Possible Causes for rugger jersey spine Primary Myelofibrosis Primary myelofibrosis (PMF) is a clonal hematopoietic stem cell disorder. It is characterized by bone marrow fibrosis, extramedullary hematopoiesis with hepatosplenomegaly and leukoerythroblastosis in the peripheral blood. The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[…] [ncbi.nlm.nih.gov] Renal Osteodystrophy The "rugger jersey" spine occurring in the usual osteosclerosis of renal osteodystrophy has been consistently absent in this variant. [ncbi.nlm.nih.gov] Plain radiographs of the lumbosacral spine showed sclerosis of the upper and lower thirds of the vertebral bodies giving the "rugger - jersey" spine. [smjonline.org] […] in 60% with dense end-plates produce appearance of rugger-jersey (rugger jersey spine) Rugger-jersey spine in Renal osteodystrophy o Also in pelvis, ribs, long bones, facial [learningradiology.com] Autosomal Dominant Osteopetrosis Type 2 jersey" spine may be cause of anemia (d/t obliterated marrow space) Cf: pyknodysostosis Camurati-Engelmann disease Charles E. [gamuts.net] The spine images show the classic sandwich vertebrae sign (differentiate by some from the rugger jersey spine). [roentgenrayreader.blogspot.com] Radiographically, sclerosis predominates, in several sites, including the spine (vertebral end-plate thickening, or Rugger-Jersey spine), the pelvis (“bone-within-bone” structures [hindawi.com] Primary Hyperoxaluria 30% of the patients suffering from hyperoxaluria type 1 are diagnosed only when they already had reached end-stage renal disease. We report the case of a 57-year-old woman with history of chronic kidney failure presenting with paraplegia due to spinal cord compression by thoracic mass-like lesions. Bone biopsy[…] [ncbi.nlm.nih.gov] Primary Hyperoxaluria Type 1 Experiencia en la evaluación de pacientes con litiasis urinaria en Panamá. Resumen Resumen: Mediante un estudio retrospectivo, no randomizado, se evaluaron 23 pacientes tratados por litiasis urinaria siguiendo un protocolo de evaluación metabólica. A 22 de los 23 se les detectó por lo menos un factor de riesgo para[…] [revistamedica.org] Primary Hyperparathyroidism Jersey spine Rugger Jersey spine Fig. 10 Rugger Jersey spine Soft tissue calcification Vascular calcification References [ edit ] Hyperparathyroidism by Adam Myhre, M.D., [en.wikibooks.org] Skeletal survey revealed valgus deformity of knee joints, bilateral subluxation of upper femoral epiphysis(SUFE), epiphyseal displacement of bilateral humeri, rugger jersey [ncbi.nlm.nih.gov] A skeletal survey revealed evidence of epiphyseal displacement of bilateral humeral heads, rugger jersey spine and subperiosteal bone resorptions involving lateral aspects [bmcendocrdisord.biomedcentral.com] Primary Hyperoxaluria Type 3 Review Heart failure with mitral valve regurgitation due to primary hyperoxaluria type 1: case report with review of the literature Luc Van Driessche et al. Acta Cardiol. 2007 Apr. Abstract Primary hyperoxaluria type I (PH I) is a rare recessive autosomal disorder characterized by systemic calcium oxalate[…] [pubmed.ncbi.nlm.nih.gov] Primary Hyperoxaluria Type 2 2016 May;590(10):1467-76. doi: 10.1002/1873-3468.12181. Epub 2016 May 10. Affiliations PMID: 27096395 DOI: 10.1002/1873-3468.12181 Free article Cellular degradation of 4-hydroxy-2-oxoglutarate aldolase leads to absolute deficiency in primary hyperoxaluria type 3 Julia R MacDonald et al. FEBS Lett. 2016 May. Free article[…] [pubmed.ncbi.nlm.nih.gov] Osteomesopyknosis Spine X-ray was taken which showed sclerotic change of spine endplate and pelvic bone. Rugger-jersey vertebra and sandwich vertebra was shown ( Fig. 1 ). [synapse.koreamed.org] A radiograph of spine revealed rugger-jersey vertebra and sandwich vertebra. [synapse.koreamed.org] Rugger-jersey spine, the major radiologic finding in our case, can be seen in autosomal dominant osteopetrosis (ADO). [synapse.koreamed.org] Autosomal Recessive Osteopetrosis Type 6 Note the band-like sclerosis of the vertebral endplates (rugger jersey spine) and the inhomo- geneous sclerosis at the metadiaphyses of the distal femora, tibiae and fibulae [iofbonehealth.org] […] the metaphysis of long bones leads to a funnel-like appearance ("erlenmeyer flask" deformity). [10] Sclerosis of vertebral end plates results in "sandwich vertebrae" and "rugger-jersey [wajradiology.org] " spine. [10] MIOP may be complicated by rickets. [wajradiology.org] Acquired Osteosclerosis […] in 60% with dense end-plates produce appearance of rugger-jersey (rugger jersey spine) Rugger-jersey spine in Renal osteodystrophy o Also in pelvis, ribs, long bones, facial [learningradiology.com] Jersey Spine in