Scleral Icterus: Causes & Reasons

Possible Causes for Scleral Icterus

[…] of urine and scleral icterus precede yellowing of skin Other causes of yellow skin carotenemia. carotenemia does not cause scleral icterus Hyperbilirubinemia per se has no [meddean.luc.edu]

Definition Jaundice: yellowish discoloration of the skin, sclerae, and mucous membranes due to the deposition of bilirubin Scleral icterus: discoloration of the whites of [amboss.com]

icterus is unacceptable to a patient et Võimaldamaks tõhusat ja ametlikku järelevalvet artikli # lõikes # osutatud sööda üle, rakendatakse järgmisi sätteid en It should not [et.glosbe.com]

Cholestasis

Her physical exam was remarkable for jaundice and scleral icterus without any stigmata of liver disease. [ncbi.nlm.nih.gov]

It results in jaundice, which can be detected by scleral icterus at a concentration as low as 2 mg/dL, and by dark urine. [emedicine.medscape.com]

Ascending Cholangitis

Initial Presentation: Jaundice Abdominal pain Fever Vital Signs: Fever can be present given this is an infectious process Dermatological Exam: Scleral icterus Jaundice Abdominal [stepwards.com]

She has scleral icterus and jaundice (worsened per family). The patient grimaces on palpation of the right upper quadrant. [emdocs.net]

It results in jaundice, which can be detected by scleral icterus at a concentration as low as 2 mg/dL, and by dark urine. [emedicine.medscape.com]

Toxic Hemolytic Anemia

Scleral icterus and/or jaundice may occur, and the spleen may enlarge. [merckmanuals.com]

Also check for jaundice, or scleral icterus. Cervical, axillary and inguinal lymphadenopathy may be present. [clinicaladvisor.com]

Extrahepatic Cholestasis

Definition Jaundice : yellowish discoloration of the skin, sclerae, and mucous membranes due to the deposition of bilirubin Scleral icterus : discoloration of the sclerae, [amboss.com]

Icterus - cutaneous jaundice is usually seen at serum concentrations of about 85.5 μmol/L but scleral icterus can be seen at concentrations as low as 34.2 μmol/L. [patient.info]

It results in jaundice, which can be detected by scleral icterus at a concentration as low as 2 mg/dL, and by dark urine. [emedicine.medscape.com]

Choledocholithiasis

Scleral icterus may be present, but is not a reliable sign. In case of cholangitis, fever, tachycardia and hypotension may be present. [hepatitis.va.gov]

icterus Caused by buildup of direct bilirubin in blood Differential Diagnosis RUQ Pain Gallbladder disease Acute cholecystitis Cholangitis Symptomatic cholelithiasis/Biliary [wikem.org]

She has slight scleral icterus. She has noted dark- coloured urine. [slideshare.net]

Drug-Induced Cholestatic Hepatitis

His pertinent physical exam findings were scleral icterus and jaundice all over the body and evidence of scratch marks and excoriations from itching but no abdominal distention [karger.com]

Physical examination was unremarkable other than mild scleral icterus. No hepatosplenomegaly or other stigmata of chronic liver disease was apparent. [gastroenterologyandhepatology.net]

Isoniazid Hepatitis

icterus, or “hepatitis” notation 5300 15 (0.37%) b 1 (.019%) Nolan 6 Jan. 1989 to 1 December 1995 Monthly symptom-based screening AST >5x normal with symptoms, and no other [mdedge.com]

IUATCP 4 mid-1970s Every-4-week symptom-based screening Not defined 20,840 95 (0.5%) 3 (0.014%) Dash 4 Jan. 1973 to June 1977 Monthly symptom based screening Jaundice, scleral [mdedge.com]

Hepatic Sarcoidosis

Physical exam revealed scleral icterus, generalized lymphadenopathy, and tender hepatosplenomegaly. [acgcasereports.gi.org]

Physical examination found scleral icterus but was otherwise unremarkable. [acgcasereports.gi.org]

Drug-Induced Toxic Hepatitis

Patient 1 On July 16, 1992, a 42-year-old man visited his family physician for evaluation of scleral icterus and diffuse jaundice. [cdc.gov]

Autoimmune Hemolytic Anemia

Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale. [ncbi.nlm.nih.gov]

His physical examination was remarkable for scleral icterus, shifting dullness, hepatosplenomegaly and bilateral lower-extremity pitting edema. [dx.doi.org]

Toxic Hepatitis

A 47-year-old woman was admitted to our clinic with weakness, fatigue, pruritus, and scleral icterus that had developed 10 days prior to presentation. [ncbi.nlm.nih.gov]

Patient 1 On July 16, 1992, a 42-year-old man visited his family physician for evaluation of scleral icterus and diffuse jaundice. [cdc.gov]

Rotor Syndrome

Some patients only have scleral icterus. Patients will also complain about passing dark-colored urine. [statpearls.com]

Some patients only have scleral icterus. Patients also complain about passing dark-colored urine, long-term jaundice, and fatigue. [ncbi.nlm.nih.gov]

Unlike true jaundice, carotenemia does not result in scleral icterus or elevation of the bilirubin level. 8 PREHEPATIC CAUSES Unconjugated hyperbilirubinemia results from [aafp.org]

Secondary Sclerosing Cholangitis

A 55-year-old morbidly obese male presented electively with a 2-week history of low back pain and scleral icterus for 2 days. [karger.com]

Giant Cell Hepatitis

CLINICAL PRESENTATIONCLINICAL PRESENTATION Jaundice Scleral icterus Hepatomegaly Acholic stools Dark urine Other signs and symptoms depend on specific disease process [slideshare.net]

