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867 Possible Causes for Refractory Seizures

  • Febrile Infection-Related Epilepsy Syndrome

    Febrile infection-related epilepsy syndrome (FIRES) is a severe epileptic syndrome that manifests with refractory seizures or status epilepticus in previously healthy children[ncbi.nlm.nih.gov] IVIG was administered as an immunomodulator for refractory seizures on day-9. The patient was extubated on day 11.[ncbi.nlm.nih.gov] Diagnostic methods FIRES should be suspected when the acute onset of refractory seizures follows a few days after a simple febrile illness in previously healthy children.[orpha.net]

  • Status Epilepticus

    Herpes simplex virus (HSV) is a common cause of viral encephalitis that can lead to refractory seizures.[ncbi.nlm.nih.gov] A 17-year-old girl presented as acute psychosis, refractory seizures, hyperkinesia, autonomic instability, and soon progressed to a dissociative state of coma.[ncbi.nlm.nih.gov] We report a case of a 60-year-old man with HSV encephalitis, who presented with seizures originating from the right temporal lobe refractory to maximal medical management.[ncbi.nlm.nih.gov]

  • New-Onset Refractory Status Epilepticus

    In this case, NORSE was the presenting feature of HSE and the refractoriness of her seizures was terminated only after treating the exact cause, that is, encephalitis.[ncbi.nlm.nih.gov] Acute encephalitis with refractory, repetitive partial seizures: case reports of this unusual post-encephalitic epilepsy.[journal.frontiersin.org] An immunologic case study of acute encephalitis with refractory, repetitive partial seizures.[rarediseases.org]

  • Neonatal Seizures

    Because of its efficacy for both seizures and neuroprotection, topiramate could be a useful choice in refractory neonatal seizures.[ncbi.nlm.nih.gov] […] of refractory neonatal seizures. 16 After isolating potentially treatable metabolic and infectious causes, we should concentrate on refractory seizures due to asphyxia, where[dovepress.com] This report describes the initiation of levetiracetam in 3 infants, aged 2 days to 3 months, for refractory seizures or intolerance to other anticonvulsants.[ncbi.nlm.nih.gov]

  • Hypothalamic Hamartoma

    A young female patient with a small HH and refractory seizures is reported here.[ncbi.nlm.nih.gov] Patients typically develop cognitive deterioration and refractory seizures.[ncbi.nlm.nih.gov] The Gamma-knife technique is a safe and effective option for the treatment of hypothalamic hamartomas that produce epileptic seizures refractory to medical treatment and/or[ncbi.nlm.nih.gov]

  • Alpers Syndrome

    seizures, neurodegeneration, and liver disease.[ncbi.nlm.nih.gov] Two missense variants, c.248T C (p.L83P), c.2662G A (p.G888S) in POLG1 were detected in a 10-year-old Chinese girl with refractory seizures, acute liver failure after exposure[ncbi.nlm.nih.gov] Alpers syndrome affects children and young adults and is characterized by the clinical triad of refractory seizures, psychomotor regression, and characteristic liver disease[kegg.jp]

  • Temporal Lobe Epilepsy

    The authors present the case of a 51-year-old woman with a 4-year history of medication-refractory seizures, which were localized on electroencephalography to the right temporal[ncbi.nlm.nih.gov] The deficit can worsen following surgery to relieve refractory seizures.[ncbi.nlm.nih.gov] We recently encountered a 53-year-old female with refractory seizures and a semiology strongly suggesting mesial temporal lobe epilepsy.[ncbi.nlm.nih.gov]

  • Epilepsy

    CASE PRESENT: We presented a case with refractory myoclonic seizures, and progressive neurological deterioration, diagnosed as PME and neuronal ceroid lipofuscinosis disease[ncbi.nlm.nih.gov] Focal seizures began at 5 years and were refractory to medical treatment.[ncbi.nlm.nih.gov] seizures.[ncbi.nlm.nih.gov]

  • Autoimmune Encephalopathy

    All patients developed refractory seizures, and five had status epilepticus. Five of the six patients had at least one CSF abnormality.[mdedge.com] ), contactin- associated protein-like 2 [Caspr2] (LE with neuromyotonia or Morvan's syndrome), GABAaR (refractory seizures), metabotropic glutamate receptor 5 [mGluR5] (LE[neurologyindia.com] ANTI-GABAA ENCEPHALITIS • Rapidly progressive, severe encephalopathy that result in refractory seizures (Petit-Pedrol et al., 2014) • Extensive MRI abnormalities on FLAIR[slideshare.net]

  • Hyperventilation

    Abstract Topiramate is a recently released antiepileptic agent used in the treatment of patients with refractory seizure disorders.[ncbi.nlm.nih.gov] A 52-year-old woman with refractory seizure disorder was admitted to the burn care unit with burns over 10% of her body.[ncbi.nlm.nih.gov]

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