Renal Osteodystrophy. [learningradiology.com] Renal Osteodystrophy Rugger-Jersey Spine · Constellation of musculoskeletal abnormalities occurring with chronic renal failure featuring some combination of o Osteomalacia [learningradiology.com] Osteopetrosis Skeletal survey showed generalized increased bone density, sclerosed medulary space, Rugger-Jersey spine and diploic space filled with dense materials. [ncbi.nlm.nih.gov] jersey" spine may be cause of anemia (d/t obliterated marrow space) Cf: pyknodysostosis Camurati-Engelmann disease Charles E. [gamuts.net] Common radiographic features include a generalized sclerosis, rugger jersey spine, and endobone formation. [journals.lww.com] Autosomal Recessive Osteopetrosis Type 7 Lateral view of the dorsal spine of a 28-year-old woman with typical sandwich-structure, or Rugger-Jersey spine. Figure 2: Case 1. [healio.com] Radiographically, sclerosis predominates, in several sites, including the spine (vertebral end-plate thickening, or Rugger-Jersey spine), the pelvis (“bone-within-bone” structures [hindawi.com] […] the metaphysis of long bones leads to a funnel-like appearance ("erlenmeyer flask" deformity). [10] Sclerosis of vertebral end plates results in "sandwich vertebrae" and "rugger-jersey [wajradiology.org] Osteitis Fibrosa Cystica […] in 60% with dense end-plates produce appearance of rugger-jersey (rugger jersey spine) Rugger-jersey spine in Renal osteodystrophy o Also in pelvis, ribs, long bones, facial [learningradiology.com] […] tuberosity Trochanters Inferior surface of calcaneus and clavicle Intracortical resorption Cigar/oval shaped radiolucency in the cortex Terminal tuft erosion in phalanges Rugger-jersey [boneandspine.com] Jersey Spine in Renal Osteodystrophy. [learningradiology.com] Atypical Pneumonia Radiographically, sclerosis predominates, in several sites, including the spine (vertebral end-plate thickening, or Rugger-Jersey spine), the pelvis (“bone-within-bone” structures [hindawi.com] B, Almost 3-month-old infant with classic radiograph findings of ADO, including diffuse osteosclerosis and the appearance of a rugger-jersey spine. [academic.oup.com] Bollerslev and Andersen Jr. reported striking radiographic findings like diffuse systemic osteosclerosis, “rugger jersey spine,” and “bone-within-bone appearance” in the pelvis [hindawi.com] Rare Hyperparathyroidism […] showing rugger jersey spine Fig. 5 X ray hands showing sub periosteal resorption involving 2nd, 3rd middle phalanges Fig. 6 Tc 99 Sestamibi scan showing abnormal, persistent [bmcendocrdisord.biomedcentral.com] Skeletal survey revealed bilateral SUFE with bilateral genu valgum, displacement of epiphysis of bilateral humeri, rugger jersey spine and sub periosteal bone resorption involving [bmcendocrdisord.biomedcentral.com] Skeletal survey revealed valgus deformity of knee joints, bilateral subluxation of upper femoral epiphysis(SUFE), epiphyseal displacement of bilateral humeri, rugger jersey [bmcendocrdisord.biomedcentral.com] Osteosclerosis Plain radiographs of the lumbosacral spine showed sclerosis of the upper and lower thirds of the vertebral bodies giving the "rugger - jersey" spine. [smjonline.org] (known as the “rugger jersey spine”) or, less common, as a diffuse pattern (fig.1). [posterng.netkey.at] The rugger jersey spine sign. Radiology 2004;230:491-2. 11. Kalyvas D, Tosios KI, Leventis MD, Tsiklakis K, Angelopoulos AP. [smjonline.org] Diabetic Autonomic Neuropathy Radiographically, sclerosis predominates, in several sites, including the spine (vertebral end-plate thickening, or Rugger-Jersey spine), the pelvis (“bone-within-bone” structures [hindawi.com] B, Almost 3-month-old infant with classic radiograph findings of ADO, including diffuse osteosclerosis and the appearance of a rugger-jersey spine. [academic.oup.com] Bollerslev and Andersen Jr. reported striking radiographic findings like diffuse systemic osteosclerosis, “rugger jersey spine,” and “bone-within-bone appearance” in the pelvis [hindawi.com] Lytic Bone Lesion jersey spine osteopenia brown tumors salt and pepper sign in the skull (pepper pot skull) chondrocalcinosis Findings in secondary (and tertiary) hyperparathyroidism are often [radiopaedia.org] […] associated with the osteosclerosis of renal osteodystrophy and the osteomalacia of vitamin D deficiency: subperiosteal bone resorption osteopenia osteosclerosis, e.g. rugger-jersey [radiopaedia.org] spine soft tissue calcification superscan : generalized increased uptake on Tc- 99 m pertechnetate bone scan (focal uptake with adenoma) superior and inferior rib notching [radiopaedia.org] Leontiasis Ossium Plain radiographs of the lumbosacral spine showed sclerosis of the upper and lower thirds of the vertebral bodies giving the "rugger - jersey" spine. [smjonline.org] The classic manifestation is the so called “ rugger jersey ” spine, because of the characteris- tic vertebral endplate sclerosis (4). [researchgate.net] The rugger jersey spine sign. Radiology 2004;230:491-2. 