Sclerocornea & Spontaneous Rupture of Membranes & Tricuspid Valve Insufficiency: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Sclerocornea, Spontaneous Rupture of Membranes, Tricuspid Valve Insufficiency,

Negated

None

Unsure

None

Possible Causes

Brittle Cornea Syndrome Type 2

Valve Insufficiency Ebstein Anomaly NEXN Nexilin Dilated Cardiomyopathy 1CC (CMD1CC) Familial Hypertrophic Cardiomyopathy Type 20 NF1 Neurofibromin 1 Congenital Heart Diseases [bcm.edu]

Problems during delivery Due to the fragility of connective tissue, those with EDS are more prone to prelabour spontaneous rupture of membranes (SROM), including preterm SROM [patient.info]

[…] cornea ; Gait disturbance ; Hearing impairment ; Inguinal hernia ; Joint hypermobility ; Keratoconus ; Keratoglobus ; Megalocornea ; Myalgia ; Myopia ; Recurrent fractures ; Sclerocornea [mousephenotype.org]

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Ehlers-Danlos Syndrome

valve insufficiency often complicating with "true" mitral valve prolapse in the ecocardiographic study. [ncbi.nlm.nih.gov]

Problems during delivery Due to the fragility of connective tissue, those with EDS are more prone to prelabour spontaneous rupture of membranes (SROM), including preterm SROM [patient.info]

membranes and tissues. [rarediseases.org]

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Mitral Valve Insufficiency

[…] prolapse）狭窄主动脉瓣（英语：aortic valve）狭窄 insufficiency（英语：Aortic insufficiency）三尖瓣狭窄（英语：Tricuspid valve stenosis） insufficiency（英语：Tricuspid insufficiency） pulmonary（英语：pulmonary [zh.wikipedia.org]

[…] of membranes. [ncbi.nlm.nih.gov]

Rheumatic tricuspid insufficiency. [aapc.com]

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Isolated Congenital Sclerocornea

Acute ruptures of Descemet membrane or acute hydrops may occur, leading to corneal edema that often resolves spontaneously, leaving stromal scarring. [doctorlib.info]

Homepage Rare diseases Search Search for a rare disease Isolated congenital sclerocornea ORPHA:91490 Synonym(s): - Prevalence: - Inheritance: - Age of onset: - ICD-10: Q13.3 [orpha.net]

The extent of the resulting opacity varies from peripheral to total (sclerocornea totalis). [en.wikipedia.org]

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Familial Congenital Nasolacrimal Duct Obstruction

Tricuspid, aortic, and mitral insufficiency have also been reported. [medicalhomeportal.org]

rupture of membranes (1) Thyroid disease in pregnancy (1) Transdermal contraception (1) Vaginal birth after cesarean (1) Vaginal bleeding (1) Vaginal smears (17) Hematologic [innovations.ahrq.gov]

Congenital glaucoma, nystagmus, cataracts, lacrimal duct obstruction (37%), ptosis (29%), colobomas and numerous corneal abnormalities including keratoglobus, sclerocornea [disorders.eyes.arizona.edu]

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Congenital Heart Disease

Tricuspid (systemic) valve insufficiency is often also an important component in the development of heart failure. [doi.org]

Approximately 17% to 21% of all patients with CHD ultimately deliver preterm as a result of either spontaneous preterm labor/preterm premature rupture of membranes (59%) or [doi.org]

Valvular dysfunction Insufficiency of the tricuspid valve, which is located on the systemic ventricle, can appear after surgical atrial correction, but it is infrequent in [revespcardiol.org]

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Congenital Primary Aphakia

Unfortunately, these cases often develop glaucoma, and the natural history is that when untreated, they will often spontaneously rupture. 38 This author tried to place an [journals.lww.com]

Conclusions: : Two novel families with the sclerocornea-aphakia complex due to FOXe3 mutations are presented. [iovs.arvojournals.org]

In some cases, CPA can be associated with other eye abnormalities including microphthalmia, absence of the iris, anterior segment aplasia, and/or sclerocornea (when the cornea [checkorphan.org]

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Heart Failure

Secondary changes in valve function, particularly the severity of mitral and tricuspid valve insufficiency, should be determined. [doi.org]

Secondary changes, particularly the severity of mitral and tricuspid valve insufficiency, should be determined. [doi.org]

All valves should be evaluated for anatomic and flow abnormalities to exclude the presence of primary valve disease. [doi.org]

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Congestive Heart Failure

Secondary changes in valve function, particularly the severity of mitral and tricuspid valve insufficiency, should be determined. [doi.org]

Secondary changes, particularly the severity of mitral and tricuspid valve insufficiency, should be determined. [doi.org]

All valves should be evaluated for anatomic and flow abnormalities to exclude the presence of primary valve disease. [doi.org]

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Syndromic Microphthalmia Type 10

Valve Insufficiency Ebstein Anomaly NEXN Nexilin Dilated Cardiomyopathy 1CC (CMD1CC) Familial Hypertrophic Cardiomyopathy Type 20 NF1 Neurofibromin 1 Congenital Heart Diseases [bcm.edu]

