Selective Tooth Agenesis: Causes & Reasons

Possible Causes for Selective Tooth Agenesis

tooth agenesis Short chin Skeletal muscle atrophy Stridor Wide nasal bridge Wrist flexion contracture Based on the frequency of symptoms observed, the following information [dovemed.com]

tooth agenesis 0001592 Short chin Decreased height of chin Short lower third of face [ more ] 0000331 Skeletal muscle atrophy Muscle degeneration Muscle wasting [ more ] [rarediseases.info.nih.gov]

[…] magnum Long foot Long phalanx of finger Mitral valve prolapse Partial fusion of carpals Partial fusion of tarsals Persistence of primary teeth Pointed chin Scapular winging Selective [dovemed.com]

Seckel Syndrome

tooth agenesis 0001592 Single transverse palmar crease 0000954 Sloping forehead Inclined forehead Receding forehead [ more ] 0000340 Small anterior fontanelle 0000237 Small [rarediseases.info.nih.gov]

agenesis, selective type 1 MSX1 Tooth agenesis, selective type 3 PAX9 Townes-Brocks syndrome SALL1 Transposition of great arteries, dextro-looped 3 GDF1 Transposition of [centogene.com]

Disproportionately large nose Increased nasal size Increased size of nose Large nose Pronounced nose [ more ] 0000448 Proportionate short stature 0003508 Seizures Seizure 0001250 Selective [rarediseases.info.nih.gov]

Hallermann-Streiff Syndrome

tooth agenesis 0001592 Slender long bone Long bones slender Thin long bones [ more ] 0003100 Small for gestational age Birth weight less than 10th percentile Low birth weight [rarediseases.info.nih.gov]

tooth agenesis　(選択的歯無発生)　[HP:0001592]　[08301] 　Slender long bone　(細い長管骨)　[HP:0003100]　[160012] 　Small for gestational age　(低出生体重)　[HP:0001518]　[0111] 　Sparse hair　(疎な毛髪)　 [syndromefinder.ncchd.go.jp]

[…] infections respiratory infections, recurrent Susceptibility to respiratory infections [ more ] 0002205 Scaphocephaly 0030799 Scoliosis Abnormal curving of the spine 0002650 Selective [rarediseases.info.nih.gov]

Dental Disorder

Abstract A door to door survey on oro-dental disorders was carried out in four villages of the field practice area of Rural Health Training Centre, Naila (Jaipur), covering a population of 1384 in the age group of 6 years and above. A total of 81 (5.85 per cent) of the examined population had malocclusion, and its[…] [ncbi.nlm.nih.gov]

Bloch Sulzberger Syndrome

Incontinentia pigmenti (Bloch-Sulzberger syndrome). Authors: Handb Clin Neurol 2015 ;132:271-80 Neurology Research, Barrow Neurological Institute, Phoenix, AZ, USA; Center for Rare Childhood Disorders, Translational Genomics Research Institute, Phoenix, AZ, USA; Arizona Pediatric Neurology and Neurogenetics Associates,[…] [pubfacts.com]

Odonto-Onycho-Dermal Dysplasia

Tooth agenesis, selective, 4 (STHAG4) [MIM:150400]: A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. [genecards.org]

The WNT10A gene in Ectodermal Dysplasias and Selective Tooth Agenesis. Am J Med Genet A. 2014;164:2455–60. CrossRef PubMedCentral 9. [springermedizin.de]

The WNT10A gene in Ectodermal Dysplasias and Selective Tooth Agenesis. Am J Med Genet A. 2014;164:2455–60. [bmcdermatol.biomedcentral.com]

