Sensorimotor Neuropathy: Causes & Reasons

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Possible Causes for Sensorimotor Neuropathy

Cirrhosis-Dystonia-Polycythemia-Hypermanganesemia Syndrome

Signs and Symptoms Sensorimotor neuropathy ... ... [familydiagnosis.com]

neuropathy Diarrhea Hepatic fibrosis Ascites Macrovesicular hepatic steatosis Proximal muscle weakness Progressive Hyporeflexia Edema Skeletal myopathy Exercise intolerance [mendelian.co]

Lethargy Dysphagia Acute hepatic failure Myalgia Tics Hypertension Portal fibrosis Ketosis Jaundice Areflexia Abdominal distention Hepatosplenomegaly Distal muscle weakness Sensorimotor [mendelian.co]

Polyneuropathy

neuropathies, (3) pure motor axonal neuropathies, (4) sensorimotor axonal neuropathies, or (5) pure sensory axonal neuropathies. [jnnp.bmj.com]

An axonal sensorimotor neuropathy may be present in midlife as documented by nerve conduction studies. MRIs of the brain may reveal cerebellar atrophy. [disorders.eyes.arizona.edu]

It can also affect both, in which case it is called a sensorimotor neuropathy. [pennstatehershey.adam.com]

Peripheral Neuropathy

Axonal sensorimotor neuropathy Chronic idiopathic ataxic neuropathy Demyelinating sensorimotor neuropathy Disease related peripheral neuropathy Idiopathic chronic neuropathy [icd9data.com]

Motor or sensorimotor neuropathies were more common than pure sensory neuropathies. [ncbi.nlm.nih.gov]

Multifocal motor or sensorimotor neuropathies and a more fulminant neuropathy, associated with ataxia and other neurologic manifestations, also have been reported. [ncbi.nlm.nih.gov]

Neuropathy

Axonal sensorimotor neuropathy Chronic idiopathic ataxic neuropathy Demyelinating sensorimotor neuropathy Disease related peripheral neuropathy Idiopathic chronic neuropathy [icd9data.com]

Charcot-Marie-Tooth disease comprises a vast array of defects in myelin integrity that causes progressive peripheral sensorimotor neuropathy. [ncbi.nlm.nih.gov]

Our report is the first to document a case of autopsy-confirmed NIID involving both cognitive impairment and sensorimotor neuropathy. [ncbi.nlm.nih.gov]

AMACR Deficiency

neuropathy. [symptoma.com]

It is characterized by neurological abnormalities that appear in adulthood and include cognitive decline, seizures, and sensorimotor neuropathy. [ http://www.ebi.ac.uk/ontology [ebi.ac.uk]

Late-onset CBAS4 is characterized by neurological symptoms, e.g., sensorimotor neuropathy, ataxia and dysarthria, seizures and cognitive decline. [symptoma.com]

Diabetic Polyneuropathy

The primary types of diabetic neuropathy are sensorimotor and autonomic. [aafp.org]

Chronic sensorimotor neuropathy is by far the most common form of DPN. [clinical.diabetesjournals.org]

C 24 Classification of Diabetic Neuropathy The primary types of diabetic neuropathy are sensorimotor and autonomic ( Table 1 ). [aafp.org]

Cogan Syndrome

Cerebellar ataxia with cerebellar atrophy on MRI and severe axonal sensorimotor neuropathy were present in all patients. [ncbi.nlm.nih.gov]

AOA1 is associated with oculomotor apraxia, severe sensorimotor neuropathy, choreiform movements, cognitive impairment, and cerebellar atrophy at an early age. [ncbi.nlm.nih.gov]

We report a novel PNKP mutation in two siblings with progressive ataxia, abnormal saccades, sensorimotor neuropathy and dystonia consistent with the AOA type 4 phenotype. [jhu.pure.elsevier.com]

Charcot-Marie-Tooth Disease

The proband, evaluated at age 31, showed delayed motor milestones that, as of the second decade, evolved into severe phenotype consisting of sensorimotor neuropathy, pes cavus [ncbi.nlm.nih.gov]

neuropathy. [ncbi.nlm.nih.gov]

