Saddle Nose: Causes & Reasons

Possible Causes for Saddle Nose

For nasal fracture presenting saddle nose deformity, the nasal septum was fixed with the frontal process of the maxillary bone by Kirschner wire. [ncbi.nlm.nih.gov]

Two challenging problems to be addressed in the posttraumatic nose are the crooked nose and saddle nose deformities. [ttsh.com.sg]

Otherwise, there were no complications such as saddle nose, canthal dystopia, canthal webbing, or nasolacrimal outflow obstruction. [ncbi.nlm.nih.gov]

Relapsing Polychondritis

We describe here a case of sarcoidosis that presented with saddle nose resembling relapsing polychondritis. [ncbi.nlm.nih.gov]

Left ear swelling with erythematous change and saddle nose developed during the course of hospitalization, and an ear biopsy demonstrated severe cartilage necrosis. [ncbi.nlm.nih.gov]

Complications include saddle-nose deformity/joint deformity, vertigo, tinnitus, pulmonary infection, laryngotracheobronchial stricture, scleritis or iritis, epiglottitis, [visualdx.com]

Granulomatosis with Polyangiitis

Saddle nose reconstruction in GPA patients with minimal or no local disease is a safe procedure despite an increased rate of revision surgery. [ncbi.nlm.nih.gov]

nose deformity and 20-kilogram unintentional weight loss. [ncbi.nlm.nih.gov]

nose deformity) are the most common chief complaints! [amboss.com]

Rothmund-Thomson Syndrome

Roth·mund syn·drome ( rot'mūnd ), atrophy, pigmentation, and telangiectasia of the skin, usually with juvenile cataract, saddle nose, congenital bone defects, disturbance [medical-dictionary.thefreedictionary.com]

nose, congenital bone defects, disturbances in the growth of HAIR; NAILS; and TEETH; and HYPOGONADISM. [profiles.ucdenver.edu]

Synopsis hereditary dermatosis atrophy pigmentation telangiectasia juvenile cataract saddle nose congenital bone defects disturbances of hair growth hypogonadism. growth deficiency [humpath.com]

CINCA Syndrome

nose. [ncbi.nlm.nih.gov]

Typical facial features include frontal bossing and saddle back nose. [orpha.net]

From the first days of life, patients display an urticarial rash in association with chronic inflammation with a typical facies featured by frontal bossing and saddle back [ncbi.nlm.nih.gov]

Tertiary Syphilis

Nasal deformity, in the form of depression of nose, gradually worsened and developed into a saddle, associated with redness over nose and surrounding area. [peertechz.com]

Ulcers in these areas may cause destruction of the bony and cartilaginous structures (saddle nose) or perforations that sometimes persist despite treatment. [clinicaladvisor.com]

Later manifestations of congenital syphilis include bone and teeth deformities, such as “saddle nose” (due to destruction of the nasal septum), “saber shins” (due to inflammation [emedicine.medscape.com]

Congenital Syphilis

Untreated early syphilis infections results in a high risk of poor pregnancy outcomes, including saddle nose, lower extremity abnormalities, miscarriages, premature births [en.wikipedia.org]

nose and scars at the angles of the mouth. [medical-dictionary.thefreedictionary.com]

nose Perioral fissures Diagnosis : VDRL FTA-ABS Treatment : Penicillin G See Also : Syhilis Torches infections [medlibes.com]

Laron Syndrome

They had typical appearance features of Laron syndrome such as short stature and obesity, with protruding forehead, saddle nose, large eyes, sparse and thin silky hair and [ncbi.nlm.nih.gov]

Facial changes, including protrusion of the forehead, a saddle nose, hypoplasia of the mandible and other facial bones, thin hair and delayed teething are common features [symptoma.com]

Upon examination she was noted to have protruded forehead, thin hair, small hands and feet, and a saddle nose. [alliedacademies.org]

Syphilis

[…] triad A50.54 Late congenital cardiovascular syphilis A50.55 Late congenital syphilitic arthropathy A50.56 Late congenital syphilitic osteochondropathy A50.57 Syphilitic saddle [icd10data.com]

nose A50.59 Other late congenital syphilis, symptomatic A50.6 Late congenital syphilis, latent A50.7 Late congenital syphilis, unspecified A50.9 Congenital syphilis, unspecified [icd10data.com]

Spondyloepimetaphyseal Dysplasia Type SPONASTRIME

nose, frontal bossing, and relatively large head. [ncbi.nlm.nih.gov]

[…] sponastrime dysplasia: familial short-limb dwarfism with saddle nose, spine alterations and metaphyseal striation Helv Paediatr Acta 1983 [semanticscholar.org]

Sponastrime dysplasia is a rare skeletal dysplasia characterized by severe short stature, scoliosis, a saddle nose, frontal bossing, and increased upper/lower segment ratio [ncbi.nlm.nih.gov]

