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69 Possible Causes for Rheumatoid Arthritis, Systemic Autoinflammation

  • Vasculitis

    A patient with a history of rheumatoid arthritis presented with bilateral orbital lesions while on abatacept.[ncbi.nlm.nih.gov] To date, several cases of systemic lupus erythematosus, Aicardi-Goutieres syndrome, familial chilblain lupus, retinal vasculopathy-cerebral leukodystrophy have been reported[ncbi.nlm.nih.gov] The best described of these is vasculitis occurring as a complication of rheumatoid arthritis (see below).[nras.org.uk]

  • Uveitis

    arthritis Systemic lupus erythematosus Sarcoidosis Ankylosing spondylitis Juvenile rheumatoid arthritis / Juvenile idiopathic arthritis Inflammatory bowel disease Wegener[medicine.yale.edu] Autoinflammation may simply be defined as self-directed tissue inflammation, where local factors at disease-prone sites determine activation of the innate immune system.[doi.org] Patients with classical autoimmune connective tissue disease (N 17) suffered mostly from rheumatoid arthritis and granulomatosis with polyangiitis and exhibited predominantly[ncbi.nlm.nih.gov]

  • Calcium Pyrophosphate Arthropathy

    CPPD crystal deposition disease in patients with rheumatoid arthritis. Clin Rheumatol 2006; 25:468–469. 3.[err.eg.net] -associated antibody deficiency-immune dysregulation Autoinflammatory syndrome Autoinflammatory syndrome of childhood Autosomal systemic lupus erythematosus Behçet disease[se-atlas.de] (e.g. rheumatoid arthritis) or septic arthritis.[bpac.org.nz]

  • Systemic Scleroderma

    arthritis (RA), and dermatitis (DE) (109 cases) as a control.[ncbi.nlm.nih.gov] Lupus erythematosus, vasculopathy, instead of autoinflammation, appears to be clinically important in systemic scleroderma.[ncbi.nlm.nih.gov] Management of leg ulcers in patients with rheumatoid arthritis or systemic sclerosis: The importance of concomitant arterial and venous disease.[revistas.unal.edu.co]

  • Pericarditis

    CONCLUSION: Rheumatoid arthritis may cause CP with no symptoms. Pericardiectomy could be a promising therapy for CP.[ncbi.nlm.nih.gov] More recently, there has been evidence that the innate immune system and autoinflammation contribute to acute and recurrent pericarditis. [6, 7] Chronic idiopathic pericarditis[emedicine.com] Examples of such disorders include lupus, scleroderma, and rheumatoid arthritis.[web.archive.org]

  • Juvenile Rheumatoid Arthritis

    […] in joint Pauciarticular onset juvenile chronic arthritis acute juvenile rheumatoid arthritis juvenile chronic polyarthritis monarticular juvenile rheumatoid arthritis pauciarticular[wikidata.org] Schneider, Systemic Juvenile Idiopathic Arthritis, Pediatrics in Systemic Autoimmune Diseases, 10.1016/B978-0-444-63596-9.00003-7, (53-84), (2016). Christian M.[doi.org] […] mellitus; JCA juvenile chronic arthritis; JIA juvenile idiopathic arthritis; JRA juvenile rheumatoid arthritis; MHC major histocompatibility complex; RA rheumatoid arthritis[doi.org]

  • Behçet Disease

    Golimumab is a novel fully human anti-TNF-α monoclonal antibody that has been approved for the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis[ncbi.nlm.nih.gov] Ahmet Gül, Behçet Disease, Textbook of Autoinflammation, 10.1007/978-3-319-98605-0_35, (647-665), (2019).[doi.org] Further work suggested that the BS associated variant of STAT4 is not related to the previously reported one associated with autoimmune diseases such as rheumatoid arthritis[ncbi.nlm.nih.gov]

  • Pyoderma

    Keywords : Pyoderma gangrenosum; phagédénisme géométrique; Inflammatory bowel disease; rheumatoid arthritis.[scielo.sa.cr] The dominant hypothesis is that altered innate immunity leads to systemic autoinflammation ( 5 ).[frontiersin.org] For instance, ulcerative colitis, rheumatoid arthritis, and multiple myeloma (MM) have all been associated with pyoderma gangrenosum.[en.wikipedia.org]

  • Pyoderma Gangrenosum

    Rheumatoid arthritis is a systemic autoimmune disease resulting in joint destruction and deformities, but also associated with extraarticular and systemic manifestations.[ncbi.nlm.nih.gov] OBJECTIVES: To determine a specific genetic background related to autoinflammation for PG.[ncbi.nlm.nih.gov] […] in general. 43 Our study suggests that 2 other important systems, the Fas/Fas L system and the CD40/CD40 ligand system, may contribute to tissue damage and inflammation in[journals.lww.com]

  • Sweet Syndrome

    arthritis.[nejm.org] French, Autoinflammation behind the curtain, British Journal of Dermatology, 178, 3, (581-582), (2018). Pedro Secchin, Maria K. Gomes, Danielle C.[doi.org] It may be associated with hematologic diseases, including leukemia, with immune diseases as rheumatoid arthritis, or can occur in isolation.[ncbi.nlm.nih.gov]

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