Amelogenesis Imperfecta Type 2A5

tooth agenesis) Alopecia, neurologic defects, and endocrinopathy syndrome (Carious teeth) Amelogenesis imperfecta, hypomaturation type IIA5 (Carious teeth) Amelogenesis imperfecta [familydiagnosis.com]

agenesis selective 3,604625 MSX1 Tooth agenesis,selective,1,with or without orofacial cleft,106600 WNT10A Tooth agenesis,selective,4,150400 EDA Tooth agenesis,selective,X-linked [gsdseq.ir]

agenesis,selective,x-linked 1, EDAR % 100% Ectodermal dysplasia 10A,hypohidrotic/hair/nail type, autosomal dominant, Ectodermal dysplasia 10B,hypohidrotic/hair/tooth type [docplayer.net]

Thoracomelic Dysplasia

Agenesis, Selective, 1; STHAG1 OMIM:602639 Tooth Agenesis, Selective, 2; STHAG2 OMIM:604625 Tooth Agenesis, Selective, 3; STHAG3 OMIM:150400 Tooth Agenesis, Selective, 4; [informatics.jax.org]

STHAG4 OMIM:610926 Tooth Agenesis, Selective, 5; STHAG5 OMIM:616724 Tooth Agenesis, Selective, 7; STHAG7 OMIM:617073 Tooth Agenesis, Selective, 8; STHAG8 OMIM:617275 Tooth [informatics.jax.org]

Agenesis, Selective, 9; STHAG9 OMIM:313500 Tooth Agenesis, Selective, X-Linked, 1; STHAGX1 OMIM:613600 Torsade De Pointes, Short-Coupled Variant OMIM:602554 Torsion Dystonia [informatics.jax.org]

Congenital Hypotrichosis with Juvenile Macular Dystrophy

It is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with [genecards.org]

Selective Tooth Agenesis

4 Selective Tooth Agenesis 5 Selective Tooth Agenesis 7 Selective Tooth Agenesis 8 Selective Tooth Agenesis 9 Selective Tooth Agenesis with Orofacial Cleft Selective Tooth [rgd.mcw.edu]

Abstract Previously, we found that the cause of autosomal dominant selective tooth agenesis in one family is a missense mutation resulting in an arginine-to-proline substitution [ncbi.nlm.nih.gov]

We also present a new mutation in the EDA gene which causes selective tooth agenesis and demonstrates the phenotype variation that can be encountered in the ectodermal dysplasia [ncbi.nlm.nih.gov]

X-Linked Selective Tooth Agenesis Type 1

Genes Dev 1998; 12: 2735–2747. 21 Hu G, Vastardis H, Bendall AJ et al: Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis. [nature.com]

A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet 1996;13:417-421. [ Links ] 9. Boeira BR, Echeverrigaray S. [scielo.br]

A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet 13:417-421. [journals.sagepub.com]

Oligodontia-Cancer Predisposition Syndrome

Vastardis H, Karimbux N, Guthua SW et al. (1996) A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nature Genetics 13(4): 417–421. [els.net]

tooth agenesis. [genecards.org]

Axis inhibition protein 2 (AXIN2) polymorphisms may be a risk factor for selective tooth agenesis. Mostowska A, Biedziak B, Jagodzinski PP. [dentistry3000.pitt.edu]

Autosomal Recessive Hypohidrotic Ectodermal Dysplasia Type 10B

Genetic Heterogeneity of Selective Tooth Agenesis Other forms of selective tooth agenesis include STHAG2 (602639), mapped to chromosome 16q12; STHAG3 (604625), caused by mutation [ncbi.nlm.nih.gov]

agenesis, selective, 1, with or without orofacial cleft, 106600 PAX9 Tooth agenesis, selective, 3, 604625 WNT10A Tooth agenesis, selective, 4, 150400 LTBP3 Tooth agenesis [gsdseq.ir]

agenesis, selective, X-linked 1, 3 EDAR % 100% Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant, Ectodermal dysplasia 10B, hypohidrotic/hair/tooth [docplayer.net]

Levy-Hollister Syndrome

A type of selective tooth agenesis that was formerly designated STHAG6 has been incorporated into the dental anomalies and short stature syndrome (DASS; 601216). [ncbi.nlm.nih.gov]

Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and [ncbi.nlm.nih.gov]