The electrophysiological studies showed a mixed demyelinating and axonal sensorimotor neuropathy. [ncbi.nlm.nih.gov]

Arsenic-Induced Polyneuropathy

They most commonly cause a distal, symmetric axonal sensorimotor neuropathy. [aafp.org]

[…] metal titers Arsenic causes sensorimotor neuropathy Gold may cause some demyelination Organophosphates A Sensorimotor No specific or practical laboratory test Tetanus A Motor [aafp.org]

Associated disorders include Guillain-Barré syndrome, diphtheritic polyneuropathy, and porphyritic neuropathy. Subacute sensorimotor paralysis. [medical-dictionary.thefreedictionary.com]

Toxic Polyneuropathy

neuropathy, peripheral sensory neuropathy, neuralgia, decreased vibratory sense, polyneuropathy, sensory loss, amyotrophy, peripheral motor neuropathy, peripheral sensorimotor [kyprolis.eu]

Axonal Neuropathy / Polyneuropathy Sensory Neuropathy / Polyneuropathy Multifocal Motor Neuropathy (MMN) Multifocal Demyelinating Sensorimotor Neuropathy (Lewis Summer Syndromes [neuropathysupportnetwork.org]

They most commonly cause a distal, symmetric axonal sensorimotor neuropathy. [aafp.org]

Paraneoplastic Neurologic Syndrome

The cause of these episodes is unknown. 90 Paraneoplastic sensorimotor neuropathies Paraneoplastic sensorimotor neuropathies that precede the diagnosis of lymphomas are mainly [bloodjournal.org]

sensorimotor neuropathy, and cortical and neuropsychiatric manifestations. [questdiagnostics.com]

[…] and autonomic neuropathies. [ncbi.nlm.nih.gov]

Paraneoplastic Polyneuropathy

High titer IgM antibodies to MAG are associated with sensorimotor demyelinating peripheral neuropathy. [clinlabnavigator.com]

At least 15% of patients with cancer develop a paraneoplastic sensorimotor neuropathy, which is usually mild and develops during the terminal stage of the disease. 1 There [jnnp.bmj.com]

neuropathies, GI dysmotility SCLC CV2 (CRMP5) PN, limbic encephalitis, ataxia, chorea, optic neuritis SCLC, thymoma Amphiphysin Encephalomyelitis, neuropathy, stiff-person [arupconsult.com]

Peripheral Motor Neuropathy

Axonal sensorimotor neuropathy Chronic idiopathic ataxic neuropathy Demyelinating sensorimotor neuropathy Disease related peripheral neuropathy Idiopathic chronic neuropathy [icd9data.com]

They most commonly cause a distal, symmetric axonal sensorimotor neuropathy. [aafp.org]

CANOMAD Syndrome

High titer IgM antibodies to MAG are associated with sensorimotor demyelinating peripheral neuropathy. [clinlabnavigator.com]

When this initial phase is survived sensorimotor neuropathy becomes apparent in a few days. [neuroweb.us]

The majority of cases showed a sensorimotor demyelinating peripheral neuropathy, with predominantly sensory involvement. [omicsonline.org]

Autosomal Recessive Spinocerebellar Ataxia

[…] peripheral neuropathy, and increased serum alpha-fetoprotein (AFP; {104150}). [diseaseinfosearch.org]

/senataxin 7–25 years Oculomotor apraxia, axonal sensorimotor neuropathy, increased serum α-fetoprotein ARSACS SACS /sacsin Childhood Spastic ataxia, sensorimotor neuropathy [e-jmd.org]

neuropathy with progressive axonal degeneration, and involvement of the central sensory and motor pathways. [acnr.co.uk]

Charcot-Marie-Tooth Disease Type 2S

neuropathy, characterized by distal legs sensory loss and weakness that can be asymmetric. [ebi.ac.uk]

