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26 Possible Causes for Renal Corticomedullary Differentiation Reduced

  • Nephronophthisis-Like Nephropathy

    Ultrasound findings are increased echogenicity, reduced corticomedullary differentiation, and renal cysts (in 50% of affected individuals).[ncbi.nlm.nih.gov] At the preazotemic stage, the kidneys maintain a normal or slightly reduced size and on renal ultrasound, they present increased medullary echogenicity with diminished corticomedullary[sjkdt.org] Histologic findings include tubulointerstitial fibrosis, thickened and disrupted tubular basement membrane, sporadic corticomedullary cysts, and normal or reduced kidney size[ncbi.nlm.nih.gov]

  • Renal Vein Thrombosis

    […] loss of corticomedullary differentiation, reduced echogenicity around pyramids and echogenic band at the extreme apex of the pyramid.[ncbi.nlm.nih.gov] […] medullary pyramids, subsequently loss of corticomedullary differentiation, reduced echogenicity around the affected pyramids and echogenic band at the extreme apex of the[ncbi.nlm.nih.gov] Initial ultrasound diagnostic features include: renal enlargement, echogenic medullary streaks, lack of the flow pattern characteristic of arcuate vessels and subsequently[ncbi.nlm.nih.gov]

  • Cornelia De Lange Syndrome

    renal corticomedullary differentiation 0005565 Self-injurious behavior Self-injurious behaviour 0100716 Short sternum 0000879 Single transverse palmar crease 0000954 Sporadic[rarediseases.info.nih.gov] Middle ear infection 0000388 Phocomelia 0009829 Pneumonia 0002090 Proptosis Bulging eye Eyeballs bulging out Prominent eyes Prominent globes Protruding eyes [ more ] 0000520 Reduced[rarediseases.info.nih.gov]

  • Nephronophthisis 16

    Ultrasound findings are increased echogenicity, reduced corticomedullary differentiation, and renal cysts (in 50% of affected individuals).[ncbi.nlm.nih.gov] At the preazotemic stage, the kidneys maintain a normal or slightly reduced size and on renal ultrasound, they present increased medullary echogenicity with diminished corticomedullary[sjkdt.org] Histologic findings include tubulointerstitial fibrosis, thickened and disrupted tubular basement membrane, sporadic corticomedullary cysts, and normal or reduced kidney size[ncbi.nlm.nih.gov]

  • Cystic Kidney

    Fig. 9 Juvenile nephronophthisis – sonographic appearance: normal or reduced kidney size, enhanced echogenicity of the renal cortex, and reduced corticomedullary differentiation[link.springer.com] In pre- and postnatal ultrasound, the kidneys appear grossly enlarged, with increased echogenicity and reduced corticomedullary differentiation [ 25 , 26 ] (Fig. 5 a–d).[link.springer.com] The clinical spectrum of ARPKD ranges from intrauterine death to early renal failure and hypertension or preserved renal function into adulthood [ 24 ].[link.springer.com]

  • Allan-Herndon-Dudley Syndrome

    renal corticomedullary differentiation Prominent forehead Hydroureter Thyroid agenesis Breathing dysregulation Strabismus Gastroesophageal reflux Small for gestational age[mendelian.co] Tubulointerstitial fibrosis Hypokalemic alkalosis Hypokalemic metabolic alkalosis Mesangial hypercellularity Red urine Hypochloremic metabolic alkalosis Global glomerulosclerosis Reduced[mendelian.co]

  • Ichthyosis - Oral and Digital Anomalies Syndrome

    renal corticomedullary differentiation Intellectual disability, severe Hypertonia Agenesis of corpus callosum Posteriorly rotated ears Absent speech Low-set, posteriorly[mendelian.co] Hepatomegaly Upslanted palpebral fissure Oxycephaly Polydactyly Craniosynostosis Micromelia Recurrent respiratory infections Short stature Global glomerulosclerosis Hirsutism Reduced[mendelian.co]

  • Nephronophthisis 7

    Additional findings include small-to-normal-sized hyperechogenic kidneys with reduced corticomedullary differentiation on abdominal ultrasonography and histopathological alterations[dnatesting.uchicago.edu] At the preazotemic stage, the kidneys maintain a normal or slightly reduced size and on renal ultrasound, they present increased medullary echogenicity with diminished corticomedullary[sjkdt.org] […] characterized by thickened or disrupted tubular basement membranes, tubular atrophy and dilation, interstitial fibrosis and occasional renal cysts.[dnatesting.uchicago.edu]

  • Nephronophthisis

    Additional findings include small-to-normal-sized hyperechogenic kidneys with reduced corticomedullary differentiation on abdominal ultrasonography and histopathological alterations[dnatesting.uchicago.edu] At the preazotemic stage, the kidneys maintain a normal or slightly reduced size and on renal ultrasound, they present increased medullary echogenicity with diminished corticomedullary[sjkdt.org] […] characterized by thickened or disrupted tubular basement membranes, tubular atrophy and dilation, interstitial fibrosis and occasional renal cysts.[dnatesting.uchicago.edu]

  • Nephronophthisis

    Additional findings include small-to-normal-sized hyperechogenic kidneys with reduced corticomedullary differentiation on abdominal ultrasonography and histopathological alterations[dnatesting.uchicago.edu] At the preazotemic stage, the kidneys maintain a normal or slightly reduced size and on renal ultrasound, they present increased medullary echogenicity with diminished corticomedullary[sjkdt.org] […] characterized by thickened or disrupted tubular basement membranes, tubular atrophy and dilation, interstitial fibrosis and occasional renal cysts.[dnatesting.uchicago.edu]

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