Late Congenital Syphilis

The saddle nose deformity was due to the failure of development of nasal bones. [ijstd.org]

Clinical examination showed the "saddle-nose" deformity, Hutchinson's teeth, high-arched palate, Dubois little-finger sign, and small maxillae resulting in shallow depression [ncbi.nlm.nih.gov]

Occurs in the untreated infant regardless of early sx’s; results from chronic inflammation of the bone, teeth, and CNS HEENT: Saddle nose frontal bossing (“olympian brow”) [johnsarm.net]

Leprosy

BACKGROUND: Facial deformation as a sequela of leprosy is caused not only by a saddle nose but also by regression of the maxilla, as well documented in paleopathological observations [ncbi.nlm.nih.gov]

[…] mixed peripheral neuropathy (often with resultant injuries) +/- hypoesthesia/paresthesia +/- neuralgia peripheral nerve thickening, which may be palpable corneal ulcers saddle-nose [radiopaedia.org]

The bone involvement may also lead to gross deformation of the nose skeleton and ensuing creation of a saddle-nose deformity. [news-medical.net]

Axenfeld-Rieger Syndrome Type 3

[…] deformity Saddle nose Ski jump nose [ more ] 0011120 Cryptorchidism Undescended testes Undescended testis [ more ] 0000028 Ectopia pupillae Displaced pupil 0009918 Growth [rarediseases.info.nih.gov]

[…] chambers [ more ] 0001631 Autosomal dominant inheritance 0000006 Blindness 0000618 Cerebellar vermis hypoplasia 0001320 Concave nasal ridge Boxer's nasal deformity Boxer's nose [rarediseases.info.nih.gov]

Nose Surgery

Repeated violent blows on the organ cause a saddle nose to develop. [beauty-pro.org]

Rhinoplasty can be used to alter or improve the following: Saddle nose Oversized nose Crooked tip Crooked nasal base Drooping tip Hump Bulbous tip Rhinoplasty Consultation [buckinghamfacialplastics.com]

Accidents and direct traumas can also change the shape, the classic example would be the boxer’s nose. [beauty-pro.org]

Lethal Midline Granuloma

Saddle-nose deformity and cauliflower ear are frequent complications. Laryngeal involvement is rare. [headnecksurgery.wordpress.com]

Hunermann-Conradi Syndrome

The disorder recognized by Hünermann also included micromelia, a saddle nose deformity, flexion contractures, cataracts, and a dermopathy. [mhmedical.com]

The severe form is characterised by marked congenital rhizomelic dwarfism, flexion contractures of large joints, small chest and saddle nose deformity. [ijri.org]

Systemic features of chondrodysplasia punctata include stippling of the epiphyses, shortening of the femur and humerus, congenital cataracts, and saddle nose. [accesspediatrics.mhmedical.com]

Mucopolysaccharidosis

Mucopolysaccharidoses (MPS) are lysosomal storage disorders caused by the deficiency of enzymes needed for the stepwise breakdown of glycosaminoglycans (also known as mucopolysaccharides). During the last decades the enzyme deficiencies underlying each disease – as well as the molecular defects causing them –[…] [news-medical.net]

Perforated Nasal Septum

SEPTAL PERFORATION AND SADDLE NOSE DEFORMITY / NASAL DEFORMITY Large septal perforations may cause structural compromise of the nose (deviation of the septum, saddle nose [perforatedseptum.com]

There are various grading systems to saddle nose deformity. However the majority can be corrected in a one-stage procedure as a day case patient. [nosereconstruction.co.uk]

If the perforation is very large, the structure of the nose can become unstable and the tip of the nose can droop, this is called a “saddle nose.” [masseyeandear.org]

Mucopolysaccharidosis Type 2

Abstract The lysosomal storage disorder mucopolysaccharidosis type II (MPS II) is caused by a deficiency in the activity of the lysosomal exohydrolase iduronate-2-sulphatase (IDS). MPS II patients present within a spectrum of clinical phenotypes, which reflects the dynamic balance between the level of mutant protein,[…] [ncbi.nlm.nih.gov]

Moebius Syndrome

OtherPEDIATRICS American Journal of Neuroradiology February 2005, 26 (2) 430-432; Abstract Summary: We describe a case of Möbius syndrome in a 3-month-old infant. Striking imaging findings of pontine hypoplasia in the region of the 6th and the 7th nerve complexes were noted. In addition, absence of the middle[…] [ajnr.org]

Deviated Nasal Septum

The overall incidence of complications was septal perforation in 10 cases (5%), adhesions in 14 cases (7%), recurrence of symptoms or deformity in 12 cases (6%), saddle nose [ncbi.nlm.nih.gov]

congenital Excludes 1: dentofacial anomalies [including malocclusion] (M26.-) syphilitic saddle nose (A50.5) [aapc.com]

Risk factors for intraoperative saddle nose deformity in septoplasty patients. [verywellhealth.com]

