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73 Possible Causes for Restrictive Ventilatory Defect, Vacuolization

  • Oculo-Pharyngo-Distal Myopathy

    Muscular dystrophy changes with rimmed vacuoles were the main histopathological changes.[] Myopathological findings showed rimmed vacuoles with varying degrees of muscular dystrophic changes.[] Histological features included basophilic-rimmed vacuoles, but the typical OPMD intranuclear filaments were absent.[]

  • Hereditary Mucoepithelial Dysplasia

    Papanicolaou smears show lack of epithelial cell maturation, poikilocytosis, anisocytosis, large paranuclear cytoplasmic vacuoles, and cytoplasmic strand-shaped inclusions[] ventilatory defect Increased antibody level in blood Premature graying of hair Pulmonary fibrosis Recurrent fractures Flared metaphysis Phimosis Neonatal respiratory distress[] Vaginal, oral, and urinary cytological smears show a lack of epithelial cell maturation, large paranuclear cytoplasmic vacuoles, and cytoplasmic strand-shaped inclusions.[]

  • Lipid Pneumonia

    The lung biopsy specimen disclosed organisms within lipid vacuoles in the areas of lipid pneumonia, while caseating granulomas, the usual tissue reaction to pathogenic mycobacteria[] ventilatory defect.[] BAL analysis showed a marked reduction in the total number of alveolar macrophages; almost 70% of these cells contained intracytoplasmic lipid vacuoles.[]

  • Zebra Body Myopathy

    0006785 5 waddling gait 60 33 hallmark (90%) Very frequent (99-80%) HP:0002515 6 emg: myopathic abnormalities 60 33 hallmark (90%) Very frequent (99-80%) HP:0003458 7 rimmed vacuoles[] ventilatory defect Hip dislocation Macroglossia Knee flexion contracture Ankle contracture Myositis Progressive Unsteady gait Growth delay Intellectual disability Myalgia[] 0003236 5 limb-girdle muscular dystrophy 59 32 hallmark (90%) Very frequent (99-80%) HP:0006785 6 waddling gait 59 32 hallmark (90%) Very frequent (99-80%) HP:0002515 7 rimmed vacuoles[]

  • Pulmonary Alveolar Microlithiasis

    The vacuolated subapical area and the tight junctions in the margins clearly identify these cells as ATII cells ( 21 ).[] Pulmonary functions showed hyperinflation and small airways dysfunction in one case besides the presence of restrictive ventilatory defect.[] The patient, 28 weeks pregnant, was rehospitalized 10 months after the diagnosis, presenting hypoxemic acute respiratory failure and severe restrictive ventilatory defect[]

  • Polymyositis

    KEYWORDS: anti-Ku antibody; dropped head syndrome; rimmed vacuole; scleroderma-polymyositis overlap syndrome[] Interstitial lung disease (ILD), defined as radiological signs on chest x ray examination/HRCT or restrictive ventilatory defect, were found in 11 (65%) patients and were[] Arahata and Engel state that all their patients with a diagnosis of inclusion body myositis had the typical histological findings, including vacuoles and filamentous inclusions[]

  • Right Ventricular Dilatation

    The mechanism of myocardial injury is related to degeneration and atrophy of myocardial cells, with loss of myofibrils and cytoplasmic vacuolization.[] The patients were grouped according to the severity of the restrictive ventilatory defect: mild (FVC, 65 to 80 percent predicted), moderate (FVC, 51 to 64 percent predicted[]

  • Pulmonary Alveolar Proteinosis

    Pneumocystis pneumonia - exudates foamy & vacuolated. Pulmonary hemorrhage (acute). (???) Mycobacterial infection. Nocardia infection. Images PAP - low mag.[] Pulmonary function shows a restrictive ventilatory defect. X-rays show bilateral patchy to extensive consolidations, and bronchial lavage yields a milky fluid.[] Pulmonary-function testing showed a moderately restrictive ventilatory defect, with a forced vital capacity of 54% and a diffusion capacity of 37% of the predicted values.[]

  • Interstitial Pulmonary Fibrosis of the Newborn

    Diagnosis can generally be confirmed by BAL findings (staining of lipid vacuoles in the alveolar macrophages) and the findings of transbronchial or surgical lung biopsy. -[] Restrictive lung diseases (or restrictive ventilatory defects [1] ) are a category of extrapulmonary, pleural, or parenchymal respiratory diseases that restrict lung expansion[] ventilatory defect and/or impaired gasventilatory defect and/or impaired gas exchange, and persistence of theseexchange, and persistence of these findings for 3 months withfindings[]

  • Mucopolysaccharidosis 4A

    Scale bar, 1 μm. ( C, D ) Cytoplasmic vacuoles appear with dense granular contents or empty after extraction or release of contents.[] ventilatory defect Stiff lung or chest wall causing decreased lung volume 0002091 Scoliosis Abnormal curving of the spine 0002650 Ulnar deviation of the wrist 0003049 Wide[] Keywords: CHO Cells; Lysosomes; Vacuoles; Animals; Rabbits; Humans; Mucopolysaccharidosis VI; N-Acetylgalactosamine-4-Sulfatase; Recombinant Proteins; Antibodies; Antibodies[]

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