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76 Possible Causes for Seizure, Temporal Optic Nerve Pallor

  • Septo-Optic Dysplasia

    A 7-year-old boy was admitted for a general tonic-clonic seizure with severe hypoglycaemia (1.39 mmol/l).[] A four-year-old female presented with monocular nystagmus and temporal optic disc pallor in her left eye.[] A female infant presented with poor feeding, hypotonia, prolonged jaundice, seizure and wandering nystagmus.[]

  • Brain Compression

    Seizures often occur at the time the hematoma forms, or up to months or years after treatment. But medicines can help control the seizures.[] 1) Figure 1 : Color fundus photographs, revealing temporal optic nerve pallor OU.[] Continued anti-seizure treatments are used only if seizures occur. Coma-inducing drugs.[]

  • Meningitis

    A patient with a 30-year history of RA, well controlled with methotrexate therapy, presented with new-onset seizures.[] […] mild temporal pallor.[] Two hours prior to admission, he developed epileptic seizures. Brain computed tomography and magnetic resonance imaging showed intracerebral malacic lesions.[]

  • Leber's Hereditary Optic Neuropathy

    Dravet's severe myoclonic epilepsy in infancy is especially interesting as it is associated with fever-provoked seizures and mutations in the alpha subunit of the sodium channel[] Fundoscopic exam revealed the development of temporal optic nerve pallor with loss of hyperemia OU (Figure 5).[] She died of bronchopneumonia at the age of 44 years, after a disease duration of 19 years, with progressive deterioration, epileptic seizures and immobility.[]

  • Familial Dysautonomia

    […] attractive modification for patients where the fundoplication may be under continued physical stress caused by autonomic perturbations, or other conditions such as uncontrolled seizures[] Temporal optic nerve pallor was present in all cases and was associated with retinal nerve fiber layer loss in the papillomacular region.[] Constipation or diarrhea Inability to feel pain and changes in temperature (can lead to injuries) Dry eyes and lack of tears when crying Poor coordination and unsteady walk Seizures[]

  • Spinocerebellar Ataxia, Type 2

    Two had focal epilepsy with complex partial seizures and epileptiform discharges on electroencephalography.[] His retinal examination suggested foveal atrophy, with bilateral parafoveal pigmentary changes, and mild temporal pallor of the optic nerves ( Figure 2 ).[] In severe cases, SCA 2 can cause developmental delay, seizures, and difficulty swallowing even in infancy.[]

  • Optic Atrophy

    Of interest, de novo SCN2A mutations have also been reported in five patients without seizures but with ID (n 3) and/or autism (n 3).[] Fundus examination revealed bilateral temporal optic nerve pallor in both patients with otherwise normal retinal findings.[] Temporal pallor of the optic nerve head may indicate atrophy of fibres of the papillomacular bundle, and is classically seen following demyelinating optic neuritis.[]

  • Pituitary Adenoma

    Toxicity: New pituitary deficits 38%; no visual complications, seizures, brain injury or secondary tumors Conclusion: Proton SRS effective for persistent acromegaly, with[] 1) Figure 1 : Color fundus photographs, revealing temporal optic nerve pallor OU.[] Extremely large pituitary tumors can even cause pressure on the brain, leading to seizures or blockage of the normal flow of cerebrospinal fluid (a condition called hydrocephalus[]

  • Strabismus

    It is much more common in children with a neurological risk - prematurely born, seizures, cerebral palsy, developmental delay, chromosomal disorders, etc.[] Six (21.4%) patients had temporal disc pallor, six (21.4%) patients had optic nerve hypoplasia, and seven (25%) patients had other optic disc anomalies (tilted disc, megalodisc[] […] suggested that there is a significant difference in results and surgical effects among developmentally delayed children including those with cerebral palsy, hydrocephalus, seizure[]

  • Autosomal Recessive Optic Atrophy Type 7

    Exonic) Ataxin2 Ataxia with slow saccades, ophthalmoplegia, and minimal pyramidal and extrapyramidal findings, levodopa-responsive parkinsonism, tremor, chorea, myoclonus, seizures[] Fundus examination revealed bilateral temporal optic nerve pallor in both patients with otherwise normal retinal findings.[] Both optic nerve heads present temporal pallor as seen on fundus photography and those are often more prominent at red-free fundus photo.[]

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