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308 Possible Causes for Round Face, Splenomegaly

  • Mucopolysaccharidosis

    […] trunk (dwarfism), dysplasia (abnormal bone size and/or shape) and other skeletal irregularities, thickened skin, enlarged organs such as liver (hepatomegaly) or spleen (splenomegaly[en.wikipedia.org]

  • Mucopolysaccharidosis 2

    Individuals with this disorder may experience the following signs: abnormal retina, heart murmur and leaky heart valves, enlarged liver (hepatomegaly) enlarged spleen (splenomegaly[secure.ssa.gov] […] degenerative joints causing joint stiffness Spinal cord defects Sleep disorder such as sleep apnea Decrease in mental cognition Enlarged liver (hepatomegaly) and enlarged spleen (splenomegaly[dovemed.com] […] loss [ 30 ], decreased pulmonary function and obstructive sleep apnoea [ 31 ], frequent and recurrent respiratory infections, cardiac disease [ 32 , 33 ], hepatomegaly and splenomegaly[rheumatology.oxfordjournals.org]

  • Liver Cirrhosis

    We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[ncbi.nlm.nih.gov] face ("chipmunk cheeks") Enlarged abdomen Inability to sleep Mood swings Hand tremors (shaking) Acne Steroid dependency Note: Patients must never stop or reduce the prednisone[emedicinehealth.com] Esophageal varices and splenomegaly regressed after 3 and 8 years of sustained virologic responses in cases 1 and 2, respectively.[ncbi.nlm.nih.gov]

  • Rheumatoid Arthritis

    It is extremely rare for RA to present as FS or develop after initially presenting as neutropaenia and splenomegaly.[ncbi.nlm.nih.gov] These side effects are serious and can include easy bruising, thinning of the bones (osteoporosis), cataracts, weight gain, a round face, susceptibility to infections, diabetes[orthop.washington.edu] Other: thyroid disorders, osteoporosis, depression, splenomegaly.[patient.info]

  • Persistent Polyclonal B-cell Lymphocytosis

    Abstract Five cases of persistent polyclonal B-cell lymphocytosis (PPBL) with progressive splenomegaly are reported; three were splenectomized.[ncbi.nlm.nih.gov] Contributions from many leading surgical pathologists give you well-rounded, expert answers to any question that you may face.[books.google.com] […] negative lymphocytosis, the presence of binucleated lymphocytes in peripheral blood, and a polyclonal increase in serum immunoglobulin-M that may occasionally be accompanied by splenomegaly[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    […] keratoconjunctivitis sicca as well as more uncommon manifestations Haematologic manifestations, including cytopenias, thrombophilia, thromboembolic disease, lymphadenopathy and splenomegaly[els.net] Depending on the dosage, people who require steroids may develop Cushing's syndrome, symptoms of which may include obesity, puffy round face, diabetes mellitus, increased[en.wikipedia.org] Enlargement of the spleen (splenomegaly) occurs in about 10% of people.[msdmanuals.com]

  • Hepatosplenic Lymphoma

    Splenectomy was performed due to progressive splenomegaly.[adc.bmj.com] Contributions from many leading surgical pathologists give you well-rounded, expert answers to any question that you may face.[books.google.com] It occurs mainly in young adults presenting with splenomegaly and most often with hepatomegaly but without lymphadenopathy.[bloodjournal.org]

  • Sjogren's Syndrome

    On admission, she presented with anemia, elevated C-reactive protein levels, anasarca, and hepato-splenomegaly.[ncbi.nlm.nih.gov] Possible side effects may include easy bruising, thinning of bones, cataracts, weight gain, a round face, diabetes and high blood pressure.[medicalmarijuana.com] […] development of NHL lymphoma include low complements (C3 and C4), presence of cryoglobulins, low CD4:CD8 ratio, persistence of unilateral or bilateral parotid gland enlargement, splenomegaly[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] Depending on the dosage, people who require steroids may develop Cushing's syndrome, symptoms of which may include obesity, puffy round face, diabetes mellitus, increased[en.wikipedia.org] […] relapsing illness, with a variety of different presentations. [ 5, 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info]

  • Aagenaes Syndrome

    […] and symptoms: Main signs and symptoms include abdominal pain , acholic stools, fatigue , hepatomegaly, hyperlipidemia , lymphedema, nausea , vomiting , multiple lipomas , splenomegaly[xpertdox.com] Short stature, round face, and hypertelorism. Cervical hypermotility and odontoid subluxation.[accessanesthesiology.mhmedical.com] […] skin pigmentation Abnormality of pigmentation Pigmentary changes Pigmentary skin changes Pigmentation anomaly [ more ] 0001000 Multiple lipomas Multiple fatty lumps 0001012 Splenomegaly[rarediseases.info.nih.gov]

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