Congenital Malformation

Abstract Present methods of prenatal diagnosis are not applicable until at least 16 weeks of gestation. Most abortions for suspected congenital abnormality are therefore usually done in the second trimester of pregnancy. Abortions at over 20 weeks of gestation account for about 0.8% of all abortions for[…] [ncbi.nlm.nih.gov]

Oculocerebrorenal Syndrome

Brian T. Fowler, MD, Shawn Philip, Alpa S. Patel, M.D., Derek W DelMonte, MD, Allison R. Loh, MD, Stephen C. Dryden, M.D., Brandon Baartman, MD Assigned status Update Pending by Derek W DelMonte, MD on March 30, 2022. Disease Entity Disease Lowe syndrome or oculocerebrorenal syndrome of Lowe (OCRL) is a rare disorder[…] [eyewiki.aao.org]

Mucocutaneous Leishmaniasis

Midline destructive lesions have multiple possible etiologies, which can be grouped into neoplastic, infectious, or vasculitis-associated. The purpose of these case reports and literature review was to highlight the need to include mucocutaneous leishmaniasis in the diagnosis of midfacial lesions in any patient who has[…] [ncbi.nlm.nih.gov]

Chondritis of the External Ear

The nose is often afflicted as well and can deteriorate into a flattened nose bridge called saddle nose. [medical-dictionary.thefreedictionary.com]

Nose cartilage involvement/saddle nose Granulomatosis with polyangiitis, leishmaniasis, congenital syphilis, leprosy aspergillosis, paracoccidioidomycosis, Cocaine inhalation [en.wikipedia.org]

nose鞍鼻 salivary gland 唾液腺 salivation唾液分泌 semicircular canal 半規管 senile deafness老人性難聴 sensorineural hearing loss 感音難聴 sensory organ感覚器 sialoadenitis唾液腺炎 sinobronchial syndrome [tokyo-med.ac.jp]

Ectodermal Dysplasia

Appearances of nail dystrophy, alopecia or hypotrichosis, saddle nose deformity, and palmoplantar hyperkeratosis are usually associated with a lack of sweat glands as well [ncbi.nlm.nih.gov]

RESULTS: The clinical and radiological evaluations determined, hypodontia or oligodontia, breathing problems, sweating problems, a history of fever, sparse hair, saddle nose [ncbi.nlm.nih.gov]

Clinical features • It is characterised by hypotrichosis, hypohydrosis and anhidrosis with saddle nose appearance • the hair and scalp and eyebrows tend to be fine, scanty [slideshare.net]

Laryngeal Syphilis

Congenital syphilis occurs in newborn infant who have teeth abnormalities, deafness, misshapen bones, deformed saddle nose, pneumonia, and intellectual disability. [afairgo.net]

Saddle nose Rhagades around the mouth, nostril and anus. Diagnosis of congenital syphilis By the clinical picture. Serological tests: VDRL ,TPI and FTA-ABS (IgM). [drmhijazy.com]

[…] syphilis are Hutchinson's incisors, interstitial keratitis, 8 th nerve deafness, anterior bowing of mid portion of tibia (sabre shins), forehead prominence, otitis media, saddle [ijaweb.org]

Pulmonary Syphilis

Occurs in the untreated infant regardless of early sx’s; results from chronic inflammation of the bone, teeth, and CNS HEENT: Saddle nose frontal bossing (“olympian brow”) [johnsarm.net]

Untreated early syphilis infections results in a high risk of poor pregnancy outcomes, including saddle nose, lower extremity abnormalities, miscarriages, premature births [en.wikipedia.org]

nose notched Hutchinson teeth mulberry molars short maxilla saber shins sensorineural deafness Studies Labs nonspecific serologic testing VDRL (venereal disease research [medbullets.com]

Mowat-Wilson Syndrome

nose with prominent rounded nasal tip, prominent columella, open mouth, with M-shaped upper lip, frequent smiling, and a prominent but narrow and triangular pointed chin) [ncbi.nlm.nih.gov]

nose with prominent rounded nasal tip, prominent columella, open mouth with M-shaped upper lip, and a prominent but narrow and triangular pointed chin. [orpha.net]

large eyebrows that are medially flaring and sparse in the middle part, hypertelorism, deep set but large eyes, large and uplifted ear lobes with a central depression, saddle [orpha.net]

Hutchinson's Teeth

[…] triad A50.54 Late congenital cardiovascular syphilis A50.55 Late congenital syphilitic arthropathy A50.56 Late congenital syphilitic osteochondropathy A50.57 Syphilitic saddle [healthprovidersdata.com]

Newborns tend not to show any symptoms, but older children may develop deafness, saddle nose or teeth abnormalities. [colgate.com]

The most important signs are frontal bossae (bony prominences of the forehead) (87%), saddle nose (74%), short maxilla (83%), high arched palate (76%), mulberry molars (more [dartmouth.edu]