[…] synonyms: HMSN, CMT, Hereditary Sensorimotor Neuropathy, HNPP, hereditary neuropathy with predisposition for pressure palsy, Hereditary motor and sensory neuropathy Charcot-Marie-Tooth [eorif.com]

The complete clinical presentation was a sensorimotor neuropathy with trophic changes, but several points have to be emphasised: a late onset was found in most of the patients [jnnp.bmj.com]

Familial Progressive Polyneuropathy

They most commonly cause a distal, symmetric axonal sensorimotor neuropathy. [aafp.org]

[…] metal titers Arsenic causes sensorimotor neuropathy Gold may cause some demyelination Organophosphates A Sensorimotor No specific or practical laboratory test Tetanus A Motor [aafp.org]

When this initial phase is survived sensorimotor neuropathy becomes apparent in a few days. [neuroweb.us]

Autosomal Recessive Spastic Paraplegia Type 57

neuropathy. [orpha.net]

Familial transthyretin amyloidosis is characterized by a slowly progressive peripheral sensorimotor neuropathy and autonomic neuropathy as well as non-neuropathic changes [centogene.com]

AT is distinguished from FA by this atrophy, and by the axonal sensorimotor neuropathy observed in these patients. [elsevier.es]

Non-Neuropathic Heredofamilial Amyloidosis

Blood tests for common causes of neuropathy and neuroimaging were unrevealing. [ng.neurology.org]

Sympathetic skin response was absent from lower limb suggestive of autonomic neuropathy in lower limbs. MRI of brain and spine was normal. [japi.org]

Symptomatic treatments are essential for sensorimotor and autonomic neuropathy and visceral complications. Prognosis FAP is a severe and disabling disease. [orpha.net]

Diabetic Mononeuropathy

The primary types of diabetic neuropathy are sensorimotor and autonomic. [aafp.org]

Classification of Diabetic Neuropathies Generalized neuropathies • Chronic sensorimotor polyneuropathy • Autonomic neuropathy • Small fiber neuropathy • Hyperglycemic neuropathy [medlink.com]

Hyperglycemic neuropathy (acute) Generalised symmetrical polyneuropathies Sensory neuropathy Sensorimotor neuropathy (chronic, symmetric) Autonomic neuropathy (cardiovascular [physio-pedia.com]

Mitochondrial Trifunctional Protein Deficiency

Some patients with MTP deficiency show a protracted progressive course associated with myopathy, recurrent rhabdomyolysis, and sensorimotor axonal neuropathy. [liquisearch.com]

[…] poly-neuropathy with episodic rhabdomyolysis. [ncbi.nlm.nih.gov]

[…] trifunctional protein deficiency that may begin after infancy include hypotonia, muscle pain, a breakdown of muscle tissue, and a loss of sensation in the extremities (peripheral neuropathy [liquisearch.com]

Autosomal Recessive Spinocerebellar Ataxia 18

/senataxin 7–25 years Oculomotor apraxia, axonal sensorimotor neuropathy, increased serum α-fetoprotein ARSACS SACS /sacsin Childhood Spastic ataxia, sensorimotor neuropathy [e-jmd.org]

neuropathy. 1 Dystonia, chorea, and cognitive impairment are commonly associated symptoms, and hypoalbuminemia and hypercholesterolemia are often observed. 2 AOA1 is caused [synapse.koreamed.org]

neuropathy with progressive axonal degeneration, and involvement of the central sensory and motor pathways. [acnr.co.uk]

Ataxia-Oculomotor Apraxia Syndrome

An autosomal recessive condition characterised by onset between age 3 and 30, cerebellar atrophy, axonal sensorimotor neuropathy, oculomotor apraxia and elevated serum alpha-fetoprotein [medical-dictionary.thefreedictionary.com]

The diagnosis of hereditary sensorimotor neuropathy (HSMN) was suspected. [academic.oup.com]

Ataxia with oculomotor apraxia type 2 (AOA2) is clinically characterized by onset between age three and 30 years, cerebellar atrophy, axonal sensorimotor neuropathy, oculomotor [centogene.com]