Congenital Disorder of Glycosylation Type 2H

Morning glory disc anomaly, 120430 PAX7 115.6 0.99 0.99 Rhabdomyosarcoma 2 alveolar, 268220 PAX9 254.3 0.99 0.98 Tooth agenesis, selective, 3 604625 PITX2 155.7 0.99 0.97 [qgenomics.com]

agenesis, selective, X-linked 1 313500 EDAR 145.9 0.99 0.98 Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant, 129490 EDAR 145.9 0.99 0.98 Ectodermal [qgenomics.com]

agenesis, selective, 7 616724 LRP6 186.6 1 0.99 {Coronary artery disease, autosomal dominant, 2}, 610947 LTBP3 126.4 0.98 0.96 Dental anomalies and short stature, 601216 [qgenomics.com]

Seckel Syndrome Type 5

A type of selective tooth agenesis that was formerly designated STHAG6 has been incorporated into the dental anomalies and short stature syndrome (DASS; 601216). [ncbi.nlm.nih.gov]

Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and [ncbi.nlm.nih.gov]

Dermo-Odonto Dysplasia

The WNT10A gene in Ectodermal Dysplasias and Selective Tooth Agenesis. Am J Med Genet A. 2014;164:2455–60. CrossRef PubMedCentral 9. [springermedizin.de]

The WNT10A gene in ectodermal dysplasias and selective tooth agenesis. Am J Med Genet A. 2014 Oct. 164A (10):2455-60. [Medline]. [emedicine.medscape.com]

Trichoodontoonychial Dysplasia

Tooth agenesis, selective, 4 (STHAG4) [MIM:150400]: A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. [genecards.org]

The WNT10A gene in Ectodermal Dysplasias and Selective Tooth Agenesis. Am J Med Genet A. 2014;164:2455–60. CrossRef PubMedCentral 9. [springermedizin.de]

Congenital Disorder of Glycosylation Type 1L

Morning glory disc anomaly, 120430 PAX7 115.6 0.99 0.99 Rhabdomyosarcoma 2 alveolar, 268220 PAX9 254.3 0.99 0.98 Tooth agenesis, selective, 3 604625 PITX2 155.7 0.99 0.97 [qgenomics.com]

agenesis, selective, X-linked 1 313500 EDAR 145.9 0.99 0.98 Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant, 129490 EDAR 145.9 0.99 0.98 Ectodermal [qgenomics.com]

agenesis, selective, 7 616724 LRP6 186.6 1 0.99 {Coronary artery disease, autosomal dominant, 2}, 610947 LTBP3 126.4 0.98 0.96 Dental anomalies and short stature, 601216 [qgenomics.com]

Axenfeld-Rieger Syndrome Type 1

A type of selective tooth agenesis that was formerly designated STHAG6 has been incorporated into the dental anomalies and short stature syndrome (DASS; 601216). [ncbi.nlm.nih.gov]

Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and [ncbi.nlm.nih.gov]

Axenfeld-Rieger Syndrome Type 2

A type of selective tooth agenesis that was formerly designated STHAG6 has been incorporated into the dental anomalies and short stature syndrome (DASS; 601216). [ncbi.nlm.nih.gov]

Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and [ncbi.nlm.nih.gov]

Absent Tibia - Polydactyly - Arachnoid Cyst Syndrome

Seckel Syndrome Type 2

agenesis, selective type 1 MSX1 Tooth agenesis, selective type 3 PAX9 Townes-Brocks syndrome SALL1 Transposition of great arteries, dextro-looped 3 GDF1 Transposition of [centogene.com]

Faciocardiomusculoskeletal Syndrome Type Uruguay

DENTAL ANOMALIES AND SHORT STATURE; DASS Is also known as platyspondyly with amelogenesis imperfecta, tooth agenesis, selective, 6, formerly;sthag6, formerly;platyspondyly-amelogenesis [mendelian.co]

tooth agenesis Thick nasal alae Congestive heart failure Retrognathia Wide mouth Camptodactyly of toe EEG abnormality Macrocephaly Epicanthus Cognitive impairment Ataxia [mendelian.co]

