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38 Possible Causes for Scleromalacia Perforans, Skin Ulcer

  • Pyoderma Gangrenosum

    Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and acute myeloid leukemia. Ophthalmic Surg Lasers. 1998 Apr. 29(4):328-31. [Medline].[emedicine.com] Ninety-five patients (49 from our institution and 46 described in the literature) had skin ulcers with a clinical resemblance to pyoderma gangrenosum.[ncbi.nlm.nih.gov] Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and acute myeloid leukemia. Ophthalmic Surg Lasers . 1998 Apr. 29(4):328-31.[emedicine.medscape.com]

  • Pyoderma

    Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and acute myeloid leukemia. Ophthalmic Surg Lasers. 1998 Apr. 29(4):328-31. [Medline].[emedicine.medscape.com] Interleukin-8 overexpression is present in pyoderma gangrenosum ulcers and leads to ulcer formation in human skin xenografts. Lab Invest 2000 ;80: 595 - 604 45.[nejm.org] A skin ulcer is an open sore in the skin. Pyoderma gangrenosum is an uncommon form of skin ulcers.[uvahealth.com]

  • Scleromalacia Perforans

    Scleromalacia perforans is a rare ocular manifestation of rheumatoid arthritis which can potentially lead to blindness and is a late consequence in the course of the disease[ncbi.nlm.nih.gov] Pyoderma gangrenosum is a destructive, necrotizing noninfective ulceration of the skin that presents as a furuncle-like nodule, pustule, or hemorrhagic bulla. ' Even though[healio.com] The only systemic disease currently recognized to be complicated by scleromalacia perforans is rheumatoid arthritis.[ncbi.nlm.nih.gov]

  • Episcleritis

    Of these, 13 were regarded as scleromalacia perforans. Posterior scleritis (6 eyes) The diagnosis is based on an exact clinical examination which is fully described.[doi.org] […] atopic keratoconjunctivitis. [1] A review of systems should be completed and if the patient has a history of or is currently is suffering from joint/muscle pain or weakness, skin[statpearls.com] Effect of cortisone on rheumatoid nodules of the sclera (scleromalacia perforans).[ncbi.nlm.nih.gov]

  • Scleromalacia

    Scleromalacia perforans is a form of advanced scleromalacia .[ivyroses.com] Rheumatoid vasculitis can thus commonly present with skin ulceration and vasculitic nerve infarction known as mononeuritis multiplex . [20] Other, rather rare, skin associated[en.wikipedia.org] Treatment of Scleromalacia Perforans The usual treatment of Scleromalacia Perforans includes the use of both the topical and systemic medications.[webeyeclinic.com]

  • Sclerosing Keratitis

    It is often associated with scleromalacia perforans. b. Is corneal graft useful in this patient?[mrcophth.com] Associated with diseases of skin and mucous membrane Associated with systemic collagen vascular disorders Traumatic keratitis Idiopathic keratitis Mooren's Corneal Ulcer[en.wikibooks.org] Skin involvement includes subcutaneous nodules over bony prominences, and vasculitis which may cause ulcerations.[file.scirp.org]

  • Rheumatoid Nodule

    Scleral localization has been designated as scleromalacia perforans, 4 scleritis necroticans, 5 necroscleritis nodosa excavans 6 or nodular episcleritis, 7 depending on the[jamanetwork.com] Skin changes caused by rheumatoid vasculitis include: Skin ulcers (usually leg ulcers ) may be extensive and painful Petechiae (purplish spots) or purpura Nail fold or edge[dermnetnz.org] Added pressure on the toes can cause skin ulcers and calluses. In time, claw toes can become stuck in position and unable to flex inside a shoe.[healthline.com]

  • Erythropoietic Porphyria

    The patient had normal vision in both eyes with bilateral scleromalacia perforans. The right eye showed painful, nodular scleritis.[ncbi.nlm.nih.gov] This causes the skin to become fragile and blister or ulcerate.[porphyria.eu] Skin ulcers need to be kept clean, dressed appropriately and infection treated in order to help healing.[britishskinfoundation.org.uk]

  • Porphyria Cutanea Tarda

    perforans.[nature.com] You may have frequent skin damage from sun and small injuries. This may cause skin ulcers, infections, bleeding, and swelling. You can develop cirrhosis or liver cancer.[drugs.com] Skin ulceration resulting in scarring of the skin Hyperpigmentation Sun-exposed areas of the body are affected the most, such as the face, neck, shoulders, arms (including[dovemed.com]

  • Disorder of the Globe

    Scleromalacia perforans [ 22 ] There is no specific effective treatment. Topical treatment is insufficient.[patient.info] The most usual type, called a basal cell carcinoma (or “rodent ulcer”), starts as a small nodule in the skin that gradually enlarges and breaks down to form an ulcer with[britannica.com] Necrotising scleritis without inflammation (scleromalacia perforans) - (4% of cases of scleritis). This is notable for its lack of symptoms.[patient.info]

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