Saddle Nose: Causes & Reasons

Possible Causes for Saddle Nose

For nasal fracture presenting saddle nose deformity, the nasal septum was fixed with the frontal process of the maxillary bone by Kirschner wire. [ncbi.nlm.nih.gov]

Saddle Nose Deformity Saddle nose deformity occurs when cartilage in the nose dies and disintegrates. As a result, the bridge of the nose sags in the middle. [msdmanuals.com]

Otherwise, there were no complications such as saddle nose, canthal dystopia, canthal webbing, or nasolacrimal outflow obstruction. [ncbi.nlm.nih.gov]

Relapsing Polychondritis

We describe here a case of sarcoidosis that presented with saddle nose resembling relapsing polychondritis. [ncbi.nlm.nih.gov]

Complications include saddle-nose deformity/joint deformity, vertigo, tinnitus, pulmonary infection, laryngotracheobronchial stricture, scleritis or iritis, epiglottitis, [visualdx.com]

It is characterized by inflammation and degeneration of cartilage and can result in deformities such as floppy ear and saddle nose. [fpnotebook.com]

Granulomatosis with Polyangiitis

Saddle nose reconstruction in GPA patients with minimal or no local disease is a safe procedure despite an increased rate of revision surgery. [ncbi.nlm.nih.gov]

Ear, nose and throat symptoms are present in 50-95% (persistent nasal obstruction, destructive sinusitis, crusting and/or hemorrhagic rhinitis, nasal septum deformity, saddle [orpha.net]

Overall, saddle nose reconstruction in GPA patients is safe even if an increased rate of revision surgery has to be expected compared with individuals without GPA undergoing [ncbi.nlm.nih.gov]

Rothmund-Thomson Syndrome

Roth·mund syn·drome ( rot'mūnd ), atrophy, pigmentation, and telangiectasia of the skin, usually with juvenile cataract, saddle nose, congenital bone defects, disturbance [medical-dictionary.thefreedictionary.com]

Clinical description The skeletal abnormalities may be overt (such as frontal bossing, saddle nose and congenital radial ray defects), and/or subtle anomalies visible only [orpha.net]

Synopsis hereditary dermatosis atrophy pigmentation telangiectasia juvenile cataract saddle nose congenital bone defects disturbances of hair growth hypogonadism. growth deficiency [humpath.com]

CINCA Syndrome

Saddle back nose, frontal bossing, short hands and feet with finger clubbing are the peculiar morphologic characteristics seen. [indianpediatrics.net]

nose. [ncbi.nlm.nih.gov]

The principal clinical signs in our child with CINC syndrome clockwise. (1) Clubbing (2) Skin rash (3) Saddle nose (4) Patellar overgrowth. Fig. 2. [indianpediatrics.net]

Laron Syndrome

They had typical appearance features of Laron syndrome such as short stature and obesity, with protruding forehead, saddle nose, large eyes, sparse and thin silky hair and [ncbi.nlm.nih.gov]

Other features include hypoplasia of the base of the skull with small face and mandible, delayed closure of the fontanels, saddle nose, hypotrichosis, delayed dentition, tooth [whonamedit.com]

Upon examination she was noted to have protruded forehead, thin hair, small hands and feet, and a saddle nose. [alliedacademies.org]

Tertiary Syphilis

Nasal deformity, in the form of depression of nose, gradually worsened and developed into a saddle, associated with redness over nose and surrounding area. [peertechz.com]

Ulcers in these areas may cause destruction of the bony and cartilaginous structures (saddle nose) or perforations that sometimes persist despite treatment. [clinicaladvisor.com]

Later manifestations of congenital syphilis include bone and teeth deformities, such as “saddle nose” (due to destruction of the nasal septum), “saber shins” (due to inflammation [emedicine.medscape.com]

Syphilis

[…] triad A50.54 Late congenital cardiovascular syphilis A50.55 Late congenital syphilitic arthropathy A50.56 Late congenital syphilitic osteochondropathy A50.57 Syphilitic saddle [icd10data.com]

nose A50.59 Other late congenital syphilis, symptomatic A50.6 Late congenital syphilis, latent A50.7 Late congenital syphilis, unspecified A50.9 Congenital syphilis, unspecified [icd10data.com]

Congenital Syphilis

nose and scars at the angles of the mouth. [medical-dictionary.thefreedictionary.com]

Untreated early syphilis infections results in a high risk of poor pregnancy outcomes, including saddle nose, lower extremity abnormalities, miscarriages, premature births [en.wikipedia.org]

nose Perioral fissures Diagnosis : VDRL FTA-ABS Treatment : Penicillin G See Also : Syhilis Torches infections [medlibes.com]

Spondyloepimetaphyseal Dysplasia Type SPONASTRIME

nose, frontal bossing, and relatively large head. [ncbi.nlm.nih.gov]

Craniofacial: large head, frontal bossing, epicanthal folds, midface hypoplasia, broad and anteverted “saddle” nose is characteristic, mild prognathism. [accessanesthesiology.mhmedical.com]