11. Kalyvas D, Tosios KI, Leventis MD, Tsiklakis K, Angelopoulos AP. [smjonline.org] Hyperparathyroidism jersey spine osteopenia brown tumors salt and pepper sign in the skull (pepper pot skull) chondrocalcinosis Findings in secondary (and tertiary) hyperparathyroidism are often [radiopaedia.org] […] incidental finding, as x-ray is not a routine diagnostic tool Cortical thinning : especially prominent in the phalanges of the hand (acroosteolysis) Salt-and-pepper skull Rugger-jersey [amboss.com] […] associated with the osteosclerosis of renal osteodystrophy and the osteomalacia of vitamin D deficiency: subperiosteal bone resorption osteopenia osteosclerosis, e.g. rugger-jersey [radiopaedia.org] Secondary Hyperparathyroidism jersey spine osteopenia brown tumors salt and pepper sign in the skull (pepper pot skull) chondrocalcinosis Findings in secondary (and tertiary) hyperparathyroidism are often [radiopaedia.org] […] incidental finding, as x-ray is not a routine diagnostic tool Cortical thinning : especially prominent in the phalanges of the hand (acroosteolysis) Salt-and-pepper skull Rugger-jersey [amboss.com] […] associated with the osteosclerosis of renal osteodystrophy and the osteomalacia of vitamin D deficiency: subperiosteal bone resorption osteopenia osteosclerosis, e.g. rugger-jersey [radiopaedia.org] Leontiasis due to Leprosy Findings in secondary (and tertiary) hyperparathyroidism are numerous: sub periosteal bone resorption, osteopenia, osteosclerosis e.g. rugger-jersey spine, soft tissue calcification [file.scirp.org] Osteopathia Striata spine, ? [orthopaedicsone.com] […] dominant type (Albers-Schonberg disease)(most asympto-matic) (40% with pathologic fx) Type I: cranial vault osteosclerosis (high incidence of conductive hearing loss) Type II: rugger-jersey [orthopaedicsone.com] Spondyloenchondrodysplasia The cranial vault is diffusely thickened ſt, and the vault and skull base are extremely dense. b) Lateral radiograph depicts rugger jersey spine. [de.slideshare.net] Type 1-marked thickening of the sclerotic skull vault with normal spine. Type 2-a sclerotic skull base & a rugger jersey spine with high risk of fracture. [authorstream.com] Rugger-jersey spine describes the prominent subendplate densities at multiple contiguous levels to produce an alternating sclerotic-lucent-sclerotic appearance. [de.slideshare.net] Acroosteolysis jersey” spine); resorption of the distal tufts and radial side of the digits is characteristic Neurotrophic disease ( p. 606 ) Bone resorption secondary to diabetes, leprosy [radiologykey.com] […] soft-tissue and vascular calcification; vertebrae appear osteopenic with characteristic, homogeneous, radiodense bands traversing horizontally at each end of the vertebrae (“rugger [radiologykey.com] Osteomalacia Lateral radiograph of the spine in a patient with chronic renal failure reveals characteristic endplate sclerosis (arrows) referred to as rugger-jersey spine. [emedicine.medscape.com] […] common in adults than in children; - patients may have findings of osteomalacia / renal osteodystrophy such as decreased mineralization, coarsened texture of the bones, "rugger-jersey [wheelessonline.com] " appearance of spine, and, occasionally, bowed long bones; - most of these patients have chronic renal disease; - Histologic examination: - biopsy: - biopsy is frequently [wheelessonline.com] Eating Disorder Radiographically, sclerosis predominates, in several sites, including the spine (vertebral end-plate thickening, or Rugger-Jersey spine), the pelvis (“bone-within-bone” structures [hindawi.com] Bollerslev and Andersen Jr. reported striking radiographic findings like diffuse systemic osteosclerosis, “rugger jersey spine,” and “bone-within-bone appearance” in the pelvis [hindawi.com] Del Fattore et al. reported generalised osteosclerosis in 43% of the cases, rugger jersey spine was noted in 52.3% of the patients, and 33.3% patients had bone-in-bone appearance [hindawi.com] X-Linked Osteoporosis with Fractures Subperiosteal resorption (arrows) in the fingers of a child with renal osteodystrophy Sclerosis is noted adjacent to the endplates (rugger-jersey spine) in a patient with [rad.washington.edu] AV Block Mobitz II B, Almost 3-month-old infant with classic radiograph findings of ADO, including diffuse osteosclerosis and the appearance of a rugger-jersey spine. [academic.oup.com]