Diabetic Pseudotabes

neuropathies, eg. peroneal muscular atrophy · lateral popliteal nerve palsy (mononeuropathy): trauma · heavy metal poisoning (rare) waddling gait (wasting disorders of pelvic [sinoemedicalassociation.org]

Classifications Distal Symmetric Polyneuropathy: Mixed sensorimotor neuropathy with some autonomic features (approximately 70% of all diabetic neuropathy) Predominantly sensory [neurodiffdx.com]

[…] or amputation  Severe nail pathology DISTAL SENSORIMOTOR POLYNEUROPATHY COMPLICATION 9 DISTAL SENSORIMOTOR POLYNEUROPATHY 10  Pure autonomic neuropathy  Range from subclinical [slideplayer.com]

Uremic Neuropathy

Uremic neuropathy is a symmetric, mixed sensorimotor neuropathy, with longer axons being affected first. [symptoma.com]

distal, symmetrical, mixed sensorimotor neuropathy - distal, symmetrical, mixed sensorimotor neuropathy - independent underlying disease - independent underlying disease [slideplayer.com]

Historical note and terminology Uremic neuropathy is a distal sensorimotor polyneuropathy caused by uremic toxins. [medlink.com]

Spinocerebellar Ataxia with Axonal Neuropathy

Ataxia with oculomotor apraxia type 2 (AOA2) is clinically characterized by onset between age three and 30 years, cerebellar atrophy, axonal sensorimotor neuropathy, oculomotor [centogene.com]

/senataxin 7–25 years Oculomotor apraxia, axonal sensorimotor neuropathy, increased serum α-fetoprotein ARSACS SACS /sacsin Childhood Spastic ataxia, sensorimotor neuropathy [e-jmd.org]

When this initial phase is survived sensorimotor neuropathy becomes apparent in a few days. [neuroweb.us]

Distal Spinal Muscular Atrophy Type 4

No No Foot deformity Yes Yes Scoliosis No Yes Respiratory dysfunction No Yes (60%) Wheelchair bound No Yes (80%) Nerve conduction study Sensorimotor neuropathy Motor neuropathy [ojrd.biomedcentral.com]

Less frequently, seizures, sensorimotor demyelinating peripheral neuropathy and premature cardiovascular disease may occur. [neuroweb.us]

CMT 2D is a confusing disorder because some patients have sensorimotor neuropathies, while others have only motor symptoms. [cmtausa.org]

Diabetic Neuropathy

The excruciating, refractory pain that can accompany sensorimotor neuropathy is what most health care providers recognize as diabetic neuropathy; however, the damage typically [medscape.com]

Final Notes People with diabetic sensorimotor neuropathy and drop foot are in a precarious state of health. [podiatrytoday.com]

The primary types of diabetic neuropathy are sensorimotor and autonomic. [aafp.org]

Diphtheritic Neuropathy

autonomic neuropathy. 4 Uraemia Uraemia Progressive sensorimotor neuropathy develops in chronic uraemia. [slideplayer.com]

Miscellaneous neuropathies • Diabetic neuropathy ◦ Wide variety of diseases may be encountered: distal symmetric or sensorimotor neuropathy, autonomic neuropathy (2040% of [alpfmedical.info]

[…] and a sensorimotor neuropathy occur several weeks after the throat infection. [slideplayer.com]

Peripheral Sensory Neuropathy

neuropathy, peripheral sensory neuropathy, neuralgia, decreased vibratory sense, polyneuropathy, sensory loss, amyotrophy, peripheral motor neuropathy, peripheral sensorimotor [kyprolis.eu]

It can also affect both, in which case it is called a sensorimotor neuropathy. [medlineplus.gov]

Associated disorders include Guillain-Barré syndrome, diphtheritic polyneuropathy, and porphyritic neuropathy. Subacute sensorimotor paralysis. [medical-dictionary.thefreedictionary.com]