Ophthalmologic evaluation revealed right microphthalmia, aniridia and sclerocornea. Physical examination was otherwise normal. [medicaljournals.se]

[…] disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Iris coloboma Cat eye 0000612 Patent ductus arteriosus 0001643 Sclerocornea [rarediseases.info.nih.gov]

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Keratoglobus

Spontaneous rupture/tear of Descemet's membrane Acute hydrops Scarring or neovascularization of the stroma Symptoms Decreased visual acuity Suboptimal visual acuity with [eyewiki.aao.org]

Keywords: Megalocornea, keratoglobus, keratoconus, cystinosis, mucopolysaccharidosis, sclerocornea, Peters' anomaly, familial dysautonomia, corneal dystrophy DOI: 10.3233/ [content.iospress.com]

Abnormalities) Cornea plana Cornea Plana Corneal (Limbal) Dermoid Keratoglobus Keratoglobus Keratoglobus Keratoglobus Keratoglobus Megalocornea Peters' Anomaly Posterior Keratoconus Sclerocornea [atlasophthalmology.net]

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Cardiomyopathy

Cardiomyopathy is disease in which the heart muscle becomes weakened, stretched, or has another structural problem. It often occurs when the heart cannot pump or function well. Most people with cardiomyopathy have heart failure. There are many types of cardiomyopathy, with different causes. Some of the more[…] [nlm.nih.gov]

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Coronary Atherosclerosis

Coronary artery disease (CAD) exhibits the rules of the multifactorial hereditary. Notwithstanding, the role of genetic factors in the prevalence of CAD is estimated very high. SIRT1 plays an athero-protective role and alterations in its expression have some important consequence in the metabolism, cholesterol, and[…] [ncbi.nlm.nih.gov]

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Myocardial Infarction

Lightning strike is an infrequent natural phenomenon with serious medical complications, like multiple organ damage, and it is associated with increased risk of mortality. Cardiovascular complications are among the most hazardous complications of lightning strike. Lightning strike can cause various serious consequences[…] [ncbi.nlm.nih.gov]

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Acute Myocardial Infarction

We herein report the case of a 25-year-old Japanese woman with left-main-trunk acute myocardial infarction (LMT-AMI). She had cardiogenic shock, so emergency percutaneous intervention was performed. Intravascular ultrasound of LMT-AMI showed that the three-layered structure of the intima, tunica media, and[…] [ncbi.nlm.nih.gov]

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Malignant Neoplasm of the Lung

A primary or metastatic malignant neoplasm involving the lung. [from NCI ] Etiology Eur J Cardiothorac Surg 2017 Dec 1;52(6):1041-1048. doi: 10.1093/ejcts/ezx272. PMID: 28950348 Behr J, Bendstrup E, Crestani B, Günther A, Olschewski H, Sköld CM, Wells A, Wuyts W, Koschel D, Kreuter M, Wallaert B, Lin CY, Beck J, Albera C[…] [ncbi.nlm.nih.gov]

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Cor Pulmonale

Cor pulmonale is defined as an alteration in the structure and function of the right ventricle of the heart as a response to a disorder of the respiratory system. The chronic form usually leads to right ventricular hypertrophy, the acute form results in dilatation. The symptoms of cor pulmonale, pulmonary heart[…] [symptoma.com]

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Spontaneous Rupture of Membranes

We conclude that there is no advantage to delaying induction of labor when women present at term with spontaneous rupture of membranes. [ncbi.nlm.nih.gov]

CONCLUSIONS: There is a 24 h rhythm in the timing of spontaneous rupture of membranes in term gestations. [ncbi.nlm.nih.gov]

Early spontaneous rupture of membranes initiated preterm labor, and a cesarean section was performed at 36 weeks' gestation because of fetal distress. [acronymfinder.com]

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Ring Dermoid of Cornea

Acute spontaneous breaks in Descemet’s membrane may produce focal stromal edema (acute hydrops) and heal spontaneously in weeks to months ( Fig. 10.8B ). [entokey.com]

This infant has bilateral glaucoma, Peters’ anomaly type II, and features of sclerocornea. Fig. 4-3-8 Peters’ anomaly. [slideshare.net]

Sclerocornea and Anomalies of Size Clinically, sclerocornea is a rare, bilateral clouding of the cornea. [reviewofcontactlenses.com]

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Infective Endocarditis

Tricuspid regurgitation: the backflow of blood from the right ventricle into the right atrium, owing to imperfect functioning (insufficiency) of the tricuspid valve. [en.wikipedia.org]

tricuspid insufficiency that required correction of the DeVega annuloplasty type, but no signs of infective endocarditis were observed in that valve. [scielo.br]

Pulmonic regurgitation: the backflow of blood from the pulmonary artery into the right ventricle, owing to insufficiency of the pulmonic semilunar valve. [en.wikipedia.org]

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Chronic Right-Sided Congestive Heart Failure

