Rheumatoid Factor Positive: Causes & Reasons

Possible Causes for Rheumatoid Factor Positive

She had a stable state of rheumatoid factor positive RA and had a history of multiple intravitreal injections placed in the symptomatic right eye due to age-related macular [ncbi.nlm.nih.gov]

[…] such as male sex and rheumatoid factor positivity. [ncbi.nlm.nih.gov]

For rheumatoid factor-positive (RF+) RA, summary OR for ever, current and past smokers were 3.02 (2.35 to 3.88), 3.91 (2.78 to 5.50) and 2.46 (1.74 to 3.47), respectively. [ncbi.nlm.nih.gov]

Sjögren Syndrome

factor (RF)-positive, as well as positive for other auto-antibodies (SSA and SSB). [rheumatoidarthritis.net]

positive anti-La/SSB antibodies (p = 0.077), positive rheumatoid factor (p = 0.034), and immunoglobulin G levels > 1600 mg/dL (p = 0.077). [ncbi.nlm.nih.gov]

In addition, patients with pSS with positive rheumatoid factors tend to express a higher level of IL-17 than patients with negative rheumatoid factors. [ncbi.nlm.nih.gov]

Mixed Connective Tissue Disease

factor positive 43 (30) ANA, antinuclear antibody T able 1. [academic.oup.com]

Active disease was associated with higher anti-ribonucleoprotein antibody titres at follow-up and positive rheumatoid factor (RF) at diagnosis and follow-up. [ncbi.nlm.nih.gov]

factor, anti-citrullinated antibodies – often positive Differential Diagnosis Other connective tissue diseases SLE Inflammatory myopathies Sjögren syndrome Systemic sclerosis [arupconsult.com]

Systemic Scleroderma

Markers Serological markers include 3 : elevated erythrocyte sedimentation rate (ESR) rheumatoid factor (RF): positive in 30-40% antinuclear antibodies (ANA): 35-96% anti [radiopaedia.org]

Rheumatoid factor is positive in one third of patients. [merckmanuals.com]

Granulomatosis with Polyangiitis

Blood tests showed elevated levels of C-reactive protein, positive rheumatoid factor, and proteinase 3-anti-neutrophil cytoplasmic antibody. [ncbi.nlm.nih.gov]

A normocytic anemia, leukocytosis, elevated erythrocyte sedimentation rate, positive rheumatoid factor and ANCA (specifically PR3-ANCA) are often shown on serology. [jacpjournal.org]

A positive test result for rheumatoid factor occurs in 50-60% of patients with granulomatosis with polyangiitis and can be misleading because this normally indicates rheumatoid [dermnetnz.org]

Glomerulonephritis

She had a history of severe, deforming rheumatoid factor (RF)-positive arthritis since age 7, and had undergone multiple surgical reconstructions of the knee and foot joints [academic.oup.com]

They may also have a positive antinuclear antibody and rheumatoid factor tests (70%) and positive cryoglobulins (75%).23 The pathogenesis of MCGN is obscure but probably involves [pmj.bmj.com]

[…] double-stranded DNA), cryoglobulinemia (rheumatoid factor, cryoglobulin), endocarditis (blood cultures, echo if appropriate), and post infectious GN (ASO titers for pharyngitis [clinicaladvisor.com]

Systemic Lupus Erythematosus

An association with rheumatoid arthritis is suggested by the fact that one-quarter of those with SLE have positive serological tests for rheumatoid factor, and perhaps as [britannica.com]

Other helpful tests include C3 and C4 complement component (elevated levels may be predictive for glomerulonephritis in SLE), rheumatoid factor (may be positive or negative [clinicaladvisor.com]

Churg-Strauss Syndrome

[…] immunity, elevated immunoglobulin E (IgE) levels and rheumatoid factor [ 6 ]. [jmedicalcasereports.com]

All subjects were negative for rheumatoid factor and ANCAs. [erj.ersjournals.com]

Etiology is considered to be autoimmune due to allergic symptoms, immune complex mediation 48% are (ANCA, antineutrophil cytoplasmic antibody) positive, increased T-cell mediated [jmedicalcasereports.com]

Dermatomyositis

Auto-antibodies A variety of auto-antibodies are associated with the disease and include Antinuclear Autoantibodies (ANA), Rheumatoid Factor (RF), and more specific myositis-associated [pathwaymedicine.org]

Electromyography (EMG) EMGs are often positive although these studies, along with muscle biopsies, are increasingly being replaced by MRIs. [pathwaymedicine.org]

Polyarticular Juvenile Idiopathic Arthritis

Rheumatoid factor tests are always positive and anitnuclear antibodies may also be present. [orpha.net]

Here we describe a 9-year-old girl with rheumatoid factor (RF)-positive polyarticular JIA, not sJIA, combined with pneumonia who was successfully treated by plasma exchange [ncbi.nlm.nih.gov]

