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3 Possible Causes for Sensorineural Deafness Especially Affecting High Frequencies

  • Autosomal Recessive Alport Syndrome

    BACKGROUND: Genetic heterogeneity is a well-known feature of Alport syndrome (AS). Most families with AS show an X-linked dominant pattern of inheritance but about 15% of families show an autosomal inheritance of the disease. Autosomal recessive AS may account for 10% of the total number of cases and is caused[…][]

  • X-Linked Diffuse Leiomyomatosis-Alport Syndrome
  • Autosomal Dominant Alport Syndrome

    Abstract Most patients with Alport syndrome have X-linked or autosomal recessive disease that is characterised by renal failure, hearing loss, and, in nearly 75% of the cases, a dot-and-fleck retinopathy and anterior lenticonus. There are only case reports of individuals with the rare autosomal dominant form, who[…][]

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