At 30 hours of life, the infant was noted to have scleral icterus. [nature.com]

Progressive Familial Intrahepatic Cholestasis

History The following may be noted in the history of a patient with progressive familial intrahepatic cholestasis (PFIC) Jaundice Scleral icterus Cutaneous jaundice Dark urine [emedicine.medscape.com]

Physical See the list below: Pruritus Scratching Cutaneous mutilation Irritability in infants Jaundice Scleral icterus Cutaneous jaundice Hepatomegaly Splenomegaly Altered [emedicine.medscape.com]

Chronic Active Hepatitis B

Physical examination is remarkable for right upper quadrant tenderness, generalized jaundice, and scleral icterus. [medbullets.com]

Presentation Symptoms acute hepatitis anorexia nausea right upper quadrant pain chronic hepatitis many are asymptomatic fatigue Physical exam acute hepatitis jaundice and scleral [medbullets.com]

icterus typically resolves in 1-3 months chronic hepatitis normal may have stigmata of chronic liver disease e.g., spider angiomata, ascites, and asterixis extrahepatic manifestations [medbullets.com]

Portal Cirrhosis

icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis [aafp.org]

icterus Yellow discoloration of skin, cornea, and mucous membranes Increasing serum bilirubin due to compromised hepatocyte excretory function Spider angiomata Central arteriole [pathophys.org]

Scleral icterus can usually be detected if the serum bilirubin level is greater than 3.0 mg/dL. [hepatitisc.uw.edu]

Liver Cirrhosis

In the presented case, the authors describe an obese middle-aged man that presented to the emergency department for persistent oedema, scleral icterus and fatigue. [ncbi.nlm.nih.gov]

A compelling clinical picture required, in the absence of other explanations, the presence of at least 4 of the following: spider nevi, scleral icterus, palmar erythema, ascites [archinte.ama-assn.org]

Viral Hepatitis

Physical exam Assessment of the patient may yield remarkable findings such as jaundice, scleral icterus, and an enlarged and tender liver. [symptoma.com]

Icteric Phase During this phase clinical signs of jaundice and scleral icterus will appear and some right upper quadrant tenderness may develop due to enlargement of the liver [pathwaymedicine.org]

This is sometimes referred to as scleral icterus. [en.wikipedia.org]

Intrahepatic Cholestasis

Scleral icterus and jaundice were observed at 27 weeks. [ncbi.nlm.nih.gov]

Macronodular Cirrhosis

icterus BREATH: Fetor hepaticus (musty odor of breath and urine found in cirrhosis with hepatic failure) CHEST: Possible gynecomastia in men ABDOMEN: Tender hepatomegaly [encyclopedia.lubopitko-bg.com]

[…] cirrhosis), needle tracks (viral hepatitis) EYES: Kayser-Fleischer rings (corneal copper deposition seen in Wilson’s disease; best diagnosed with slit lamp examination), scleral [encyclopedia.lubopitko-bg.com]

Alcoholic Hepatitis

Physical Exam: VS: T 98.9 HR 104 RR 19 BP 117/67 O2 99% RA Gen: Well-appearing obese female in no acute distress HEENT: PERRL, marked scleral icterus, sublingual icterus, [ddxof.com]

icterus, skin and sublingual jaundice). [clinicaladvisor.com]

Emergent endoscopy Sigmoidoscopy/colonoscopy Vitamin K 5mg PO daily for 3 days (will treat concomitant nutritional deficiency of vitamin K) Evaluate for jaundice (evaluate for scleral [clinicaladvisor.com]

Crigler-Najjar Syndrome Type 1

On preoperative examination, the patient was awake and alert and had no stigmata of hyperbilirubinemia, except for mild scleral icterus. [journals.lww.com]

Secondary Biliary Cirrhosis

icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis [aafp.org]

icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy Most patients with cirrhosis severe enough to lead to ascites have additional [aafp.org]

[…] nails—paired horizontal white bands separated by normal color Terry’s nails—proximal two thirds of nail plate appears white, whereas the distal one third is red Palmar erythema Scleral [aafp.org]

Polycythemia Neonatorum

The most notable signs of hyperbilirubinemia are jaundice and scleral icterus. [pathophys.org]

Roughly, the following serum levels have been observed to correlate with clinical findings: 34-51 umol/L – scleral icterus 68-86 umol/L – jaundice on face 258 umol/L – jaundice [pathophys.org]

Liver Failure

icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis [aafp.org]

Jaundice (yellowing of the skin) and scleral icterus (yellowing of the eyes) are often present, but may not be initially noted by patients or their families until relatively [surgery.ucsf.edu]

icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy Most patients with cirrhosis severe enough to lead to ascites have additional [aafp.org]

Bile Duct Stricture

Mild jaundice and mild scleral icterus were present. [acgcasereports.gi.org]

Gilbert Syndrome

Icterus Morphine Glucuronide These keywords were added by machine and not by the authors. [link.springer.com]

[…] that the defect responsible for the inadequate bilirubin conjugation which is characteristic of Gilbert's Disease may also Keywords Morphine Morphine Sulfate Cephaloridine Scleral [link.springer.com]

Acute Cholecystitis

The presence of scleral icterus or frank jaundice makes the diagnosis of acute cholecystitis unlikely. [clinicaladvisor.com]

It results in jaundice, which can be detected by scleral icterus at a concentration as low as 2 mg/dL, and by dark urine. [emedicine.medscape.com]