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502 Possible Causes for Rheumatoid Arthritis, Sore Mouth, T Cell Activation Increased

  • Sjögren Syndrome

    Rheumatoid arthritis (RA) is frustrating enough on its own.[everydayhealth.com] Human exposure to an extremely high dose of TCDD in vivo induced a selective increase in the frequency of T cells producing IL-22 but not IL-17, IL-10, or IFN-γ ( 69 ).[doi.org] Other symptoms may include: Contact lens discomfort Dry sinuses and frequent sinus infections or nosebleeds Sore mouth, tongue or throat Difficulty chewing or swallowing Dry[allaboutvision.com]

  • Systemic Scleroderma

    arthritis (RA), and dermatitis (DE) (109 cases) as a control.[ncbi.nlm.nih.gov] Levels of IL-4 are elevated in the sera of patients with SSc ( 83 ), and the number of IL-4–producing T cells is increased in their peripheral blood ( 84, 85 ).[jci.org] 0200042 Telangiectasia of the skin 0100585 Xerostomia Dry mouth Dry mouth syndrome Reduced salivation [ more ] 0000217 5%-29% of people have these symptoms Abnormal bowel[rarediseases.info.nih.gov]

  • Celiac Disease

    Individuals with celiac disease cannot outgrow the disease since it is a lifelong autoimmune disorder like diabetes and rheumatoid arthritis.[massgeneral.org] APC presents the toxic peptide to CD4 T cells. Activated gluten-reactive CD4 T-cells produce high levels of pro-inflammatory cytokines.[doi.org] […] problems such a canker sores or dry mouth seizures tingling numbness in the hands and feet tiredness weak and brittle bones Adults who have digestive symptoms with celiac[web.archive.org]

  • Behçet Disease

    Golimumab is a novel fully human anti-TNF-α monoclonal antibody that has been approved for the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis[ncbi.nlm.nih.gov] Different ethnic populations show increased T- and B-cell responses to these proteins and hence HSPs may be pathophysiologically related to the development of Behcet’s syndrome[symptoma.com] , Mouth Sores, Behcets, Behcet Type: Phase 3 Drug Trial Target: 204 Participants Study Info Study Locations Sending Send SMS with Study Info: SMS Sent![studypages.com]

  • Hypersensitivity

    CASE PRESENTATION: A 77-year-old African American woman with a history of rheumatoid arthritis presented with progressively worsening shortness of breath and nonproductive[ncbi.nlm.nih.gov] These sores can be found on the genitals, vagina, anus, rectum, lips and mouth. Pregnant women can transmit the disease to their unborn child.[niaid.nih.gov] However, increased activation of CD4 T-cell and CD8 T-cells was only observed following four days of DDAB exposure.[ncbi.nlm.nih.gov]

  • Stomatitis

    Rheumatoid arthritis. Lancet 2001;358:903-11. 8. Nakazaki S, Murayama T, Katoh S.[cjhr.org] Denture Sore Mouth (Denture-Related Stomatitis) Denture sore mouth is also known as sore mouth under plates, chronic denture palatitis, stomatitis prosthetica, denture-related[exodontia.info] […] of natural killer cells in various stages of disease [43] Increased adherence of neutrophils Reduced quantities and functionality of regulatory T cells in lesional tissue[emedicine.medscape.com]

  • Discoid Lupus Erythematosus

    Previously, a discoid lupus erythematosus-like eruption linked to its use was rarely reported in patients with rheumatoid arthritis.[ncbi.nlm.nih.gov] Mouth ulcers Formation of thick scales may spread to the interior region of the mouth, causing open sores or oral ulcers.[phaa.com] Intracellular calcium is increased in activated T cells and binds to calmodulin, which activates calcineurin, a calcium-activated phosphatase.[academic.oup.com]

  • Lupus Erythematosus

    arthritis (RA), as well as many of the drugs in the therapeutic pipeline, reduce the autoimmune inflammatory process but lead to a general immunosuppression.[stm.sciencemag.org] cell activation and suppression of intercellular adhesion molecule expression by T cells ; selective down-regulation of B cells ; increasing CD95 sensitivity of activated[en.wikipedia.org] Oral ulcers (open mouth sores). Arthritis, pain, inflammation, or swelling of the joints.[webmd.com]

  • Food Allergy

    Arthritis Systemic Lupus Multiple Sclerosis Neurological Headache Fatigue Insomnia Irritability Depression Anxiety Migraine Gastrointestinal Vomiting Diarrhea Bloating Infantile[foodallergy.com] Memory T cells are increased in frequency and have distinct activation requirements and cell-surface proteins that distinguish them from armed effector T cells 10-25.[ncbi.nlm.nih.gov] […] defects of permanent teeth Adults are less likely to have digestive signs and symptoms and may instead have one or more of the following: anemia bone or joint pain canker sores[web.archive.org]

  • Idiopathic Neutropenia

    Neutropenia, Splenomegaly and Rheumatoid arthritis.[rcpa.edu.au] […] throat mouth sores that keep returning toothache skin rashes tiredness flu-like symptoms Occasionally, infections can lead to a life-threatening condition called sepsis.[nhs.uk] The percentage of activated T-lymphocytes was increased in patients' BM as indicated by the proportions of human leucocyte antigen (HLA)-DR( ), CD25( ), CD38( ), CD69( ) and[ncbi.nlm.nih.gov]

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