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42 Possible Causes for Retinal Pigment Epithelial Mottling

  • Cancer-Associated Retinopathy

    Visual acuity (VA) measured 20/20 both eyes (BE) and fundus examination revealed bilateral macular retinal pigment epithelial (RPE) mottling with patches of atrophy in the[] […] arteriolar attenuation, retinal pigment epithelial mottling and optic disc pallor. 20 , 21 Goldman visual field testing can identify a generalized depression or a central[] Macular OCT demonstrated areas of outer retinal segment and RPE atrophy and fine sub-RPE drusen BE (Figure B).[]

  • Central Serous Chorioretinopathy

    Dilated fundus examination revealed bilateral retinal pigment epithelium mottling, focal pigment epithelial detachments within the macula, and inferior serous retinal detachments[] However, it is now recognized that CSCR may present with diffuse retinal pigment epithelial dysfunction (eg, diffuse retinal pigment epitheliopathy, chronic CSCR, decompensated[] RPE) characterized by neurosensory retinal detachment overlying areas of RPE atrophy and pigment mottling.[]

  • Esotropia

    pigment epithelial mottling Need help with a diagnosis?[] Ophthalmoplegia Paravenous chorioretinal atrophy X-linked inheritance X-linked recessive inheritance Blindness Myopia Perisylvian polymicrogyria Language impairment Polymicrogyria Retinal[]

  • Choroiditis

    Usually there is resolution of the fundus findings, although careful fundus evaluation sometimes shows some residual fine retinal pigment epithelial mottling.[] This condition is characteristically inactive, with overlying retinal pigment epithelial (RPE) mottling or atrophy and no subretinal fluid.[] Occasionally, activity is found with features of subretinal fluid, possible exudation, and overlying retinal edema.[]

  • Familial Benign Flecked Retina

    Pigmentary changes with retinal pigment epithelial mottling may be seen in children with cystinosis , which is caused by mutations in the CTNS gene.[]

  • Fleck Retina of Kandori

    Pigmentary changes with retinal pigment epithelial mottling may be seen in children with cystinosis , which is caused by mutations in the CTNS gene.[]

  • Nephropathic Cystinosis

    Pigmentary changes with retinal pigment epithelial mottling, seen as early as infancy, were the most common posterior segment manifestations.[]

  • Cone Rod Dystrophy 10

    The ophthalmoscopic exam may initially have a normalappearing macula, progressing to retinal pigment epithelial mottling, eventually developing into a ‘‘bull’s-eye’’ maculopathy[] However, Electroretinogram (ERG) demonstrating loss of photopic function or Ocular Coherence Tomography (OCT) showing thinning of the macula and Retinal Nerve Fiber Layer[]

  • Acute Zonal Occult Outer Retinopathy

    Fundus examination of her right eye revealed a zone of retinal pigment epithelial (RPE) mottling extending from the optic nerve head.[] At time of presentation, fundus photos of the right and left eyes showed subtle retinal pigment epithelial mottling to the nasal fovea in the right eye and the entire fovea[]

  • Osteoporosis-Oculocutaneous Hypopigmentation Syndrome

    pigment epithelial mottling Retinal arteriolar tortuosity Abnormal basal ganglia MRI signal intensity Abnormal visual field test Corticospinal tract atrophy Sensorineural[] […] cortical atrophy Dementia Proximal muscle weakness Sensory neuropathy Kyphosis Muscle cramps Constriction of peripheral visual field Mitochondrial inheritance Myoclonic spasms Retinal[]

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