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173 Possible Causes for Renal Phosphate Wasting

  • Pegvisomant

    phosphate wasting associated with rickets/osteomalacia ( 1 – 3 ).[academic.oup.com] phosphate wasting; ST, Sertoli cell tumor of the testes; NR, normal range. a Substitution of the amino acid cysteine (Cys) or histidine (His) for arginine at position 201[academic.oup.com] , café-au-lait skin pigmentation, and hyperfunctioning endocrinopathies, such as precocious puberty (PP), GH excess (acromegaly), hyperthyroidism, hypercortisolism, and renal[academic.oup.com]

  • Autosomal Recessive Mental Retardation 46

    wasting.[iofbonehealth.org] (OMIM phenotype number #241520 ) Autosomal recessive hypophosphatemic rickets (ARHR) is an extremely rare disease, characterized by hypophosphatemia resulting from renal phosphate[iofbonehealth.org]

  • Fibrous Dysplasia

    In univariate analysis, younger age at diagnosis, renal phosphate wasting, a polyostotic form, prevalent fracture, and bisphosphonate use were significant predictors.[ncbi.nlm.nih.gov] "FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting" .[en.wikipedia.org]

  • Saethre-Chotzen Syndrome

    Additionally, the patient had some unusual findings as part of generalized dysfunction of the renal tubules including hypophosphatemia with renal phosphate wasting, normocalcemic[ncbi.nlm.nih.gov] […] hypercalciuria, hypomagnesemia with renal magnesium wasting, low-molecular-weight proteinuria, decreased serum PTH levels, osteopenia, and nephrolithiasis.[ncbi.nlm.nih.gov]

  • Hypophosphatemia

    We present 2 infants with end-stage liver disease due to biliary atresia (BA) who developed hypophosphatemia with renal phosphate wasting.[ncbi.nlm.nih.gov] Tumor-induced osteomalacia is a rare acquired metabolic bone disorder characterized by isolated renal phosphate wasting due to abnormal tumor production of fibroblast growth[ncbi.nlm.nih.gov] Pathologically elevated serum levels of fibroblast growth factor-23 (FGF23), a bone-derived hormone that regulates phosphorus homeostasis, result in renal phosphate wasting[ncbi.nlm.nih.gov]

  • Vitamin D Deficiency

    wasting of phosphate that occurs as a result of a mutation in the PHEX gene.[ncbi.nlm.nih.gov] […] patient described here presented for evaluation of bowing of his lower extremities, and was ultimately diagnosed with X-linked hypophosphatemic rickets, a disorder caused by renal[ncbi.nlm.nih.gov]

  • Gitelman Syndrome

    Since the bulk of filtered phosphate is reabsorbed in the proximal tubule, renal phosphate wasting is considered exceptional in Gitelman syndrome.[ncbi.nlm.nih.gov] Because vitamin D deficiency leads to secondary hyperparathyroidism, which affects renal tubule phosphate transport, causes renal phosphate wasting and hypophosphatemia. [[sjkdt.org] The results of our case-control study disclose a hitherto unrecognized tendency towards renal phosphate wasting with mild to moderate hypophosphatemia in Gitelman syndrome[ncbi.nlm.nih.gov]

  • Jarcho-Levin Syndrome

    Ward LM et al. (2005) Renal phosphate--wasting disorders in childhood. [ ] 15. van der Linden-van der Zwaag H et al. (2006) Massive osteolysis (Gorham's disease) affecting[moldiag.de]

  • Hypophosphatemic Rickets

    Oral phosphorus and calcitriol improved metaphyseal mineralization, yet serum phosphate levels remained relatively low and renal phosphate wasting persisted.[ncbi.nlm.nih.gov] This previously undescribed PHEX mutation is probably the cause of renal phosphate wasting in our patient that resulted in rickets.[ncbi.nlm.nih.gov] X-linked hypophosphatemia (XLH) is characterized by renal phosphate wasting with hypophosphatemia, short stature, and rachitic manifestations.[ncbi.nlm.nih.gov]

  • Phosphate Decreased

    The syndrome of oncogenic osteomalacia, characterized by acquired hypophosphatemic rickets and renal phosphate wasting in association with specific tumors, is associated with[emedicine.medscape.com] The characteristics of this syndrome (ie, hypophosphatemia, renal phosphate wasting, low 1,25-dihydroxyvitamin D levels) and the fact that PHEX was identified as an endopeptidase[emedicine.medscape.com] phosphate transport.[emedicine.medscape.com]

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