Respiratory-muscle-weakness: Causes & Reasons

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Possible Causes for respiratory muscle weakness

Chronic Obstructive Pulmonary Disease

Age, respiratory muscle weakness, hypercapnia, hypoxia, malnutrition, treatment with corticosteroids or other agents, haemodynamic instability and activity limits due to respiratory [doi.org]

Respiratory muscle weakness Receptors. [dx.doi.org]

Ethical problems about the treatment of acute exacerbation of end-stage COPD are increasingly topical, especially in respiratory units and the ICU. [doi.org]

Acute Respiratory Distress Syndrome

That f/V T had a strong, inverse relationship to peak negative esophageal pressure also may reflect the influence of muscle weakness. acute lung injury acute respiratory distress [rc.rcjournal.com]

A recovering patient’s quality of life may be severely adversely affected by permanent damage to the lungs, respiratory problems, renal dysfunction, muscle weakness and depression [faron.com]

CONCLUSION: The characteristic rapid shallow breathing pattern in patients with ARDS/ALI occurs in the context of markedly diminished compliance, elevated respiratory drive [rc.rcjournal.com]

Duchenne Muscular Dystrophy

In this context, the most frequent respiratory complication is nocturnal and daytime hypoventilation related to respiratory muscle weakness. [ncbi.nlm.nih.gov]

Patients become wheelchair bound and develop respiratory muscle weakness. [stanfordhealthcare.org]

Some patients may need assisted ventilation to treat respiratory muscle weakness and a pacemaker for cardiac abnormalities. [ninds.nih.gov]

Opiate Overdose

Abstract Heroin and other opiates are central nervous system depressants; in an opiate overdose, respiration slows, potentially resulting in hypoxia, coma, or death. In 1998, 140 deaths from unintentional opiate overdoses occurred in King County (which includes Seattle). To characterize these deaths, public health[…] [ncbi.nlm.nih.gov]

Respiratory Muscle Paralysis

Respiratory muscle weakness first manifests as sleep-disordered breathing (SDB). [clinicaltrials.gov]

In addition, respiratory muscle weakness is often observed after stroke, contributing to exercise intolerance and a higher risk of poor outcome. [pnmedical.com]

Respiratory muscle weakness contributes to sleep-disordered breathing. [gbppa.org]

Heroin Dependence

Withdrawal symptoms of heroin can include: Intensive cravings Negative mood Stomach pain Nausea and vomiting Muscle aches and whole body pain Body weakness Joint pain Runny [acadianaaddiction.com]

[…] nose Nausea and vomiting Extreme sweating Chills Runny nose Increased blood pressure Cardiovascular problems Respiratory distress Insomnia Seizures Stroke Coma Death [acadianaaddiction.com]

Benzodiazepine Overdose

[…] infections Physical dependence Diplopia Ataxia Motor incoordination Muscle weakness Vertigo Headaches Changes in eating and sleeping patterns Cognitive Symptoms: Memory impairment [centerpointehospital.com]

weakness. [narconon.org]

[…] activities Forging prescriptions Increasing desire to be left alone Inability to meet expectations and responsibilities at work, school, or home Physical Symptoms: Increased respiratory [centerpointehospital.com]

Status Asthmaticus

When Sr Mg is 12 mg% loss of deep tendon reflexes, muscle weakness and respiratory depression. 55. [slideshare.net]

Hypokalemia can cause muscle weakness, which may worsen respiratory distress and cause cardiac arrhythmias. [emedicine.medscape.com]

Pulmonary Fibrosis

Neuromuscular disorders occur as the respiratory muscle weakness progresses. [web.archive.org]

Individuals with respiratory illnesses tend to have weak diaphragms because of difficulty breathing. Lie down on your back with your knees bent. [livestrong.com]

The cause of respiratory failure is often multifactorial and is secondary to spinal deformity, muscle weakness, disordered ventilatory control, sleep disordered breathing, [web.archive.org]

Amyotrophic Lateral Sclerosis

Respiratory muscle weakness and failure is a common complication late in the course of disease. [ncbi.nlm.nih.gov]

Weekly data downloads showed that disease progression was associated with increased respiratory muscle weakness, decreased spontaneous breathing, and increased use of non-invasive [ncbi.nlm.nih.gov]

Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle [ncbi.nlm.nih.gov]

Becker Muscular Dystrophy

Our cases became unable to walk in their teens, and were introduced to mechanical ventilation due to respiratory muscle weakness in their twenties and thirties. [ncbi.nlm.nih.gov]

Other complications Respiratory muscle weakness: Depending on the clinical severity of muscle weakness, this is a possible complication. [patient.info]