Home CCC Right Ventricular Failure by, last update March 24, 2019 Reviewed and revised 26 June 2014 OVERVIEW mortality as high as LV failure RV is better suited to volume overload than left due to compliance and thin wall but when PVR increases for whatever reason - RV dilates when the dilation maximised - reversal[…] [lifeinthefastlane.com]

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Tricuspid Valve Insufficiency

Tricuspid valve insufficiency may be asymptomatic in patients with moderate, or even severe, stage of the disease. [symptoma.com]

Seven days later the clinical signs of tricuspid valve insufficiency and concomitant right heart failure had disappeared. [ncbi.nlm.nih.gov]

Definition Tricuspid valve insufficiency occurs when a tricuspid valve does not close tightly enough to prevent leakage. [medical-dictionary.thefreedictionary.com]

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Right-Sided Bacterial Endocarditis

Key words Infective endocarditis Tricuspid insufficiency Tricuspid valve replacement Tricuspid repair This is a preview of subscription content, log in to check access. [link.springer.com]

The initial moderate insufficiency after tricuspid repair is well tolerated by the patients, and valvular competence generally improves over time ( 4 ). [ispub.com]

Moderate tricuspid insufficiency ( 41 ]. [academic.oup.com]

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Pulmonary Hypertension

[…] component (P 2 ) Anginal chest pain Right-sided third heart sound (S 3 ) Hemoptysis Tricuspid insufficiency murmur Raynaud's phenomenon Hepatomegaly Peripheral edema TABLE [aafp.org]

[…] component (P 2 ) Anginal chest pain Right-sided third heart sound (S 3 ) Hemoptysis Tricuspid insufficiency murmur Raynaud's phenomenon Hepatomegaly Peripheral edema Hemoptysis [aafp.org]

Symptoms and Signs of Pulmonary Hypertension Symptoms Signs Dyspnea on exertion Jugular vein distention Fatigue Prominent right ventricular impulse Syncope Accentuated pulmonic valve [aafp.org]

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Tricuspid Stenosis

tricuspid (valve) incompetence Nonrheumatic tricuspid (valve) regurgitation I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency I36.8 Other nonrheumatic tricuspid [icd10coded.com]

insufficiency I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency I36.8 Other nonrheumatic tricuspid valve disorders I36.9 Nonrheumatic tricuspid valve disorder [icd10data.com]

Tricuspid valve insufficiency/regurgitation If you have tricuspid valve insufficiency/regurgitation, your tricuspid valve does not close completely, causing blood to flow [nm.org]

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Adrenal Infarction

[…] through the orifice (valvular regurgitation); named, according to the valve affected, aortic, mitral, pulmonary or tricuspid insufficiency. velopharyngeal insufficiency failure [medical-dictionary.thefreedictionary.com]

At 32 weeks she experienced spontaneous rupture of membranes. One week later she delivered vaginally and remained anticoagulated for the puerperium. [ncbi.nlm.nih.gov]

See also respiratory insufficiency. thyroid insufficiency hypothyroidism. valvular insufficiency failure of a cardiac valve to close perfectly, causing the blood to flow back [medical-dictionary.thefreedictionary.com]

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Bacterial Endocarditis

Tricuspid regurgitation: the backflow of blood from the right ventricle into the right atrium, owing to imperfect functioning (insufficiency) of the tricuspid valve. [en.wikipedia.org]

वाल्व mitral ( regurgitation, prolapse, stenosis )· aortic ( stenosis, insufficiency )· tricuspid ( stenosis, insufficiency )· pulmonary ( stenosis, insufficiency ) mitral [helpebookhindi.wikifoundry.com]

Pulmonic regurgitation: the backflow of blood from the pulmonary artery into the right ventricle, owing to insufficiency of the pulmonic semilunar valve. [en.wikipedia.org]

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Acute Bacterial Endocarditis

[…] and dysfunction (esp. mitral insufficiency) occurring during acute rheumatic fever. right-sided endocarditis Endocarditis affecting the tricuspid or pulmonary valve. [medical-dictionary.thefreedictionary.com]

Synonym: verrucous endocarditis prosthetic valve endocarditis Bacterial infection of a surgically implanted artificial heart valve. rheumatic endocarditis Valvular inflammation [medical-dictionary.thefreedictionary.com]

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Endocarditis

Tricuspid regurgitation: the backflow of blood from the right ventricle into the right atrium, owing to imperfect functioning (insufficiency) of the tricuspid valve. [en.wikipedia.org]

All of these pathologic changes induce valvular insufficiency, mainly involved in aortic valve (50%), mitral valve (40%) and tricuspid valve (6%) [14]. [intechopen.com]

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Pulmonary Valve Insufficiency

Abstract The rare congenital anomaly of pulmonary valve stenosis and massive tricuspid valve insufficiency with intact ventricular septum is a lethal condition without reported [link.springer.com]

Tricuspid regurgitation is also known as tricuspid valve insufficiency. Tricuspid regurgitation may not cause any recognizable symptoms at first. [healthline.com]

tricuspid (valve) insufficiency I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency I36.8 Other nonrheumatic tricuspid valve disorders I36.9 Nonrheumatic tricuspid [icd10data.com]

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