Responsiveness Decreasing: Causes & Reasons

Possible Causes for Responsiveness Decreasing

A low dosage of risperidone (0.5 mg b.i.d.) was well tolerated, however, and resulted in improvements in the patient's irritability and an apparently decreased response to [dx.doi.org]

Treatment response has been limited at best, with examples of each agent decreasing symptom burden but also potentially worsening dystonia and other abnormalities of movement [dx.doi.org]

Lorazepam, at a maximum dosage of 1 mg t.i.d., decreased the patient's level of agitation and somewhat improved his sleep. [dx.doi.org]

Multiple Mitochondrial Dysfunctions Syndrome Type 1

reduction of apoptosis and mitochondrial dysfunction, slowing of the cerebral excitatory cascade, decrease of local inflammatory response, reduction of free oxygen radicals [annalsofintensivecare.springeropen.com]

This may be in response to improving environmental conditions, although this has yet to be substantiated. [embomolmed.embopress.org]

[…] production, and decrease of vascular and membrane permeability. [annalsofintensivecare.springeropen.com]

Hypogonadotropic Hypogonadism Type 16

[…] in gonadotrope responsiveness. [clinicaltrials.gov]

Absence, decreased frequency or decreased amplitude of pulsatile GnRH release results in the clinical syndrome of hypogonadotropic hypogonadism (HH). [clinicaltrials.gov]

[…] demonstrated that pulsatile release of GnRH from the hypothalamus is a prerequisite for physiologic gonadotrope function, with continuous stimulation resulting in a paradoxical decrease [clinicaltrials.gov]

Asrar-Facharzt-Haque Syndrome

response to growth hormone stimulation test Hypergonadotropic hypogonadism Abnormality of the eye Arcus senilis Proptosis Abnormality of the genitourinary system Azoospermia [ncbi.nlm.nih.gov]

[…] defect Abnormality of the digestive system Hepatomegaly Hepatosplenomegaly IgG4-related retroperitoneal fibrosis Pancreatic hypoplasia Abnormality of the endocrine system Decreased [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 2T

[…] reflex response Decreased reflexes [ more ] 0001265 Impaired distal tactile sensation Decreased touch sensation in extremities 0006937 Impaired distal vibration sensation [rarediseases.info.nih.gov]

0003693 Distal muscle weakness Weakness of outermost muscles 0002460 EMG: chronic denervation signs 0003444 Hammertoe Hammer toe Hammertoes [ more ] 0001765 Hyporeflexia Decreased [rarediseases.info.nih.gov]

Neuroendocrine Prostate Neoplasm

[…] and decreases chromogranin A in patients with androgen ablation refractory prostate cancer. [link.springer.com]

Int 51(6):452–459 Article Google Scholar Franco DS, Alessandro S (2003) Combination therapie of ethinylestradiol and somatostatin analogue reintroduces objective clinical responses [link.springer.com]

Immunodeficiency Type 37

Eventually, these immune responses decrease if malnutrition persists. [es.slideshare.net]

T-cell production and function decrease in proportion to the severity of hypoproteinemia; however, specific antibody titers and immune responses to vaccines can be detected [es.slideshare.net]

Dominant Intermediate Charcot-Marie-Tooth Disease Type E

Deficient N-Hydroxylation of Amobarbital

Coadministration may decrease nirmatrelvir exposure resulting in reduced virologic response. [pdr.net]

Coadministration may result in decreased rilpivirine serum concentrations and impaired virologic response. [pdr.net]

Opioid-Induced Hyperalgesia

[…] reuptake and enhanced nociceptive response. [semanticscholar.org]

[…] being considered in the present review to explain OIH including; N-methyl-D-aspartate (NMDA) receptor activation; spinal dynorphin; descending facilitation; and finally decreased [semanticscholar.org]

Cone Rod Dystrophy Type 12

Additionally, full-field ERG showed decreased photopic and scotopic responses, attesting the damage of both cones and rods (Figure 2). [latunisiemedicale.com]

Decreased scotopic (A), photopic (B) and flicker (C) responses Figure 3. Karyotype. monosomy 45,X References 1. Jacobs PA, Browne C, Gregson N, Joyce C, White H. [latunisiemedicale.com]

Reduction in Two-Point Discrimination

There may be an increase or decrease in the distance between the points depending on the patient's response. [physio-pedia.com]