[…] expiratory muscle weakness, to assess selective weakness of specific respiratory muscle groups, and/or to delineate abnormalities in lung and chest wall mechanics. [clinicaladvisor.com]

Hypokalemia

Eleven patients had a history of recurring muscle weakness. All patients had quadraparesis (muscle weakness in all four limbs); in 10 patients the weakness was severe. [acutecaretesting.org]

Paraesthesiae Decreased reflexes Ascending paralysis Hypokalaemia Defined as potassium Signs and symptoms Generalised muscle weakness Respiratory depression Ascending paralysis [armandoh.org]

Involvement of cardiac or respiratory muscle can result in life-threatening arrhythmia or respiratory failure. [acutecaretesting.org]

Acute Hepatic Porphyria

weakness, numbness, respiratory failure Confusion, anxiety, seizures, hallucinations, fatigue Blistering lesions, erosions or ulcers of sun-exposed skin (with VP and HCP) [alnylam.com]

weakness, neuropathic pain in limbs, sensory loss, paralysis, fatigue, respiratory paralysis Autonomic2,4,10 nausea and vomiting, hypertension, tachycardia, constipation, [porphyria.ca]

[…] pain, tingling, numbness, weakness or paralysis confusion, hallucinations and seizures breathing difficulties (respiratory paralysis), possibly requiring ventilation reddish [britishlivertrust.org.uk]

Neonatal Respiratory Distress Syndrome

Both prophylactic and early surfactant replacement therapy, compared with later selective surfactant administration, reduce mortality and pulmonary complications in ventilated infants with respiratory distress syndrome (RDS). However, continued post-surfactant intubation and ventilation are risk factors for chronic[…] [ncbi.nlm.nih.gov]

Glycogen Storage Disease Type 2

Aspiration pneumonia; weakness of ventilatory muscles increases the risk of pneumonia. The adult form manifests with dystrophy and respiratory muscle weakness. [patient.info]

Some patients have presented with pulmonary (lung) insufficiency due to respiratory muscle weakness. [web.archive.org]

There may be limb-girdle weakness and weakness of respiratory muscles.[5] Signs Infantile form: Cardiomegaly and congestive heart failure. [patient.info]

Polymyositis

Dysphagia and neck flexor weakness can develop along with respiratory muscle weakness as the disease progresses. [ncbi.nlm.nih.gov]

Pulmonary involvement in polymyositis includes respiratory muscle weakness, aspiration pneumonia, interstitial lung disease, infection and drug-induced pneumonia. [ncbi.nlm.nih.gov]

The muscles may be tender and painful. 2) Respiratory muscle weakness, which may result in shortness of breath on exertion and occasionally respiratory failure. 3) Weakness [empendium.com]

Strychnine Poisoning

[…] rate; help recover from chronic alcoholism, drug addiction; remove muscle weakness, paresis and paralysis; will help with impotence functional nature. [en.intoxication-stop.com]

[…] increasing the tone of the bladder sphincter; they will aggravate hearing, smell, sight, especially color sensation; increase pressure, increase heart function, increase respiratory [en.intoxication-stop.com]

Dermatomyositis

dysphonia, dysphagia Less common: respiratory muscle weakness, visual changes, abdominal pain Systemic complications/association: Cardiomyopathy Cardiac conduction defects [physio-pedia.com]

The most common are proximal muscle weakness, dysphonia or dysphagia. Other possible symptoms include respiratory muscle weakness, visual changes and abdominal pain. [aafp.org]

Aspiration pneumonia secondary to respiratory muscle weakness Diffuse interstitial pneumonitis/fibrosis Large-bowel infarction secondary to vasculopathy has occurred in juvenile [physio-pedia.com]

Viral Pleurisy

Published July 28, 2010 by Question: What other health problems come with similar symptoms of pleurisy? Also I want to know symptoms and treatment for viral pleurisy? I have heard that it is contagious? Is that true? Answer: The lung is surrounded by a covering called pleura. Any inflammation in the pleura is known[…] [tandurust.com]

Spinal Muscular Atrophy

Progressive respiratory muscle weakness with bulbar involvement is the main cause of morbidity and mortality in type I and severe type II spinal muscular atrophy. [ncbi.nlm.nih.gov]

Respiratory muscle weakness frequently leads to pneumonia, which can be life threatening. [nationwidechildrens.org]

They have extremely weak muscle tone (hypotonia) at birth. Their respiratory muscles are very weak and they often do not survive past infancy due to respiratory failure. [ghr.nlm.nih.gov]

Myotonic Dystrophy

Children with congenital-onset DM1, once they survive the crucial neonatal period of respiratory muscle weakness with the help of assisted ventilation, usually show improvements [mda.org]