Rheumatoid factor-positive polyarthritis is defined as the presence of arthritis affecting five or more joints at disease onset and by detection of rheumatoid factor in two [orpha.net]

Juvenile Idiopathic Arthritis

Polyarthritis can be rheumatoid factor-positive or negative. [arthritis.org]

Rhematoid Factor positive is also referred to as Early Onset Adult Rheumatoid Arthritis. [youtube.com]

Polyarticular arthritis-rheumatoid factor positive: arthritis in five or more joints during the first six months of disease with rheumatoid factor. [everydayhealth.com]

Juvenile Seronegative Polyarthritis

Individuals with this condition also have a positive blood test for proteins called rheumatoid factors. [icdlist.com]

Factor may be positive Positive Rheumatoid Factor confers similar presentation to Rheumatoid Arthritis in adults Systemic (Still's Disease) High daily Relapsing Fever >39 [fpnotebook.com]

There is a later onset and chances of a positive result with Rheumatoid factor. [news-medical.net]

Psoriatic Juvenile Idiopathic Arthritis

Factor Positive — Polyarthritis, Juvenile, Rheumatoid Factor Negative — Oligoarthritis, Juvenile — Juvenile Oligoarthritis — Enthesitis-Related Arthritis, Juvenile — Arthritis [mesh.kib.ki.se]

factor positive with polyarticular and enthesitis-related arthritis. [rheumatologynetwork.com]

Polyarthritis can be rheumatoid factor-positive or negative. [arthritis.org]

Seronegative Arthritis

And actually when you're first diagnosed, it's probably less than 50% have the rheumatoid factor positive so those, it's the rheumatoid factor when we're talking about seropositivity [sharecare.com]

[…] with and without rheumatoid factor positivity at entry and identification of variables correlating with outcome. [link.springer.com]

Though seronegative RA is where the test, the serone test for rheumatoid arthritis is negative, the rheumatoid factor is positive in 70% or 80% of people after they've had [sharecare.com]

Systemic Juvenile Idiopathic Arthritis

Only one subtype of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood [hon.ch]

Factor Negative Polyarthritis, Juvenile, Rheumatoid Factor Positive Psoriatic Arthritis, Juvenile Rheumatoid Arthritis, Juvenile Still Disease, Juvenile Onset Still Disease [decs.bvs.br]

Enthesitis-Related Arthritis Juvenile Idiopathic Arthritis Juvenile Oligoarthritis Juvenile Onset Still Disease Juvenile Onset Stills Disease Juvenile Psoriatic Arthritis Juvenile Rheumatoid [decs.bvs.br]

Rheumatoid Nodule

Around 90% of all patients with RA and rheumatoid nodules test positive for rheumatoid factor. [news-medical.net]

General Seen in rheumatoid arthritis - usually only in seropositive cases, i.e. rheumatoid factor (RF) positive. [1] Exceptions are reported. [2] Gross Usually on the extensor [librepathology.org]

Classic rheumatoid nodules are seen in nearly 20% to 25% of patients who test positive for Rheumatoid factor and have classic symptoms of RA. [news-medical.net]

Felty Syndrome

It only occurs in patients who are both rheumatoid factor positive and positive for anticyclic citrullinated peptide antibodies. [gponline.com]

On examination she had, in addition, fever, positive rheumatoid factor, reversible swan-neck deformity of the fingers but otherwise normal joint findings. [ncbi.nlm.nih.gov]

All patients were positive for rheumatoid factor and five were anti CCP positive. All patients presented bone erosions, three had splenomegaly. [ncbi.nlm.nih.gov]

Enthesitis-Related Arthritis

Two subtypes are recognized: polyarticular rheumatoid factor negative JIA and polyarticular rheumatoid factor positive disease. [eurotmj.com]

Tests for rheumatoid factor (immune system proteins that may attack healthy tissue) are negative Polyarthritis-rheumatoid factor positive Polyarthritis-rheumatoid factor positive [childrens.com]

Polyarthritis can be rheumatoid factor-positive or negative. [arthritis.org]

Palindromic Rheumatism

Rheumatoid factor and anti-CCP were highly correlated: in 18 patients who were anti-CCP positive, 10 of them were also rheumatoid factor positive. [hopkinsarthritis.org]

Rheumatoid factor in 46.4% and anti-cyclic citrullinated peptide in 42% of the cases were positive. [ncbi.nlm.nih.gov]

Risk factors to this appear to be rheumatoid factor positivity, female sex, and involvement of the hands. [hopkinsarthritis.org]

Oligoarthritis

Rheumatoid factor positive polyarticular juvenile idiopathic arthritis (also known as polyarthritis, rheumatoid factor positive) causes inflammation in five or more joints [ghr.nlm.nih.gov]

