Renal-abnormalities: Causes & Reasons

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Possible Causes for renal abnormalities

Bilateral Renal Dysplasia

There is a male predominance (ratio M2.4/F1) but females are twice as likely to have bilateral multicystic dysplastic kidney disease and associated non-renal abnormalities [cags.org.ae]

No karyotype abnormalities were found in fetuses with unilateral MCDK if an associated non-renal abnormality was not found. [fetalsono.com]

Key Points Multicystic dysplastic kidney (MCDK) is a severe renal abnormality associated with atretic ureter and absence of normal renal parenchyma, which is replaced by multiple [mhmedical.com]

Renal Cysts and Diabetes Syndrome

Impaired glucose tolerance Genitourinary Abnormal nephrogenesis Abnormal renal calyces Abnormal renal pelves Asthenospermia Atresia of the vas deferens Bicornuate uterus [datagenno.com]

renal pelvices, abnormal calyces, small kidney, single kidney, horseshoe kidney, and hyperuricaemic nephropathy. [medical-dictionary.thefreedictionary.com]

In a pooled analysis, antenatal renal abnormalities, renal hyperechogenicity and cysts were discriminatory in children, whereas renal hypoplasia and cysts were discriminatory [karger.com]

Bilateral Multicystic Dysplastic Kidney

No karyotype abnormalities were found in fetuses with unilateral MCDK if an associated non-renal abnormality was not found. [fetalsono.com]

It is an abnormality of the embryonic development in which the renal parenchyma is substituted by nonfunctioning renal tissue made up of cysts which do not communicate with [sjkdt.org]

Unilateral Renal Agenesis

We determined the incidence of associated renal abnormalities in children with unilateral renal agenesis. [ncbi.nlm.nih.gov]

RESULTS: The prevalence of auditory abnormalities in children with unilateral renal agenesis (4/75) (5.3%) was higher than in the control group (0%). [ncbi.nlm.nih.gov]

Although mice lacking functional ret may have renal agenesis or dysgenesis, no clinically relevant renal abnormalities have been reported in patients with familial medullary [nejm.org]

Fraser Syndrome

Fetopathological examination revealed that the oligoamnios sequence was due to major renal abnormalities (bilateral renal agenesis in the first, and unilateral renal agenesis [ncbi.nlm.nih.gov]

All of the cases had ocular, otic, digital, laryngeal, and renal abnormalities. Details of the pregnancies and sibship data are also reported. [ncbi.nlm.nih.gov]

The prenatal ultrasound can reveal features like polyhydramnios or oligohydramnios, echogenic lungs, renal abnormalities or agenesis and cryptophthalmos that are pathognomonic [ncbi.nlm.nih.gov]

Laurence Moon Syndrome

Key words Bardet-Biedl syndrome Laurence-Moon-Biedl syndrome Renal abnormalities Renal imaging This is a preview of subscription content, log in to check access. [link.springer.com]

We conclude that Laurence–Moon–Biedl syndrome includes the presence of renal abnormalities. (N Engl J Med 1988;319:615–8.) [nejm.org]

Renal abnormalities While the secondary features are stated to be as: 1. Speech disorder and/or developmental delay 2. [en.wikipedia.org]

Urinary Tract Infection

Recurrent chronic lower abdominal pain and urinary tract infection in a young person may be due to congenital renal abnormality. [ncbi.nlm.nih.gov]

Abnormalities of renal tract function and/or structure. [dx.doi.org]

Abnormality of the renal tract Incomplete bladder emptying - particularly by prostatic obstruction in men. [patient.info]

Alagille Syndrome

[…] frequent renal abnormalities. [ncbi.nlm.nih.gov]

Various renal abnormalities have also been associated with Alagille syndrome, whereas renal vascular hypertension combined with renal insufficiency has been reported in several [ncbi.nlm.nih.gov]

Alagille syndrome is a rare developmental disorder combining bile duct paucity, congenital cardiopathy, facial dysmorphy, vertebrae defects, and ocular abnormalities, and [ncbi.nlm.nih.gov]

Renal Coloboma Syndrome

Renal-coloboma syndrome is a recently described autosomal dominant syndrome of abnormal optic nerve and renal development. [ncbi.nlm.nih.gov]

BACKGROUND: Renal-coloboma syndrome (RCS) is an autosomal dominant disorder characterized by renal abnormalities and optic nerve defects, caused by heterozygous mutations [ncbi.nlm.nih.gov]

Renal coloboma syndrome is a rare autosomal dominant disorder characterized by renal hypodysplasia and optic nerve abnormalities, caused by heterozygous mutations in the PAX2 [journals.lww.com]

Vesicoureteral Reflux

[…] with renal function abnormalities had moderate to severe abnormalities. [pediatrics.aappublications.org]

[…] of existing renal cortical abnormalities that may affect decision-making. [auanet.org]