Cone Rod Dystrophy Type 17

Additionally, full-field ERG showed decreased photopic and scotopic responses, attesting the damage of both cones and rods (Figure 2). [latunisiemedicale.com]

Decreased scotopic (A), photopic (B) and flicker (C) responses Figure 3. Karyotype. monosomy 45,X References 1. Jacobs PA, Browne C, Gregson N, Joyce C, White H. [latunisiemedicale.com]

Autoimmune Lymphoproliferative Syndrome Type 2B

Decreased T cell activation MedGen UID: 339550 •Concept ID: C1846550 • Finding Decreased or impaired activation of T cells in response to a mitogen, cytokine, chemokine, cellular [ncbi.nlm.nih.gov]

Decreased circulating IgG level MedGen UID: 1720114 •Concept ID: C5234937 • Finding An abnormally decreased level of immunoglobulin G (IgG) in blood. [ncbi.nlm.nih.gov]

Abnormality of the digestive system Chronic diarrhea Abnormality of the immune system Asthma Complete or near-complete absence of specific antibody response to unconjugated [ncbi.nlm.nih.gov]

Orthostatic Syncope

Decreased baroreceptor responsiveness delays cardioacceleration and peripheral vasoconstriction in response to standing. [msdmanuals.com]

The sudden action of standing up might lead to an abnormal vasomotor response by causing sharp decreases in blood pressure and could result in hypoperfusion of tissues (particularly [symptoma.com]

[…] and a decrease in muscle tone, cardiac and vascular compliance. [ncbi.nlm.nih.gov]

Retinitis Pigmentosa 57

[…] or abolished responses as measured by electroretinography (ERG). [orpha.net]

[…] diagnosis of RP is based on peripheral visual field loss, pigment deposits in fundus, loss of photoreceptors at the optical coherence tomography (OCT) scan of the retina and decreased [orpha.net]

Cone Rod Dystrophy Type 8

Additionally, full-field ERG showed decreased photopic and scotopic responses, attesting the damage of both cones and rods (Figure 2). [latunisiemedicale.com]

Decreased scotopic (A), photopic (B) and flicker (C) responses Figure 3. Karyotype. monosomy 45,X References 1. Jacobs PA, Browne C, Gregson N, Joyce C, White H. [latunisiemedicale.com]

Witteveen-Kolk Syndrome

ORPHA:99826 Acrootoocular Syndrome Microcephaly, Decreased response to growth hormone stimulation test ORPHA:2980 Coffin-Siris Syndrome 9 Microcephaly, Decreased response [mousephenotype.org]

ORPHA:139507 Ritscher-Schinzel Syndrome 1 Decreased response to growth hormone stimulation test, Adrenal hypoplasia OMIM:220210 Cohen Syndrome Microcephaly, Decreased response [mousephenotype.org]

ORPHA:1855 Pycnodysostosis Cerebral dysmyelination, Decreased response to growth hormone stimulation test, Decreased serum i... [mousephenotype.org]

Congenital Disorder of Glycosylation Type 1X

It seems that compound heterozygosity for p.R141H and some other mutations in PMM2 gene (e.g. p.F119L) is responsible for the decreased PMM2 activity, inadequate for normal [biochemia-medica.com]

Charcot-Marie-Tooth Disease Type 2N

[…] reflex response Decreased reflexes [ more ] 0001265 Peripheral axonal atrophy 0003384 Pes cavus High-arched foot 0001761 Pes planus Flat feet Flat foot [ more ] 0001763 Sensory [rarediseases.info.nih.gov]

[…] formation 0001810 Foot dorsiflexor weakness Foot drop 0009027 Foot osteomyelitis Foot bone infection 0001886 Hammertoe Hammer toe Hammertoes [ more ] 0001765 Hyporeflexia Decreased [rarediseases.info.nih.gov]

Spinocerebellar Ataxia

[…] muscle tone Low muscle tone [ more ] 0001290 Gliosis 0002171 Head titubation 0002599 Hyporeflexia Decreased reflex response Decreased reflexes [ more ] 0001265 Incoordination [rarediseases.info.nih.gov]

[…] reflex response Decreased reflexes [ more ] 0001265 Late onset 0003584 Nystagmus Involuntary, rapid, rhythmic eye movements 0000639 5%-29% of people have these symptoms Hearing [rarediseases.info.nih.gov]

