic syndromes Gliomas, other solid tumors Non-malignant (non-cancerous [en.wikipedia.org] […] are as follows: Malignant (cancerous)[edit] Acute myeloid leukemia (AML) Chronic myeloid leukemia (CML) Acute lymphoblastic leukemia (ALL) Hodgkin lymphoma (HL) (relapsed, refractory [en.wikipedia.org] Chronic Myeloid Leukemia anemia with excess blasts in transformation [RAEB T] Type 1 Excludes acute exacerbation of chronic myeloid leukemia ( C92.10 ) refractory anemia with excess of blasts not [icd10data.com] anemia”). [doi.org] anemia (RA), refractory anemia with ringed sideroblasts (RARS), and refractory anemia with excess blasts (RAEB). 18 Poor-risk cytogenetic abnormalities, including abnormalities [doi.org] Myelodysplasia anemia (RA) 1 10-20 30-65 10-40 Refractory anemia with ringed sideroblasts (RARS) 1 10-35 34-83 10-35 Refractory anemia with excess blasts (RAEB) 5-20 50 8-18 25-30 Refractory [web.archive.org] Reportable disorder s include: MDS, refractory anemia, refractory anemia with excess blasts in transformation, refractory anemia with ring sideroblast s, refractory anemia [seer.cancer.gov] Refractory anemia with ring sideroblasts (RARS) is a subtype of myelodysplastic syndrome (MDS) characterized by 15% or more ring sideroblasts in the bone marrow according [ncbi.nlm.nih.gov] Refractory Anemia Reciprocal translocation is relatively uncommon in refractory anemia. [ncbi.nlm.nih.gov] Refractory anemia with ring sideroblasts (RARS) is a subtype of myelodysplastic syndrome (MDS) characterized by 15% or more ring sideroblasts in the bone marrow according [ncbi.nlm.nih.gov] Prevention - Refractory anemia Not supplied. Diagnosis - Refractory anemia Not supplied. [checkorphan.org] Sickle Cell Anemia Because some of the refractory sickle cell anemia patients require stem cell bone marrow transplant, the effects on fertility must be discussed with this treatment as well [oncofertility.northwestern.edu] Two of the patients had sickle cell anemia [Hb S (HBB: c.20A T) (β(S)/β(S))] with refractory leg ulcers that required amputations. [ncbi.nlm.nih.gov] […] fertility planning and consultation before administration of hydroxyurea in the event that a malignancy occurs as a side effect of this preventative treatment for sickle cell anemia [oncofertility.northwestern.edu] Acute Erythroblastic Leukemia Refractory anemias: acquired enzymopathies of hematopoietic stem cells. Nouv Rev Fr Hematol 1969; 9 :65–86. 8. Kiossoglou KA, Mitus WJ, Dameshek W. [doi.org] anemia with excess blasts and preceding or concurrent history of erythropoietin therapy for anemia (n 16). [ncbi.nlm.nih.gov] anemia with increase in blasts, chronic myelomonocytic leukemia, and preleukemia). [web.archive.org] Acute Monocytic Leukemia Two had acute monocytic leukemia (AMoL), one had chronic myelomonocytic leukemia, one had refractory anemia, and the other had juvenile chronic myelogenous leukemia. [ncbi.nlm.nih.gov] Anemia Completed NCT00046930 Phase 3 cytarabine;daunorubicin hydrochloride;zosuquidar trihydrochloride;Placebo 19 Cyproheptadine in Preventing Weight Loss in Children Receiving [malacards.org] (PRCA)赤芽球ろう purpura紫斑 r refractory anemia with excess of blasts (RAEB)移行型芽球増加型不応性貧血 remission induction寛解導入 retrovirus レトロウイルス rouleaux formation連銭形成 s severe combined immunodeficiency [tokyo-med.ac.jp] Pancytopenia Bone marrow aspiration revealed refractory anemia with ringed sideroblasts of myelodysplastic syndrome (MDS). [jstage.jst.go.jp] […] and some refractory anemia patients. [cancertherapyadvisor.com] Peripheral blood flow cytometry to look for PNH should be performed on all patients with aplastic anemia, suspected PNH, and certain forms of MDS, including hypoplastic MDS [cancertherapyadvisor.com]