; urethral meatal stenosis Functional: bladder and bowel dysfunction ; neurogenic bladder Cystitis Congenital anomalies of the ureter Ureteral duplication (most common renal [amboss.com]

Acute Gastroenteritis

The first episode of urinary retention lasted for 24 hours; radiological evaluation (Magnetic Resonance, cistography and renal ultrasound) did not find abnormality; it was [ncbi.nlm.nih.gov]

Acute Cystitis

Abnormalities of renal tract function and/or structure. [dx.doi.org]

Abnormality of the renal tract Incomplete bladder emptying - particularly by prostatic obstruction in men. [patient.info]

The study by Pettersson 1989 included patients with upper renal tract abnormalities, while Lee 2007 also included patients with renal tract abnormalities (15 patients had [dx.doi.org]

Acute Bronchitis

A range of other significant abnormalities was found, including hydronephrosis, VUR and calculi. [onlinelibrary.wiley.com]

Incidental renal or ureteric stones may be detected with relatively high frequency in some parts of the world [63]. [onlinelibrary.wiley.com]

Acute Alcohol Intoxication

Abstract Traumatic and nontraumatic rhabdomyolysis can lead to acute renal failure (ARF), and acute alcohol intoxication can lead to multiple abnormalities of the renal tubules [ncbi.nlm.nih.gov]

In addition to metabolic acidosis, acute renal failure and neurologic disease can occur in some of the intoxications. [cjasn.asnjournals.org]

[…] dysfunction, and finally renal dysfunction ( 13, 37, 57 ). [cjasn.asnjournals.org]

Vitamin D Deficiency

Fourth, as already noted, low 25(OH)D levels may be associated with secondary HPT and abnormal bone mineralization. [ncbi.nlm.nih.gov]

When assessing urine calcium values, it is important to note that thiazide diuretics, lithium, and a low-sodium diet decrease renal calcium excretion, whereas excess sodium [ncbi.nlm.nih.gov]

Sickle Cell Nephropathy

(41) Hematuria7(8.5) Hemoglobinuria12 (14,5) BUN Blood urea nitrogen, S Serum 10 Renal abnormalities in SCD Various forms of renal abnormalities have been observed in SCD [slideplayer.com]

Renal abnormalities are common complications of sickle cell disease (SCD). [ncbi.nlm.nih.gov]

In some cases, it may result from papillary necrosis 15 Summary renal abnormalities, particularly proteinuria, are common in adolescent and adult patients with SCD. [slideplayer.com]

Renal Tubular Dysfunction

However, a variety of renal tubular abnormalities including hypercalciuria, hypo-magnesemia with renal magnesium wasting, decreased tubular absorption of phosphorus, hypo-uricemia [ncbi.nlm.nih.gov]

The aim of this study is to investigate the occurrence of renal tubular abnormalities among patients with SCD. [karger.com]

The abnormalities of blood chemistry and renal tubular function disappeared after four weeks of abstinence. [ncbi.nlm.nih.gov]

Bardet-Biedl Syndrome Type 11

Abnormal renal development was confirmed in almost 50% of the patients ( Table 2 ). [cjasn.asnjournals.org]

Prognosis The renal abnormalities are the main life-threatening manifestations because they can lead to end-stage renal failure and require renal transplantation. [orpha.net]

The main features are obesity, polydactyly, pigmentary retinopathy, learning disabilities, various degrees of intellectual impairment, hypogonadism, and renal abnormalities [scielo.br]

Horseshoe Kidney

Primary renal neuroendocrine tumors (NETs) are low-grade tumors with neuroendocrine differentiation and have been reported to arise most commonly in renal abnormalities such [ncbi.nlm.nih.gov]

Horseshoe kidney is a fairly common renal abnormality that results in two normal, functioning kidneys that are connected at the lower poles by a fibrous tissue. [fhmedicalgroup.com]

Since prenatal ultrasound is now a part of the routine care during pregnancy, many renal abnormalities are discovered before the baby is even born. [chop.edu]

Renal Agenesis

Renal Dysgenesis: Abnormal kidney development, which includes aplasia, hypoplasia, dysplasia, and cystic disease. [sjkdt.org]

Abdominal ultrasound of neonate helps confirm renal abnormalities noted prenatally. Chest X-ray of neonate reveals spontaneous pneumothorax and pulmonary hypoplasia. [quizlet.com]

Bilateral renal agenesis is a rare abnormality of renal development occuring in one to three per 10,000 births. [fetalsono.com]

Cystitis

Some underlying conditions include diabetes, symptoms for 7 days or longer before seeking care, renal failure, functional or anatomic abnormality of the urinary tract, renal [emedicine.medscape.com]

[…] insufficiency, functional or anatomic abnormality in the urinary tract, and obstructive uropathy. [ncbi.nlm.nih.gov]