[…] reflex response Decreased reflexes [ more ] 0001265 Impulsivity Impulsive 0100710 Limb ataxia 0002070 Microsaccadic pursuit 0007792 Parkinsonism 0001300 Postural tremor 0002174 [rarediseases.info.nih.gov]

Hypertrophy of the Adrenal Cortex

[…] resulting from hypertrophy of the adrenal cortex include hyperglycemia, decreased immunity, decreased allergic response alarm reaction responses resulting from increased [quizlet.com]

Atrophy is a decrease in cell size or decrease in cell number (apoptosis) in response to a decreased level of stress placed on the cells Now that you have finished this video [stomponstep1.com]

IMMUNE SYSTEM: DECREASE MACROPHAGE RESPONSES TO M. I. F. DECREASE RECEPTORS NUMBER TO I gE www.freelivedoctor.com 18. [slideshare.net]

Granulosis Rubra Nasi

The authors believe that inflammation around sweat ducts are responsible for decreased sweating and hence, vesicle formation- findings in the late stage of GRN. [ncbi.nlm.nih.gov]

Patient was counseled regarding the disease and poor response to treatment. [ncbi.nlm.nih.gov]

On follow up after three weeks, size of the vesicles had decreased and patient stated no increase in size of the vesicles, even on sun exposure. [ncbi.nlm.nih.gov]

Cone Rod Dystrophy Type 6

Additionally, full-field ERG showed decreased photopic and scotopic responses, attesting the damage of both cones and rods (Figure 2). [latunisiemedicale.com]

Decreased scotopic (A), photopic (B) and flicker (C) responses Figure 3. Karyotype. monosomy 45,X References 1. Jacobs PA, Browne C, Gregson N, Joyce C, White H. [latunisiemedicale.com]

Chilblain Lupus Erythematosus

Calcineurin inhibitors, such as tacrolimus (Prograf™) or mycophenolate mofetil (CellCept®), decrease inflammation by lowering your immune system response. [my.clevelandclinic.org]

Antimalarial agents, such as hydroxychloroquine (Plaquenil®), fight fatigue, reduce inflammation and decrease joint pain. [my.clevelandclinic.org]

Steroid ointments, such as fluocinolone acetonide (Synalar®) or hydrocortisone butyrate (Locoid®), decrease swelling and lower inflammation. [my.clevelandclinic.org]

Respiratory Acidosis

Hypoventilation in COPD involves multiple mechanisms, including decreased responsiveness to hypoxia and hypercapnia, increased ventilation-perfusion mismatch leading to increased [en.wikipedia.org]

Hypoventilation in COPD involves multiple mechanisms, including the following: Decreased responsiveness to hypoxia and hypercapnia Increased ventilation-perfusion mismatch [emedicine.com]

[…] dead space ventilation, and decreased diaphragm function secondary to fatigue and hyperinflation. [en.wikipedia.org]

Amodiaquine Allergy

It is known that this disease responsible for the death of approximately a million people annually is caused by parasites that are injected into the bloodstream by infected [healthjockey.com]

It was further suggested that boosting the treatments with a single dose of primaquine drug can decrease malaria transmission from treated patients and be a hallmark in elimination [healthjockey.com]

Childhood Absence Seizures

[…] event onset, followed by small fMRI decreases. [ncbi.nlm.nih.gov]

This time course differed markedly from the hemodynamic response function (HRF) model used in conventional fMRI analysis, consisting of large increases beginning after electrical [ncbi.nlm.nih.gov]

In contrast, we observed small early fMRI increases in the orbital/medial frontal and medial/lateral parietal cortex >5 s before seizure onset, followed by profound fMRI decreases [ncbi.nlm.nih.gov]

Lycoperdonosis

Lycoperdonosis is generally treated with corticosteroids, which decrease the inflammatory response; these are sometimes given in conjunction with antimicrobials. [translation.babylon.com]

Lycoperdonosis is generally treated with corticosteroids, which decrease the inflammatory response; these are sometimes given in conjunction with antimicrobials.The disease [en.wikipedia.org]

Febrile Infection-Related Epilepsy Syndrome

However, hypothermia has reported an acceptable response and fewer sequelae (36). [revistas.unal.edu.co]

Electroconvulsive therapy (ECT), as described by Mirás-Veiga et al. (37) in one patient, also showed a decreased epileptiform activity. [revistas.unal.edu.co]

During the chronic phase, one study assessed six patients treated with KD for a period between 6 months and 2 years, with a marked decrease in the frequency of seizures and [revistas.unal.edu.co]