Some of the main clinical features of JIA include systemic arthritis, oligoarthritis rheumatoid factor, negative and positive polyarthritis, and enthesitis-related arthritis [medical-dictionary.thefreedictionary.com]

Treatment The treatment of extended oligoarticular juvenile idiopathic arthritis is much like that of rheumatoid factor positive or rheumatoid factor negative polyarticular [verywellhealth.com]

Cryoglobulinemia

Rheumatoid factor positivity warrants further diagnostic testing. [healio.com]

Rheumatoid factor -- positive in types II and III. Skin biopsy -- may show inflammation in blood vessels, vasculitis. [account.allinahealth.org]

Many HCV-infected patients with cryoglobulinemia are misdiagnosed with rheumatoid arthritis due to rheumatoid factor positivity. [healio.com]

Cryoglobulinemic Vasculitis

Rheumatoid factor positivity warrants further diagnostic testing. [healio.com]

Rheumatoid factor -- positive in types II and III. Skin biopsy -- may show inflammation in blood vessels, vasculitis. [ufhealth.org]

Many HCV-infected patients with cryoglobulinemia are misdiagnosed with rheumatoid arthritis due to rheumatoid factor positivity. [healio.com]

Polyarthritis

If an antibody called rheumatoid factor is present in the blood, the polyarthritis is rheumatoid factor-positive (RF-positive). [myhealth.alberta.ca]

Polyarthritis can be rheumatoid factor-positive or negative. [arthritis.org]

- Negative rheumatoid factor, positive HLA-B27 antigen. - Synovial fluid is often very inflammatory with > 25,000 leukocytes and may even appear purulent. [tcd.ie]

Idiopathic Cryoglobulinemia

Rheumatoid factor positivity warrants further diagnostic testing. [healio.com]

Cutaneous vasculitis and rheumatoid factor positivity as presenting signs of hepatitis C virus-induced mixed cryoglobulinemia. Arch Dermatol. 1995 Oct. 131(10):1119-23. [emedicine.medscape.com]

Mixed cryoglobulins are cold-precipitable rheumatoid factors (RFs), with the serum often being positive when standard assays for IgM antiglobulin activity are used. [asmscience.org]

Juvenile Ankylosing Spondylitis

Two tests for rheumatoid factor, taken three months apart, are positive. [verywell.com]

Polyarticular (rheumatoid factor positive and rheumatoid factor negative)-JIA affecting five or more joints. [jointhealth.org]

These are: polyarticular JIA – rheumatoid factor negative polyarticular JIA – rheumatoid factor positive. [betterhealth.vic.gov.au]

Rheumatoid Lung Disease

She had a low-positive rheumatoid factor, and was started on prednisone. [hopkinsarthritis.org]

According to Johnson, the main risk factors for RA-ILD are advancing age, male sex, greater RA disease activity, rheumatoid factor (RF) positivity, and elevated titers of [mdmag.com]

In 2005, she developed a rheumatoid distribution of synovitis, and her CCP and rheumatoid factor were positive. She was started on methotrexate in March, 2005. [hopkinsarthritis.org]

Undifferentiated Juvenile Idiopathic Arthritis

It is formed by 7 subtypes of chronic arthritis of unknown etiology that debut in < 16 years (oligoarthritis, polyarthritis with positive rheumatoid factor, polyarthritis [ibecs.isciii.es]

Erosive Arthropathy

Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor. [ncbi.nlm.nih.gov]

[…] arthritis sometimes rheumatoid factor (RF) positive usually proximal, bilateral and symmetric involvement: metacarpophalangeal joints, proximal interphalangeal joints, and [radiopaedia.org]

[…] interphalangeal joints, 1st carpometacarpal joint 6, but not the metacarpophalangeal (MCP) joints and large joints classic central erosions (gull-wing appearance); possible ankylosis rheumatoid [radiopaedia.org]

Juvenile Seropositive Polyarthritis

Most adults with rheumatoid arthritis do have a positive rheumatoid factor. [cincinnatichildrens.org]

Rheumatoid factor (RF) test: May show up in children with polyarthritis. A positive rheumatoid factor may signal more serious disease. [arthritis.org]

If you have seropositive RA, you have a positive rheumatoid factor or anti-CCP blood test result. [healthline.com]

Ectodermal Dysplasia with Natal Teeth Type Turnpenny

factor-negative juvenile idiopathic arthritis Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis Scleroderma Severe hemophilia A Severe hemophilia B Symptomatic [se-atlas.de]

[…] due to a constitutional platelet anomaly Rare hemorrhagic disorder due to a constitutional thrombocytopenia Rare hemorrhagic disorder due to a qualitative platelet defect Rheumatoid [se-atlas.de]