[…] sponastrime dysplasia: familial short-limb dwarfism with saddle nose, spine alterations and metaphyseal striation Helv Paediatr Acta 1983 [semanticscholar.org]

Late Congenital Syphilis

The saddle nose deformity was due to the failure of development of nasal bones. [ijstd.org]

Clinical examination showed the "saddle-nose" deformity, Hutchinson's teeth, high-arched palate, Dubois little-finger sign, and small maxillae resulting in shallow depression [ncbi.nlm.nih.gov]

Deafness (8 th Nerve) Interstitial Keratitis Lymphadenopahy Autoimmune Haemolytic anemia Osteochondritis and Metaphysitis Glaucoma Pseudoparalysis of parrot (Painful limbs) Saddle [mediconotebook.com]

Nose Surgery

Repeated violent blows on the organ cause a saddle nose to develop. [beauty-pro.org]

Rhinoplasty can be used to alter or improve the following: Saddle nose Oversized nose Crooked tip Crooked nasal base Drooping tip Hump Bulbous tip Rhinoplasty Consultation [buckinghamfacialplastics.com]

Accidents and direct traumas can also change the shape, the classic example would be the boxer’s nose. [beauty-pro.org]

Leprosy

BACKGROUND: Facial deformation as a sequela of leprosy is caused not only by a saddle nose but also by regression of the maxilla, as well documented in paleopathological observations [ncbi.nlm.nih.gov]

[…] mixed peripheral neuropathy (often with resultant injuries) +/- hypoesthesia/paresthesia +/- neuralgia peripheral nerve thickening, which may be palpable corneal ulcers saddle-nose [radiopaedia.org]

The bone involvement may also lead to gross deformation of the nose skeleton and ensuing creation of a saddle-nose deformity. [news-medical.net]

Axenfeld-Rieger Syndrome Type 3

[…] deformity Saddle nose Ski jump nose [ more ] 0011120 Cryptorchidism Undescended testes Undescended testis [ more ] 0000028 Ectopia pupillae Displaced pupil 0009918 Growth [rarediseases.info.nih.gov]

[…] chambers [ more ] 0001631 Autosomal dominant inheritance 0000006 Blindness 0000618 Cerebellar vermis hypoplasia 0001320 Concave nasal ridge Boxer's nasal deformity Boxer's nose [rarediseases.info.nih.gov]

Lethal Midline Granuloma

Saddle-nose deformity and cauliflower ear are frequent complications. Laryngeal involvement is rare. [headnecksurgery.wordpress.com]

Hunermann-Conradi Syndrome

The severe form is characterised by marked congenital rhizomelic dwarfism, flexion contractures of large joints, small chest and saddle nose deformity. [ijri.org]

The disorder recognized by Hünermann also included micromelia, a saddle nose deformity, flexion contractures, cataracts, and a dermopathy. [mhmedical.com]

However, all three can share systemic manifestations such as short necks, frontal bossing, saddle noses, high arched palates and hypertelorism. [healio.com]

Mucopolysaccharidosis

Definition: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase ( IDURONIDASE ) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity[…] [hon.ch]

Perforated Nasal Septum

SEPTAL PERFORATION AND SADDLE NOSE DEFORMITY / NASAL DEFORMITY Large septal perforations may cause structural compromise of the nose (deviation of the septum, saddle nose [perforatedseptum.com]

If the perforation is very large, the structure of the nose can become unstable and the tip of the nose can droop, this is called a “saddle nose.” [masseyeandear.org]

There are various grading systems to saddle nose deformity. However the majority can be corrected in a one-stage procedure as a day case patient. [nosereconstruction.co.uk]

Deviated Nasal Septum

The overall incidence of complications was septal perforation in 10 cases (5%), adhesions in 14 cases (7%), recurrence of symptoms or deformity in 12 cases (6%), saddle nose [ncbi.nlm.nih.gov]

congenital Excludes 1: dentofacial anomalies [including malocclusion] (M26.-) syphilitic saddle nose (A50.5) [aapc.com]

Risk factors for intraoperative saddle nose deformity in septoplasty patients. [verywellhealth.com]

Mucopolysaccharidosis Type 2

COMPASSIONATE ALLOWANCE INFORMATION MPS II - HUNTER SYNDROME ALTERNATE NAMES Mucopolysaccharidosis type II; Iduronate sulfatase deficiency; MPS Disorder; MPS II; I2S Deficiency; Lysosomal Storage Disease – Mucopolysaccharidosis Type II DESCRIPTION MPS II – Hunter syndrome is a rare, inherited disease in which the[…] [secure.ssa.gov]

Moebius Syndrome

Citation, DOI, disclosures and article data Citation: Gaillard F, Deng F, Rasuli B, et al. Möbius syndrome. Reference article, Radiopaedia.org (Accessed on 27 Mar 2023) https://doi.org/10.53347/rID-1711 Möbius syndrome, also known as congenital facial diplegia syndrome, is a rare congenital condition characterized by the[…] [radiopaedia.org]