[…] ultrasound, CT scan, or MRI ) can be performed to rule out an abscess or other abnormalities. [medicinenet.com]

Vitamin B12 Deficiency

and vitamin B6 deficiency can impact homocysteine levels.10,11 For these reasons, it has been recommended that abnormal results of two or more tests be used to confirm a [todaysdietitian.com]

Holo-TCII levels may dip temporarily due to drug interactions or be affected by pregnancy, oral contraceptives, folate disorders, and alcoholism, plus folate, renal dysfunction [todaysdietitian.com]

Acrorenal Mandibular Syndrome

The features are compared with other cases with limb and renal abnormalities reported in the literature. [insights.ovid.com]

Abstract Author Information Authors Article Metrics Metrics A fetus with ectrodactyly, Pierre Robin sequence, renal aplasia and other anomalies is reported. [journals.lww.com]

This case along with similar two cases reported by Halal and Tobias delineates acro-renal-mandibular syndrome as a distinct entity. [insights.ovid.com]

Proximal Renal Tubular Acidosis

Abstract Mutations in the Na -HCO3- co-transporter (NBC1) cause permanent proximal renal tubular acidosis (pRTA) with ocular abnormalities. [ncbi.nlm.nih.gov]

Abstract Proximal renal tubular acidosis associated with ocular abnormalities such as band keratopathy, glaucoma, and cataracts is caused by mutations in the Na( )-HCO(3) [ncbi.nlm.nih.gov]

Abstract Proximal renal tubular acidosis associated with ocular abnormalities such as band keratopathy, glaucoma, and cataracts is caused by mutations in the Na -HCO3– cotransporter [jci.org]

Hypertension

The aetiology of hypertension in Turner syndrome varies, even in the absence of cardiac anomalies and obvious structural renal abnormalities. [ncbi.nlm.nih.gov]

[…] tumor Neuroblastoma Coarctation of the aorta Renal parenchymal disease Renovascular abnormalities Endocrine causes Essential hypertension Essential hypertension Renal parenchymal [web.archive.org]

[…] biopsy did not reveal any abnormalities. [ncbi.nlm.nih.gov]

Chronic Kidney Insufficiency

abnormalities Renal biopsy results and any surgical notes Neurological exam results, if you experience nephropathy Other diagnostic test results documenting any complications [disability-benefits-help.org]

renal histological abnormalities, structural abnormalities detected by imaging (e.g. polycystic kidneys, reflux nephropathy) or a history of kidney transplantation. [renal.org]

[…] disease: A formal diagnosis and physical exam notes Repeated and recent urinalysis results, documenting serum creatinine and albumen Imaging scans, if you have kidney or renal [disability-benefits-help.org]

Post-Infectious Glomerulonephritis

[…] overweight/obese status prolonged time to resolution of renal abnormalities after PIGN. [ncbi.nlm.nih.gov]

PSGN is a self-limited disease, especially in children, but long-term follow-up studies indicate persistent low-grade renal abnormalities in a significant proportion of patients [ncbi.nlm.nih.gov]

Schedl A (2007) Renal abnormalities and their developmental origin.Nat Rev Genet 8: 791-802. [omicsonline.org]

Renal Artery Stenosis

We present a unique multimodality case of abnormal radiotracer uptake in the renal parenchyma on 123-Iodine metaiodobenzylguanidine (123I MIBG) scan in a patient with unilateral [ncbi.nlm.nih.gov]

However, 8 of 11 patients studied had abnormal renal morphology or function. [pediatrics.aappublications.org]

abnormalities Unexplained renal failure in patients aged 50 years Elevation in plasma creatinine level after the initiation of ACE-I or AII-RB therapy Asymmetrical kidneys [bmb.oxfordjournals.org]

Renal Malrotation

Its association with renal ectopia suggests that the process of ascent and rotation are related. abnormal renal rotation may cause partial ureteropelvic junction (UPJ) obstruction [radiopaedia.org]

Renal abnormalities and their developmental origin. Nat Rev Genet. 2007 Oct;8(10):791-802. PMID: 17878895 Rodriguez MM. [humpath.com]

[…] anal, cardiac, tracheal, esophageal, renal, limb) syndrome. [4, 5, 6] Anomalies of the kidneys can occur in VATER association; the most common of these renal abnormalities [emedicine.medscape.com]

Anemia

[…] may facilitate early diagnosis (e.g., café-au-lait spots; microsomy; low birth weight; thumb, renal, skeletal, and eye abnormalities) Microcytic anemia and reticulocytopenia [aafp.org]

Microangiopathic hemolytic anemia, thrombocytopenia, normal coagulation test results, and renal and neurologic abnormalities should lead the physician to the diagnosis. [emedicine.com]

and pancreatic insufficiency or failure; and congenital dyserythropoietic anemia, in which chronic anemia (typically macrocytic) results from ineffective or abnormal RBC [merckmanuals.com]