Breathing and swallowing muscle weakness Respiratory muscle weakness does not appear to be a common feature of DM2. [mda.org]

Congenital myotonic dystrophy is a severe form of this disorder, characterized by neonatal muscle hypotonia, feeding difficulties, respiratory muscle weakness, and an increased [icd10data.com]

Congenital Merosin-Positive Muscular Dystrophy

[…] tissue disease 0003198 Neck muscle weakness Floppy neck 0000467 Neonatal hypotonia Low muscle tone, in neonatal onset 0001319 Proximal muscle weakness Weakness in muscles [rarediseases.info.nih.gov]

muscle weakness—can prolong life expectancy. 18 A possible limitation of this study was the fact that histopathological and genetic testing was only performed for a few patients [ncbi.nlm.nih.gov]

In many congenital muscular dystrophy sub types, muscle weakness can increase with time and can lead to respiratory problems. [mobilephysiotherapyclinic.in]

CANOMAD Syndrome

paralysis of eye muscles, difficulty swallowing and speaking, and rarely respiratory muscle weakness. [malacards.org]

(ophthalmoplegia), difficulty swallowing, difficulty articulating words and, rarely, respiratory muscle weakness. [rarediseases.info.nih.gov]

Signs and symptoms of CANOMAD may include loss of muscle, tendon, and joint sensation, abnormal gait (walk), ataxia, tingling sensation on the skin around the mouth or extremities [malacards.org]

Cicuta Maculata Poisoning

Toxicon. 2011 Jan;57(1):157-61. doi: 10.1016/j.toxicon.2010.11.009. Epub 2010 Nov 20. Author information 1 USDA ARS Poisonous Plant Research Laboratory, 1150 E. 1400 N., Logan, UT 84341, USA. Kip.panter@ars.usda.gov Abstract It is well understood that water hemlock tubers are highly toxic to animals and to humans. However,[…] [ncbi.nlm.nih.gov]

Distal Spinal Muscular Atrophy Type 4

Etiology Pathophysiology Clinical features The most common causes of death among patients with SMA are respiratory insufficiency (due to respiratory muscle weakness ) and [amboss.com]

Respiratory dysfunction Progressive respiratory dysfunction may resulted due to respiratory muscle weakness due to loss of motor neurons in spinal cord.It may also causes [explainmedicine.com]

Symptoms vary in severity and may include muscle weakness and atrophy, fasciculations, emotional lability, and respiratory muscle weakness. [msdmanuals.com]

Hypercalcemia

We report a case of a 39-year-old female with active systemic lupus erythematosus who complained of lethargy and weakness with a moderate renal impairment. Hypercalcemia was confirmed by laboratory examination. Her X-ray revealed significant ectopic calcinosis in subcutaneous tissue of bilateral hands, and[…] [ncbi.nlm.nih.gov]

Spinal Muscular Atrophy Type 1

Most of these patients develop foot deformities, scoliosis, and respiratory muscle weakness. [mda.org]

Respiratory muscle weakness is generally the cause of death in children with type 1 or 2 SMA. Your child may need to be monitored for respiratory distress. [healthline.com]

They have extremely weak muscle tone (hypotonia) at birth. Their respiratory muscles are very weak and they often do not survive past infancy due to respiratory failure. [ghr.nlm.nih.gov]

Cyanogenic Glycoside

Open access peer-reviewed chapter By Islamiyat Folashade Bolarinwa, Moruf Olanrewaju Oke, Sulaiman Adebisi Olaniyan and Adeladun Stephen Ajala Submitted: April 27th 2016 Reviewed: July 13th 2016 Published: October 26th 2016 DOI: 10.5772/64886 Abstract Cyanogenic glycosides are natural plant toxins that are present[…] [dx.doi.org]

Congenital Muscular Dystrophy Type 1A

weakness, and muscle wasting (Tables 18.1 and 18.2). [link.springer.com]

A very common problem in children with MDC1A is weakness of the respiratory muscles, which results in frequent chest infections and poor breathing at night. [voorsara.nl]

Weak respiratory muscles make breathing difficult, and a number of children suffer from complications in the form of lung inflammation. [mediconvillage.se]

Conium Maculatum Poisoning

[…] tends to cause seizures, with death resulting from status epilepticus. [4] Poison hemlock toxicity is characerized by rapidly progressive muscle weakness and paralysis, which [emedicine.medscape.com]

[…] may eventuate in respiratory failure. [5] No antidote is available for either toxin. [emedicine.medscape.com]

With water hemlock toxicity, profuse salivation, perspiration, bronchial secretion, and respiratory distress leading to cyanosis develop soon after ingestion; severe toxicity [emedicine.medscape.com]