Congenital Malformation

The absence of inferior vena cava (IVC) is one among infrequent subtypes of IVC abnormalities that are rarely seen in general population. The absence of IVC involves either that of entire IVC or that of infrarenal segment. These two entities are relatively similar but their etiopathogeneses are still controversial.[…] [ncbi.nlm.nih.gov]

Oculocerebrorenal Syndrome

Song, E., Luo, N., Alvarado, J. A., Lim, M., Walnuss, C., Neely, D., ... Sun, Y. (2017). Ocular Pathology of Oculocerebrorenal Syndrome of Lowe: Novel Mutations and Genotype-Phenotype Analysis. Scientific Reports, 7 (1), [1442]. https://doi.org/10.1038/s41598-017-01447-3 Ocular Pathology of Oculocerebrorenal Syndrome of Lowe[…] [indiana.pure.elsevier.com]

Mucocutaneous Leishmaniasis

Midline destructive lesions have multiple possible etiologies, which can be grouped into neoplastic, infectious, or vasculitis-associated. The purpose of these case reports and literature review was to highlight the need to include mucocutaneous leishmaniasis in the diagnosis of midfacial lesions in any patient who has[…] [ncbi.nlm.nih.gov]

Chondritis of the External Ear

The nose is often afflicted as well and can deteriorate into a flattened nose bridge called saddle nose. [medical-dictionary.thefreedictionary.com]

Nose cartilage involvement/saddle nose Granulomatosis with polyangiitis, leishmaniasis, congenital syphilis, leprosy aspergillosis, paracoccidioidomycosis, Cocaine inhalation [en.wikipedia.org]

nose鞍鼻 salivary gland 唾液腺 salivation唾液分泌 semicircular canal 半規管 senile deafness老人性難聴 sensorineural hearing loss 感音難聴 sensory organ感覚器 sialoadenitis唾液腺炎 sinobronchial syndrome [tokyo-med.ac.jp]

Ectodermal Dysplasia

Appearances of nail dystrophy, alopecia or hypotrichosis, saddle nose deformity, and palmoplantar hyperkeratosis are usually associated with a lack of sweat glands as well [ncbi.nlm.nih.gov]

RESULTS: The clinical and radiological evaluations determined, hypodontia or oligodontia, breathing problems, sweating problems, a history of fever, sparse hair, saddle nose [ncbi.nlm.nih.gov]

Clinical features • It is characterised by hypotrichosis, hypohydrosis and anhidrosis with saddle nose appearance • the hair and scalp and eyebrows tend to be fine, scanty [slideshare.net]

Laryngeal Syphilis

Congenital syphilis occurs in newborn infant who have teeth abnormalities, deafness, misshapen bones, deformed saddle nose, pneumonia, and intellectual disability. [afairgo.net]

Saddle nose Rhagades around the mouth, nostril and anus. Diagnosis of congenital syphilis By the clinical picture. Serological tests: VDRL ,TPI and FTA-ABS (IgM). [drmhijazy.com]

[…] syphilis are Hutchinson's incisors, interstitial keratitis, 8 th nerve deafness, anterior bowing of mid portion of tibia (sabre shins), forehead prominence, otitis media, saddle [ijaweb.org]

Nasal Septum Ulceration

Saddle nose deformity and septal perforation in granulomatosis with polyangiitis. Clinical Otolaryngology, Vol. 43, Issue. 1, p. 291. [cambridge.org]

The resulting sidewall collapse can create a permanent form of nasal deformity sometimes referred to as “saddle nose,” according to a study published in 2005 in the British [drugaddictiontreatment.com]

nose deformity. 1 Reduction in the sense of smell, nasopharyngeal ulceration and dysphonia have also been described. [nature.com]

Pulmonary Syphilis

Occurs in the untreated infant regardless of early sx’s; results from chronic inflammation of the bone, teeth, and CNS HEENT: Saddle nose frontal bossing (“olympian brow”) [johnsarm.net]

Untreated early syphilis infections results in a high risk of poor pregnancy outcomes, including saddle nose, lower extremity abnormalities, miscarriages, premature births [en.wikipedia.org]

nose notched Hutchinson teeth mulberry molars short maxilla saber shins sensorineural deafness Studies Labs nonspecific serologic testing VDRL (venereal disease research [medbullets.com]

Syphilitic Spinal Paralysis

Saddle nose is when your baby has a flat nose. Hutchinson teeth are teeth that are peg-shaped and far apart from each other. [marchofdimes.org]

For those so-called “syphilitic runts” that survived into childhood, their faces and body would bear the characteristic deformities of the disease: a collapsed “saddle” nose [blogs.discovermagazine.com]

Those symptoms include failure to thrive *, irritability, fever, rash, a nose without a bridge (known as saddle nose), bloody fluid from the nose, and a rash on the palms, [humanillnesses.com]