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17 Possible Causes for Scleromalacia Perforans, Severe Clinical Course

  • Scleritis and Episcleritis

    Of these, 13 were regarded as scleromalacia perforans. Posterior scleritis (6 eyes) The diagnosis is based on an exact clinical examination which is fully described.[ncbi.nlm.nih.gov] Clinical Ophthalmology: A Systematic Approach. China: Elsevier Inc, 201# External Disease and Cornea, Section # Basic and Clinical Science Course, AAO, 2010.[eyewiki.aao.org] perforans, and posterior) and episcleritis (simple and nodular).[ncbi.nlm.nih.gov]

  • Episcleritis

    Of these, 13 were regarded as scleromalacia perforans. Posterior scleritis (6 eyes) The diagnosis is based on an exact clinical examination which is fully described.[doi.org] Clinical Ophthalmology: A Systematic Approach. China: Elsevier Inc, 201# External Disease and Cornea, Section # Basic and Clinical Science Course, AAO, 2010.[eyewiki.aao.org] Effect of cortisone on rheumatoid nodules of the sclera (scleromalacia perforans).[ncbi.nlm.nih.gov]

  • Rheumatoid Nodule

    Scleral localization has been designated as scleromalacia perforans, 4 scleritis necroticans, 5 necroscleritis nodosa excavans 6 or nodular episcleritis, 7 depending on the[jamanetwork.com] Clinical Course The course of rheumatoid arthritis cannot be predicted in a given patient.[hopkinsarthritis.org] Therapy consists of stopping the medication; most patients will have clinical improvement within days with radiological improvement over the course of several weeks.[err.ersjournals.com]

  • Disorder of the Globe

    Scleromalacia perforans [ 22 ] There is no specific effective treatment. Topical treatment is insufficient.[patient.info] Generalized anxiety disorder typically begins in adulthood and persists over time, although onset is later and clinical course is more persistent in lower-income countries[hcp.med.harvard.edu] Necrotising scleritis without inflammation (scleromalacia perforans) - (4% of cases of scleritis). This is notable for its lack of symptoms.[patient.info]

  • Pyoderma Gangrenosum

    Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and acute myeloid leukemia. Ophthalmic Surg Lasers. 1998 Apr. 29(4):328-31. [Medline].[emedicine.com] The clinical course may follow two patterns: Explosive onset and rapid spread of lesions, with pain, systemic illness and fever.[patient.info] The clinical course of PPG is not always associated with the severity of its underlying systemic diseases [ 48 ].[gastro.oxfordjournals.org]

  • Pyoderma

    Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and acute myeloid leukemia. Ophthalmic Surg Lasers. 1998 Apr. 29(4):328-31. [Medline].[emedicine.medscape.com] The clinical course may follow two patterns: Explosive onset and rapid spread of lesions, with pain, systemic illness and fever.[patient.info] course may present two patterns: Explosive onset and rapidly progressive Indolent and gradually progressive.[ncbi.nlm.nih.gov]

  • Hereditary Corneal Dystrophy

    Graefes-Arch-Clin-Exp-Ophthalmol. 1998 Apr; 236(4): 291-4 Ayyala,-R-S; Armstrong,-S Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and[malattierare.regione.veneto.it] TBCD has similarities to RBCD, but perhaps has a less severe clinical course; without a tissue examination or molecular genetic analysis TBCD is commonly misdiagnosed as RBCD[ojrd.biomedcentral.com] perforans.[carolinaeyecare.com]

  • Erythropoietic Porphyria

    The patient had normal vision in both eyes with bilateral scleromalacia perforans. The right eye showed painful, nodular scleritis.[ncbi.nlm.nih.gov] Thus, genotype determinations in newly diagnosed infants should be performed to predict the severity of the future clinical course, and in particular, the likelihood of transfusion[bloodjournal.org] To report a case of congenital erythropoietic porphyria that presented as acute scleritis over a bilateral scleromalacia perforans in the interpalpebral fissure.[ncbi.nlm.nih.gov]

  • Reis-Bucklers Corneal Dystrophy

    Graefes-Arch-Clin-Exp-Ophthalmol. 1998 Apr; 236(4): 291-4 Ayyala,-R-S; Armstrong,-S Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and[malattierare.regione.veneto.it] Differential diagnosis RBCD is clinically similar to Thiel-Behnke corneal dystrophy (TBCD, see this term), but generally has a more severe course.[orpha.net]

  • Isolated Congenital Sclerocornea

    A) Diffuse anterior scleritis B) Necrotizing scleritis with inflammation C) Nodular anterior scleritis D) Scleromalacia perforans 136 All of the following have been associated[doctorlib.info] […] of course, be dependent on patient age.[reviewofcontactlenses.com] Ashton N, Hobbs HE: Effect of cortisone on rheumatoid nodules of the sclera (scleromalacia perforans). Br J Ophthalmol 36:373, 1952 PubMed Google Scholar 15.[link.springer.com]

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