Arrhythmia Talipes equinovarus Hyperreflexia Herniation of intervertebral nuclei Short first metatarsal Intervertebral space narrowing Narrow vertebral interpedicular distance Selective [mendelian.co]

Joubert Syndrome Type 18

agenesis, selective, X-linked 1 313500 EDN3 20q13.32 Central hypoventilation syndrome, congenital 209880 Waardenburg syndrome, type 4B 613265 EDNRB 13q22.3 ABCD syndrome [institutobernabeu.com]

agenesis, selective, 4 150400 WNT3 17q21.31 Tetra-amelia syndrome 273395 WNT7A 3p25.1 Fuhrmann syndrome 228930 Ulna and fibula, absence of, with severe limb deficiency 276820 [institutobernabeu.com]

313900 Thrombocytopenia, X-linked, intermittent 313900 Wiskott-Aldrich syndrome 301000 WNT10A 2q35 Odontoonychodermal dysplasia 257980 Schopf-Schulz-Passarge syndrome 224750 Tooth [institutobernabeu.com]

Hirschsprung Disease Type D-Brachydactyly Syndrome

agenesis, selective type 1 MSX1 Tooth agenesis, selective type 3 PAX9 Townes-Brocks syndrome SALL1 Transposition of great arteries, dextro-looped 3 GDF1 Transposition of [centogene.com]

1 2 Tooth Agenesis, Selective, 3 2 Tooth Agenesis, Selective, 4 3 Tooth Agenesis, Selective, X-Linked, 1 3 Torg Winchester Syndrome 1 Townes-Brocks Syndrome 4 Traboulsi [preventiongenetics.com]

WNT3 Three M syndrome type 1 CUL7 Three M syndrome type 2 OBSL1 Three M syndrome type 3 CCDC8 Toe syndactyly, telecanthus, and anogenital and renal malformations FAM58A Tooth [centogene.com]

Spondyloepimetaphyseal Dysplasia Type Bieganski

A type of selective tooth agenesis that was formerly designated STHAG6 has been incorporated into the dental anomalies and short stature syndrome (DASS; 601216). [ncbi.nlm.nih.gov]

Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and [ncbi.nlm.nih.gov]

Congenital Ankyloblepharon

Tooth Agenesis with Orofacial Cleft Seres-Santamaria Arimany Muniz Syndrome Short Stature, Mental Retardation, Callosal Agenesis, Heminasal Hypoplasia, Microphthalmia, and [rgd.mcw.edu]

Tooth Agenesis with Orofacial Cleft Sener Syndrome Sensenbrenner syndrome + Seres-Santamaria Arimany Muniz Syndrome Short Stature, Mental Retardation, Callosal Agenesis, [rgd.mcw.edu]

The WNT10A gene in ectodermal dysplasias and selective tooth agenesis. Am J Med Genet A. 2014 Oct. 164A (10):2455-60. [Medline]. [emedicine.medscape.com]

Filippi Syndrome

A type of selective tooth agenesis that was formerly designated STHAG6 has been incorporated into the dental anomalies and short stature syndrome (DASS; 601216). [ncbi.nlm.nih.gov]

Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and [ncbi.nlm.nih.gov]

Parietal Foramina with Cleidocranial Dysplasia

selective, 6, 613097 EDA Tooth agenesis, selective, X-linked 1, 313500 TCOF1 Treacher Collins syndrome 1, 154500 POLR1D Treacher Collins syndrome 2, 613717 POLR1C Treacher [gsdseq.ir]

186570 DISP1 Tetralogy of Fallot (Silversides (2012) PLoS Genet 8, e1002843) FGFR3 Thanatophoric dysplasia, type I, 187600 FGFR3 Thanatophoric dysplasia, type II, 187601 MSX1 Tooth [gsdseq.ir]